| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | TANG CAPITAL MANAGEMENT LLC | 5.00M (9.19%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 2 | BlackRock Inc | 4.32M (7.95%) | -41.36K Decreased by -0.96% | Mar 31, 25 |
| 3 | Perceptive Advisors LLC | 4.13M (7.60%) | -1.02M Decreased by -24.62% | Mar 31, 25 |
| 4 | Nantahala Capital Management, LLC | 3.65M (6.72%) | 521.19K Increased by +14.27% | Mar 31, 25 |
| 5 | Vanguard Group Inc | 3.23M (5.95%) | 62.66K Increased by +1.94% | Mar 31, 25 |
| 6 | Caligan Partners LP | 2.73M (5.02%) | 38.77K Increased by +1.42% | Mar 31, 25 |
| 7 | First Manhattan Co. LLC | 2.29M (4.21%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 8 | Millennium Management LLC | 1.39M (2.56%) | 23.61K Increased by +1.70% | Mar 31, 25 |
| 9 | State Street Corp | 1.38M (2.54%) | -39.16K Decreased by -2.83% | Mar 31, 25 |
| 10 | Geode Capital Management, LLC | 1.26M (2.32%) | 47.45K Increased by +3.76% | Mar 31, 25 |
| 11 | Frontier Capital Management CO Inc | 1.21M (2.22%) | 967.48K Increased by +80.14% | Mar 31, 25 |
| 12 | BOOTHBAY FUND MANAGEMENT, LLC | 1.14M (2.10%) | -146.54K Decreased by -12.84% | Mar 31, 25 |
| 13 | Stonepine Capital Management Llc | 1.13M (2.09%) | -130.08K Decreased by -11.46% | Mar 31, 25 |
| 14 | Soleus Capital Management, L.P. | 1.08M (1.99%) | 382.00K Increased by +35.40% | Mar 31, 25 |
| 15 | Schroder Investment Management Group | 1.05M (1.93%) | 8.96K Increased by +0.85% | Mar 31, 25 |
| 16 | State Street Corporation | 1.03M (1.90%) | 6.19K Increased by +0.60% | Mar 31, 24 |
| 17 | Nuveen, LLC | 1.02M (1.89%) | 1.02M Increased by +100.00% | Mar 31, 25 |
| 18 | Soros Fund Management LLC | 995.49K (1.83%) | -104.52K Decreased by -10.50% | Mar 31, 25 |
| 19 | Lord, Abbett & Co LLC | 995.45K (1.83%) | -618.08K Decreased by -62.09% | Sep 30, 24 |
| 20 | Assenagon Asset Management SA | 955.55K (1.76%) | 8.45K Increased by +0.88% | Sep 30, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | BioPharma Credit Ord | 5.66M (10.41%) | -99.14K Decreased by -1.75% | Dec 31, 24 |
| 2 | Vanguard Total Stock Mkt Idx Inv | 1.73M (3.17%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 3 | Vanguard US Total Market Shares ETF | 1.68M (3.10%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 4 | iShares Russell 2000 ETF | 1.28M (2.36%) | -20.75K Decreased by -1.62% | Jul 30, 25 |
| 5 | Vanguard Institutional Extnd Mkt Idx Tr | 782.00K (1.44%) | 3.34K Increased by +0.43% | Jun 30, 25 |
| 6 | Schroder US Smaller Companies Acc | 764.91K (1.41%) | 4.05K Increased by +0.53% | Jun 30, 25 |
| 7 | Xtrackers S&P 500 Swap ETF 1C | 731.43K (1.35%) | 0.00 Increased by 0.00% | Jun 30, 24 |
| 8 | Oberweis Micro-Cap | 677.60K (1.25%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 9 | Oberweis Micro-Cap Growth | 677.60K (1.25%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 10 | CREF Stock R1 | 572.75K (1.05%) | 245.42K Increased by +42.85% | Feb 28, 25 |
| 11 | Fidelity Small Cap Index | 565.41K (1.04%) | -2.53K Decreased by -0.45% | May 31, 25 |
| 12 | Nuveen Quant Small Cap Equity R6 | 465.95K (0.86%) | 4.70K Increased by +1.01% | May 31, 25 |
| 13 | iShares Russell 2000 Growth ETF | 465.23K (0.86%) | -1.16K Decreased by -0.25% | Jul 30, 25 |
| 14 | Nuveen Quant Small Cap Equity Instl | 463.37K (0.85%) | 9.34K Increased by +2.02% | Feb 29, 24 |
| 15 | TIAA-CREF Quant Small-Cap Equity Instl | 454.03K (0.84%) | 0.00 Increased by 0.00% | Dec 31, 23 |
| 16 | Frontier Small Cap Growth | 429.44K (0.79%) | -30.89K Decreased by -7.19% | Jun 30, 25 |
| 17 | Fidelity® Small Cap Index | 401.19K (0.74%) | 11.60K Increased by +2.89% | Oct 31, 23 |
| 18 | Sun Life Schroder Global Mid Cap F | 346.01K (0.64%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 19 | CREF Stock R3 | 331.96K (0.61%) | -164.54K Decreased by -49.57% | May 31, 25 |
| 20 | State St Russell Sm/Mid Cp® Indx NL Cl C | 313.45K (0.58%) | 1.35K Increased by +0.43% | Apr 30, 25 |