| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | RA Capital Management, LLC | 10.23M (36.91%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 2 | RTW INVESTMENTS, LLC | 5.85M (21.09%) | 0.00 Increased by 0.00% | Jun 30, 24 |
| 3 | TCG Crossover Management, LLC | 5.25M (18.94%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 4 | Suvretta Capital Management, LLC | 5.08M (18.34%) | 15.51K Increased by +0.31% | Jun 30, 25 |
| 5 | Adage Capital Partners Gp LLC | 4.59M (16.56%) | 1.59M Increased by +34.63% | Jun 30, 25 |
| 6 | BlackRock Inc | 4.38M (15.80%) | -331.67K Decreased by -7.57% | Jun 30, 25 |
| 7 | Nantahala Capital Management, LLC | 4.29M (15.47%) | -534.39K Decreased by -12.46% | Jun 30, 25 |
| 8 | Vanguard Group Inc | 3.15M (11.35%) | -73.94K Decreased by -2.35% | Jun 30, 25 |
| 9 | COWEN AND COMPANY, LLC | 2.96M (10.70%) | -749.81K Decreased by -25.30% | Jun 30, 24 |
| 10 | TRV GP IV, LLC | 2.34M (8.45%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 11 | FMR Inc | 1.72M (6.22%) | -3.61M Decreased by -209.16% | Sep 30, 24 |
| 12 | Morgan Stanley - Brokerage Accounts | 1.53M (5.53%) | 1.18M Increased by +77.11% | Dec 31, 24 |
| 13 | MPM Oncology Impact Management LP | 1.44M (5.21%) | 307.74K Increased by +21.30% | Jun 30, 24 |
| 14 | Jefferies Financial Group Inc | 1.43M (5.17%) | 281.59K Increased by +19.65% | Jun 30, 24 |
| 15 | Dimensional Fund Advisors, Inc. | 1.37M (4.95%) | -34.41K Decreased by -2.51% | Jun 30, 25 |
| 16 | Balyasny Asset Management LLC | 1.34M (4.83%) | 1.34M Increased by +100.00% | Jun 30, 25 |
| 17 | State Street Corp | 1.22M (4.40%) | -34.07K Decreased by -2.80% | Jun 30, 25 |
| 18 | Logos Global Management LP | 1.20M (4.33%) | 1.20M Increased by +100.00% | Dec 31, 23 |
| 19 | Geode Capital Management, LLC | 1.19M (4.31%) | -38.24K Decreased by -3.20% | Jun 30, 25 |
| 20 | D. E. Shaw & Co LP | 1.18M (4.25%) | 596.05K Increased by +50.65% | Jun 30, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard US Total Market Shares ETF | 1.85M (6.68%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 2 | Vanguard Total Stock Mkt Idx Inv | 1.81M (6.54%) | -40.15K Decreased by -2.22% | Jul 31, 25 |
| 3 | Fidelity Growth Compy Commingled Pl O | 1.81M (6.54%) | 0.00 Increased by 0.00% | May 31, 24 |
| 4 | Fidelity® Select Biotechnology | 1.56M (5.62%) | -136.10K Decreased by -8.73% | Nov 30, 23 |
| 5 | iShares Russell 2000 ETF | 1.31M (4.74%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 6 | Fidelity Select Biotechnology | 1.26M (4.53%) | 0.00 Increased by 0.00% | May 31, 24 |
| 7 | Fidelity® Growth Company | 869.67K (3.14%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 8 | Select Pharmaceuticals Port | 762.00K (2.75%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 9 | Fidelity Select Pharmaceuticals Port | 683.60K (2.47%) | 0.00 Increased by 0.00% | May 31, 24 |
| 10 | Fidelity Small Cap Index | 537.16K (1.94%) | -11.34K Decreased by -2.11% | Jun 30, 25 |
| 11 | Fidelity Growth Compy Commingled Pl S | 494.64K (1.78%) | -295.57K Decreased by -59.75% | Nov 30, 24 |
| 12 | Fidelity® Growth Company K6 | 471.79K (1.70%) | -51.29K Decreased by -10.87% | Nov 30, 23 |
| 13 | Simplify Propel Opportunities ETF | 465.00K (1.68%) | 0.00 Increased by 0.00% | Jun 30, 24 |
| 14 | Vanguard Institutional Extnd Mkt Idx Tr | 459.61K (1.66%) | -200.05K Decreased by -43.53% | Jul 31, 25 |
| 15 | SPDR® S&P Pharmaceuticals ETF | 436.70K (1.58%) | 0.00 Increased by 0.00% | Nov 30, 24 |
| 16 | iShares Russell 2000 Value ETF | 426.83K (1.54%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 17 | State St Russell Sm/Mid Cp® Indx NL Cl C | 368.38K (1.33%) | 0.00 Increased by 0.00% | Apr 30, 25 |
| 18 | State St Russell Sm/Mid Cp® Indx SL Cl I | 368.38K (1.33%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 19 | Invesco Dorsey Wright SmallCap Momt ETF | 359.65K (1.30%) | 466.00 Increased by +0.13% | Aug 29, 25 |
| 20 | Fidelity® Series Growth Company | 356.20K (1.29%) | 0.00 Increased by 0.00% | Nov 30, 23 |