| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Suvretta Capital Management, LLC | 11.55M (64.79%) | 1.67M Increased by +14.48% | Dec 31, 25 |
| 2 | HHG PLC | 2.91M (16.33%) | 8.89K Increased by +0.31% | Sep 30, 25 |
| 3 | Franklin Resources Inc | 2.59M (14.53%) | -111.81K Decreased by -4.32% | Sep 30, 25 |
| 4 | Adage Capital Partners Gp LLC | 2.12M (11.90%) | 148.15K Increased by +6.99% | Dec 31, 25 |
| 5 | RA Capital Management, LLC | 1.85M (10.38%) | 1.85M Increased by +100.00% | Dec 31, 25 |
| 6 | Vanguard Group Inc | 1.17M (6.59%) | 182.64K Increased by +15.55% | Dec 31, 25 |
| 7 | Nantahala Capital Management, LLC | 1.04M (5.83%) | 200.28K Increased by +19.29% | Dec 31, 25 |
| 8 | BlackRock Inc | 945.51K (5.30%) | 226.82K Increased by +23.99% | Sep 30, 25 |
| 9 | Siren, L.L.C. | 775.00K (4.35%) | 775.00K Increased by +100.00% | Dec 31, 25 |
| 10 | Alyeska Investment Group, L.P. | 750.00K (4.21%) | 750.00K Increased by +100.00% | Dec 31, 25 |
| 11 | SILVERARC CAPITAL MANAGEMENT, LLC | 731.72K (4.10%) | 455.45K Increased by +62.24% | Dec 31, 25 |
| 12 | Balyasny Asset Management LLC | 651.56K (3.66%) | 651.56K Increased by +100.00% | Dec 31, 25 |
| 13 | Millennium Management LLC | 613.16K (3.44%) | 613.16K Increased by +100.00% | Dec 31, 25 |
| 14 | Geode Capital Management, LLC | 453.38K (2.54%) | 14.87K Increased by +3.28% | Dec 31, 25 |
| 15 | Awm Investment Company Inc | 282.98K (1.59%) | 100.00K Increased by +35.34% | Dec 31, 25 |
| 16 | Schonfeld Strategic Advisors LLC | 262.20K (1.47%) | 1.79K Increased by +0.68% | Dec 31, 25 |
| 17 | Susquehanna International Group, LLP | 226.10K (1.27%) | 201.32K Increased by +89.04% | Mar 31, 25 |
| 18 | MYDA Advisors LLC | 225.00K (1.26%) | 155.00K Increased by +68.89% | Dec 31, 25 |
| 19 | State Street Corp | 218.40K (1.23%) | 57.33K Increased by +26.25% | Sep 30, 25 |
| 20 | The Goldman Sachs Group Inc | 194.36K (1.09%) | 173.37K Increased by +89.20% | Sep 30, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Franklin Biotechnology Discv A(acc)USD | 1.20M (6.74%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 2 | HBM Healthcare Investments AG Ord | 1.19M (6.69%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 3 | Franklin Biotechnology Discovery A | 995.15K (5.58%) | 0.00 Increased by 0.00% | Jan 31, 26 |
| 4 | Vanguard Total Stock Mkt Idx Inv | 627.79K (3.52%) | 0.00 Increased by 0.00% | Jan 31, 26 |
| 5 | Janus Henderson Hrzn Biotec E2 USD | 433.14K (2.43%) | 8.89K Increased by +2.05% | Dec 31, 25 |
| 6 | iShares Russell 2000 ETF | 347.81K (1.95%) | 347.81K Increased by +100.00% | Feb 28, 26 |
| 7 | Simplify Health Care ETF | 328.38K (1.84%) | 0.00 Increased by 0.00% | Feb 27, 26 |
| 8 | Vanguard Institutional Extnd Mkt Idx Tr | 272.51K (1.53%) | 0.00 Increased by 0.00% | Jan 31, 26 |
| 9 | MEDICAL BioHealth EUR Acc | 195.25K (1.10%) | 75.02K Increased by +38.42% | Jan 31, 26 |
| 10 | Fidelity Small Cap Index | 146.23K (0.82%) | -3.32K Decreased by -2.27% | Dec 31, 25 |
| 11 | Fidelity Extended Market Index | 130.90K (0.73%) | -543.00 Decreased by -0.41% | Jan 31, 26 |
| 12 | iShares Russell 2000 Growth ETF | 128.77K (0.72%) | 128.77K Increased by +100.00% | Feb 28, 26 |
| 13 | Franklin Small Cap Growth Adv | 75.97K (0.43%) | 75.97K Increased by +100.00% | Jan 31, 26 |
| 14 | Vanguard Russell 2000 ETF | 70.77K (0.40%) | -2.46K Decreased by -3.48% | Jan 31, 26 |
| 15 | Blackrock Extended Mkt Fund CF | 67.50K (0.38%) | 67.50K Increased by +100.00% | Jan 31, 26 |
| 16 | Extended Equity Market Fund K | 57.89K (0.32%) | 38.00 Increased by +0.07% | Dec 31, 25 |
| 17 | RIM Global Bioscience EUR | 52.66K (0.30%) | 9.60K Increased by +18.23% | Nov 30, 25 |
| 18 | State St Russell Sm Cap® Indx SL Cl I | 50.80K (0.28%) | 0.00 Increased by 0.00% | Feb 28, 26 |
| 19 | Fidelity Total Market Index | 42.30K (0.24%) | 0.00 Increased by 0.00% | Jan 31, 26 |
| 20 | IMC US Ultra Micro Cap | 40.38K (0.23%) | -3.04K Decreased by -7.53% | Jun 30, 25 |