| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Bvf Inc | 4.63M (12.97%) | 68.00K Increased by +1.47% | Jun 30, 25 |
| 2 | RA Capital Management, LLC | 4.56M (12.78%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 3 | Goldman Sachs Group Inc | 4.16M (11.65%) | -9.13K Decreased by -0.22% | Jun 30, 25 |
| 4 | BlackRock Inc | 4.01M (11.23%) | -536.40K Decreased by -13.37% | Jun 30, 25 |
| 5 | Viking Global Investors LP | 2.93M (8.22%) | 0.00 Increased by 0.00% | Jun 30, 24 |
| 6 | Vanguard Group Inc | 2.74M (7.66%) | -20.82K Decreased by -0.76% | Jun 30, 25 |
| 7 | State Street Corporation | 2.18M (6.10%) | 654.24K Increased by +30.04% | Mar 31, 24 |
| 8 | Novo A/S | 2.00M (5.60%) | 50.00K Increased by +2.50% | Jun 30, 25 |
| 9 | HHG PLC | 1.75M (4.91%) | -137.53K Decreased by -7.84% | Jun 30, 25 |
| 10 | Federated Hermes Inc | 1.67M (4.67%) | 417.16K Increased by +25.02% | Jun 30, 25 |
| 11 | Millennium Management LLC | 1.48M (4.16%) | -150.26K Decreased by -10.13% | Jun 30, 25 |
| 12 | BRAIDWELL LP | 1.23M (3.43%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 13 | Casdin Capital, LLC | 1.15M (3.22%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 14 | FMR Inc | 1.02M (2.85%) | 47.34K Increased by +4.66% | Jun 30, 24 |
| 15 | Redmile Group, LLC | 997.24K (2.79%) | -199.68K Decreased by -20.02% | Mar 31, 25 |
| 16 | State Street Corp | 961.96K (2.69%) | -65.99K Decreased by -6.86% | Jun 30, 25 |
| 17 | Morgan Stanley - Brokerage Accounts | 924.68K (2.59%) | -852.07K Decreased by -92.15% | Jun 30, 25 |
| 18 | Geode Capital Management, LLC | 918.53K (2.57%) | -44.74K Decreased by -4.87% | Jun 30, 25 |
| 19 | Bank of America Corp | 897.07K (2.51%) | 198.76K Increased by +22.16% | Jun 30, 25 |
| 20 | JPMorgan Chase & Co | 888.02K (2.49%) | 1.31K Increased by +0.15% | Jun 30, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard US Total Market Shares ETF | 1.54M (4.31%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 2 | Vanguard Total Stock Mkt Idx Inv | 1.50M (4.21%) | -33.14K Decreased by -2.20% | Jul 31, 25 |
| 3 | Federated Hermes MDT SCC Institutional | 1.12M (3.14%) | 253.62K Increased by +22.64% | Jun 30, 25 |
| 4 | Federated Hermes MDT Small Cap Core IS | 1.12M (3.14%) | 253.62K Increased by +22.64% | Jun 30, 25 |
| 5 | iShares Russell 2000 ETF | 1.00M (2.80%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 6 | SPDR® S&P Biotech ETF | 990.08K (2.77%) | -30.06K Decreased by -3.04% | Nov 27, 24 |
| 7 | Janus Henderson Global Life Sciences | 835.18K (2.34%) | -116.90K Decreased by -14.00% | Jun 30, 25 |
| 8 | Janus Henderson Global Life Sciences D | 835.18K (2.34%) | -3.02K Decreased by -0.36% | Jun 30, 25 |
| 9 | Polar Capital Healthcare Opports Inc | 790.16K (2.21%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 10 | Polar Capital Biotech S Inc | 750.00K (2.10%) | 0.00 Increased by 0.00% | Jun 30, 24 |
| 11 | Janus Selection Global Life Science AUSD | 744.60K (2.09%) | -46.09K Decreased by -6.19% | Jun 30, 24 |
| 12 | Janus Global Life Science AUSD | 717.92K (2.01%) | -20.50K Decreased by -2.86% | Jun 30, 25 |
| 13 | Janus Henderson Glb Life Scn I2 USD | 711.63K (1.99%) | -4.41K Decreased by -0.62% | Jul 31, 25 |
| 14 | Fidelity Growth Compy Commingled Pl O | 469.24K (1.31%) | 521.00 Increased by +0.11% | Jun 30, 24 |
| 15 | Eventide Healthcare & Life Sciences I | 422.86K (1.18%) | -458.30K Decreased by -108.38% | Sep 30, 24 |
| 16 | Fidelity Small Cap Index | 405.16K (1.13%) | -53.66K Decreased by -13.24% | Jun 30, 25 |
| 17 | Federated Hermes MDT SCG Institutional | 395.40K (1.11%) | 119.92K Increased by +30.33% | Jun 30, 25 |
| 18 | Federated Hermes MDT Small Cap Growth IS | 395.40K (1.11%) | 119.92K Increased by +30.33% | Jun 30, 25 |
| 19 | Xtrackers S&P Global Infra Swap ETF 1C | 376.50K (1.05%) | -200.60K Decreased by -53.28% | Oct 31, 24 |
| 20 | Fidelity® Small Cap Index | 376.39K (1.05%) | 8.96K Increased by +2.38% | Oct 31, 23 |