| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | FMR Inc | 8.81M (13.07%) | 1.20M Increased by +13.58% | Dec 31, 25 |
| 2 | Heights Capital Management Inc | 3.84M (5.69%) | 3.84M Increased by +100.00% | Jun 30, 25 |
| 3 | Cormorant Asset Management, LLC | 3.57M (5.29%) | 0.00 Increased by 0.00% | Sep 30, 25 |
| 4 | Vanguard Group Inc | 2.97M (4.40%) | 797.98K Increased by +26.89% | Dec 31, 25 |
| 5 | LAURION CAPITAL MANAGEMENT LP | 2.61M (3.87%) | 369.45K Increased by +14.14% | Sep 30, 23 |
| 6 | Aisling Capital Management LP | 2.05M (3.04%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 7 | HHG PLC | 1.72M (2.55%) | -1.26M Decreased by -73.29% | Dec 31, 23 |
| 8 | Baker Bros Advisors LP | 1.45M (2.15%) | -656.96K Decreased by -45.25% | Dec 31, 24 |
| 9 | State Street Corporation | 1.35M (2.00%) | -947.72K Decreased by -70.15% | Dec 31, 23 |
| 10 | Woodline Partners LP | 1.30M (1.93%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 11 | Blue Owl Capital Holdings LP | 1.30M (1.93%) | 1.30M Increased by +100.00% | Jun 30, 25 |
| 12 | Driehaus Capital Management LLC | 1.18M (1.75%) | 269.88K Increased by +22.82% | Dec 31, 23 |
| 13 | Marshall Wace Asset Management Ltd | 1.16M (1.72%) | 865.62K Increased by +74.60% | Dec 31, 25 |
| 14 | BlackRock Inc | 901.55K (1.34%) | 148.00K Increased by +16.42% | Sep 30, 25 |
| 15 | Perceptive Advisors LLC | 716.44K (1.06%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 16 | Fideuram - Intesa Sanpaolo Private Banking Spa | 631.47K (0.94%) | 631.47K Increased by +100.00% | Dec 31, 25 |
| 17 | Mariner Wealth Advisors LLC | 585.63K (0.87%) | 346.70K Increased by +59.20% | Dec 31, 25 |
| 18 | Federated Hermes Inc | 572.04K (0.85%) | -4.32K Decreased by -0.76% | Sep 30, 25 |
| 19 | Geode Capital Management, LLC | 562.90K (0.83%) | 116.02K Increased by +20.61% | Dec 31, 25 |
| 20 | Adage Capital Partners Gp LLC | 500.00K (0.74%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | SPDR® S&P Biotech ETF | 4.01M (5.94%) | 21.37K Increased by +0.53% | Mar 31, 24 |
| 2 | Fidelity Growth Compy Commingled Pl S | 3.93M (5.82%) | 0.00 Increased by 0.00% | Feb 28, 26 |
| 3 | Fidelity Growth Company Fund | 2.71M (4.02%) | 0.00 Increased by 0.00% | Feb 28, 26 |
| 4 | Fidelity Growth Compy Commingled Pl O | 2.19M (3.25%) | 0.00 Increased by 0.00% | Feb 29, 24 |
| 5 | Vanguard Total Stock Mkt Idx Inv | 1.89M (2.80%) | 0.00 Increased by 0.00% | Feb 28, 26 |
| 6 | Fidelity® Growth Company | 1.65M (2.44%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 7 | Fidelity Growth Company K6 | 918.98K (1.36%) | 0.00 Increased by 0.00% | Feb 28, 26 |
| 8 | Fidelity Series Growth Company | 804.70K (1.19%) | 0.00 Increased by 0.00% | Feb 28, 26 |
| 9 | Vanguard US Total Market Shares ETF | 711.77K (1.06%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 10 | Fidelity® Growth Company K6 | 664.99K (0.99%) | -12.67K Decreased by -1.90% | Nov 30, 23 |
| 11 | Vanguard Institutional Extnd Mkt Idx Tr | 636.37K (0.94%) | 0.00 Increased by 0.00% | Feb 28, 26 |
| 12 | Janus Henderson Global Life Sciences | 563.57K (0.84%) | -302.98K Decreased by -53.76% | Dec 31, 23 |
| 13 | Janus Henderson Global Life Sciences D | 557.87K (0.83%) | -5.71K Decreased by -1.02% | Feb 29, 24 |
| 14 | Fidelity® Series Growth Company | 512.83K (0.76%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 15 | Direxion Daily S&P Biotech Bull 3X ETF | 478.37K (0.71%) | -3.36K Decreased by -0.70% | Mar 31, 24 |
| 16 | Fidelity Select Biotechnology | 452.66K (0.67%) | 0.00 Increased by 0.00% | Feb 28, 26 |
| 17 | Janus Henderson Glb Life Scn I2 USD | 431.18K (0.64%) | 3.79K Increased by +0.88% | Feb 29, 24 |
| 18 | Janus Selection Global Life Science AUSD | 426.15K (0.63%) | -252.20K Decreased by -59.18% | Dec 31, 23 |
| 19 | Fidelity® Select Biotechnology | 392.83K (0.58%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 20 | iShares Biotechnology ETF | 295.60K (0.44%) | 0.00 Increased by 0.00% | Aug 31, 25 |