| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | HHG PLC | 20.46M (20.14%) | 3.95M Increased by +19.30% | Mar 31, 25 |
| 2 | RA Capital Management, LLC | 19.89M (19.58%) | 5.71M Increased by +28.73% | Mar 31, 25 |
| 3 | Suvretta Capital Management, LLC | 14.34M (14.11%) | 4.13M Increased by +28.83% | Mar 31, 25 |
| 4 | BlackRock Inc | 10.08M (9.92%) | 2.19M Increased by +21.69% | Mar 31, 25 |
| 5 | Deep Track Capital, LP | 9.32M (9.17%) | 2.84M Increased by +30.46% | Mar 31, 25 |
| 6 | Vanguard Group Inc | 7.16M (7.05%) | 1.47M Increased by +20.54% | Mar 31, 25 |
| 7 | venBio Select Advisor LLC | 6.35M (6.25%) | 2.25M Increased by +35.43% | Mar 31, 25 |
| 8 | State Street Corporation | 5.54M (5.46%) | 144.23K Increased by +2.60% | Mar 31, 24 |
| 9 | Citadel Advisors Llc | 5.09M (5.01%) | 356.98K Increased by +7.02% | Mar 31, 25 |
| 10 | Bvf Inc | 4.33M (4.27%) | -2.48M Decreased by -57.17% | Dec 31, 24 |
| 11 | Pictet Asset Manangement SA | 4.20M (4.14%) | 1.20M Increased by +28.49% | Mar 31, 25 |
| 12 | State Street Corp | 4.03M (3.97%) | 1.09M Increased by +26.92% | Mar 31, 25 |
| 13 | Westfield Capital Management Company, L.P. | 3.89M (3.83%) | 7.95K Increased by +0.20% | Mar 31, 25 |
| 14 | Holocene Advisors, LP | 3.45M (3.40%) | 1.21M Increased by +35.21% | Mar 31, 24 |
| 15 | Westfield Capital Management Company, LP | 3.01M (2.96%) | 686.67K Increased by +22.84% | Sep 30, 24 |
| 16 | Geode Capital Management, LLC | 2.90M (2.85%) | 690.37K Increased by +23.82% | Mar 31, 25 |
| 17 | Logos Global Management LP | 2.50M (2.46%) | 2.50M Increased by +100.00% | Mar 31, 25 |
| 18 | Polar Capital Holdings PLC | 2.50M (2.46%) | 2.50M Increased by +100.00% | Mar 31, 25 |
| 19 | Assenagon Asset Management SA | 2.17M (2.14%) | 1.74M Increased by +80.25% | Jun 30, 25 |
| 20 | RTW INVESTMENTS, LLC | 1.97M (1.94%) | -5.51M Decreased by -280.07% | Mar 31, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 4.81M (4.73%) | 806.70K Increased by +16.79% | Jun 30, 25 |
| 2 | iShares Russell 2000 ETF | 2.99M (2.95%) | -48.41K Decreased by -1.62% | Jul 30, 25 |
| 3 | Janus Henderson Global Life Sciences D | 2.95M (2.90%) | -8.38K Decreased by -0.28% | May 31, 25 |
| 4 | Janus Henderson Global Life Sciences | 2.92M (2.87%) | -50.20K Decreased by -1.72% | Jun 30, 25 |
| 5 | Vanguard US Total Market Shares ETF | 2.65M (2.60%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 6 | Polar Capital Biotech S Inc | 2.48M (2.44%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 7 | Janus Global Life Science AUSD | 2.42M (2.38%) | 225.46K Increased by +9.32% | Mar 31, 25 |
| 8 | Janus Henderson Glb Life Scn I2 USD | 2.41M (2.37%) | 27.36K Increased by +1.14% | Jun 30, 25 |
| 9 | Janus Henderson Triton D | 2.37M (2.34%) | 0.00 Increased by 0.00% | May 31, 25 |
| 10 | Janus Henderson US SMID Cap Growth | 2.35M (2.31%) | -27.66K Decreased by -1.18% | Jun 30, 25 |
| 11 | Janus Henderson US SMID Cap Growth MA | 2.35M (2.31%) | 2.35M Increased by +100.00% | Jun 30, 25 |
| 12 | Pictet-Biotech P USD | 2.27M (2.24%) | -38.73K Decreased by -1.70% | Apr 30, 25 |
| 13 | Janus Selection Global Life Science AUSD | 2.19M (2.16%) | -95.51K Decreased by -4.36% | Jun 30, 24 |
| 14 | Pictet Biotech | 2.04M (2.00%) | 2.04M Increased by +100.00% | Mar 31, 24 |
| 15 | Vanguard Institutional Extnd Mkt Idx Tr | 2.00M (1.97%) | 45.24K Increased by +2.26% | Jun 30, 25 |
| 16 | Harbor Small Cap Growth Instl | 1.55M (1.53%) | -416.08K Decreased by -26.77% | Jun 30, 25 |
| 17 | Westfield Capital Mgt Co Sm-Cap Gr Eq | 1.55M (1.53%) | -416.08K Decreased by -26.77% | Jun 30, 25 |
| 18 | Pictet-Global Megatrend Sel I USD | 1.53M (1.50%) | -14.83K Decreased by -0.97% | Apr 30, 25 |
| 19 | SPDR® S&P Biotech ETF | 1.48M (1.46%) | 36.63K Increased by +2.47% | Jul 31, 25 |
| 20 | Janus Henderson Hrzn Biotec E2 USD | 1.19M (1.17%) | 0.00 Increased by 0.00% | Jun 30, 25 |