| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Orbimed Advisors, LLC | 15.02M (24.01%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 2 | RA Capital Management, LLC | 8.91M (14.24%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 3 | Perceptive Advisors LLC | 6.55M (10.46%) | 3.86M Increased by +58.98% | Mar 31, 25 |
| 4 | BlackRock Inc | 6.49M (10.36%) | 5.99K Increased by +0.09% | Mar 31, 25 |
| 5 | Baker Bros Advisors LP | 6.16M (9.84%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 6 | Novo A/S | 5.35M (8.55%) | 350.00K Increased by +6.54% | Mar 31, 25 |
| 7 | HHG PLC | 5.28M (8.44%) | 298.21K Increased by +5.65% | Mar 31, 25 |
| 8 | FMR Inc | 4.78M (7.64%) | -1.59M Decreased by -33.16% | Jun 30, 24 |
| 9 | Paradigm Biocapital Advisors LP | 4.39M (7.02%) | -99.37K Decreased by -2.26% | Mar 31, 25 |
| 10 | Vanguard Group Inc | 4.29M (6.86%) | -172.44K Decreased by -4.02% | Mar 31, 25 |
| 11 | Cormorant Asset Management, LLC | 4.10M (6.56%) | 695.46K Increased by +16.95% | Mar 31, 25 |
| 12 | BRAIDWELL LP | 2.46M (3.93%) | 126.61K Increased by +5.15% | Mar 31, 25 |
| 13 | Citadel Advisors Llc | 2.35M (3.75%) | -418.26K Decreased by -17.80% | Jun 30, 24 |
| 14 | TCG Crossover Management, LLC | 2.11M (3.38%) | -159.74K Decreased by -7.56% | Sep 30, 24 |
| 15 | Deerfield Management Co | 2.08M (3.32%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 16 | First Light Asset Management, LLC | 1.85M (2.96%) | 1.07M Increased by +57.86% | Mar 31, 25 |
| 17 | VR Adviser, LLC | 1.82M (2.91%) | 0.00 Increased by 0.00% | Jun 30, 24 |
| 18 | State Street Corp | 1.72M (2.75%) | 2.18K Increased by +0.13% | Mar 31, 25 |
| 19 | Siren, L.L.C. | 1.70M (2.71%) | 962.10K Increased by +56.71% | Mar 31, 25 |
| 20 | Geode Capital Management, LLC | 1.66M (2.65%) | 55.09K Increased by +3.33% | Mar 31, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 2.89M (4.61%) | 744.00 Increased by +0.03% | May 31, 25 |
| 2 | Vanguard US Total Market Shares ETF | 2.54M (4.05%) | -5.23K Decreased by -0.21% | Sep 30, 24 |
| 3 | iShares Russell 2000 ETF | 1.85M (2.96%) | 0.00 Increased by 0.00% | May 31, 25 |
| 4 | BB Biotech AG Ord | 1.43M (2.28%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 5 | Fidelity® Small Cap Growth | 1.34M (2.15%) | -1.63K Decreased by -0.12% | Oct 31, 23 |
| 6 | Fidelity® Series Small Cap Opps | 1.27M (2.04%) | 0.00 Increased by 0.00% | Oct 31, 23 |
| 7 | Vanguard Institutional Extnd Mkt Idx Tr | 1.07M (1.72%) | 7.76K Increased by +0.72% | May 31, 25 |
| 8 | Polar Capital Biotech S Inc | 1.00M (1.60%) | 750.00K Increased by +75.00% | Apr 30, 25 |
| 9 | Fidelity Small Cap Growth | 983.35K (1.57%) | -284.60K Decreased by -28.94% | Jul 31, 24 |
| 10 | Janus Henderson Global Life Sciences D | 851.17K (1.36%) | 166.61K Increased by +19.57% | Apr 30, 25 |
| 11 | Fidelity Small Cap Index | 735.30K (1.18%) | 15.29K Increased by +2.08% | Mar 31, 25 |
| 12 | Janus Henderson Global Life Sciences | 684.56K (1.09%) | -19.92K Decreased by -2.91% | Mar 31, 25 |
| 13 | Janus Henderson Glb Life Scn I2 USD | 682.99K (1.09%) | 129.37K Increased by +18.94% | Apr 30, 25 |
| 14 | Fidelity® Stock Selector Small Cap | 673.85K (1.08%) | 0.00 Increased by 0.00% | Oct 31, 23 |
| 15 | iShares Russell 2000 Growth ETF | 640.84K (1.02%) | 0.00 Increased by 0.00% | May 31, 25 |
| 16 | Artisan International Small-Mid Investor | 632.96K (1.01%) | -76.45K Decreased by -12.08% | Mar 31, 25 |
| 17 | Artisan Non-U.S. Small-Mid Growth Comp | 632.96K (1.01%) | -76.45K Decreased by -12.08% | Mar 31, 25 |
| 18 | American Century Small Cap Growth Inv | 609.49K (0.97%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 19 | American Century U.S. Small Cap Growth | 609.49K (0.97%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 20 | Eventide Healthcare & Life Sciences I | 568.31K (0.91%) | 568.31K Increased by +100.00% | Mar 31, 25 |