| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Avidity Partners Management LP | 6.36M (7.58%) | 310.00K Increased by +4.87% | Dec 31, 23 |
| 2 | BlackRock Inc | 6.35M (7.56%) | -217.75K Decreased by -3.43% | Mar 31, 25 |
| 3 | State Street Corporation | 5.12M (6.10%) | -233.72K Decreased by -4.57% | Dec 31, 23 |
| 4 | Pfizer Inc | 4.69M (5.59%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 5 | Vanguard Group Inc | 4.52M (5.39%) | -43.41K Decreased by -0.96% | Mar 31, 25 |
| 6 | Deerfield Management Co | 3.50M (4.17%) | 3.50M Increased by +100.00% | Sep 30, 23 |
| 7 | Kynam Capital Management, LP | 3.27M (3.89%) | 863.00K Increased by +26.40% | Mar 31, 25 |
| 8 | Alkeon Capital Management, LLC | 3.11M (3.71%) | 1.47M Increased by +47.17% | Dec 31, 23 |
| 9 | Paradigm Biocapital Advisors LP | 2.92M (3.48%) | -20.66K Decreased by -0.71% | Dec 31, 23 |
| 10 | Morgan Stanley - Brokerage Accounts | 2.75M (3.28%) | 1.55M Increased by +56.42% | Dec 31, 24 |
| 11 | Rokos Capital Management LLP | 2.75M (3.27%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 12 | Assenagon Asset Management SA | 2.65M (3.16%) | 1.89M Increased by +71.23% | Sep 30, 23 |
| 13 | Partner Fund Management LP | 2.51M (2.99%) | -1.37M Decreased by -54.66% | Mar 31, 25 |
| 14 | Schonfeld Strategic Advisors LLC | 2.11M (2.52%) | 467.74K Increased by +22.13% | Dec 31, 24 |
| 15 | Geode Capital Management, LLC | 2.05M (2.45%) | 81.53K Increased by +3.97% | Mar 31, 25 |
| 16 | Elmwood Wealth Management, Inc. | 2.03M (2.41%) | -150.00K Decreased by -7.40% | Dec 31, 24 |
| 17 | State Street Corp | 1.64M (1.96%) | -16.38K Decreased by -1.00% | Mar 31, 25 |
| 18 | Two Sigma Advisers, LLC | 1.51M (1.80%) | 36.50K Increased by +2.42% | Mar 31, 25 |
| 19 | FMR Inc | 1.46M (1.74%) | -187.11K Decreased by -12.81% | Mar 31, 25 |
| 20 | Jacobs Levy Equity Management, Inc. | 1.44M (1.72%) | 234.05K Increased by +16.23% | Mar 31, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | SPDR® S&P Biotech ETF | 4.54M (5.40%) | 24.19K Increased by +0.53% | Mar 31, 24 |
| 2 | Vanguard Total Stock Mkt Idx Inv | 2.70M (3.22%) | 0.00 Increased by 0.00% | Apr 30, 25 |
| 3 | iShares Russell 2000 ETF | 2.07M (2.47%) | 350.00 Increased by +0.02% | Apr 30, 25 |
| 4 | ACATIS Datini Valueflex Fonds A | 2.00M (2.38%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 5 | Selectra J. Lamarck Biotech A | 1.50M (1.79%) | 0.00 Increased by 0.00% | Apr 30, 25 |
| 6 | Vanguard Institutional Extnd Mkt Idx Tr | 1.23M (1.47%) | 0.00 Increased by 0.00% | Apr 30, 25 |
| 7 | Belfius Equities Cure C Cap | 1.15M (1.36%) | 0.00 Increased by 0.00% | Mar 31, 24 |
| 8 | Pictet-Biotech P USD | 1.09M (1.30%) | -241.00K Decreased by -22.12% | Jun 30, 23 |
| 9 | abrdn Life Sciences Investors | 897.58K (1.07%) | 486.44K Increased by +54.19% | Apr 30, 25 |
| 10 | Candriam Global Equities Oncology | 860.00K (1.02%) | 360.00K Increased by +41.86% | Dec 31, 23 |
| 11 | Fidelity Small Cap Index | 809.35K (0.96%) | 56.16K Increased by +6.94% | Feb 28, 25 |
| 12 | iShares Russell 2000 Value ETF | 789.99K (0.94%) | -2.68K Decreased by -0.34% | Apr 30, 25 |
| 13 | Fidelity® Small Cap Index | 724.39K (0.86%) | 22.01K Increased by +3.04% | Oct 31, 23 |
| 14 | Pictet-Global Megatrend Sel I USD | 672.75K (0.80%) | 1.38K Increased by +0.20% | Dec 31, 23 |
| 15 | iShares Biotechnology ETF | 561.24K (0.67%) | 570.00 Increased by +0.10% | Nov 27, 24 |
| 16 | Direxion Daily S&P Biotech Bull 3X ETF | 541.45K (0.65%) | -3.80K Decreased by -0.70% | Mar 31, 24 |
| 17 | State St Russell Sm/Mid Cp® Indx NL Cl C | 478.79K (0.57%) | 0.00 Increased by 0.00% | Apr 30, 25 |
| 18 | State St Russell Sm/Mid Cp® Indx SL Cl I | 478.79K (0.57%) | 0.00 Increased by 0.00% | Apr 30, 25 |
| 19 | Fidelity Extended Market Index | 466.71K (0.56%) | 7.47K Increased by +1.60% | Mar 31, 25 |
| 20 | Multi-Manager Small Cap Eq Strat Inst | 408.06K (0.49%) | 0.00 Increased by 0.00% | Apr 30, 25 |