| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Baker Bros Advisors LP | 5.45M (29.15%) | 1.19M Increased by +21.88% | Jun 30, 25 |
| 2 | Bvf Inc | 3.47M (18.54%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 3 | Soleus Capital Management, L.P. | 3.01M (16.11%) | 437.70K Increased by +14.53% | Jun 30, 25 |
| 4 | NEA Management Company, LLC | 2.29M (12.27%) | 1.04M Increased by +45.52% | Jun 30, 25 |
| 5 | BlackRock Inc | 2.07M (11.08%) | -141.91K Decreased by -6.85% | Jun 30, 25 |
| 6 | Vanguard Group Inc | 1.67M (8.92%) | -4.46K Decreased by -0.27% | Jun 30, 25 |
| 7 | Perceptive Advisors LLC | 1.63M (8.74%) | -729.07K Decreased by -44.64% | Jun 30, 25 |
| 8 | RA Capital Management, LLC | 1.40M (7.49%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 9 | Eventide Asset Management, LLC | 1.39M (7.43%) | 123.77K Increased by +8.91% | Jun 30, 25 |
| 10 | Samlyn Capital, LLC | 1.25M (6.69%) | -39.34K Decreased by -3.14% | Dec 31, 24 |
| 11 | Saturn V Capital Management LLC | 1.19M (6.34%) | 91.84K Increased by +7.75% | Jun 30, 25 |
| 12 | VR Adviser, LLC | 970.00K (5.19%) | -1.14M Decreased by -117.05% | Mar 31, 24 |
| 13 | Balyasny Asset Management LLC | 937.79K (5.02%) | 55.85K Increased by +5.96% | Jun 30, 24 |
| 14 | BRAIDWELL LP | 884.31K (4.73%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 15 | HHG PLC | 796.98K (4.26%) | 148.86K Increased by +18.68% | Mar 31, 25 |
| 16 | Morgan Stanley - Brokerage Accounts | 784.08K (4.19%) | -52.87K Decreased by -6.74% | Jun 30, 25 |
| 17 | Ameriprise Financial Inc | 768.80K (4.11%) | 166.32K Increased by +21.63% | Jun 30, 25 |
| 18 | Citadel Advisors Llc | 754.15K (4.03%) | -194.28K Decreased by -25.76% | Jun 30, 25 |
| 19 | Partner Fund Management LP | 710.25K (3.80%) | -126.75K Decreased by -17.85% | Sep 30, 24 |
| 20 | COMMODORE CAPITAL LP | 695.65K (3.72%) | 295.65K Increased by +42.50% | Mar 31, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Eventide Healthcare & Life Sciences I | 1.39M (7.43%) | 123.77K Increased by +8.91% | Jun 30, 25 |
| 2 | Vanguard Total Stock Mkt Idx Inv | 1.12M (6.01%) | 138.31K Increased by +12.32% | Jul 31, 25 |
| 3 | Vanguard US Total Market Shares ETF | 1.00M (5.38%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 4 | iShares Russell 2000 ETF | 708.27K (3.79%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 5 | Columbia Small Cap Value Discovery Fund | 523.74K (2.80%) | 208.46K Increased by +39.80% | Jun 30, 25 |
| 6 | Columbia Small Cap Value I | 523.74K (2.80%) | 208.46K Increased by +39.80% | Jun 30, 25 |
| 7 | Belfius Equities Cure C Cap | 402.28K (2.15%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 8 | SPDR® S&P Biotech ETF | 327.79K (1.75%) | -2.00K Decreased by -0.61% | Feb 28, 25 |
| 9 | Vanguard Institutional Extnd Mkt Idx Tr | 302.08K (1.62%) | -136.13K Decreased by -45.06% | Jul 31, 25 |
| 10 | Fidelity Small Cap Index | 287.99K (1.54%) | -42.94K Decreased by -14.91% | Jun 30, 25 |
| 11 | Artisan International Small-Mid Investor | 273.60K (1.46%) | -52.97K Decreased by -19.36% | Jun 30, 25 |
| 12 | Artisan Non-U.S. Small-Mid Growth Comp | 273.60K (1.46%) | -52.97K Decreased by -19.36% | Jun 30, 25 |
| 13 | iShares Russell 2000 Growth ETF | 241.44K (1.29%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 14 | AB Small Cap Growth A | 206.43K (1.10%) | 206.43K Increased by +100.00% | Jul 31, 25 |
| 15 | Candriam Eqs L Biotech C USD Cap | 192.89K (1.03%) | 192.89K Increased by +100.00% | Jul 31, 25 |
| 16 | Invesco Dorsey Wright SmallCap Momt ETF | 191.97K (1.03%) | 0.00 Increased by 0.00% | Apr 30, 24 |
| 17 | iShares Russell 2000 Value ETF | 167.14K (0.89%) | 0.00 Increased by 0.00% | Apr 30, 24 |
| 18 | State St Russell Sm/Mid Cp® Indx SL Cl I | 165.47K (0.89%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 19 | Fidelity® Small Cap Index | 164.64K (0.88%) | 1.34K Increased by +0.81% | Oct 31, 23 |
| 20 | State St Russell Sm/Mid Cp® Indx NL Cl C | 164.17K (0.88%) | 743.00 Increased by +0.45% | Apr 30, 25 |