| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | HHG PLC | 5.25M (13.47%) | 611.28K Increased by +11.65% | Mar 31, 26 |
| 2 | RA Capital Management, LLC | 5.05M (12.96%) | -603.43K Decreased by -11.95% | Mar 31, 26 |
| 3 | The Goldman Sachs Group Inc | 4.21M (10.80%) | -97.47K Decreased by -2.32% | Mar 31, 26 |
| 4 | Goldman Sachs Group Inc | 4.16M (10.68%) | -9.13K Decreased by -0.22% | Jun 30, 25 |
| 5 | BlackRock Inc | 4.15M (10.64%) | 80.43K Increased by +1.94% | Mar 31, 26 |
| 6 | Novo A/S | 3.65M (9.37%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 7 | Vanguard Group Inc | 3.09M (7.94%) | 518.40K Increased by +16.76% | Dec 31, 25 |
| 8 | Viking Global Investors LP | 2.93M (7.53%) | 0.00 Increased by 0.00% | Jun 30, 24 |
| 9 | Bvf Inc | 2.88M (7.39%) | -1.75M Decreased by -60.78% | Mar 31, 26 |
| 10 | State Street Corp | 2.71M (6.95%) | 19.00K Increased by +0.70% | Mar 31, 26 |
| 11 | Vanguard Capital Management, LLC | 2.20M (5.64%) | 2.20M Increased by +100.00% | Mar 31, 26 |
| 12 | State Street Corporation | 2.18M (5.59%) | 654.24K Increased by +30.04% | Mar 31, 24 |
| 13 | Armistice Capital, LLC | 2.00M (5.13%) | 64.00K Increased by +3.20% | Mar 31, 26 |
| 14 | Adage Capital Partners Gp LLC | 1.61M (4.12%) | 370.00K Increased by +23.05% | Mar 31, 26 |
| 15 | Point72 Asset Management, L.P. | 1.54M (3.95%) | 1.54M Increased by +100.00% | Dec 31, 25 |
| 16 | Federated Hermes Inc | 1.43M (3.68%) | -177.22K Decreased by -12.37% | Mar 31, 26 |
| 17 | Trails Edge Capital Partners, LP | 1.30M (3.35%) | 1.30M Increased by +100.00% | Mar 31, 26 |
| 18 | BRAIDWELL LP | 1.23M (3.15%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 19 | Casdin Capital, LLC | 1.15M (2.95%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 20 | Millennium Management LLC | 1.15M (2.95%) | -334.32K Decreased by -29.09% | Sep 30, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 1.71M (4.38%) | 0.00 Increased by 0.00% | Apr 30, 26 |
| 2 | Vanguard US Total Market Shares ETF | 1.54M (3.95%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 3 | State Street® SPDR® S&P® Biotech ETF | 1.47M (3.77%) | -9.13K Decreased by -0.62% | May 31, 26 |
| 4 | iShares Russell 2000 ETF | 1.07M (2.74%) | 9.83K Increased by +0.92% | May 29, 26 |
| 5 | SPDR® S&P Biotech ETF | 990.08K (2.54%) | -30.06K Decreased by -3.04% | Nov 27, 24 |
| 6 | Janus Henderson Gbl Life Sciences Divers | 851.19K (2.19%) | 851.19K Increased by +100.00% | Sep 30, 25 |
| 7 | Janus Henderson Global Life Sciences | 843.75K (2.17%) | 1.23K Increased by +0.15% | Mar 31, 26 |
| 8 | Janus Henderson Global Life Sciences D | 843.75K (2.17%) | 3.59K Increased by +0.43% | Mar 31, 26 |
| 9 | Polar Capital Healthcare Opports Inc | 790.16K (2.03%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 10 | Janus Global Life Science AUSD | 782.98K (2.01%) | 38.58K Increased by +4.93% | Mar 31, 26 |
| 11 | Janus Henderson Glb Life Scn I2 USD | 780.76K (2.00%) | -2.22K Decreased by -0.28% | Apr 30, 26 |
| 12 | Polar Capital Biotech S Inc | 750.00K (1.93%) | 0.00 Increased by 0.00% | Jun 30, 24 |
| 13 | Janus Selection Global Life Science AUSD | 744.60K (1.91%) | -46.09K Decreased by -6.19% | Jun 30, 24 |
| 14 | Janus Henderson Hrzn Biotec E2 USD | 727.25K (1.87%) | 78.47K Increased by +10.79% | Mar 31, 26 |
| 15 | Federated Hermes MDT SCC Institutional | 702.45K (1.80%) | -49.45K Decreased by -7.04% | Mar 31, 26 |
| 16 | Federated Hermes MDT Small Cap Core IS | 702.45K (1.80%) | -49.45K Decreased by -7.04% | Mar 31, 26 |
| 17 | Fidelity Growth Compy Commingled Pl O | 469.24K (1.20%) | 521.00 Increased by +0.11% | Jun 30, 24 |
| 18 | Vanguard Institutional Extnd Mkt Idx Tr | 444.96K (1.14%) | 2.97K Increased by +0.67% | Apr 30, 26 |
| 19 | Fidelity Small Cap Index | 433.46K (1.11%) | 40.49K Increased by +9.34% | Mar 31, 26 |
| 20 | Eventide Healthcare & Life Sciences I | 422.86K (1.09%) | -458.30K Decreased by -108.38% | Sep 30, 24 |