| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Opaleye Management Inc | 12.60M (18.42%) | 3.10M Increased by +24.60% | Jun 30, 25 |
| 2 | Casdin Capital, LLC | 7.20M (10.52%) | -900.00K Decreased by -12.50% | Jun 30, 25 |
| 3 | BlackRock Inc | 7.14M (10.43%) | -448.85K Decreased by -6.29% | Jun 30, 25 |
| 4 | FMR Inc | 4.61M (6.74%) | 40.93K Increased by +0.89% | Jun 30, 25 |
| 5 | Vanguard Group Inc | 4.59M (6.71%) | -135.73K Decreased by -2.96% | Jun 30, 25 |
| 6 | Aberdeen Group PLC | 4.20M (6.14%) | 3.59M Increased by +85.57% | Jun 30, 25 |
| 7 | Nantahala Capital Management, LLC | 4.03M (5.89%) | 1.20M Increased by +29.77% | Jun 30, 25 |
| 8 | Telemark Asset Management, LLC | 4.00M (5.85%) | 1.00M Increased by +25.00% | Jun 30, 25 |
| 9 | Ameriprise Financial Inc | 2.55M (3.73%) | 16.10K Increased by +0.63% | Jun 30, 25 |
| 10 | Geode Capital Management, LLC | 1.98M (2.89%) | 52.59K Increased by +2.66% | Jun 30, 25 |
| 11 | Pier Capital, LLC | 1.92M (2.80%) | 245.96K Increased by +12.84% | Jun 30, 25 |
| 12 | Nuveen Asset Management, LLC | 1.81M (2.65%) | 283.76K Increased by +15.66% | Dec 31, 24 |
| 13 | Baillie Gifford & Co Limited. | 1.69M (2.46%) | -13.98K Decreased by -0.83% | Jun 30, 25 |
| 14 | State Street Corp | 1.61M (2.36%) | -33.90K Decreased by -2.10% | Jun 30, 25 |
| 15 | D. E. Shaw & Co LP | 1.60M (2.34%) | -275.51K Decreased by -17.21% | Sep 30, 23 |
| 16 | State Street Corporation | 1.51M (2.21%) | 26.05K Increased by +1.72% | Mar 31, 24 |
| 17 | Millennium Management LLC | 1.40M (2.05%) | 1.33M Increased by +94.86% | Sep 30, 24 |
| 18 | Kent Lake Capital LLC | 1.30M (1.90%) | 670.60K Increased by +51.58% | Jun 30, 24 |
| 19 | Nuveen, LLC | 1.25M (1.82%) | 1.25M Increased by +100.00% | Mar 31, 25 |
| 20 | Jacobs Levy Equity Management, Inc. | 1.18M (1.72%) | 107.88K Increased by +9.16% | Jun 30, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | abrdn Healthcare Investors | 2.50M (3.66%) | 160.82K Increased by +6.42% | Aug 31, 25 |
| 2 | Vanguard Total Stock Mkt Idx Inv | 2.37M (3.47%) | -52.35K Decreased by -2.21% | Jul 31, 25 |
| 3 | Vanguard US Total Market Shares ETF | 2.08M (3.03%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 4 | iShares Russell 2000 ETF | 1.99M (2.91%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 5 | Columbia Small Cap Value Discv A | 1.70M (2.48%) | 46.70K Increased by +2.75% | Jul 31, 25 |
| 6 | Columbia Small Cap Value I A | 1.70M (2.48%) | 46.70K Increased by +2.75% | Jul 31, 25 |
| 7 | Columbia Small Cap Value Discovery Fund | 1.65M (2.41%) | -3.96K Decreased by -0.24% | Jun 30, 25 |
| 8 | Columbia Small Cap Value I | 1.65M (2.41%) | -3.96K Decreased by -0.24% | Jun 30, 25 |
| 9 | abrdn Life Sciences Investors | 1.59M (2.32%) | 72.55K Increased by +4.57% | Aug 31, 25 |
| 10 | Fidelity VIP Growth Initial | 1.14M (1.67%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 11 | VIP Growth Initial | 1.14M (1.67%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 12 | Fidelity Advisor® Equity Growth I | 1.12M (1.64%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 13 | Fidelity Advisor Equity Growth I | 1.12M (1.64%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 14 | Edinburgh Worldwide Ord | 1.04M (1.52%) | 0.00 Increased by 0.00% | Aug 31, 24 |
| 15 | Fidelity Capital Appreciation | 970.51K (1.42%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 16 | Fidelity® Capital Appreciation | 970.51K (1.42%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 17 | Vanguard Institutional Extnd Mkt Idx Tr | 886.96K (1.30%) | -404.16K Decreased by -45.57% | Jul 31, 25 |
| 18 | Fidelity Small Cap Index | 815.42K (1.19%) | -583.00 Decreased by -0.07% | Jun 30, 25 |
| 19 | Paradigm Micro-Cap | 800.00K (1.17%) | 0.00 Increased by 0.00% | Jun 30, 24 |
| 20 | Old Westbury Small & Mid Cap Strategies | 745.38K (1.09%) | 0.00 Increased by 0.00% | Apr 30, 24 |