| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Granahan Investment Management Inc.. | 7.71M (79.31%) | -366.03K Decreased by -4.75% | Mar 31, 24 |
| 2 | Ameriprise Financial Inc | 6.39M (65.73%) | -561.00 Decreased by -0.01% | Jun 30, 24 |
| 3 | Pictet Asset Manangement SA | 5.69M (58.49%) | 539.78K Increased by +9.49% | Dec 31, 23 |
| 4 | NORGES BANK | 4.00M (41.09%) | 3.96M Increased by +99.06% | Dec 31, 23 |
| 5 | State Street Corporation | 3.43M (35.26%) | -10.44M Decreased by -304.47% | Mar 31, 24 |
| 6 | Ghisallo Capital Management LLC | 3.15M (32.40%) | 3.15M Increased by +100.00% | Dec 31, 23 |
| 7 | TANG CAPITAL MANAGEMENT LLC | 2.50M (25.71%) | -1.78M Decreased by -71.31% | Mar 31, 24 |
| 8 | Baker Bros Advisors LP | 2.50M (25.71%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 9 | Hudson Bay Capital Management LP | 2.18M (22.46%) | 1.53M Increased by +70.00% | Dec 31, 23 |
| 10 | Vestal Point Capital LP | 2.15M (22.11%) | 2.15M Increased by +100.00% | Dec 31, 23 |
| 11 | Farallon Capital Management, L.L.C. | 2.00M (20.57%) | 2.00M Increased by +100.00% | Dec 31, 23 |
| 12 | Jacobs Levy Equity Management, Inc. | 1.84M (18.94%) | -249.33K Decreased by -13.54% | Sep 30, 23 |
| 13 | Credit Suisse First Boston (CSFB) | 1.78M (18.35%) | -67.13K Decreased by -3.76% | Sep 30, 23 |
| 14 | Dimensional Fund Advisors, Inc. | 1.65M (16.94%) | -1.35M Decreased by -81.80% | Mar 31, 24 |
| 15 | Millennium Management LLC | 1.61M (16.55%) | -3.54M Decreased by -219.91% | Sep 30, 24 |
| 16 | Rafferty Asset Management, LLC | 1.49M (15.34%) | -346.05K Decreased by -23.20% | Sep 30, 23 |
| 17 | Contrarius Investment Management Ltd | 1.31M (13.45%) | 1.31M Increased by +100.00% | Sep 30, 23 |
| 18 | ExodusPoint Capital Management, LP | 1.30M (13.34%) | 1.30M Increased by +100.00% | Sep 30, 24 |
| 19 | Alyeska Investment Group, L.P. | 1.26M (12.92%) | 1.26M Increased by +100.00% | Mar 31, 24 |
| 20 | Deutsche Bank AG | 1.17M (12.07%) | 443.24K Increased by +37.77% | Jun 30, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | SPDR® S&P Biotech ETF | 12.26M (126.10%) | 229.08K Increased by +1.87% | Feb 29, 24 |
| 2 | Columbia Acorn Inst | 5.37M (55.19%) | 0.00 Increased by 0.00% | Jul 31, 24 |
| 3 | Pictet Biopharmaceutical Mother | 2.63M (27.07%) | 1.06M Increased by +40.15% | Oct 13, 23 |
| 4 | Fidelity Select Pharmaceuticals Port | 2.23M (22.89%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 5 | M&G (ACS) Granahan US Sm Cp Gr GBPZ1AAcc | 1.81M (18.60%) | 86.07K Increased by +4.76% | Jan 31, 24 |
| 6 | JNL Multi-Manager Small Cap Growth A | 1.79M (18.38%) | -319.50K Decreased by -17.87% | Mar 31, 24 |
| 7 | CS (Lux) Digital Health Equity SB USD | 1.50M (15.43%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 8 | iShares Biotechnology ETF | 1.26M (12.94%) | 0.00 Increased by 0.00% | Nov 30, 24 |
| 9 | Granahan US SMID Select I GBP Acc | 1.21M (12.47%) | 7.68K Increased by +0.63% | Feb 29, 24 |
| 10 | Direxion Daily S&P Biotech Bull 3X ETF | 1.12M (11.54%) | 0.00 Increased by 0.00% | Feb 29, 24 |
| 11 | Contrarius Global Equity Investor | 1.10M (11.30%) | -89.09K Decreased by -8.11% | Dec 31, 23 |
| 12 | Fidelity® Small Cap Index | 1.03M (10.55%) | 20.61K Increased by +2.01% | Oct 31, 23 |
| 13 | Victory Small Cap Stock | 1.02M (10.47%) | 83.81K Increased by +8.23% | Mar 31, 24 |
| 14 | Wanger Acorn | 1.02M (10.46%) | 0.00 Increased by 0.00% | Jul 31, 24 |
| 15 | Granahan Inv Mgt Sm-Cap Core Gr | 1.02M (10.46%) | 83.02K Increased by +8.16% | Mar 31, 24 |
| 16 | Granahan SMID Select | 1.00M (10.32%) | -194.65K Decreased by -19.40% | Mar 31, 24 |
| 17 | Multi-Manager Small Cap Eq Strat Inst | 883.02K (9.08%) | 0.00 Increased by 0.00% | Aug 31, 24 |
| 18 | DWS Global Small Cap S | 796.49K (8.19%) | 0.00 Increased by 0.00% | Jul 31, 24 |
| 19 | Fidelity® Extended Market Index | 635.50K (6.54%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 20 | JPM Thematics Genetic Thrps C2 Acc USD | 494.69K (5.09%) | -20.23K Decreased by -4.09% | Oct 31, 24 |