| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | RA Capital Management, LLC | 10.23M (38.60%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 2 | RTW INVESTMENTS, LLC | 5.85M (22.06%) | 0.00 Increased by 0.00% | Jun 30, 24 |
| 3 | TCG Crossover Management, LLC | 5.25M (19.81%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 4 | BlackRock Inc | 5.17M (19.50%) | -537.10K Decreased by -10.39% | Dec 31, 24 |
| 5 | Nantahala Capital Management, LLC | 4.78M (18.03%) | 1.80K Increased by +0.04% | Dec 31, 24 |
| 6 | Suvretta Capital Management, LLC | 3.34M (12.60%) | 2.16M Increased by +64.57% | Dec 31, 24 |
| 7 | Vanguard Group Inc | 3.25M (12.26%) | -24.98K Decreased by -0.77% | Dec 31, 24 |
| 8 | Adage Capital Partners Gp LLC | 3.00M (11.32%) | 1.00M Increased by +33.33% | Dec 31, 24 |
| 9 | COWEN AND COMPANY, LLC | 2.96M (11.18%) | -749.81K Decreased by -25.30% | Jun 30, 24 |
| 10 | TRV GP IV, LLC | 2.34M (8.84%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 11 | FMR Inc | 1.72M (6.50%) | -3.61M Decreased by -209.16% | Sep 30, 24 |
| 12 | Morgan Stanley - Brokerage Accounts | 1.53M (5.78%) | 1.18M Increased by +77.11% | Dec 31, 24 |
| 13 | MPM Oncology Impact Management LP | 1.44M (5.45%) | 307.74K Increased by +21.30% | Jun 30, 24 |
| 14 | Jefferies Financial Group Inc | 1.43M (5.41%) | 281.59K Increased by +19.65% | Jun 30, 24 |
| 15 | Dimensional Fund Advisors, Inc. | 1.42M (5.35%) | -4.80K Decreased by -0.34% | Dec 31, 24 |
| 16 | Woodline Partners LP | 1.41M (5.32%) | 739.71K Increased by +52.44% | Dec 31, 24 |
| 17 | Geode Capital Management, LLC | 1.29M (4.88%) | -26.35K Decreased by -2.04% | Dec 31, 24 |
| 18 | State Street Corp | 1.25M (4.70%) | -434.91K Decreased by -34.92% | Dec 31, 24 |
| 19 | Logos Global Management LP | 1.20M (4.53%) | 1.20M Increased by +100.00% | Dec 31, 23 |
| 20 | Vestal Point Capital LP | 1.16M (4.38%) | 465.00K Increased by +40.09% | Jun 30, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 1.85M (6.99%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 2 | Fidelity Growth Compy Commingled Pl O | 1.81M (6.84%) | 0.00 Increased by 0.00% | May 31, 24 |
| 3 | iShares Russell 2000 ETF | 1.62M (6.12%) | -19.05K Decreased by -1.18% | Feb 28, 25 |
| 4 | Fidelity® Select Biotechnology | 1.56M (5.88%) | -136.10K Decreased by -8.73% | Nov 30, 23 |
| 5 | Fidelity Select Biotechnology | 1.26M (4.74%) | 0.00 Increased by 0.00% | May 31, 24 |
| 6 | Fidelity® Growth Company | 869.67K (3.28%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 7 | Select Pharmaceuticals Port | 762.00K (2.88%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 8 | Fidelity Select Pharmaceuticals Port | 683.60K (2.58%) | 0.00 Increased by 0.00% | May 31, 24 |
| 9 | Fidelity Small Cap Index | 648.26K (2.45%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 10 | Vanguard Institutional Extnd Mkt Idx Tr | 583.96K (2.20%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 11 | Fidelity Growth Compy Commingled Pl S | 494.64K (1.87%) | -295.57K Decreased by -59.75% | Nov 30, 24 |
| 12 | Fidelity® Growth Company K6 | 471.79K (1.78%) | -51.29K Decreased by -10.87% | Nov 30, 23 |
| 13 | Simplify Propel Opportunities ETF | 465.00K (1.75%) | 0.00 Increased by 0.00% | Jun 30, 24 |
| 14 | SPDR® S&P Pharmaceuticals ETF | 436.70K (1.65%) | 0.00 Increased by 0.00% | Nov 30, 24 |
| 15 | Invesco Dorsey Wright SmallCap Momt ETF | 380.63K (1.44%) | 0.00 Increased by 0.00% | Jun 30, 24 |
| 16 | State St Russell Sm/Mid Cp® Indx NL Cl C | 368.38K (1.39%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 17 | Fidelity® Series Growth Company | 356.20K (1.34%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 18 | iShares Russell 2000 Value ETF | 324.00K (1.22%) | -2.45K Decreased by -0.76% | Feb 28, 25 |
| 19 | iShares Biotechnology ETF | 317.82K (1.20%) | 0.00 Increased by 0.00% | Nov 30, 24 |
| 20 | Fidelity Series Growth Company | 292.20K (1.10%) | -10.70K Decreased by -3.66% | May 31, 24 |