| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Suvretta Capital Management, LLC | 6.56M (17.86%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 2 | RA Capital Management, LLC | 6.05M (16.48%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 3 | RTW INVESTMENTS, LLC | 5.85M (15.91%) | 0.00 Increased by 0.00% | Jun 30, 24 |
| 4 | BlackRock Inc | 5.39M (14.67%) | 1.13M Increased by +20.90% | Mar 31, 26 |
| 5 | TCG Crossover Management, LLC | 5.25M (14.29%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 6 | Vanguard Group Inc | 3.56M (9.69%) | 560.09K Increased by +15.73% | Dec 31, 25 |
| 7 | BRAIDWELL LP | 3.13M (8.53%) | 73.70K Increased by +2.35% | Mar 31, 26 |
| 8 | Nantahala Capital Management, LLC | 3.05M (8.30%) | -1.24M Decreased by -40.76% | Mar 31, 26 |
| 9 | COWEN AND COMPANY, LLC | 2.96M (8.07%) | -749.81K Decreased by -25.30% | Jun 30, 24 |
| 10 | Vanguard Capital Management, LLC | 2.69M (7.33%) | 2.69M Increased by +100.00% | Mar 31, 26 |
| 11 | Siren, L.L.C. | 2.35M (6.40%) | 400.00K Increased by +17.02% | Mar 31, 26 |
| 12 | TRV GP IV, LLC | 2.34M (6.38%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 13 | First Turn Management LLC | 2.26M (6.14%) | 363.43K Increased by +16.11% | Mar 31, 26 |
| 14 | Aberdeen Group PLC | 2.21M (6.02%) | 957.93K Increased by +43.31% | Mar 31, 26 |
| 15 | Point72 Asset Management, L.P. | 2.07M (5.65%) | -323.38K Decreased by -15.59% | Mar 31, 26 |
| 16 | GSK PLC | 1.79M (4.86%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 17 | Balyasny Asset Management LLC | 1.78M (4.85%) | 809.51K Increased by +45.48% | Mar 31, 26 |
| 18 | Jones Hill Capital LP | 1.77M (4.82%) | 1.77M Increased by +100.00% | Mar 31, 26 |
| 19 | FMR Inc | 1.72M (4.69%) | -3.61M Decreased by -209.16% | Sep 30, 24 |
| 20 | Adage Capital Partners Gp LLC | 1.70M (4.63%) | -732.00K Decreased by -43.06% | Dec 31, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 2.07M (5.65%) | 0.00 Increased by 0.00% | Apr 30, 26 |
| 2 | Vanguard US Total Market Shares ETF | 1.85M (5.04%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 3 | Fidelity Growth Compy Commingled Pl O | 1.81M (4.93%) | 0.00 Increased by 0.00% | May 31, 24 |
| 4 | abrdn Life Sciences Investors | 1.61M (4.38%) | 90.09K Increased by +5.60% | May 31, 26 |
| 5 | Fidelity® Select Biotechnology | 1.56M (4.24%) | -136.10K Decreased by -8.73% | Nov 30, 23 |
| 6 | iShares Russell 2000 ETF | 1.43M (3.89%) | 13.21K Increased by +0.92% | May 29, 26 |
| 7 | Fidelity Select Biotechnology | 1.26M (3.42%) | 0.00 Increased by 0.00% | May 31, 24 |
| 8 | abrdn Healthcare Investors | 877.11K (2.39%) | 183.66K Increased by +20.94% | May 31, 26 |
| 9 | Fidelity® Growth Company | 869.67K (2.37%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 10 | Select Pharmaceuticals Port | 762.00K (2.07%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 11 | Fidelity Select Pharmaceuticals Port | 683.60K (1.86%) | 0.00 Increased by 0.00% | May 31, 24 |
| 12 | Fidelity Small Cap Index | 587.83K (1.60%) | 165.63K Increased by +28.18% | Mar 31, 26 |
| 13 | Vanguard Institutional Extnd Mkt Idx Tr | 552.12K (1.50%) | 3.01K Increased by +0.54% | Apr 30, 26 |
| 14 | Fidelity Growth Compy Commingled Pl S | 494.64K (1.35%) | -295.57K Decreased by -59.75% | Nov 30, 24 |
| 15 | Fidelity® Growth Company K6 | 471.79K (1.28%) | -51.29K Decreased by -10.87% | Nov 30, 23 |
| 16 | iShares Russell 2000 Value ETF | 467.41K (1.27%) | 0.00 Increased by 0.00% | May 29, 26 |
| 17 | Simplify Propel Opportunities ETF | 465.00K (1.27%) | 0.00 Increased by 0.00% | Jun 30, 24 |
| 18 | SPDR® S&P Pharmaceuticals ETF | 436.70K (1.19%) | 0.00 Increased by 0.00% | Nov 30, 24 |
| 19 | iShares Biotechnology ETF | 419.78K (1.14%) | 8.05K Increased by +1.92% | May 29, 26 |
| 20 | BlackRock Advantage Small Cap Core Instl | 416.77K (1.13%) | 295.78K Increased by +70.97% | Apr 30, 26 |