| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Redmile Group, LLC | 12.87M (12.77%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 2 | BlackRock Inc | 10.68M (10.60%) | -259.80K Decreased by -2.43% | Mar 31, 25 |
| 3 | Vanguard Group Inc | 8.77M (8.70%) | -1.54M Decreased by -17.61% | Jun 30, 25 |
| 4 | State Street Corporation | 8.04M (7.97%) | 6.17M Increased by +76.83% | Mar 31, 24 |
| 5 | Deep Track Capital, LP | 5.57M (5.53%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 6 | Boxer Capital LLC | 4.96M (4.92%) | -3.25M Decreased by -65.61% | Sep 30, 24 |
| 7 | Bellevue Group AG | 4.84M (4.80%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 8 | Citadel Advisors Llc | 4.29M (4.26%) | -93.10K Decreased by -2.17% | Mar 31, 25 |
| 9 | Deerfield Management Co | 3.56M (3.53%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 10 | JPMorgan Chase & Co | 3.40M (3.37%) | 1.73M Increased by +50.87% | Mar 31, 25 |
| 11 | Johnson & Johnson | 3.38M (3.35%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 12 | EcoR1 Capital, LLC | 3.05M (3.03%) | 3.05M Increased by +100.00% | Dec 31, 24 |
| 13 | Suvretta Capital Management, LLC | 2.56M (2.54%) | 2.56M Increased by +100.00% | Mar 31, 24 |
| 14 | Holocene Advisors, LP | 2.53M (2.51%) | 2.53M Increased by +100.00% | Mar 31, 24 |
| 15 | Vestal Point Capital LP | 2.52M (2.50%) | 50.85K Increased by +2.02% | Mar 31, 25 |
| 16 | Goldman Sachs Group Inc | 2.51M (2.49%) | 52.70K Increased by +2.10% | Jun 30, 25 |
| 17 | Baker Bros Advisors LP | 2.49M (2.47%) | -773.38K Decreased by -31.12% | Jun 30, 25 |
| 18 | Acadian Asset Management LLC | 2.47M (2.45%) | 2.38M Increased by +96.37% | Mar 31, 25 |
| 19 | Dimensional Fund Advisors, Inc. | 2.44M (2.42%) | -153.83K Decreased by -6.31% | Jun 30, 25 |
| 20 | Assenagon Asset Management SA | 2.43M (2.41%) | -140.50K Decreased by -5.77% | Sep 30, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | BB Biotech AG Ord | 4.84M (4.80%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 2 | Vanguard US Total Market Shares ETF | 3.05M (3.03%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 3 | Vanguard Total Stock Mkt Idx Inv | 2.98M (2.96%) | -65.80K Decreased by -2.21% | Jul 31, 25 |
| 4 | Vanguard Strategic Equity Inv | 2.54M (2.52%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 5 | iShares Russell 2000 ETF | 2.54M (2.52%) | -48.30K Decreased by -1.90% | Jul 31, 25 |
| 6 | SPDR® S&P Biotech ETF | 2.35M (2.33%) | -71.37K Decreased by -3.04% | Nov 27, 24 |
| 7 | Vanguard Explorer Inv | 1.27M (1.26%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 8 | Vanguard Small Cap Index | 1.08M (1.07%) | 3.34K Increased by +0.31% | Nov 30, 23 |
| 9 | Fidelity Small Cap Index | 1.03M (1.02%) | -7.96K Decreased by -0.77% | May 31, 25 |
| 10 | Vanguard Institutional Extnd Mkt Idx Tr | 964.45K (0.96%) | -439.47K Decreased by -45.57% | Jul 31, 25 |
| 11 | BlackRock Advantage Small Cap Core Instl | 945.76K (0.94%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 12 | iShares Russell 2000 Value ETF | 937.66K (0.93%) | 696.00 Increased by +0.07% | Jul 31, 25 |
| 13 | Fidelity® Small Cap Index | 812.70K (0.81%) | 13.38K Increased by +1.65% | Oct 31, 23 |
| 14 | DFA US Targeted Value I | 703.91K (0.70%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 15 | Biotech Growth Ord | 687.00K (0.68%) | 0.00 Increased by 0.00% | Apr 30, 25 |
| 16 | JPMorgan US Small Company L | 673.58K (0.67%) | -516.65K Decreased by -76.70% | Apr 30, 25 |
| 17 | Federated Hermes MDT SCC Institutional | 666.78K (0.66%) | 0.00 Increased by 0.00% | Jun 30, 24 |
| 18 | iShares Biotechnology ETF | 651.61K (0.65%) | 5.57K Increased by +0.86% | Jul 31, 25 |
| 19 | State St Russell Sm/Mid Cp® Indx NL Cl C | 638.96K (0.63%) | 0.00 Increased by 0.00% | Apr 30, 25 |
| 20 | State St Russell Sm/Mid Cp® Indx SL Cl I | 638.96K (0.63%) | 0.00 Increased by 0.00% | Jul 31, 25 |