| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Baker Bros Advisors LP | 7.92M (26.61%) | 0.00 Increased by 0.00% | Mar 30, 26 |
| 2 | Bvf Inc | 3.47M (11.65%) | 0.00 Increased by 0.00% | Jun 29, 25 |
| 3 | venBio Select Advisor LLC | 3.38M (11.35%) | 263.89K Increased by +7.82% | Mar 30, 26 |
| 4 | Perceptive Advisors LLC | 3.13M (10.51%) | -33.00K Decreased by -1.06% | Mar 30, 26 |
| 5 | RTW INVESTMENTS, LLC | 3.04M (10.22%) | 2.49M Increased by +81.90% | Mar 30, 26 |
| 6 | BlackRock Inc | 2.71M (9.12%) | 171.16K Increased by +6.31% | Mar 30, 26 |
| 7 | NEA Management Company, LLC | 2.29M (7.68%) | -1.25M Decreased by -54.69% | Mar 30, 26 |
| 8 | Vanguard Group Inc | 2.28M (7.66%) | 220.39K Increased by +9.67% | Dec 30, 25 |
| 9 | Vanguard Capital Management, LLC | 1.78M (5.99%) | 1.78M Increased by +100.00% | Mar 30, 26 |
| 10 | Deerfield Management Co | 1.71M (5.76%) | 0.00 Increased by 0.00% | Mar 30, 26 |
| 11 | State Street Corp | 1.52M (5.11%) | -118.98K Decreased by -7.83% | Mar 30, 26 |
| 12 | RA Capital Management, LLC | 1.40M (4.71%) | 0.00 Increased by 0.00% | Sep 29, 23 |
| 13 | Eventide Asset Management, LLC | 1.39M (4.67%) | 123.77K Increased by +8.91% | Jun 29, 25 |
| 14 | Morgan Stanley - Brokerage Accounts | 1.35M (4.52%) | -53.26K Decreased by -3.96% | Mar 30, 26 |
| 15 | Soleus Capital Management, L.P. | 1.28M (4.32%) | -523.88K Decreased by -40.79% | Mar 30, 26 |
| 16 | T. Rowe Price Associates, Inc. | 1.28M (4.30%) | 39.53K Increased by +3.09% | Mar 30, 26 |
| 17 | Samlyn Capital, LLC | 1.25M (4.21%) | -39.34K Decreased by -3.14% | Dec 30, 24 |
| 18 | Saturn V Capital Management LLC | 1.19M (3.99%) | 91.84K Increased by +7.75% | Jun 29, 25 |
| 19 | TANG CAPITAL MANAGEMENT LLC | 1.05M (3.53%) | 0.00 Increased by 0.00% | Mar 30, 26 |
| 20 | VR Adviser, LLC | 970.00K (3.26%) | -1.14M Decreased by -117.05% | Mar 30, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Morn Total Stk Mkt Idx Investor | 1.39M (4.69%) | 64.40K Increased by +4.62% | Jun 29, 26 |
| 2 | Vanguard Total Stock Mkt Idx Inv | 1.39M (4.69%) | 64.40K Increased by +4.62% | Jun 29, 26 |
| 3 | State Street® SPDR® S&P® Biotech ETF | 1.11M (3.72%) | -11.02K Decreased by -1.00% | Jul 29, 26 |
| 4 | Vanguard US Total Market Shares ETF | 1.00M (3.38%) | 0.00 Increased by 0.00% | Sep 29, 24 |
| 5 | iShares Russell 2000 ETF | 990.32K (3.33%) | -720.00 Decreased by -0.07% | Jul 29, 26 |
| 6 | Columbia Small Cap Value Discovery Fund | 523.74K (1.76%) | 208.46K Increased by +39.80% | Jun 29, 25 |
| 7 | Columbia Small Cap Value I | 523.74K (1.76%) | 208.46K Increased by +39.80% | Jun 29, 25 |
| 8 | Fidelity Select Biotechnology | 479.20K (1.61%) | 103.60K Increased by +21.62% | Jun 29, 26 |
| 9 | Vanguard Institutional Extnd Mkt Idx Tr | 436.10K (1.47%) | 27.95K Increased by +6.41% | Jun 29, 26 |
| 10 | T. Rowe Price Health Sciences | 376.20K (1.26%) | -164.10K Decreased by -43.62% | Apr 29, 26 |
| 11 | iShares Russell 2000 Growth ETF | 351.70K (1.18%) | -456.00 Decreased by -0.13% | Jul 29, 26 |
| 12 | Fidelity Small Cap Index | 348.75K (1.17%) | 1.87K Increased by +0.54% | May 30, 26 |
| 13 | American Century Small Cap Growth Inv | 339.39K (1.14%) | 339.39K Increased by +100.00% | Jun 29, 26 |
| 14 | American Century U.S. Small Cap Growth | 339.39K (1.14%) | 339.39K Increased by +100.00% | Jun 29, 26 |
| 15 | SPDR® S&P Biotech ETF | 327.79K (1.10%) | -2.00K Decreased by -0.61% | Feb 27, 25 |
| 16 | Belfius Equities Cure C Cap | 302.31K (1.02%) | 0.00 Increased by 0.00% | Jan 30, 26 |
| 17 | T. Rowe Price Integrated US Sm Gr Eq | 289.54K (0.97%) | 106.20K Increased by +36.68% | Jun 29, 26 |
| 18 | T. Rowe Price Integrated US SmCapGrEq | 289.54K (0.97%) | 163.70K Increased by +56.54% | Jun 29, 26 |
| 19 | Artisan International Small-Mid Investor | 286.17K (0.96%) | 2.92K Increased by +1.02% | Jun 29, 26 |
| 20 | Artisan Non-U.S. Small-Mid Growth Comp | 286.17K (0.96%) | 2.92K Increased by +1.02% | Jun 29, 26 |