| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | MPM Oncology Impact Management LP | 14.71M (34.43%) | 0.00 Increased by 0.00% | Sep 30, 25 |
| 2 | Blue Owl Capital Holdings LP | 7.43M (17.40%) | 25.00K Increased by +0.34% | Dec 31, 25 |
| 3 | Deep Track Capital, LP | 7.42M (17.37%) | 0.00 Increased by 0.00% | Sep 30, 25 |
| 4 | Nextech Invest AG | 7.42M (17.37%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 5 | Nextech Invest, Ltd. | 7.42M (17.37%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 6 | Avidity Partners Management LP | 5.50M (12.89%) | -3.48M Decreased by -63.16% | Dec 31, 25 |
| 7 | Great Point Partners LLC | 4.68M (10.96%) | 0.00 Increased by 0.00% | Sep 30, 25 |
| 8 | Franklin Resources Inc | 4.00M (9.37%) | 0.00 Increased by 0.00% | Sep 30, 25 |
| 9 | Vanguard Group Inc | 3.79M (8.86%) | 290.88K Increased by +7.68% | Dec 31, 25 |
| 10 | Blackstone Inc | 2.44M (5.71%) | 0.00 Increased by 0.00% | Sep 30, 25 |
| 11 | Nantahala Capital Management, LLC | 1.94M (4.53%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 12 | Alyeska Investment Group, L.P. | 1.66M (3.89%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 13 | Sio Capital Management, LLC | 1.34M (3.14%) | 0.00 Increased by 0.00% | Sep 30, 25 |
| 14 | Velan Capital Investment Management LP | 1.29M (3.02%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 15 | Ally Bridge Group (NY) LLC | 1.16M (2.71%) | -419.31K Decreased by -36.23% | Mar 31, 25 |
| 16 | Opaleye Management Inc | 975.00K (2.28%) | 975.00K Increased by +100.00% | Dec 31, 23 |
| 17 | Allostery Investments LP | 950.17K (2.22%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 18 | BlackRock Inc | 848.97K (1.99%) | 0.00 Increased by 0.00% | Sep 30, 25 |
| 19 | UBS Group AG | 699.13K (1.64%) | 697.41K Increased by +99.75% | Dec 31, 24 |
| 20 | Woodline Partners LP | 680.19K (1.59%) | -681.00K Decreased by -100.12% | Jun 30, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard US Total Market Shares ETF | 3.12M (7.30%) | -6.75K Decreased by -0.22% | Sep 30, 24 |
| 2 | Vanguard Total Stock Mkt Idx Inv | 2.82M (6.59%) | 0.00 Increased by 0.00% | Jan 31, 26 |
| 3 | Franklin Biotechnology Discv A(acc)USD | 2.52M (5.91%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 4 | Franklin Biotechnology Discovery A | 1.48M (3.46%) | 0.00 Increased by 0.00% | Jan 31, 26 |
| 5 | Vanguard Institutional Extnd Mkt Idx Tr | 520.90K (1.22%) | 0.00 Increased by 0.00% | Jan 31, 26 |
| 6 | Calamos Market Neutral Income A | 277.81K (0.65%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 7 | Belfund SICAV Belinvest Equity A USD Acc | 260.00K (0.61%) | 0.00 Increased by 0.00% | Oct 31, 25 |
| 8 | Fidelity Extended Market Index | 247.33K (0.58%) | -1.03K Decreased by -0.42% | Jan 31, 26 |
| 9 | Blackrock Extended Mkt Fund CF | 120.30K (0.28%) | 120.30K Increased by +100.00% | Jan 31, 26 |
| 10 | Bridgeway Ultra-Small Company | 105.81K (0.25%) | 0.00 Increased by 0.00% | Dec 31, 23 |
| 11 | BlackRock Extended Equity Market K | 104.84K (0.25%) | -45.00 Decreased by -0.04% | Sep 30, 24 |
| 12 | Extended Equity Market Fund K | 103.18K (0.24%) | 67.00 Increased by +0.06% | Dec 31, 25 |
| 13 | Fidelity Total Market Index | 97.61K (0.23%) | 0.00 Increased by 0.00% | Jan 31, 26 |
| 14 | Spartan Extended Market Index Pool F | 87.43K (0.20%) | 1.03K Increased by +1.17% | Jan 31, 26 |
| 15 | Vanguard Instl Ttl Stck Mkt Idx Tr | 83.71K (0.20%) | 0.00 Increased by 0.00% | Jan 31, 26 |
| 16 | NT Ext Equity Mkt Idx Fd - L | 77.73K (0.18%) | 19.05K Increased by +24.50% | Dec 31, 25 |
| 17 | Fidelity® Extended Market Index | 76.47K (0.18%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 18 | Spartan Extended Market Index Pool E | 75.96K (0.18%) | 2.48K Increased by +3.27% | Mar 31, 25 |
| 19 | Fidelity Series Total Market Index | 70.42K (0.16%) | 0.00 Increased by 0.00% | Jan 31, 26 |
| 20 | Fidelity Nasdaq Composite Index | 63.70K (0.15%) | 0.00 Increased by 0.00% | Jan 31, 26 |