| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Redmile Group, LLC | 12.87M (12.88%) | -296.11K Decreased by -2.30% | Dec 31, 24 |
| 2 | BlackRock Inc | 10.94M (10.95%) | 468.33K Increased by +4.28% | Dec 31, 24 |
| 3 | Vanguard Group Inc | 10.33M (10.34%) | -71.09K Decreased by -0.69% | Dec 31, 24 |
| 4 | State Street Corporation | 8.04M (8.04%) | 6.17M Increased by +76.83% | Mar 31, 24 |
| 5 | Deep Track Capital, LP | 5.57M (5.57%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 6 | Boxer Capital LLC | 4.96M (4.96%) | -3.25M Decreased by -65.61% | Sep 30, 24 |
| 7 | Bellevue Group AG | 4.84M (4.84%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 8 | Citadel Advisors Llc | 4.38M (4.38%) | 100.18K Increased by +2.29% | Dec 31, 24 |
| 9 | Deerfield Management Co | 3.56M (3.56%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 10 | Johnson & Johnson | 3.38M (3.38%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 11 | D. E. Shaw & Co LP | 3.38M (3.38%) | -700.27K Decreased by -20.73% | Sep 30, 24 |
| 12 | Baker Bros Advisors LP | 3.26M (3.26%) | 260.63K Increased by +8.00% | Dec 31, 24 |
| 13 | Woodline Partners LP | 3.07M (3.07%) | 2.06M Increased by +67.32% | Sep 30, 24 |
| 14 | EcoR1 Capital, LLC | 3.05M (3.05%) | 3.05M Increased by +100.00% | Dec 31, 24 |
| 15 | Dimensional Fund Advisors, Inc. | 2.90M (2.90%) | 279.36K Increased by +9.64% | Dec 31, 24 |
| 16 | Morgan Stanley - Brokerage Accounts | 2.82M (2.82%) | -241.24K Decreased by -8.55% | Dec 31, 24 |
| 17 | Suvretta Capital Management, LLC | 2.56M (2.56%) | 2.56M Increased by +100.00% | Mar 31, 24 |
| 18 | Holocene Advisors, LP | 2.53M (2.53%) | 2.53M Increased by +100.00% | Mar 31, 24 |
| 19 | Goldman Sachs Group Inc | 2.48M (2.48%) | -346.99K Decreased by -14.01% | Dec 31, 24 |
| 20 | Vestal Point Capital LP | 2.46M (2.47%) | 780.00K Increased by +31.64% | Dec 31, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | BB Biotech AG Ord | 4.84M (4.84%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 2 | Vanguard Total Stock Mkt Idx Inv | 3.05M (3.05%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 3 | iShares Russell 2000 ETF | 2.62M (2.62%) | -22.71K Decreased by -0.87% | Mar 31, 25 |
| 4 | Vanguard Strategic Equity Inv | 2.54M (2.54%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 5 | SPDR® S&P Biotech ETF | 2.35M (2.35%) | -71.37K Decreased by -3.04% | Nov 27, 24 |
| 6 | JPMorgan US Small Company L | 1.87M (1.87%) | 1.40M Increased by +74.93% | Feb 28, 25 |
| 7 | Vanguard Institutional Extnd Mkt Idx Tr | 1.40M (1.40%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 8 | Vanguard Explorer Inv | 1.27M (1.27%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 9 | Vanguard Small Cap Index | 1.08M (1.08%) | 3.34K Increased by +0.31% | Nov 30, 23 |
| 10 | Fidelity Small Cap Index | 973.91K (0.97%) | -18.24K Decreased by -1.87% | Jan 31, 25 |
| 11 | BlackRock Advantage Small Cap Core Instl | 955.56K (0.96%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 12 | iShares Russell 2000 Value ETF | 909.94K (0.91%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 13 | Fidelity® Small Cap Index | 812.70K (0.81%) | 13.38K Increased by +1.65% | Oct 31, 23 |
| 14 | Multi-Manager Small Cap Eq Strat Inst | 811.32K (0.81%) | 478.52K Increased by +58.98% | Feb 28, 25 |
| 15 | DFA US Targeted Value I | 746.55K (0.75%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 16 | Biotech Growth Ord | 687.00K (0.69%) | 0.00 Increased by 0.00% | Nov 30, 24 |
| 17 | Federated Hermes MDT SCC Institutional | 666.78K (0.67%) | 0.00 Increased by 0.00% | Jun 30, 24 |
| 18 | iShares Biotechnology ETF | 652.52K (0.65%) | -7.27K Decreased by -1.11% | Mar 31, 25 |
| 19 | State St Russell Sm/Mid Cp® Indx NL Cl C | 638.96K (0.64%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 20 | T. Rowe Price Health Sciences | 635.97K (0.64%) | -18.05K Decreased by -2.84% | Sep 30, 23 |