| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Cormorant Asset Management, LLC | 2.38M (31.56%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 2 | Orbimed Advisors, LLC | 1.17M (15.58%) | 259.74K Increased by +22.16% | Dec 31, 24 |
| 3 | Octagon Capital Advisors LP | 1.11M (14.81%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 4 | BlackRock Inc | 873.37K (11.60%) | 70.65K Increased by +8.09% | Dec 31, 24 |
| 5 | Vanguard Group Inc | 659.20K (8.76%) | 13.55K Increased by +2.06% | Dec 31, 24 |
| 6 | Adage Capital Partners Gp LLC | 528.94K (7.03%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 7 | Millennium Management LLC | 386.65K (5.14%) | 283.90K Increased by +73.43% | Dec 31, 24 |
| 8 | Altium Capital Management, LP | 385.00K (5.12%) | 190.00K Increased by +49.35% | Dec 31, 24 |
| 9 | Citadel Advisors Llc | 332.76K (4.42%) | 332.76K Increased by +100.00% | Jun 30, 24 |
| 10 | Darwin Global Management, Ltd. | 325.14K (4.32%) | 325.14K Increased by +100.00% | Jun 30, 24 |
| 11 | Ikarian Capital, LLC | 284.71K (3.78%) | -24.82K Decreased by -8.72% | Sep 30, 24 |
| 12 | Prosight Management, LP | 270.00K (3.59%) | 140.00K Increased by +51.85% | Dec 31, 24 |
| 13 | Geode Capital Management, LLC | 263.53K (3.50%) | 13.77K Increased by +5.23% | Dec 31, 24 |
| 14 | Woodline Partners LP | 249.26K (3.31%) | 208.28K Increased by +83.56% | Jun 30, 24 |
| 15 | TANG CAPITAL MANAGEMENT LLC | 242.65K (3.22%) | -357.35K Decreased by -147.27% | Dec 31, 24 |
| 16 | Armistice Capital, LLC | 236.00K (3.14%) | 236.00K Increased by +100.00% | Dec 31, 24 |
| 17 | State Street Corp | 228.60K (3.04%) | -366.98K Decreased by -160.53% | Dec 31, 24 |
| 18 | Sio Capital Management, LLC | 225.16K (2.99%) | 225.16K Increased by +100.00% | Jun 30, 24 |
| 19 | Assenagon Asset Management SA | 221.18K (2.94%) | -17.57K Decreased by -7.95% | Sep 30, 24 |
| 20 | Point72 Asset Management, L.P. | 216.51K (2.88%) | -485.08K Decreased by -224.04% | Jun 30, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Biotech Growth Ord | 395.30K (5.25%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 2 | Vanguard Total Stock Mkt Idx Inv | 384.13K (5.10%) | 21.91K Increased by +5.70% | Feb 28, 25 |
| 3 | SPDR® S&P Biotech ETF | 373.01K (4.96%) | -11.34K Decreased by -3.04% | Nov 27, 24 |
| 4 | HBM Healthcare Investments AG Ord | 320.00K (4.25%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 5 | iShares Russell 2000 ETF | 310.97K (4.13%) | -2.69K Decreased by -0.87% | Mar 31, 25 |
| 6 | Vanguard Institutional Extnd Mkt Idx Tr | 174.43K (2.32%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 7 | Global X Marijuana Life Sciences ETF | 151.01K (2.01%) | -2.17K Decreased by -1.44% | Feb 28, 25 |
| 8 | Fidelity Small Cap Index | 114.02K (1.51%) | -2.13K Decreased by -1.87% | Jan 31, 25 |
| 9 | Nuveen Quant Small Cap Equity R6 | 98.90K (1.31%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 10 | HealthInvest Sustainable Healthcare E | 70.64K (0.94%) | 0.00 Increased by 0.00% | Jan 31, 25 |
| 11 | State St Russell Sm/Mid Cp® Indx NL Cl C | 66.91K (0.89%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 12 | Fidelity Extended Market Index | 66.81K (0.89%) | 14.44K Increased by +21.62% | Feb 28, 25 |
| 13 | Victory Science & Technology | 65.88K (0.88%) | -156.00 Decreased by -0.24% | Dec 31, 24 |
| 14 | iShares Russell 2000 Growth ETF | 63.90K (0.85%) | -304.00 Decreased by -0.48% | Mar 31, 25 |
| 15 | Schwab US Small-Cap ETF™ | 55.60K (0.74%) | 200.00 Increased by +0.36% | Mar 29, 25 |
| 16 | Vanguard Russell 2000 ETF | 52.87K (0.70%) | 1.27K Increased by +2.40% | Feb 28, 25 |
| 17 | iShares Russell 2000 Value ETF | 45.67K (0.61%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 18 | State St Russell Sm Cap® Indx SL Cl I | 35.90K (0.48%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 19 | Vanguard US Momentum Factor ETF | 35.14K (0.47%) | 19.48K Increased by +55.43% | Sep 30, 24 |
| 20 | Bridge Builder Small/Mid Cap Growth | 31.30K (0.42%) | 4.01K Increased by +12.81% | Aug 31, 24 |