| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Orbimed Advisors, LLC | 15.02M (24.01%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 2 | RA Capital Management, LLC | 8.91M (14.24%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 3 | Perceptive Advisors LLC | 6.55M (10.46%) | 3.86M Increased by +58.98% | Mar 31, 25 |
| 4 | BlackRock Inc | 6.49M (10.36%) | 5.99K Increased by +0.09% | Mar 31, 25 |
| 5 | Baker Bros Advisors LP | 6.16M (9.84%) | 315.88K Increased by +5.13% | Dec 31, 24 |
| 6 | Novo A/S | 5.35M (8.55%) | 350.00K Increased by +6.54% | Mar 31, 25 |
| 7 | HHG PLC | 5.28M (8.44%) | 298.21K Increased by +5.65% | Mar 31, 25 |
| 8 | FMR Inc | 4.78M (7.64%) | -1.59M Decreased by -33.16% | Jun 30, 24 |
| 9 | Paradigm Biocapital Advisors LP | 4.49M (7.18%) | 1.70M Increased by +37.93% | Dec 31, 24 |
| 10 | Vanguard Group Inc | 4.29M (6.86%) | -172.44K Decreased by -4.02% | Mar 31, 25 |
| 11 | Cormorant Asset Management, LLC | 3.41M (5.44%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 12 | BRAIDWELL LP | 2.46M (3.93%) | 126.61K Increased by +5.15% | Mar 31, 25 |
| 13 | Citadel Advisors Llc | 2.35M (3.75%) | -418.26K Decreased by -17.80% | Jun 30, 24 |
| 14 | TCG Crossover Management, LLC | 2.11M (3.38%) | -159.74K Decreased by -7.56% | Sep 30, 24 |
| 15 | Deerfield Management Co | 2.08M (3.32%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 16 | VR Adviser, LLC | 1.82M (2.91%) | 0.00 Increased by 0.00% | Jun 30, 24 |
| 17 | State Street Corp | 1.72M (2.75%) | 2.18K Increased by +0.13% | Mar 31, 25 |
| 18 | Goldman Sachs Group Inc | 1.62M (2.59%) | -125.10K Decreased by -7.71% | Jun 30, 24 |
| 19 | Geode Capital Management, LLC | 1.60M (2.56%) | 1.04K Increased by +0.06% | Dec 31, 24 |
| 20 | Driehaus Capital Management LLC | 1.49M (2.39%) | -459.63K Decreased by -30.77% | Dec 31, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 2.55M (4.07%) | 10.48K Increased by +0.41% | Mar 31, 25 |
| 2 | Vanguard US Total Market Shares ETF | 2.54M (4.05%) | -5.23K Decreased by -0.21% | Sep 30, 24 |
| 3 | iShares Russell 2000 ETF | 1.83M (2.93%) | 309.00 Increased by +0.02% | Apr 30, 25 |
| 4 | BB Biotech AG Ord | 1.43M (2.28%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 5 | Fidelity® Small Cap Growth | 1.34M (2.15%) | -1.63K Decreased by -0.12% | Oct 31, 23 |
| 6 | Fidelity® Series Small Cap Opps | 1.27M (2.04%) | 0.00 Increased by 0.00% | Oct 31, 23 |
| 7 | Fidelity Small Cap Growth | 983.35K (1.57%) | -284.60K Decreased by -28.94% | Jul 31, 24 |
| 8 | Vanguard Institutional Extnd Mkt Idx Tr | 915.87K (1.46%) | 22.19K Increased by +2.42% | Mar 31, 25 |
| 9 | Fidelity Small Cap Index | 720.01K (1.15%) | 4.13K Increased by +0.57% | Feb 28, 25 |
| 10 | Janus Henderson Global Life Sciences | 704.48K (1.13%) | 121.00K Increased by +17.18% | Dec 31, 24 |
| 11 | Janus Henderson Global Life Sciences D | 684.56K (1.09%) | -2.53K Decreased by -0.37% | Mar 31, 25 |
| 12 | Fidelity® Stock Selector Small Cap | 673.85K (1.08%) | 0.00 Increased by 0.00% | Oct 31, 23 |
| 13 | iShares Russell 2000 Growth ETF | 654.67K (1.05%) | 0.00 Increased by 0.00% | Apr 30, 25 |
| 14 | Artisan International Small-Mid Investor | 632.96K (1.01%) | -76.45K Decreased by -12.08% | Mar 31, 25 |
| 15 | Artisan Non-U.S. Small-Mid Growth Comp | 632.96K (1.01%) | -76.45K Decreased by -12.08% | Mar 31, 25 |
| 16 | American Century Small Cap Growth Inv | 609.49K (0.97%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 17 | American Century U.S. Small Cap Growth | 609.49K (0.97%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 18 | Fidelity Advisor® Biotechnology I | 566.30K (0.90%) | 76.60K Increased by +13.53% | Nov 30, 23 |
| 19 | Fidelity Select Health Care | 560.00K (0.89%) | 0.00 Increased by 0.00% | Jun 30, 24 |
| 20 | Janus Global Life Science AUSD | 553.62K (0.88%) | -6.48K Decreased by -1.17% | Mar 31, 25 |