| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Wellington Management Company LLP | 8.98M (15.53%) | -267.77K Decreased by -2.98% | Dec 31, 24 |
| 2 | BlackRock Inc | 5.48M (9.48%) | 600.65K Increased by +10.96% | Dec 31, 24 |
| 3 | Kynam Capital Management, LP | 5.06M (8.76%) | 1.61M Increased by +31.70% | Dec 31, 24 |
| 4 | FMR Inc | 4.86M (8.41%) | -1.17M Decreased by -24.02% | Dec 31, 24 |
| 5 | Vanguard Group Inc | 3.88M (6.72%) | 12.21K Increased by +0.31% | Dec 31, 24 |
| 6 | Eventide Asset Management, LLC | 3.75M (6.50%) | 421.25K Increased by +11.22% | Dec 31, 24 |
| 7 | T. Rowe Price Associates, Inc. | 3.56M (6.16%) | 676.77K Increased by +19.03% | Dec 31, 24 |
| 8 | RTW INVESTMENTS, LLC | 3.46M (5.99%) | 0.00 Increased by 0.00% | Dec 31, 23 |
| 9 | State Street Corp | 3.23M (5.60%) | 749.80K Increased by +23.18% | Dec 31, 24 |
| 10 | Bellevue Group AG | 3.07M (5.32%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 11 | State Street Corporation | 2.98M (5.16%) | 602.42K Increased by +20.22% | Mar 31, 24 |
| 12 | Point72 Asset Management, L.P. | 2.52M (4.35%) | 947.26K Increased by +37.65% | Dec 31, 24 |
| 13 | Jefferies Financial Group Inc | 2.39M (4.14%) | 2.37M Increased by +99.12% | Dec 31, 24 |
| 14 | Woodline Partners LP | 2.01M (3.49%) | -327.11K Decreased by -16.24% | Dec 31, 24 |
| 15 | T. Rowe Price Investment Management,Inc. | 1.70M (2.94%) | -37.02K Decreased by -2.18% | Dec 31, 24 |
| 16 | COMMODORE CAPITAL LP | 1.62M (2.80%) | 193.94K Increased by +11.98% | Sep 30, 24 |
| 17 | Polar Capital Holdings PLC | 1.57M (2.71%) | -1.16M Decreased by -73.77% | Dec 31, 24 |
| 18 | Deep Track Capital, LP | 1.54M (2.67%) | 1.54M Increased by +100.00% | Dec 31, 24 |
| 19 | Geode Capital Management, LLC | 1.53M (2.66%) | -5.60K Decreased by -0.36% | Dec 31, 24 |
| 20 | Marshall Wace Asset Management Ltd | 1.38M (2.38%) | 479.07K Increased by +34.77% | Jun 30, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Health Care Inv | 4.55M (7.87%) | 7.20K Increased by +0.16% | Dec 31, 24 |
| 2 | BB Biotech AG Ord | 3.07M (5.32%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 3 | Eventide Gilead N | 2.38M (4.12%) | 413.90K Increased by +17.39% | Dec 31, 24 |
| 4 | Vanguard Total Stock Mkt Idx Inv | 2.09M (3.62%) | 2.31K Increased by +0.11% | Feb 28, 25 |
| 5 | iShares Russell 2000 ETF | 1.70M (2.94%) | -14.74K Decreased by -0.87% | Mar 31, 25 |
| 6 | T. Rowe Price New Horizons | 1.53M (2.65%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 7 | US Small-Cap Growth II Equity Comp | 1.45M (2.50%) | 395.64K Increased by +27.35% | Dec 31, 24 |
| 8 | Eventide Healthcare & Life Sciences I | 1.36M (2.35%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 9 | SPDR® S&P Biotech ETF | 1.33M (2.30%) | -14.23K Decreased by -1.07% | Mar 31, 25 |
| 10 | Polar Capital Biotech S Inc | 1.25M (2.16%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 11 | Polar Capital Healthcare Opports Inc | 1.15M (1.98%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 12 | Vanguard Explorer Inv | 1.13M (1.96%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 13 | Fidelity Advisor® Biotechnology I | 1.07M (1.86%) | -257.15K Decreased by -23.94% | Nov 30, 23 |
| 14 | Vanguard Institutional Extnd Mkt Idx Tr | 1.00M (1.74%) | 5.92K Increased by +0.59% | Feb 28, 25 |
| 15 | Fidelity Advisor Growth Opps M | 936.70K (1.62%) | 20.80K Increased by +2.22% | Mar 31, 24 |
| 16 | Fidelity Advisor® Growth Opps M | 915.90K (1.59%) | 111.90K Increased by +12.22% | Nov 30, 23 |
| 17 | Fidelity® Select Biotechnology | 907.20K (1.57%) | 184.00K Increased by +20.28% | Nov 30, 23 |
| 18 | T. Rowe Price Integrated US SmCapGrEq | 851.45K (1.47%) | 567.31K Increased by +66.63% | Dec 31, 24 |
| 19 | Fidelity Contrafund | 767.20K (1.33%) | 0.00 Increased by 0.00% | Jun 30, 24 |
| 20 | Pictet Biotech | 722.82K (1.25%) | 722.82K Increased by +100.00% | Mar 31, 24 |