| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | RA Capital Management, LLC | 8.00M (11.98%) | 8.00M Increased by +100.00% | Dec 31, 25 |
| 2 | Bain Capital Life Sciences Investors, LLC | 7.17M (10.74%) | 6.06M Increased by +84.50% | Dec 31, 25 |
| 3 | State Street Corporation | 7.15M (10.71%) | 7.00M Increased by +97.83% | Mar 31, 24 |
| 4 | Lynx1 Capital Management, LP | 7.10M (10.63%) | 0.00 Increased by 0.00% | Sep 30, 25 |
| 5 | Soleus Capital Management, L.P. | 7.05M (10.56%) | 75.00K Increased by +1.06% | Sep 30, 25 |
| 6 | Wasatch Advisors Inc. | 6.25M (9.36%) | -952.35K Decreased by -15.24% | Sep 30, 23 |
| 7 | Morgan Stanley - Brokerage Accounts | 4.97M (7.45%) | 217.84K Increased by +4.38% | Sep 30, 25 |
| 8 | Vanguard Group Inc | 4.38M (6.56%) | 1.19M Increased by +27.13% | Dec 31, 25 |
| 9 | Wasatch Advisors LP | 4.34M (6.51%) | -507.82K Decreased by -11.69% | Dec 31, 25 |
| 10 | COMMODORE CAPITAL LP | 3.41M (5.11%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 11 | Samlyn Capital, LLC | 3.02M (4.52%) | -4.32K Decreased by -0.14% | Mar 31, 25 |
| 12 | T. Rowe Price Associates, Inc. | 2.12M (3.17%) | -443.00K Decreased by -20.94% | Mar 31, 24 |
| 13 | Bank of America Corp | 2.05M (3.07%) | 45.16K Increased by +2.20% | Sep 30, 25 |
| 14 | SILVERARC CAPITAL MANAGEMENT, LLC | 1.99M (2.99%) | 96.84K Increased by +4.86% | Dec 31, 25 |
| 15 | Aquilo Capital Management, LLC | 1.99M (2.98%) | 1.23M Increased by +61.78% | Sep 30, 23 |
| 16 | Balyasny Asset Management LLC | 1.94M (2.90%) | -499.24K Decreased by -25.79% | Jun 30, 24 |
| 17 | Susquehanna International Group, LLP | 1.78M (2.66%) | 1.26M Increased by +70.97% | Dec 31, 25 |
| 18 | Renaissance Technologies Corp | 1.60M (2.40%) | 665.63K Increased by +41.53% | Dec 31, 25 |
| 19 | BlackRock Inc | 1.60M (2.39%) | -232.97K Decreased by -14.60% | Sep 30, 25 |
| 20 | Adage Capital Partners Gp LLC | 1.55M (2.32%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 2.89M (4.33%) | 0.00 Increased by 0.00% | Jan 31, 26 |
| 2 | Wasatch Ultra Growth | 2.83M (4.23%) | -289.22K Decreased by -10.23% | Dec 31, 25 |
| 3 | Vanguard US Total Market Shares ETF | 2.14M (3.20%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 4 | SPDR® S&P Biotech ETF | 1.58M (2.36%) | -47.88K Decreased by -3.04% | Nov 27, 24 |
| 5 | iShares Russell 2000 ETF | 1.53M (2.29%) | 0.00 Increased by 0.00% | May 31, 25 |
| 6 | T. Rowe Price New Horizons | 1.16M (1.74%) | -241.79K Decreased by -20.77% | Mar 31, 24 |
| 7 | US Small-Cap Growth II Equity Comp | 1.16M (1.74%) | -241.79K Decreased by -20.77% | Mar 31, 24 |
| 8 | Wasatch Small Cap Value | 1.03M (1.55%) | 191.80K Increased by +18.59% | Dec 31, 23 |
| 9 | Vanguard Institutional Extnd Mkt Idx Tr | 882.93K (1.32%) | 0.00 Increased by 0.00% | Jan 31, 26 |
| 10 | Biotech Growth Ord | 770.91K (1.15%) | -471.81K Decreased by -61.20% | Nov 30, 25 |
| 11 | Wasatch Micro Cap | 758.27K (1.14%) | -483.88K Decreased by -63.81% | Dec 31, 24 |
| 12 | Fidelity Small Cap Index | 623.59K (0.93%) | -8.75K Decreased by -1.40% | May 31, 25 |
| 13 | Invesco Dorsey Wright Healthcare MomtETF | 598.21K (0.90%) | 5.31K Increased by +0.89% | Jan 31, 24 |
| 14 | iShares Biotechnology ETF | 583.12K (0.87%) | 0.00 Increased by 0.00% | Feb 28, 26 |
| 15 | iShares Russell 2000 Value ETF | 560.98K (0.84%) | 0.00 Increased by 0.00% | May 31, 25 |
| 16 | ArrowMark Small Cap Gro | 481.88K (0.72%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 17 | Meridian Small Cap Growth Legacy | 481.88K (0.72%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 18 | Fidelity Extended Market Index | 422.10K (0.63%) | -1.75K Decreased by -0.42% | Jan 31, 26 |
| 19 | International Biotechnology Ord | 405.88K (0.61%) | 0.00 Increased by 0.00% | Jun 30, 24 |
| 20 | Schwab US Small-Cap ETF™ | 383.14K (0.57%) | 336.00 Increased by +0.09% | Feb 28, 26 |