| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | RA Capital Management, LLC | 10.23M (38.66%) | -1.38M Decreased by -13.50% | Sep 30, 24 |
| 2 | RTW INVESTMENTS, LLC | 5.85M (22.09%) | 0.00 Increased by 0.00% | Jun 30, 24 |
| 3 | BlackRock Inc | 5.71M (21.56%) | 908.00K Increased by +15.91% | Sep 30, 24 |
| 4 | TCG Crossover Management, LLC | 5.25M (19.84%) | 5.25M Increased by +100.00% | Sep 30, 24 |
| 5 | Nantahala Capital Management, LLC | 4.78M (18.06%) | 4.78M Increased by +100.00% | Sep 30, 24 |
| 6 | Vanguard Group Inc | 3.27M (12.37%) | 203.45K Increased by +6.21% | Sep 30, 24 |
| 7 | COWEN AND COMPANY, LLC | 2.96M (11.20%) | -749.81K Decreased by -25.30% | Jun 30, 24 |
| 8 | Morgan Stanley - Brokerage Accounts | 2.47M (9.33%) | 155.35K Increased by +6.29% | Jun 30, 24 |
| 9 | TRV GP IV, LLC | 2.34M (8.85%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 10 | Adage Capital Partners Gp LLC | 2.00M (7.56%) | 1.70M Increased by +85.00% | Sep 30, 24 |
| 11 | FMR Inc | 1.72M (6.51%) | -3.61M Decreased by -209.16% | Sep 30, 24 |
| 12 | State Street Corp | 1.68M (6.35%) | 638.96K Increased by +38.03% | Sep 30, 24 |
| 13 | MPM Oncology Impact Management LP | 1.44M (5.46%) | 307.74K Increased by +21.30% | Jun 30, 24 |
| 14 | Jefferies Financial Group Inc | 1.43M (5.42%) | 281.59K Increased by +19.65% | Jun 30, 24 |
| 15 | Dimensional Fund Advisors, Inc. | 1.42M (5.38%) | -57.43K Decreased by -4.03% | Sep 30, 24 |
| 16 | Citadel Advisors Llc | 1.35M (5.10%) | -428.32K Decreased by -31.76% | Sep 30, 24 |
| 17 | Geode Capital Management, LLC | 1.32M (4.99%) | 13.48K Increased by +1.02% | Sep 30, 24 |
| 18 | Logos Global Management LP | 1.20M (4.53%) | 1.20M Increased by +100.00% | Dec 31, 23 |
| 19 | Suvretta Capital Management, LLC | 1.18M (4.47%) | -1.36M Decreased by -114.83% | Sep 30, 24 |
| 20 | Vestal Point Capital LP | 1.16M (4.38%) | 465.00K Increased by +40.09% | Jun 30, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 1.85M (7.00%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 2 | Fidelity Growth Compy Commingled Pl O | 1.81M (6.85%) | 0.00 Increased by 0.00% | May 31, 24 |
| 3 | iShares Russell 2000 ETF | 1.72M (6.51%) | -261.00 Decreased by -0.02% | Jan 29, 25 |
| 4 | Fidelity® Select Biotechnology | 1.56M (5.89%) | -136.10K Decreased by -8.73% | Nov 30, 23 |
| 5 | Fidelity Select Biotechnology | 1.26M (4.74%) | 0.00 Increased by 0.00% | May 31, 24 |
| 6 | Fidelity® Growth Company | 869.67K (3.29%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 7 | Select Pharmaceuticals Port | 762.00K (2.88%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 8 | Fidelity Select Pharmaceuticals Port | 683.60K (2.58%) | 0.00 Increased by 0.00% | May 31, 24 |
| 9 | Fidelity Small Cap Index | 648.26K (2.45%) | 12.24K Increased by +1.89% | Nov 30, 24 |
| 10 | Vanguard Institutional Extnd Mkt Idx Tr | 583.96K (2.21%) | -198.51K Decreased by -33.99% | Dec 31, 24 |
| 11 | Fidelity Growth Compy Commingled Pl S | 494.64K (1.87%) | -295.57K Decreased by -59.75% | Nov 30, 24 |
| 12 | Fidelity® Growth Company K6 | 471.79K (1.78%) | -51.29K Decreased by -10.87% | Nov 30, 23 |
| 13 | Simplify Propel Opportunities ETF | 465.00K (1.76%) | 0.00 Increased by 0.00% | Jun 30, 24 |
| 14 | SPDR® S&P Pharmaceuticals ETF | 436.70K (1.65%) | 0.00 Increased by 0.00% | Nov 30, 24 |
| 15 | Invesco Dorsey Wright SmallCap Momt ETF | 380.63K (1.44%) | 0.00 Increased by 0.00% | Jun 30, 24 |
| 16 | State St Russell Sm/Mid Cp® Indx NL Cl C | 368.38K (1.39%) | -5.00K Decreased by -1.36% | Dec 31, 24 |
| 17 | Fidelity® Series Growth Company | 356.20K (1.35%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 18 | iShares Russell 2000 Value ETF | 326.01K (1.23%) | 0.00 Increased by 0.00% | Jan 29, 25 |
| 19 | iShares Biotechnology ETF | 317.82K (1.20%) | 0.00 Increased by 0.00% | Nov 30, 24 |
| 20 | Vanguard Russell 2000 ETF | 297.95K (1.13%) | 4.78K Increased by +1.61% | Dec 31, 24 |