| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Suvretta Capital Management, LLC | 6.56M (13.68%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 2 | RA Capital Management, LLC | 6.05M (12.62%) | -4.18M Decreased by -68.97% | Dec 31, 25 |
| 3 | RTW INVESTMENTS, LLC | 5.85M (12.19%) | 0.00 Increased by 0.00% | Jun 30, 24 |
| 4 | TCG Crossover Management, LLC | 5.25M (10.94%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 5 | Nantahala Capital Management, LLC | 4.29M (8.95%) | -377.44K Decreased by -8.79% | Dec 31, 25 |
| 6 | BlackRock Inc | 4.26M (8.89%) | 557.01K Increased by +13.06% | Dec 31, 25 |
| 7 | Vanguard Group Inc | 3.56M (7.42%) | 560.09K Increased by +15.73% | Dec 31, 25 |
| 8 | BRAIDWELL LP | 3.06M (6.38%) | 2.84M Increased by +92.83% | Dec 31, 25 |
| 9 | COWEN AND COMPANY, LLC | 2.96M (6.18%) | -749.81K Decreased by -25.30% | Jun 30, 24 |
| 10 | Point72 Asset Management, L.P. | 2.40M (5.00%) | 2.40M Increased by +100.00% | Dec 31, 25 |
| 11 | TRV GP IV, LLC | 2.34M (4.88%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 12 | First Turn Management LLC | 2.26M (4.70%) | 363.43K Increased by +16.11% | Mar 31, 26 |
| 13 | Aberdeen Group PLC | 2.21M (4.61%) | 957.93K Increased by +43.31% | Mar 31, 26 |
| 14 | Siren, L.L.C. | 1.95M (4.07%) | 1.95M Increased by +100.00% | Dec 31, 25 |
| 15 | D. E. Shaw & Co LP | 1.91M (3.99%) | 464.33K Increased by +24.26% | Dec 31, 25 |
| 16 | GSK PLC | 1.79M (3.72%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 17 | FMR Inc | 1.72M (3.59%) | -3.61M Decreased by -209.16% | Sep 30, 24 |
| 18 | Adage Capital Partners Gp LLC | 1.70M (3.54%) | -732.00K Decreased by -43.06% | Dec 31, 25 |
| 19 | Morgan Stanley - Brokerage Accounts | 1.53M (3.19%) | 1.18M Increased by +77.11% | Dec 31, 24 |
| 20 | MPM Oncology Impact Management LP | 1.44M (3.01%) | 307.74K Increased by +21.30% | Jun 30, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 2.07M (4.32%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 2 | Vanguard US Total Market Shares ETF | 1.85M (3.86%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 3 | Fidelity Growth Compy Commingled Pl O | 1.81M (3.78%) | 0.00 Increased by 0.00% | May 31, 24 |
| 4 | Fidelity® Select Biotechnology | 1.56M (3.25%) | -136.10K Decreased by -8.73% | Nov 30, 23 |
| 5 | abrdn Life Sciences Investors | 1.52M (3.17%) | 0.00 Increased by 0.00% | Apr 30, 26 |
| 6 | iShares Russell 2000 ETF | 1.42M (2.95%) | 11.94K Increased by +0.84% | Apr 30, 26 |
| 7 | Fidelity Select Biotechnology | 1.26M (2.62%) | 0.00 Increased by 0.00% | May 31, 24 |
| 8 | Fidelity® Growth Company | 869.67K (1.81%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 9 | Select Pharmaceuticals Port | 762.00K (1.59%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 10 | abrdn Healthcare Investors | 693.45K (1.45%) | 0.00 Increased by 0.00% | Apr 30, 26 |
| 11 | Fidelity Select Pharmaceuticals Port | 683.60K (1.43%) | 0.00 Increased by 0.00% | May 31, 24 |
| 12 | Vanguard Institutional Extnd Mkt Idx Tr | 549.11K (1.14%) | 20.57K Increased by +3.75% | Mar 31, 26 |
| 13 | Fidelity Growth Compy Commingled Pl S | 494.64K (1.03%) | -295.57K Decreased by -59.75% | Nov 30, 24 |
| 14 | Fidelity® Growth Company K6 | 471.79K (0.98%) | -51.29K Decreased by -10.87% | Nov 30, 23 |
| 15 | Simplify Propel Opportunities ETF | 465.00K (0.97%) | 0.00 Increased by 0.00% | Jun 30, 24 |
| 16 | iShares Russell 2000 Value ETF | 463.48K (0.97%) | 2.50K Increased by +0.54% | Apr 30, 26 |
| 17 | SPDR® S&P Pharmaceuticals ETF | 436.70K (0.91%) | 0.00 Increased by 0.00% | Nov 30, 24 |
| 18 | iShares Biotechnology ETF | 423.36K (0.88%) | 2.68K Increased by +0.63% | Apr 30, 26 |
| 19 | Fidelity Small Cap Index | 422.20K (0.88%) | 4.13K Increased by +0.98% | Feb 28, 26 |
| 20 | State Street® SPDR® S&P® PhrmctlsETF | 396.77K (0.83%) | 0.00 Increased by 0.00% | Apr 30, 26 |