| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Bvf Inc | 7.38M (21.56%) | 3.46M Increased by +46.87% | Sep 30, 24 |
| 2 | RA Capital Management, LLC | 5.10M (14.89%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 3 | BlackRock Inc | 4.90M (14.30%) | 612.35K Increased by +12.50% | Jun 30, 24 |
| 4 | VR Adviser, LLC | 4.40M (12.85%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 5 | Deep Track Capital, LP | 4.10M (11.97%) | 35.05K Increased by +0.86% | Sep 30, 24 |
| 6 | Goldman Sachs Group Inc | 3.59M (10.49%) | -543.22K Decreased by -15.13% | Sep 30, 24 |
| 7 | HHG PLC | 3.14M (9.16%) | -59.67K Decreased by -1.90% | Sep 30, 24 |
| 8 | Viking Global Investors LP | 2.93M (8.57%) | 0.00 Increased by 0.00% | Jun 30, 24 |
| 9 | Vanguard Group Inc | 2.77M (8.08%) | 239.54K Increased by +8.65% | Sep 30, 24 |
| 10 | State Street Corporation | 2.18M (6.36%) | 654.24K Increased by +30.04% | Mar 31, 24 |
| 11 | State Street Corp | 2.12M (6.18%) | 37.23K Increased by +1.76% | Sep 30, 24 |
| 12 | Morgan Stanley - Brokerage Accounts | 1.70M (4.97%) | -1.22M Decreased by -71.56% | Sep 30, 24 |
| 13 | Assenagon Asset Management SA | 1.54M (4.51%) | 1.09M Increased by +70.44% | Sep 30, 24 |
| 14 | Novo A/S | 1.50M (4.38%) | 100.00K Increased by +6.67% | Sep 30, 24 |
| 15 | Redmile Group, LLC | 1.26M (3.69%) | 188.66K Increased by +14.95% | Sep 30, 24 |
| 16 | BRAIDWELL LP | 1.23M (3.58%) | 855.99K Increased by +69.85% | Sep 30, 24 |
| 17 | Casdin Capital, LLC | 1.15M (3.36%) | 350.00K Increased by +30.43% | Sep 30, 24 |
| 18 | Geode Capital Management, LLC | 1.04M (3.03%) | -24.35K Decreased by -2.35% | Sep 30, 24 |
| 19 | FMR Inc | 1.02M (2.97%) | 47.34K Increased by +4.66% | Jun 30, 24 |
| 20 | Eventide Asset Management, LLC | 881.16K (2.57%) | 105.04K Increased by +11.92% | Jun 30, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 1.54M (4.49%) | 0.00 Increased by 0.00% | Oct 31, 24 |
| 2 | iShares Russell 2000 ETF | 1.41M (4.11%) | -2.94K Decreased by -0.21% | Nov 27, 24 |
| 3 | Janus Henderson Global Life Sciences | 1.02M (2.97%) | -10.84K Decreased by -1.07% | Sep 30, 24 |
| 4 | Janus Henderson Global Life Sciences D | 1.02M (2.97%) | -10.13K Decreased by -1.00% | Sep 30, 24 |
| 5 | SPDR® S&P Biotech ETF | 990.08K (2.89%) | -30.06K Decreased by -3.04% | Nov 27, 24 |
| 6 | Eventide Healthcare & Life Sciences I | 881.16K (2.57%) | 105.04K Increased by +11.92% | Jun 30, 24 |
| 7 | Polar Capital Healthcare Opports Inc | 790.16K (2.31%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 8 | Janus Henderson Glb Life Scn I2 USD | 758.43K (2.22%) | 7.53K Increased by +0.99% | Oct 31, 24 |
| 9 | Janus Global Life Science AUSD | 750.90K (2.19%) | 6.30K Increased by +0.84% | Sep 30, 24 |
| 10 | Polar Capital Biotech S Inc | 750.00K (2.19%) | 0.00 Increased by 0.00% | Jun 30, 24 |
| 11 | Janus Selection Global Life Science AUSD | 744.60K (2.18%) | -46.09K Decreased by -6.19% | Jun 30, 24 |
| 12 | Vanguard Institutional Extnd Mkt Idx Tr | 587.21K (1.72%) | -1.94K Decreased by -0.33% | Oct 31, 24 |
| 13 | Fidelity Small Cap Index | 509.96K (1.49%) | -12.52K Decreased by -2.45% | Aug 31, 24 |
| 14 | Fidelity Growth Compy Commingled Pl O | 469.24K (1.37%) | 521.00 Increased by +0.11% | Jun 30, 24 |
| 15 | Xtrackers S&P Global Infra Swap ETF 1C | 376.50K (1.10%) | -200.60K Decreased by -53.28% | Oct 31, 24 |
| 16 | Fidelity® Small Cap Index | 376.39K (1.10%) | 8.96K Increased by +2.38% | Oct 31, 23 |
| 17 | MEDICAL BioHealth EUR Acc | 354.68K (1.04%) | 0.00 Increased by 0.00% | Aug 31, 24 |
| 18 | Fidelity Growth Company Fund | 351.56K (1.03%) | -1.20K Decreased by -0.34% | Jun 30, 24 |
| 19 | iShares Russell 2000 Value ETF | 347.81K (1.02%) | 0.00 Increased by 0.00% | Apr 30, 24 |
| 20 | iShares Biotechnology ETF | 302.31K (0.88%) | 307.00 Increased by +0.10% | Nov 27, 24 |