| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Baker Bros Advisors LP | 4.26M (20.04%) | 1.58M Increased by +37.09% | Mar 31, 25 |
| 2 | Bvf Inc | 3.47M (16.31%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 3 | Soleus Capital Management, L.P. | 2.57M (12.12%) | 9.04K Increased by +0.35% | Mar 31, 25 |
| 4 | Perceptive Advisors LLC | 2.36M (11.12%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 5 | BlackRock Inc | 2.21M (10.41%) | 33.53K Increased by +1.52% | Mar 31, 25 |
| 6 | Vanguard Group Inc | 1.67M (7.87%) | 20.26K Increased by +1.21% | Mar 31, 25 |
| 7 | RA Capital Management, LLC | 1.40M (6.59%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 8 | Eventide Asset Management, LLC | 1.27M (5.96%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 9 | Samlyn Capital, LLC | 1.25M (5.89%) | -39.34K Decreased by -3.14% | Dec 31, 24 |
| 10 | NEA Management Company, LLC | 1.25M (5.88%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 11 | Saturn V Capital Management LLC | 1.09M (5.15%) | 29.89K Increased by +2.73% | Mar 31, 25 |
| 12 | VR Adviser, LLC | 970.00K (4.57%) | -1.14M Decreased by -117.05% | Mar 31, 24 |
| 13 | Citadel Advisors Llc | 948.43K (4.46%) | 112.41K Increased by +11.85% | Mar 31, 25 |
| 14 | Balyasny Asset Management LLC | 937.79K (4.41%) | 55.85K Increased by +5.96% | Jun 30, 24 |
| 15 | BRAIDWELL LP | 884.31K (4.16%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 16 | Morgan Stanley - Brokerage Accounts | 836.95K (3.94%) | -39.94K Decreased by -4.77% | Mar 31, 25 |
| 17 | HHG PLC | 796.98K (3.75%) | 148.86K Increased by +18.68% | Mar 31, 25 |
| 18 | Geode Capital Management, LLC | 719.92K (3.39%) | 27.55K Increased by +3.83% | Mar 31, 25 |
| 19 | Partner Fund Management LP | 710.25K (3.34%) | -126.75K Decreased by -17.85% | Sep 30, 24 |
| 20 | COMMODORE CAPITAL LP | 695.65K (3.27%) | 295.65K Increased by +42.50% | Mar 31, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Eventide Healthcare & Life Sciences I | 1.27M (5.96%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 2 | Vanguard US Total Market Shares ETF | 1.00M (4.73%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 3 | Vanguard Total Stock Mkt Idx Inv | 984.56K (4.63%) | 0.00 Increased by 0.00% | May 31, 25 |
| 4 | iShares Russell 2000 ETF | 740.99K (3.49%) | 5.17K Increased by +0.70% | Jun 30, 25 |
| 5 | Columbia Small Cap Value I A | 523.74K (2.47%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 6 | Vanguard Institutional Extnd Mkt Idx Tr | 435.35K (2.05%) | 5.56K Increased by +1.28% | May 31, 25 |
| 7 | Fidelity Small Cap Index | 334.71K (1.58%) | 9.21K Increased by +2.75% | Apr 30, 25 |
| 8 | SPDR® S&P Biotech ETF | 327.79K (1.54%) | -2.00K Decreased by -0.61% | Feb 28, 25 |
| 9 | Columbia Small Cap Value I | 315.28K (1.48%) | 18.50K Increased by +5.87% | Mar 31, 25 |
| 10 | Artisan International Small-Mid Investor | 273.60K (1.29%) | -52.97K Decreased by -19.36% | Jun 30, 25 |
| 11 | Artisan Non-U.S. Small-Mid Growth Comp | 273.60K (1.29%) | -52.97K Decreased by -19.36% | Jun 30, 25 |
| 12 | Belfius Equities Cure C Cap | 263.58K (1.24%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 13 | iShares Russell 2000 Growth ETF | 243.54K (1.15%) | 600.00 Increased by +0.25% | Jun 30, 25 |
| 14 | Invesco Dorsey Wright SmallCap Momt ETF | 191.97K (0.90%) | 0.00 Increased by 0.00% | Apr 30, 24 |
| 15 | iShares Russell 2000 Value ETF | 167.14K (0.79%) | 0.00 Increased by 0.00% | Apr 30, 24 |
| 16 | Vanguard Russell 2000 ETF | 165.82K (0.78%) | 1.48K Increased by +0.89% | May 31, 25 |
| 17 | State St Russell Sm/Mid Cp® Indx SL Cl I | 165.47K (0.78%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 18 | Fidelity® Small Cap Index | 164.64K (0.77%) | 1.34K Increased by +0.81% | Oct 31, 23 |
| 19 | State St Russell Sm/Mid Cp® Indx NL Cl C | 164.17K (0.77%) | 743.00 Increased by +0.45% | Apr 30, 25 |
| 20 | Fidelity Extended Market Index | 147.54K (0.69%) | -659.00 Decreased by -0.45% | May 31, 25 |