| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Redmile Group, LLC | 12.87M (12.64%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 2 | BlackRock Inc | 10.07M (9.88%) | -107.87K Decreased by -1.07% | Mar 31, 26 |
| 3 | Vanguard Group Inc | 8.97M (8.81%) | 172.86K Increased by +1.93% | Dec 31, 25 |
| 4 | Wilshire Advisors | 8.49M (8.33%) | 8.49M Increased by +100.00% | Sep 30, 25 |
| 5 | State Street Corporation | 8.04M (7.89%) | 6.17M Increased by +76.83% | Mar 31, 24 |
| 6 | Deep Track Capital, LP | 5.57M (5.47%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 7 | Boxer Capital LLC | 4.96M (4.87%) | -3.25M Decreased by -65.61% | Sep 30, 24 |
| 8 | Bellevue Group AG | 4.84M (4.75%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 9 | Vanguard Capital Management, LLC | 4.19M (4.12%) | 4.19M Increased by +100.00% | Mar 31, 26 |
| 10 | Vanguard Portfolio Management, LLC | 4.13M (4.06%) | 4.13M Increased by +100.00% | Mar 31, 26 |
| 11 | Acadian Asset Management LLC | 4.12M (4.04%) | 4.11M Increased by +99.77% | Mar 31, 26 |
| 12 | Deerfield Management Co | 3.56M (3.49%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 13 | Two Sigma Investments LLC | 3.47M (3.40%) | 1.73M Increased by +49.98% | Mar 31, 26 |
| 14 | JPMorgan Chase & Co | 3.40M (3.34%) | 1.73M Increased by +50.87% | Mar 31, 25 |
| 15 | Johnson & Johnson | 3.38M (3.32%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 16 | EcoR1 Capital, LLC | 3.05M (2.99%) | 3.05M Increased by +100.00% | Dec 31, 24 |
| 17 | AQR Capital Management LLC | 3.00M (2.95%) | 1.84M Increased by +61.29% | Mar 31, 26 |
| 18 | Renaissance Technologies Corp | 2.97M (2.92%) | 613.80K Increased by +20.63% | Mar 31, 26 |
| 19 | Geode Capital Management, LLC | 2.59M (2.54%) | 122.08K Increased by +4.71% | Mar 31, 26 |
| 20 | Suvretta Capital Management, LLC | 2.56M (2.52%) | 2.56M Increased by +100.00% | Mar 31, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | BB Biotech AG Ord | 4.84M (4.75%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 2 | Vanguard US Total Market Shares ETF | 3.05M (2.99%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 3 | Vanguard Total Stock Mkt Idx Inv | 2.97M (2.92%) | 0.00 Increased by 0.00% | Apr 30, 26 |
| 4 | iShares Russell 2000 ETF | 2.59M (2.54%) | 23.92K Increased by +0.92% | May 29, 26 |
| 5 | Vanguard Strategic Equity Inv | 2.54M (2.49%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 6 | SPDR® S&P Biotech ETF | 2.35M (2.31%) | -71.37K Decreased by -3.04% | Nov 27, 24 |
| 7 | Vanguard Explorer Inv | 1.27M (1.24%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 8 | Vanguard Institutional Extnd Mkt Idx Tr | 1.18M (1.16%) | 75.82K Increased by +6.43% | Apr 30, 26 |
| 9 | Vanguard Small Cap Index | 1.08M (1.06%) | 3.34K Increased by +0.31% | Nov 30, 23 |
| 10 | Fidelity Small Cap Index | 1.08M (1.06%) | 10.38K Increased by +0.96% | Mar 31, 26 |
| 11 | iShares Russell 2000 Value ETF | 911.21K (0.89%) | 0.00 Increased by 0.00% | May 29, 26 |
| 12 | BlackRock Advantage Small Cap Core Instl | 876.11K (0.86%) | 0.00 Increased by 0.00% | Apr 30, 26 |
| 13 | Fidelity® Small Cap Index | 812.70K (0.80%) | 13.38K Increased by +1.65% | Oct 31, 23 |
| 14 | Bruce | 789.19K (0.77%) | 60.00K Increased by +7.60% | Mar 31, 26 |
| 15 | Russell 2000 Equity Index Fund B | 758.23K (0.74%) | -345.00 Decreased by -0.05% | Dec 31, 25 |
| 16 | Biotech Growth Ord | 687.00K (0.67%) | 0.00 Increased by 0.00% | May 31, 25 |
| 17 | JPMorgan US Small Company L | 673.58K (0.66%) | -516.65K Decreased by -76.70% | Apr 30, 25 |
| 18 | Federated Hermes MDT SCC Institutional | 666.78K (0.65%) | 0.00 Increased by 0.00% | Jun 30, 24 |
| 19 | State St Russell Sm/Mid Cp® Indx NL Cl C | 638.96K (0.63%) | 0.00 Increased by 0.00% | Apr 30, 25 |
| 20 | State St Russell Sm/Mid Cp® Indx SL Cl I | 638.96K (0.63%) | 0.00 Increased by 0.00% | Apr 30, 26 |