| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | T. Rowe Price Investment Management,Inc. | 3.97M (6.53%) | -103.98K Decreased by -2.62% | Mar 31, 25 |
| 2 | State Street Corporation | 3.74M (6.16%) | 1.15M Increased by +30.66% | Mar 31, 24 |
| 3 | Adage Capital Partners Gp LLC | 3.63M (5.98%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 4 | BlackRock Inc | 3.45M (5.68%) | 54.89K Increased by +1.59% | Mar 31, 25 |
| 5 | Vanguard Group Inc | 2.84M (4.68%) | -23.48K Decreased by -0.83% | Mar 31, 25 |
| 6 | Bain Capital Life Sciences Investors, LLC | 2.76M (4.54%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 7 | Alkeon Capital Management, LLC | 2.62M (4.31%) | 2.12M Increased by +80.90% | Jun 30, 24 |
| 8 | Jennison Associates LLC | 2.43M (4.00%) | -78.33K Decreased by -3.22% | Mar 31, 25 |
| 9 | Redmile Group, LLC | 1.77M (2.92%) | 403.95K Increased by +22.77% | Sep 30, 23 |
| 10 | Morgan Stanley - Brokerage Accounts | 1.71M (2.81%) | 269.72K Increased by +15.78% | Mar 31, 25 |
| 11 | Schonfeld Strategic Advisors LLC | 1.66M (2.74%) | 1.66M Increased by +100.00% | Mar 31, 25 |
| 12 | Baker Bros Advisors LP | 1.59M (2.62%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 13 | VR Adviser, LLC | 1.56M (2.57%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 14 | Sofinnova Ventures | 1.53M (2.52%) | 313.48K Increased by +20.44% | Sep 30, 24 |
| 15 | StemPoint Capital LP | 1.28M (2.10%) | 100.34K Increased by +7.85% | Sep 30, 24 |
| 16 | Point72 Asset Management, L.P. | 1.27M (2.08%) | 598.61K Increased by +47.29% | Dec 31, 24 |
| 17 | Polar Capital Holdings PLC | 1.25M (2.06%) | 3.50K Increased by +0.28% | Jun 30, 24 |
| 18 | Holocene Advisors, LP | 1.18M (1.95%) | 1.18M Increased by +100.00% | Sep 30, 23 |
| 19 | Geode Capital Management, LLC | 1.14M (1.88%) | 30.59K Increased by +2.68% | Mar 31, 25 |
| 20 | COMMODORE CAPITAL LP | 1.10M (1.81%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | T. Rowe Price Small-Cap Value | 3.56M (5.87%) | 1.64M Increased by +45.92% | Jun 30, 25 |
| 2 | Jennison Health Sciences Equity | 3.52M (5.79%) | 2.14M Increased by +60.81% | Jun 30, 25 |
| 3 | PGIM Jennison Health Sciences Z | 3.52M (5.79%) | 2.14M Increased by +60.81% | Jun 30, 25 |
| 4 | Vanguard Total Stock Mkt Idx Inv | 2.62M (4.30%) | 1.21M Increased by +46.43% | Jun 30, 25 |
| 5 | T. Rowe Price U.S. SC Value Eq Tr-D | 2.10M (3.46%) | 1.04M Increased by +49.37% | Jun 30, 25 |
| 6 | T. Rowe Price Health Sciences | 1.94M (3.20%) | 1.63M Increased by +83.88% | Jun 30, 25 |
| 7 | Vanguard US Total Market Shares ETF | 1.40M (2.31%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 8 | Jennison SMid Cap Core Equity | 1.29M (2.12%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 9 | PGIM Jennison Small Company A | 1.29M (2.12%) | 0.00 Increased by 0.00% | Oct 31, 24 |
| 10 | Polar Capital Biotech S Inc | 1.25M (2.06%) | 0.00 Increased by 0.00% | Jul 31, 24 |
| 11 | iShares Russell 2000 ETF | 1.17M (1.93%) | 0.00 Increased by 0.00% | May 31, 25 |
| 12 | SPDR® S&P Biotech ETF | 1.13M (1.86%) | 3.92K Increased by +0.35% | Aug 30, 24 |
| 13 | Alger Small Cap Focus Composite | 1.08M (1.77%) | -561.71K Decreased by -52.18% | Jan 31, 25 |
| 14 | Alger Small Cap Focus I | 1.08M (1.77%) | -561.71K Decreased by -52.18% | Jan 31, 25 |
| 15 | T. Rowe Price U.S. SC Value Eq Tr-Z | 1.06M (1.75%) | 1.82K Increased by +0.17% | Mar 31, 25 |
| 16 | UBS: US Equity Small Cap Growth | 959.98K (1.58%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 17 | T. Rowe Price US Smlr Coms Eq A | 801.75K (1.32%) | 166.69K Increased by +20.79% | Jun 30, 25 |
| 18 | T. Rowe Price US Smlr Cm Eq A USD | 714.39K (1.18%) | -36.66K Decreased by -5.13% | Apr 30, 25 |
| 19 | Vanguard Institutional Extnd Mkt Idx Tr | 712.91K (1.17%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 20 | T. Rowe Price Small-Cap Stock | 675.76K (1.11%) | 61.28K Increased by +9.07% | Jun 30, 24 |