| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Orbimed Advisors, LLC | 15.52M (23.12%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 2 | RA Capital Management, LLC | 10.43M (15.54%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 3 | Paradigm Biocapital Advisors LP | 7.37M (10.97%) | 823.83K Increased by +11.19% | Mar 31, 26 |
| 4 | Baker Bros Advisors LP | 6.58M (9.80%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 5 | BlackRock Inc | 6.47M (9.64%) | -157.59K Decreased by -2.43% | Mar 31, 26 |
| 6 | HHG PLC | 5.92M (8.81%) | 1.35M Increased by +22.80% | Mar 31, 26 |
| 7 | Novo A/S | 5.35M (7.97%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 8 | Vanguard Group Inc | 4.87M (7.26%) | 67.68K Increased by +1.39% | Dec 31, 25 |
| 9 | FMR Inc | 4.78M (7.12%) | -1.59M Decreased by -33.16% | Jun 30, 24 |
| 10 | Driehaus Capital Management LLC | 4.48M (6.67%) | 286.75K Increased by +6.40% | Mar 31, 26 |
| 11 | Siren, L.L.C. | 4.43M (6.60%) | -99.73K Decreased by -2.25% | Mar 31, 26 |
| 12 | Perceptive Advisors LLC | 4.42M (6.59%) | -34.00K Decreased by -0.77% | Mar 31, 26 |
| 13 | Vanguard Capital Management, LLC | 3.79M (5.64%) | 3.79M Increased by +100.00% | Mar 31, 26 |
| 14 | Cormorant Asset Management, LLC | 3.26M (4.86%) | -25.00K Decreased by -0.77% | Mar 31, 26 |
| 15 | Citadel Advisors Llc | 2.35M (3.50%) | -418.26K Decreased by -17.80% | Jun 30, 24 |
| 16 | BRAIDWELL LP | 2.35M (3.50%) | -2.86M Decreased by -121.97% | Mar 31, 26 |
| 17 | Morgan Stanley - Brokerage Accounts | 2.25M (3.35%) | -664.85K Decreased by -29.60% | Mar 31, 26 |
| 18 | TCG Crossover Management, LLC | 2.11M (3.15%) | -159.74K Decreased by -7.56% | Sep 30, 24 |
| 19 | Deerfield Management Co | 2.07M (3.08%) | -11.19K Decreased by -0.54% | Jun 30, 25 |
| 20 | VR Adviser, LLC | 1.82M (2.71%) | 0.00 Increased by 0.00% | Jun 30, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 2.90M (4.32%) | 33.97K Increased by +1.17% | Apr 30, 26 |
| 2 | BB Biotech AG Ord | 2.78M (4.14%) | 0.00 Increased by 0.00% | Sep 30, 25 |
| 3 | Vanguard US Total Market Shares ETF | 2.54M (3.78%) | -5.23K Decreased by -0.21% | Sep 30, 24 |
| 4 | Strategic Advisers Fidelity US TtlStk | 1.70M (2.53%) | 1.70M Increased by +100.00% | Apr 30, 26 |
| 5 | iShares Russell 2000 ETF | 1.62M (2.41%) | 14.92K Increased by +0.92% | May 29, 26 |
| 6 | Fidelity® Small Cap Growth | 1.34M (2.00%) | -1.63K Decreased by -0.12% | Oct 31, 23 |
| 7 | Fidelity® Series Small Cap Opps | 1.27M (1.90%) | 0.00 Increased by 0.00% | Oct 31, 23 |
| 8 | Fidelity Small Cap Growth | 983.35K (1.47%) | -284.60K Decreased by -28.94% | Jul 31, 24 |
| 9 | Polar Capital Biotech S Inc | 975.00K (1.45%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 10 | Artisan International Small-Mid Investor | 914.19K (1.36%) | 281.23K Increased by +30.76% | Jun 30, 25 |
| 11 | Artisan Non-U.S. Small-Mid Growth Comp | 914.19K (1.36%) | 281.23K Increased by +30.76% | Jun 30, 25 |
| 12 | American Century Small Cap Growth Inv | 856.21K (1.28%) | -17.10K Decreased by -2.00% | Mar 31, 26 |
| 13 | American Century U.S. Small Cap Growth | 856.21K (1.28%) | -17.10K Decreased by -2.00% | Mar 31, 26 |
| 14 | Vanguard Institutional Extnd Mkt Idx Tr | 836.47K (1.25%) | 9.86K Increased by +1.18% | Apr 30, 26 |
| 15 | Victory Pioneer Select Mid Cap Growth A | 723.18K (1.08%) | 57.01K Increased by +7.88% | Mar 31, 26 |
| 16 | Fidelity Select Biotechnology | 699.42K (1.04%) | -96.40K Decreased by -13.78% | Apr 30, 26 |
| 17 | Fidelity® Stock Selector Small Cap | 673.85K (1.00%) | 0.00 Increased by 0.00% | Oct 31, 23 |
| 18 | Janus Henderson Hrzn Biotec E2 USD | 665.52K (0.99%) | 87.04K Increased by +13.08% | Mar 31, 26 |
| 19 | Fidelity Small Cap Index | 661.99K (0.99%) | 962.00 Increased by +0.15% | Mar 31, 26 |
| 20 | Janus Henderson Global Life Sciences | 659.24K (0.98%) | 41.61K Increased by +6.31% | Mar 31, 26 |