| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Baker Bros Advisors LP | 7.92M (29.52%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 2 | Bvf Inc | 3.47M (12.93%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 3 | venBio Select Advisor LLC | 3.38M (12.59%) | 263.89K Increased by +7.82% | Mar 31, 26 |
| 4 | Perceptive Advisors LLC | 3.13M (11.66%) | -33.00K Decreased by -1.06% | Mar 31, 26 |
| 5 | RTW INVESTMENTS, LLC | 3.04M (11.34%) | 2.49M Increased by +81.90% | Mar 31, 26 |
| 6 | BlackRock Inc | 2.71M (10.11%) | 171.16K Increased by +6.31% | Mar 31, 26 |
| 7 | NEA Management Company, LLC | 2.29M (8.52%) | -1.25M Decreased by -54.69% | Mar 31, 26 |
| 8 | Vanguard Group Inc | 2.28M (8.50%) | 220.39K Increased by +9.67% | Dec 31, 25 |
| 9 | Vanguard Capital Management, LLC | 1.78M (6.65%) | 1.78M Increased by +100.00% | Mar 31, 26 |
| 10 | Deerfield Management Co | 1.71M (6.39%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 11 | State Street Corp | 1.52M (5.66%) | -118.98K Decreased by -7.83% | Mar 31, 26 |
| 12 | RA Capital Management, LLC | 1.40M (5.22%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 13 | Eventide Asset Management, LLC | 1.39M (5.18%) | 123.77K Increased by +8.91% | Jun 30, 25 |
| 14 | Morgan Stanley - Brokerage Accounts | 1.35M (5.02%) | -53.26K Decreased by -3.96% | Mar 31, 26 |
| 15 | Soleus Capital Management, L.P. | 1.28M (4.79%) | -523.88K Decreased by -40.79% | Mar 31, 26 |
| 16 | T. Rowe Price Associates, Inc. | 1.28M (4.77%) | 39.53K Increased by +3.09% | Mar 31, 26 |
| 17 | Samlyn Capital, LLC | 1.25M (4.67%) | -39.34K Decreased by -3.14% | Dec 31, 24 |
| 18 | Saturn V Capital Management LLC | 1.19M (4.42%) | 91.84K Increased by +7.75% | Jun 30, 25 |
| 19 | TANG CAPITAL MANAGEMENT LLC | 1.05M (3.92%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 20 | VR Adviser, LLC | 970.00K (3.62%) | -1.14M Decreased by -117.05% | Mar 31, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 1.34M (5.00%) | 3.62K Increased by +0.27% | Apr 30, 26 |
| 2 | Vanguard US Total Market Shares ETF | 1.00M (3.75%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 3 | iShares Russell 2000 ETF | 839.28K (3.13%) | 7.75K Increased by +0.92% | May 29, 26 |
| 4 | State Street® SPDR® S&P® Biotech ETF | 810.09K (3.02%) | -4.98K Decreased by -0.61% | May 31, 26 |
| 5 | Columbia Small Cap Value Discovery Fund | 523.74K (1.95%) | 208.46K Increased by +39.80% | Jun 30, 25 |
| 6 | Columbia Small Cap Value I | 523.74K (1.95%) | 208.46K Increased by +39.80% | Jun 30, 25 |
| 7 | Vanguard Institutional Extnd Mkt Idx Tr | 407.72K (1.52%) | 4.17K Increased by +1.02% | Apr 30, 26 |
| 8 | T. Rowe Price Health Sciences | 376.20K (1.40%) | -164.10K Decreased by -43.62% | Apr 30, 26 |
| 9 | Fidelity Small Cap Index | 343.96K (1.28%) | 29.09K Increased by +8.46% | Mar 31, 26 |
| 10 | SPDR® S&P Biotech ETF | 327.79K (1.22%) | -2.00K Decreased by -0.61% | Feb 28, 25 |
| 11 | T. Rowe Price New Horizons | 308.74K (1.15%) | 62.67K Increased by +20.30% | Apr 30, 26 |
| 12 | Belfius Equities Cure C Cap | 302.31K (1.13%) | -61.87K Decreased by -20.47% | Nov 30, 25 |
| 13 | Artisan International Small-Mid Investor | 283.25K (1.06%) | -48.35K Decreased by -17.07% | Mar 31, 26 |
| 14 | Artisan Non-U.S. Small-Mid Growth Comp | 283.25K (1.06%) | -48.35K Decreased by -17.07% | Mar 31, 26 |
| 15 | iShares Russell 2000 Growth ETF | 270.91K (1.01%) | -1.76K Decreased by -0.65% | May 29, 26 |
| 16 | US Small-Cap Growth II Equity Comp | 246.07K (0.92%) | 48.27K Increased by +19.62% | Mar 31, 26 |
| 17 | Eventide Healthcare & Life Sciences I | 242.87K (0.91%) | -69.71K Decreased by -28.70% | Mar 31, 26 |
| 18 | State St Russell Sm/Mid Cp® Indx SL Cl I | 208.87K (0.78%) | 0.00 Increased by 0.00% | May 31, 26 |
| 19 | Russell 2000 Equity Index Fund B | 199.28K (0.74%) | 8.70K Increased by +4.37% | Dec 31, 25 |
| 20 | Candriam Eqs L Biotech C USD Cap | 195.99K (0.73%) | 6.12K Increased by +3.12% | Oct 31, 25 |