| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | RTW INVESTMENTS, LLC | 6.98M (10.61%) | 4.97M Increased by +71.19% | Mar 31, 26 |
| 2 | T. Rowe Price Investment Management,Inc. | 6.72M (10.21%) | 6.26M Increased by +93.09% | Mar 31, 26 |
| 3 | Vanguard Group Inc | 6.54M (9.93%) | -37.80K Decreased by -0.58% | Dec 31, 25 |
| 4 | Decheng Capital LLC | 6.37M (9.68%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 5 | Wellington Management Company LLP | 5.37M (8.16%) | -628.56K Decreased by -11.70% | Mar 31, 26 |
| 6 | BlackRock Inc | 5.06M (7.69%) | 220.94K Increased by +4.36% | Mar 31, 26 |
| 7 | FMR Inc | 3.76M (5.72%) | -533.33K Decreased by -14.17% | Mar 31, 26 |
| 8 | TCG Crossover Management, LLC | 3.67M (5.58%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 9 | T. Rowe Price Associates, Inc. | 3.65M (5.55%) | 209.84K Increased by +5.74% | Mar 31, 26 |
| 10 | Vanguard Portfolio Management, LLC | 3.10M (4.70%) | 3.10M Increased by +100.00% | Mar 31, 26 |
| 11 | Vanguard Capital Management, LLC | 3.03M (4.61%) | 3.03M Increased by +100.00% | Mar 31, 26 |
| 12 | State Street Corp | 2.65M (4.02%) | -349.64K Decreased by -13.21% | Mar 31, 26 |
| 13 | Foresite Capital Management VI LLC | 2.22M (3.37%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 14 | Geode Capital Management, LLC | 1.60M (2.43%) | 85.33K Increased by +5.34% | Mar 31, 26 |
| 15 | Orbimed Advisors, LLC | 1.52M (2.30%) | -210.30K Decreased by -13.87% | Dec 31, 25 |
| 16 | Seven Fleet Capital Management LP | 1.52M (2.30%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 17 | Franklin Resources Inc | 1.51M (2.29%) | -54.57K Decreased by -3.62% | Mar 31, 26 |
| 18 | Bank of America Corp | 1.45M (2.20%) | 259.31K Increased by +17.89% | Mar 31, 26 |
| 19 | DV Trading LLC | 1.44M (2.19%) | 1.44M Increased by +100.00% | Dec 31, 25 |
| 20 | UBS Group AG | 1.31M (1.99%) | -611.77K Decreased by -46.63% | Mar 31, 26 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Health Care Inv | 2.93M (4.46%) | -295.38K Decreased by -10.07% | Mar 31, 26 |
| 2 | Vanguard Total Stock Mkt Idx Inv | 2.20M (3.34%) | 6.26K Increased by +0.28% | Apr 30, 26 |
| 3 | Vanguard Small Cap Index | 1.58M (2.40%) | -3.60K Decreased by -0.23% | Apr 30, 26 |
| 4 | State Street® SPDR® S&P® Biotech ETF | 1.41M (2.15%) | -8.70K Decreased by -0.62% | May 31, 26 |
| 5 | iShares Russell 2000 ETF | 1.41M (2.14%) | 13.05K Increased by +0.92% | May 29, 26 |
| 6 | Vanguard Small Cap Value Index Inv | 1.01M (1.54%) | 6.98K Increased by +0.69% | Apr 30, 26 |
| 7 | Fidelity Small Cap Growth | 909.86K (1.38%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 8 | Vanguard Institutional Extnd Mkt Idx Tr | 773.16K (1.17%) | 6.39K Increased by +0.83% | Apr 30, 26 |
| 9 | T. Rowe Price Health Sciences | 758.47K (1.15%) | -428.20K Decreased by -56.46% | Apr 30, 26 |
| 10 | T. Rowe Price US Mid-Cap Growth Equity | 745.29K (1.13%) | 745.29K Increased by +100.00% | Mar 31, 26 |
| 11 | T. Rowe Price Mid-Cap Growth | 744.97K (1.13%) | -323.00 Decreased by -0.04% | Apr 30, 26 |
| 12 | US Small-Cap Growth II Equity Comp | 742.33K (1.13%) | 18.83K Increased by +2.54% | Mar 31, 26 |
| 13 | T. Rowe Price New Horizons | 742.00K (1.13%) | -333.00 Decreased by -0.04% | Apr 30, 26 |
| 14 | T. Rowe Price Integrated US Sm Gr Eq | 631.78K (0.96%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 15 | T. Rowe Price Integrated US SmCapGrEq | 631.78K (0.96%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 16 | Polar Capital Healthcare Opports Inc | 627.45K (0.95%) | 0.00 Increased by 0.00% | Apr 30, 26 |
| 17 | Worldwide Healthcare Ord | 582.47K (0.88%) | 0.00 Increased by 0.00% | Feb 28, 26 |
| 18 | Fidelity Small Cap Index | 579.80K (0.88%) | 32.88K Increased by +5.67% | Mar 31, 26 |
| 19 | JNL/T. Rowe Price Capital Appreciation A | 569.85K (0.87%) | 569.85K Increased by +100.00% | Mar 31, 26 |
| 20 | Fidelity Select Health Care | 560.00K (0.85%) | -40.00K Decreased by -7.14% | Apr 30, 26 |