| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Cormorant Asset Management, LLC | 2.38M (20.03%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 2 | Orbimed Advisors, LLC | 1.17M (9.88%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 3 | Octagon Capital Advisors LP | 1.11M (9.40%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 4 | Vanguard Group Inc | 599.50K (5.05%) | -72.56K Decreased by -12.10% | Jun 30, 25 |
| 5 | Prosight Management, LP | 579.89K (4.89%) | 4.76K Increased by +0.82% | Jun 30, 25 |
| 6 | Adage Capital Partners Gp LLC | 528.94K (4.46%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 7 | Altium Capital Management, LP | 385.00K (3.25%) | 190.00K Increased by +49.35% | Dec 31, 24 |
| 8 | BlackRock Inc | 352.41K (2.97%) | -493.65K Decreased by -140.08% | Jun 30, 25 |
| 9 | Darwin Global Management, Ltd. | 325.14K (2.74%) | 325.14K Increased by +100.00% | Jun 30, 24 |
| 10 | Ikarian Capital, LLC | 284.71K (2.40%) | -24.82K Decreased by -8.72% | Sep 30, 24 |
| 11 | Exome Asset Management LLC | 277.32K (2.34%) | -12.37K Decreased by -4.46% | Jun 30, 25 |
| 12 | Woodline Partners LP | 249.26K (2.10%) | 208.28K Increased by +83.56% | Jun 30, 24 |
| 13 | Sio Capital Management, LLC | 225.16K (1.90%) | 225.16K Increased by +100.00% | Jun 30, 24 |
| 14 | State Street Corp | 223.47K (1.88%) | -5.13K Decreased by -2.30% | Mar 31, 25 |
| 15 | Assenagon Asset Management SA | 221.18K (1.87%) | -17.57K Decreased by -7.95% | Sep 30, 24 |
| 16 | Point72 Asset Management, L.P. | 216.51K (1.83%) | -485.08K Decreased by -224.04% | Jun 30, 24 |
| 17 | Avidity Partners Management LP | 215.60K (1.82%) | 215.60K Increased by +100.00% | Jun 30, 24 |
| 18 | HHG PLC | 203.27K (1.71%) | -135.80K Decreased by -66.81% | Jun 30, 24 |
| 19 | Comerica Bank | 200.00K (1.69%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 20 | Armistice Capital, LLC | 192.00K (1.62%) | -58.00K Decreased by -30.21% | Jun 30, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Biotech Growth Ord | 395.30K (3.33%) | 0.00 Increased by 0.00% | May 31, 25 |
| 2 | Vanguard Total Stock Mkt Idx Inv | 375.85K (3.17%) | -8.28K Decreased by -2.20% | Jul 31, 25 |
| 3 | SPDR® S&P Biotech ETF | 373.01K (3.15%) | -11.34K Decreased by -3.04% | Nov 27, 24 |
| 4 | Vanguard US Total Market Shares ETF | 329.22K (2.78%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 5 | abrdn Life Sciences Investors | 188.23K (1.59%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 6 | Vanguard Institutional Extnd Mkt Idx Tr | 126.07K (1.06%) | -48.36K Decreased by -38.36% | Jul 31, 25 |
| 7 | Fidelity Small Cap Index | 121.00K (1.02%) | -1.38K Decreased by -1.14% | May 31, 25 |
| 8 | Global X Marijuana Life Sciences ETF | 117.70K (0.99%) | -1.35K Decreased by -1.15% | Jul 31, 25 |
| 9 | HBM Healthcare Investments AG Ord | 117.50K (0.99%) | -202.50K Decreased by -172.35% | Jun 30, 25 |
| 10 | HealthInvest Sustainable Healthcare E | 113.08K (0.95%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 11 | Nuveen Quant Small Cap Equity R6 | 98.90K (0.83%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 12 | State St Russell Sm/Mid Cp® Indx NL Cl C | 66.91K (0.56%) | 0.00 Increased by 0.00% | Apr 30, 25 |
| 13 | State St Russell Sm/Mid Cp® Indx SL Cl I | 66.91K (0.56%) | 0.00 Increased by 0.00% | May 31, 25 |
| 14 | Victory Science & Technology | 65.88K (0.56%) | -156.00 Decreased by -0.24% | Dec 31, 24 |
| 15 | Fidelity Extended Market Index | 65.68K (0.55%) | -540.00 Decreased by -0.82% | Jul 31, 25 |
| 16 | HealthInvest Alpha Fund C | 62.51K (0.53%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 17 | Healthlnvest S&M Cap Healthcare C | 62.51K (0.53%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 18 | iShares Russell 2000 ETF | 62.36K (0.53%) | -8.34K Decreased by -13.38% | Jun 30, 25 |
| 19 | iShares Russell 2000 Growth ETF | 62.15K (0.52%) | 0.00 Increased by 0.00% | May 31, 25 |
| 20 | Vanguard Russell 2000 ETF | 57.94K (0.49%) | 530.00 Increased by +0.91% | May 31, 25 |