| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Baker Bros Advisors LP | 7.92M (26.69%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 2 | NEA Management Company, LLC | 3.54M (11.92%) | 1.39M Increased by +39.35% | Dec 31, 25 |
| 3 | Bvf Inc | 3.47M (11.69%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 4 | venBio Select Advisor LLC | 3.11M (10.49%) | 3.11M Increased by +100.00% | Dec 31, 25 |
| 5 | Perceptive Advisors LLC | 2.96M (9.97%) | 1.32M Increased by +44.76% | Sep 30, 25 |
| 6 | BlackRock Inc | 2.54M (8.57%) | 293.93K Increased by +11.57% | Dec 31, 25 |
| 7 | Vanguard Group Inc | 2.28M (7.69%) | 220.39K Increased by +9.67% | Dec 31, 25 |
| 8 | Soleus Capital Management, L.P. | 1.81M (6.10%) | 629.40K Increased by +34.81% | Dec 31, 25 |
| 9 | Deerfield Management Co | 1.71M (5.78%) | 980.47K Increased by +57.20% | Dec 31, 25 |
| 10 | State Street Corp | 1.64M (5.52%) | 914.89K Increased by +55.86% | Dec 31, 25 |
| 11 | RA Capital Management, LLC | 1.40M (4.72%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 12 | Morgan Stanley - Brokerage Accounts | 1.40M (4.72%) | -113.88K Decreased by -8.14% | Dec 31, 25 |
| 13 | Eventide Asset Management, LLC | 1.39M (4.69%) | 123.77K Increased by +8.91% | Jun 30, 25 |
| 14 | Samlyn Capital, LLC | 1.25M (4.22%) | -39.34K Decreased by -3.14% | Dec 31, 24 |
| 15 | T. Rowe Price Associates, Inc. | 1.24M (4.18%) | 642.13K Increased by +51.77% | Dec 31, 25 |
| 16 | Saturn V Capital Management LLC | 1.19M (4.00%) | 91.84K Increased by +7.75% | Jun 30, 25 |
| 17 | TANG CAPITAL MANAGEMENT LLC | 1.05M (3.54%) | -100.00K Decreased by -9.52% | Dec 31, 25 |
| 18 | Bank of America Corp | 977.12K (3.29%) | 437.59K Increased by +44.78% | Dec 31, 25 |
| 19 | VR Adviser, LLC | 970.00K (3.27%) | -1.14M Decreased by -117.05% | Mar 31, 24 |
| 20 | Balyasny Asset Management LLC | 937.79K (3.16%) | 55.85K Increased by +5.96% | Jun 30, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 1.34M (4.50%) | 7.48K Increased by +0.56% | Mar 31, 26 |
| 2 | Vanguard US Total Market Shares ETF | 1.00M (3.39%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 3 | iShares Russell 2000 ETF | 818.09K (2.76%) | -1.76K Decreased by -0.21% | Apr 29, 26 |
| 4 | State Street® SPDR® S&P® Biotech ETF | 815.95K (2.75%) | -8.07K Decreased by -0.99% | Apr 30, 26 |
| 5 | T. Rowe Price Health Sciences | 540.30K (1.82%) | -36.98K Decreased by -6.84% | Mar 31, 26 |
| 6 | Columbia Small Cap Value Discovery Fund | 523.74K (1.77%) | 208.46K Increased by +39.80% | Jun 30, 25 |
| 7 | Columbia Small Cap Value I | 523.74K (1.77%) | 208.46K Increased by +39.80% | Jun 30, 25 |
| 8 | Vanguard Institutional Extnd Mkt Idx Tr | 403.55K (1.36%) | 10.16K Increased by +2.52% | Mar 31, 26 |
| 9 | SPDR® S&P Biotech ETF | 327.79K (1.11%) | -2.00K Decreased by -0.61% | Feb 28, 25 |
| 10 | Fidelity Small Cap Index | 314.88K (1.06%) | 3.23K Increased by +1.03% | Feb 28, 26 |
| 11 | Eventide Healthcare & Life Sciences I | 312.58K (1.05%) | -776.13K Decreased by -248.29% | Dec 31, 25 |
| 12 | Belfius Equities Cure C Cap | 302.31K (1.02%) | -61.87K Decreased by -20.47% | Nov 30, 25 |
| 13 | Artisan International Small-Mid Investor | 283.25K (0.96%) | -48.35K Decreased by -17.07% | Mar 31, 26 |
| 14 | Artisan Non-U.S. Small-Mid Growth Comp | 283.25K (0.96%) | -48.35K Decreased by -17.07% | Mar 31, 26 |
| 15 | iShares Russell 2000 Growth ETF | 271.89K (0.92%) | 0.00 Increased by 0.00% | Apr 29, 26 |
| 16 | T. Rowe Price New Horizons | 246.07K (0.83%) | 22.47K Increased by +9.13% | Mar 31, 26 |
| 17 | US Small-Cap Growth II Equity Comp | 246.07K (0.83%) | 48.27K Increased by +19.62% | Mar 31, 26 |
| 18 | State St Russell Sm/Mid Cp® Indx SL Cl I | 208.87K (0.70%) | 22.70K Increased by +10.87% | Mar 31, 26 |
| 19 | Russell 2000 Equity Index Fund B | 199.28K (0.67%) | 8.70K Increased by +4.37% | Dec 31, 25 |
| 20 | Candriam Eqs L Biotech C USD Cap | 195.99K (0.66%) | 6.12K Increased by +3.12% | Oct 31, 25 |