| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | HHG PLC | 15.16M (19.73%) | 1.88M Increased by +12.42% | Sep 30, 24 |
| 2 | RA Capital Management, LLC | 14.18M (18.45%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 3 | Suvretta Capital Management, LLC | 7.99M (10.40%) | -40.20K Decreased by -0.50% | Sep 30, 24 |
| 4 | RTW INVESTMENTS, LLC | 7.38M (9.60%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 5 | BlackRock Inc | 7.02M (9.13%) | 377.59K Increased by +5.38% | Jun 30, 24 |
| 6 | Bvf Inc | 6.81M (8.87%) | -756.85K Decreased by -11.11% | Sep 30, 24 |
| 7 | State Street Corporation | 5.54M (7.21%) | 144.23K Increased by +2.60% | Mar 31, 24 |
| 8 | Vanguard Group Inc | 5.01M (6.52%) | 201.32K Increased by +4.02% | Sep 30, 24 |
| 9 | Holocene Advisors, LP | 3.45M (4.49%) | 1.21M Increased by +35.21% | Mar 31, 24 |
| 10 | State Street Corp | 3.25M (4.23%) | 7.18K Increased by +0.22% | Sep 30, 24 |
| 11 | Pictet Asset Manangement SA | 3.25M (4.23%) | -355.98K Decreased by -10.96% | Sep 30, 24 |
| 12 | Westfield Capital Management Company, LP | 3.01M (3.91%) | 686.67K Increased by +22.84% | Sep 30, 24 |
| 13 | Deep Track Capital, LP | 2.77M (3.60%) | 472.50K Increased by +17.08% | Sep 30, 24 |
| 14 | Citadel Advisors Llc | 2.56M (3.33%) | 447.64K Increased by +17.51% | Sep 30, 24 |
| 15 | Geode Capital Management, LLC | 2.07M (2.70%) | 160.36K Increased by +7.73% | Sep 30, 24 |
| 16 | Federated Hermes Inc | 1.96M (2.55%) | -167.03K Decreased by -8.51% | Dec 31, 23 |
| 17 | BRAIDWELL LP | 1.59M (2.07%) | 1.59M Increased by +100.00% | Sep 30, 23 |
| 18 | Redmile Group, LLC | 1.57M (2.04%) | -175.81K Decreased by -11.20% | Sep 30, 24 |
| 19 | Octagon Capital Advisors LP | 1.22M (1.59%) | 152.37K Increased by +12.50% | Sep 30, 23 |
| 20 | Marshall Wace Asset Management Ltd | 1.17M (1.52%) | -915.29K Decreased by -78.18% | Sep 30, 23 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Janus Henderson Global Life Sciences | 2.96M (3.85%) | -40.28K Decreased by -1.36% | Sep 30, 24 |
| 2 | Janus Henderson Global Life Sciences D | 2.96M (3.85%) | -38.21K Decreased by -1.29% | Sep 30, 24 |
| 3 | Vanguard Total Stock Mkt Idx Inv | 2.85M (3.71%) | 202.24K Increased by +7.10% | Oct 31, 24 |
| 4 | iShares Russell 2000 ETF | 2.33M (3.03%) | -4.87K Decreased by -0.21% | Nov 27, 24 |
| 5 | Janus Henderson Glb Life Scn I2 USD | 2.23M (2.90%) | 27.10K Increased by +1.22% | Oct 31, 24 |
| 6 | Janus Global Life Science AUSD | 2.20M (2.87%) | 11.58K Increased by +0.53% | Sep 30, 24 |
| 7 | Janus Selection Global Life Science AUSD | 2.19M (2.85%) | -95.51K Decreased by -4.36% | Jun 30, 24 |
| 8 | Pictet Biotech | 2.04M (2.65%) | 2.04M Increased by +100.00% | Mar 31, 24 |
| 9 | Pictet-Biotech P USD | 2.03M (2.65%) | 15.66K Increased by +0.77% | Aug 31, 24 |
| 10 | Harbor Small Cap Growth Instl | 1.45M (1.88%) | 341.00K Increased by +23.56% | Sep 30, 24 |
| 11 | SPDR® S&P Biotech ETF | 1.40M (1.82%) | -42.39K Decreased by -3.04% | Nov 27, 24 |
| 12 | Janus Henderson Triton D | 1.39M (1.80%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 13 | Janus Henderson US SMID Cap Growth | 1.39M (1.80%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 14 | Janus Henderson US SMID Cap Growth MA | 1.39M (1.80%) | 1.39M Increased by +100.00% | Sep 30, 24 |
| 15 | Vanguard Institutional Extnd Mkt Idx Tr | 1.29M (1.67%) | -4.91K Decreased by -0.38% | Oct 31, 24 |
| 16 | Pictet-Global Megatrend Sel I USD | 1.19M (1.55%) | -188.49K Decreased by -15.82% | Aug 31, 24 |
| 17 | Westfield Capital Mgt Co Sm-Cap Gr Eq | 1.11M (1.44%) | 105.17K Increased by +9.51% | Jun 30, 24 |
| 18 | Federated Hermes Kaufmann Growth | 1.09M (1.42%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 19 | Federated Hermes Kaufmann R | 1.09M (1.42%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 20 | Candriam Eqs L Biotech C USD Cap | 1.06M (1.37%) | 207.58K Increased by +19.66% | Oct 31, 24 |