| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Suvretta Capital Management, LLC | 3.82M (7.87%) | 2.03M Increased by +53.24% | Mar 31, 26 |
| 2 | BlackRock Inc | 3.42M (7.05%) | 570.84K Increased by +16.68% | Mar 31, 26 |
| 3 | TANG CAPITAL MANAGEMENT LLC | 3.40M (7.00%) | 1.70M Increased by +50.00% | Mar 31, 26 |
| 4 | Highbridge Capital Management, LLC | 2.79M (5.75%) | 2.79M Increased by +100.00% | Sep 30, 23 |
| 5 | Vanguard Group Inc | 2.56M (5.28%) | 355.16K Increased by +13.86% | Dec 31, 25 |
| 6 | Farallon Capital Management, L.L.C. | 2.25M (4.64%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 7 | State Street Corp | 2.18M (4.49%) | 1.35M Increased by +61.98% | Mar 31, 26 |
| 8 | Vanguard Capital Management, LLC | 2.03M (4.18%) | 2.03M Increased by +100.00% | Mar 31, 26 |
| 9 | RA Capital Management, LLC | 1.51M (3.11%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 10 | Geode Capital Management, LLC | 1.12M (2.30%) | 100.99K Increased by +9.03% | Mar 31, 26 |
| 11 | The Goldman Sachs Group Inc | 911.98K (1.88%) | 463.99K Increased by +50.88% | Mar 31, 26 |
| 12 | Jones Hill Capital LP | 909.21K (1.87%) | 909.21K Increased by +100.00% | Mar 31, 26 |
| 13 | Point72 Asset Management, L.P. | 821.18K (1.69%) | -1.02M Decreased by -124.05% | Mar 31, 26 |
| 14 | Darwin Global Management, Ltd. | 800.00K (1.65%) | 800.00K Increased by +100.00% | Dec 31, 25 |
| 15 | FMR Inc | 772.65K (1.59%) | -149.99K Decreased by -19.41% | Mar 31, 26 |
| 16 | Altium Capital Management, LP | 714.00K (1.47%) | 429.00K Increased by +60.08% | Dec 31, 24 |
| 17 | Millennium Management LLC | 682.34K (1.41%) | 479.88K Increased by +70.33% | Dec 31, 25 |
| 18 | Soleus Capital Management, L.P. | 646.39K (1.33%) | 646.39K Increased by +100.00% | Dec 31, 25 |
| 19 | Boxer Capital Management, LLC | 590.00K (1.22%) | 265.00K Increased by +44.92% | Mar 31, 26 |
| 20 | Jane Street Group LLC | 566.08K (1.17%) | 566.08K Increased by +100.00% | Mar 31, 26 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 1.49M (3.07%) | 24.87K Increased by +1.67% | Apr 30, 26 |
| 2 | State Street® SPDR® S&P® Biotech ETF | 1.30M (2.67%) | -7.98K Decreased by -0.62% | May 31, 26 |
| 3 | iShares Russell 2000 ETF | 1.04M (2.14%) | 9.62K Increased by +0.93% | May 29, 26 |
| 4 | Vanguard US Total Market Shares ETF | 872.18K (1.80%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 5 | SPDR® S&P Biotech ETF | 584.18K (1.20%) | 1.30K Increased by +0.22% | Aug 31, 25 |
| 6 | Vanguard Institutional Extnd Mkt Idx Tr | 519.07K (1.07%) | 4.71K Increased by +0.91% | Apr 30, 26 |
| 7 | Fidelity Small Cap Index | 427.33K (0.88%) | 50.45K Increased by +11.81% | Mar 31, 26 |
| 8 | iShares Russell 2000 Growth ETF | 357.89K (0.74%) | -2.33K Decreased by -0.65% | May 29, 26 |
| 9 | Fidelity Select Biotechnology | 334.20K (0.69%) | 19.50K Increased by +5.83% | Apr 30, 26 |
| 10 | State St Russell Sm/Mid Cp® Indx SL Cl I | 263.73K (0.54%) | 0.00 Increased by 0.00% | May 31, 26 |
| 11 | Fidelity Extended Market Index | 243.76K (0.50%) | -890.00 Decreased by -0.37% | Apr 30, 26 |
| 12 | Russell 2000 Equity Index Fund B | 238.02K (0.49%) | -14.03K Decreased by -5.90% | Dec 31, 25 |
| 13 | Fidelity Select Pharmaceuticals Port | 231.30K (0.48%) | 0.00 Increased by 0.00% | Apr 30, 26 |
| 14 | State St Russell Sm/Mid Cp® Indx NL Cl C | 227.13K (0.47%) | 1.15K Increased by +0.51% | Apr 30, 25 |
| 15 | Vanguard Russell 2000 ETF | 220.30K (0.45%) | 5.75K Increased by +2.61% | Apr 30, 26 |
| 16 | Strategic Advisers Fidelity US TtlStk | 190.17K (0.39%) | 0.00 Increased by 0.00% | Apr 30, 26 |
| 17 | JPM Thmtcs Gentc Thrps C2 dist USD | 180.45K (0.37%) | 1.05K Increased by +0.58% | Apr 30, 26 |
| 18 | JPM Thematics Genetic Thrps C2 dist USD | 179.39K (0.37%) | -8.66K Decreased by -4.83% | Mar 31, 26 |
| 19 | SEB Nordamerikafond Småbolag | 179.36K (0.37%) | 50.51K Increased by +28.16% | Jul 31, 25 |
| 20 | Eastern Shore Small Cap Equity | 150.36K (0.31%) | -970.00 Decreased by -0.65% | Mar 31, 26 |