| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Kynam Capital Management, LP | 6.10M (11.47%) | -399.27K Decreased by -6.54% | Jun 30, 25 |
| 2 | BlackRock Inc | 5.52M (10.38%) | 43.46K Increased by +0.79% | Mar 31, 25 |
| 3 | FMR Inc | 5.38M (10.11%) | 522.42K Increased by +9.71% | Mar 31, 25 |
| 4 | Wellington Management Company LLP | 5.23M (9.83%) | -3.12M Decreased by -59.66% | Jun 30, 25 |
| 5 | Vanguard Group Inc | 3.96M (7.44%) | 58.69K Increased by +1.48% | Jun 30, 25 |
| 6 | T. Rowe Price Associates, Inc. | 3.82M (7.18%) | 407.32K Increased by +10.67% | Jun 30, 25 |
| 7 | Eventide Asset Management, LLC | 3.75M (7.06%) | 1.53K Increased by +0.04% | Mar 31, 25 |
| 8 | RTW INVESTMENTS, LLC | 3.46M (6.51%) | 0.00 Increased by 0.00% | Dec 31, 23 |
| 9 | Bellevue Group AG | 3.31M (6.22%) | 235.95K Increased by +7.13% | Jun 30, 25 |
| 10 | COMMODORE CAPITAL LP | 3.20M (6.01%) | 3.20M Increased by +100.00% | Mar 31, 25 |
| 11 | State Street Corporation | 2.98M (5.60%) | 602.42K Increased by +20.22% | Mar 31, 24 |
| 12 | State Street Corp | 2.81M (5.27%) | -428.60K Decreased by -15.27% | Mar 31, 25 |
| 13 | Point72 Asset Management, L.P. | 2.62M (4.93%) | 105.20K Increased by +4.01% | Mar 31, 25 |
| 14 | Jefferies Financial Group Inc | 2.39M (4.49%) | 2.37M Increased by +99.12% | Dec 31, 24 |
| 15 | Deep Track Capital, LP | 2.00M (3.76%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 16 | T. Rowe Price Investment Management,Inc. | 1.70M (3.19%) | -37.02K Decreased by -2.18% | Dec 31, 24 |
| 17 | Geode Capital Management, LLC | 1.59M (2.99%) | 54.89K Increased by +3.45% | Mar 31, 25 |
| 18 | UBS Group AG | 1.47M (2.76%) | 1.08M Increased by +73.45% | Mar 31, 25 |
| 19 | Polar Capital Holdings PLC | 1.40M (2.64%) | -162.40K Decreased by -11.57% | Mar 31, 25 |
| 20 | Marshall Wace Asset Management Ltd | 1.38M (2.59%) | 479.07K Increased by +34.77% | Jun 30, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | BB Biotech AG Ord | 3.07M (5.77%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 2 | Eventide Gilead N | 2.38M (4.47%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 3 | Vanguard Total Stock Mkt Idx Inv | 2.18M (4.10%) | 15.94K Increased by +0.73% | Jun 30, 25 |
| 4 | Vanguard Health Care Inv | 2.12M (3.99%) | -2.43M Decreased by -114.49% | Jun 30, 25 |
| 5 | Vanguard US Total Market Shares ETF | 2.07M (3.89%) | 2.12K Increased by +0.10% | Sep 30, 24 |
| 6 | iShares Russell 2000 ETF | 1.54M (2.89%) | -29.19K Decreased by -1.90% | Jul 31, 25 |
| 7 | T. Rowe Price New Horizons | 1.39M (2.61%) | -157.87K Decreased by -11.35% | Jun 30, 25 |
| 8 | US Small-Cap Growth II Equity Comp | 1.39M (2.61%) | -121.70K Decreased by -8.75% | Jun 30, 25 |
| 9 | Eventide Healthcare & Life Sciences I | 1.36M (2.55%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 10 | Polar Capital Biotech S Inc | 1.23M (2.30%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 11 | Polar Capital Healthcare Opports Inc | 1.15M (2.15%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 12 | Fidelity Advisor® Biotechnology I | 1.07M (2.02%) | -257.15K Decreased by -23.94% | Nov 30, 23 |
| 13 | Vanguard Institutional Extnd Mkt Idx Tr | 1.03M (1.93%) | -19.46K Decreased by -1.89% | Jun 30, 25 |
| 14 | Fidelity Advisor Growth Opps M | 936.70K (1.76%) | 20.80K Increased by +2.22% | Mar 31, 24 |
| 15 | Fidelity Advisor® Growth Opps M | 915.90K (1.72%) | 111.90K Increased by +12.22% | Nov 30, 23 |
| 16 | Fidelity® Select Biotechnology | 907.20K (1.71%) | 184.00K Increased by +20.28% | Nov 30, 23 |
| 17 | SPDR® S&P Biotech ETF | 871.82K (1.64%) | 26.06K Increased by +2.99% | Jul 31, 25 |
| 18 | T. Rowe Price Integrated US SmCapGrEq | 851.45K (1.60%) | 567.31K Increased by +66.63% | Dec 31, 24 |
| 19 | Fidelity Contrafund | 767.20K (1.44%) | 0.00 Increased by 0.00% | Jun 30, 24 |
| 20 | T. Rowe Price Health Sciences | 750.77K (1.41%) | 79.33K Increased by +10.57% | Jun 30, 25 |