| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Kynam Capital Management, LP | 6.10M (10.85%) | -399.27K Decreased by -6.54% | Jun 30, 25 |
| 2 | BlackRock Inc | 5.55M (9.87%) | 25.88K Increased by +0.47% | Jun 30, 25 |
| 3 | FMR Inc | 5.44M (9.67%) | 59.03K Increased by +1.09% | Jun 30, 25 |
| 4 | Wellington Management Company LLP | 5.23M (9.30%) | -3.12M Decreased by -59.66% | Jun 30, 25 |
| 5 | Vanguard Group Inc | 3.96M (7.04%) | 58.69K Increased by +1.48% | Jun 30, 25 |
| 6 | T. Rowe Price Associates, Inc. | 3.82M (6.79%) | 407.32K Increased by +10.67% | Jun 30, 25 |
| 7 | RTW INVESTMENTS, LLC | 3.46M (6.16%) | 0.00 Increased by 0.00% | Dec 31, 23 |
| 8 | COMMODORE CAPITAL LP | 3.45M (6.13%) | 250.00K Increased by +7.25% | Jun 30, 25 |
| 9 | Bellevue Group AG | 3.31M (5.88%) | 235.95K Increased by +7.13% | Jun 30, 25 |
| 10 | State Street Corporation | 2.98M (5.30%) | 602.42K Increased by +20.22% | Mar 31, 24 |
| 11 | Point72 Asset Management, L.P. | 2.80M (4.98%) | 180.55K Increased by +6.44% | Jun 30, 25 |
| 12 | State Street Corp | 2.41M (4.28%) | -400.86K Decreased by -16.66% | Jun 30, 25 |
| 13 | Jefferies Financial Group Inc | 2.39M (4.25%) | 2.37M Increased by +99.12% | Dec 31, 24 |
| 14 | Deep Track Capital, LP | 2.00M (3.56%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 15 | Vestal Point Capital LP | 1.75M (3.11%) | 1.55M Increased by +88.65% | Jun 30, 25 |
| 16 | T. Rowe Price Investment Management,Inc. | 1.70M (3.02%) | -37.02K Decreased by -2.18% | Dec 31, 24 |
| 17 | Geode Capital Management, LLC | 1.67M (2.97%) | 83.17K Increased by +4.97% | Jun 30, 25 |
| 18 | Woodline Partners LP | 1.50M (2.67%) | 312.03K Increased by +20.80% | Jun 30, 25 |
| 19 | Marshall Wace Asset Management Ltd | 1.38M (2.45%) | 479.07K Increased by +34.77% | Jun 30, 24 |
| 20 | Eventide Asset Management, LLC | 1.36M (2.41%) | -2.40M Decreased by -176.86% | Jun 30, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | BB Biotech AG Ord | 3.07M (5.46%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 2 | Eventide Gilead N | 2.38M (4.23%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 3 | Vanguard Total Stock Mkt Idx Inv | 2.14M (3.80%) | -44.27K Decreased by -2.07% | Jul 31, 25 |
| 4 | Vanguard Health Care Inv | 2.12M (3.77%) | -2.43M Decreased by -114.49% | Jun 30, 25 |
| 5 | Vanguard US Total Market Shares ETF | 2.07M (3.68%) | 2.12K Increased by +0.10% | Sep 30, 24 |
| 6 | iShares Russell 2000 ETF | 1.57M (2.79%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 7 | US Small-Cap Growth II Equity Comp | 1.39M (2.47%) | -121.70K Decreased by -8.75% | Jun 30, 25 |
| 8 | Eventide Healthcare & Life Sciences I | 1.36M (2.41%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 9 | Polar Capital Biotech S Inc | 1.23M (2.18%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 10 | Polar Capital Healthcare Opports Inc | 1.15M (2.04%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 11 | Fidelity Advisor® Biotechnology I | 1.07M (1.91%) | -257.15K Decreased by -23.94% | Nov 30, 23 |
| 12 | T. Rowe Price New Horizons | 989.25K (1.76%) | -401.26K Decreased by -40.56% | Jul 31, 25 |
| 13 | Fidelity Advisor Growth Opps M | 936.70K (1.67%) | 20.80K Increased by +2.22% | Mar 31, 24 |
| 14 | Fidelity Advisor® Growth Opps M | 915.90K (1.63%) | 111.90K Increased by +12.22% | Nov 30, 23 |
| 15 | Fidelity® Select Biotechnology | 907.20K (1.61%) | 184.00K Increased by +20.28% | Nov 30, 23 |
| 16 | SPDR® S&P Biotech ETF | 871.82K (1.55%) | 1.95K Increased by +0.22% | Aug 31, 25 |
| 17 | T. Rowe Price Integrated US SmCapGrEq | 851.45K (1.51%) | 567.31K Increased by +66.63% | Dec 31, 24 |
| 18 | Fidelity Contrafund | 767.20K (1.36%) | 0.00 Increased by 0.00% | Jun 30, 24 |
| 19 | Vanguard Explorer Inv | 744.95K (1.32%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 20 | Pictet Biotech | 722.82K (1.29%) | 722.82K Increased by +100.00% | Mar 31, 24 |