| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Orbimed Advisors, LLC | 15.02M (24.82%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 2 | RA Capital Management, LLC | 9.90M (16.36%) | 993.54K Increased by +10.03% | Jun 30, 25 |
| 3 | Baker Bros Advisors LP | 7.31M (12.07%) | 1.15M Increased by +15.74% | Jun 30, 25 |
| 4 | BlackRock Inc | 6.49M (10.71%) | 5.99K Increased by +0.09% | Mar 31, 25 |
| 5 | Paradigm Biocapital Advisors LP | 6.14M (10.15%) | 1.75M Increased by +28.45% | Jun 30, 25 |
| 6 | HHG PLC | 5.50M (9.09%) | 221.19K Increased by +4.02% | Jun 30, 25 |
| 7 | Novo A/S | 5.35M (8.84%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 8 | BRAIDWELL LP | 5.21M (8.61%) | 2.75M Increased by +52.81% | Jun 30, 25 |
| 9 | Vanguard Group Inc | 4.84M (8.00%) | 547.10K Increased by +11.30% | Jun 30, 25 |
| 10 | FMR Inc | 4.78M (7.90%) | -1.59M Decreased by -33.16% | Jun 30, 24 |
| 11 | Perceptive Advisors LLC | 4.64M (7.67%) | -1.91M Decreased by -41.11% | Jun 30, 25 |
| 12 | Cormorant Asset Management, LLC | 4.25M (7.02%) | 150.00K Increased by +3.53% | Jun 30, 25 |
| 13 | Siren, L.L.C. | 3.16M (5.22%) | 1.46M Increased by +46.32% | Jun 30, 25 |
| 14 | Bellevue Group AG | 2.78M (4.59%) | 1.35M Increased by +48.53% | Jun 30, 25 |
| 15 | Citadel Advisors Llc | 2.35M (3.88%) | -418.26K Decreased by -17.80% | Jun 30, 24 |
| 16 | TCG Crossover Management, LLC | 2.11M (3.49%) | -159.74K Decreased by -7.56% | Sep 30, 24 |
| 17 | Deerfield Management Co | 2.07M (3.42%) | -11.19K Decreased by -0.54% | Jun 30, 25 |
| 18 | VR Adviser, LLC | 1.82M (3.00%) | 0.00 Increased by 0.00% | Jun 30, 24 |
| 19 | MPM Oncology Impact Management LP | 1.72M (2.84%) | 615.30K Increased by +35.76% | Jun 30, 25 |
| 20 | State Street Corp | 1.72M (2.84%) | 2.18K Increased by +0.13% | Mar 31, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 2.82M (4.66%) | -62.61K Decreased by -2.22% | Jul 31, 25 |
| 2 | Vanguard US Total Market Shares ETF | 2.54M (4.19%) | -5.23K Decreased by -0.21% | Sep 30, 24 |
| 3 | iShares Russell 2000 ETF | 1.76M (2.91%) | -19.66K Decreased by -1.11% | Aug 29, 25 |
| 4 | BB Biotech AG Ord | 1.43M (2.36%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 5 | Fidelity® Small Cap Growth | 1.34M (2.22%) | -1.63K Decreased by -0.12% | Oct 31, 23 |
| 6 | Fidelity® Series Small Cap Opps | 1.27M (2.10%) | 0.00 Increased by 0.00% | Oct 31, 23 |
| 7 | Fidelity Small Cap Growth | 983.35K (1.62%) | -284.60K Decreased by -28.94% | Jul 31, 24 |
| 8 | Polar Capital Biotech S Inc | 975.00K (1.61%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 9 | Artisan International Small-Mid Investor | 914.19K (1.51%) | 281.23K Increased by +30.76% | Jun 30, 25 |
| 10 | Artisan Non-U.S. Small-Mid Growth Comp | 914.19K (1.51%) | 281.23K Increased by +30.76% | Jun 30, 25 |
| 11 | Janus Henderson Global Life Sciences | 838.14K (1.38%) | 153.58K Increased by +18.32% | Jun 30, 25 |
| 12 | Janus Henderson Global Life Sciences D | 838.14K (1.38%) | -8.23K Decreased by -0.98% | Jun 30, 25 |
| 13 | Vanguard Institutional Extnd Mkt Idx Tr | 749.77K (1.24%) | -328.86K Decreased by -43.86% | Jul 31, 25 |
| 14 | Fidelity Small Cap Index | 732.11K (1.21%) | -14.05K Decreased by -1.92% | Jun 30, 25 |
| 15 | Janus Global Life Science AUSD | 690.33K (1.14%) | 136.71K Increased by +19.80% | Jun 30, 25 |
| 16 | Janus Henderson Glb Life Scn I2 USD | 683.73K (1.13%) | -4.79K Decreased by -0.70% | Jul 31, 25 |
| 17 | Fidelity® Stock Selector Small Cap | 673.85K (1.11%) | 0.00 Increased by 0.00% | Oct 31, 23 |
| 18 | iShares Russell 2000 Growth ETF | 647.14K (1.07%) | 0.00 Increased by 0.00% | Aug 29, 25 |
| 19 | American Century Small Cap Growth Inv | 609.49K (1.01%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 20 | American Century U.S. Small Cap Growth | 609.49K (1.01%) | 0.00 Increased by 0.00% | Jun 30, 25 |