| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | BlackRock Inc | 15.44M (8.00%) | 263.65K Increased by +1.71% | Jun 30, 24 |
| 2 | Vanguard Group Inc | 10.30M (5.34%) | -197.16K Decreased by -1.91% | Jun 30, 24 |
| 3 | Granahan Investment Management Inc.. | 7.71M (3.99%) | -366.03K Decreased by -4.75% | Mar 31, 24 |
| 4 | Ameriprise Financial Inc | 6.39M (3.31%) | -561.00 Decreased by -0.01% | Jun 30, 24 |
| 5 | Pictet Asset Manangement SA | 5.69M (2.95%) | 539.78K Increased by +9.49% | Dec 31, 23 |
| 6 | Millennium Management LLC | 5.15M (2.67%) | -1.09M Decreased by -21.23% | Jun 30, 24 |
| 7 | Palo Alto Investors, LLC | 4.63M (2.40%) | 73.18K Increased by +1.58% | Jun 30, 24 |
| 8 | Geode Capital Management, LLC | 4.52M (2.34%) | 198.00K Increased by +4.38% | Jun 30, 24 |
| 9 | NORGES BANK | 4.00M (2.07%) | 3.96M Increased by +99.06% | Dec 31, 23 |
| 10 | State Street Corp | 3.80M (1.97%) | 370.41K Increased by +9.75% | Jun 30, 24 |
| 11 | State Street Corporation | 3.43M (1.78%) | -10.44M Decreased by -304.47% | Mar 31, 24 |
| 12 | Ghisallo Capital Management LLC | 3.15M (1.63%) | 3.15M Increased by +100.00% | Dec 31, 23 |
| 13 | Goldman Sachs Group Inc | 2.55M (1.32%) | 1.79M Increased by +70.20% | Dec 31, 23 |
| 14 | TANG CAPITAL MANAGEMENT LLC | 2.50M (1.29%) | -1.78M Decreased by -71.31% | Mar 31, 24 |
| 15 | Baker Bros Advisors LP | 2.50M (1.29%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 16 | FMR Inc | 2.30M (1.19%) | -85.55K Decreased by -3.73% | Jun 30, 24 |
| 17 | Renaissance Technologies Corp | 2.19M (1.13%) | -451.00K Decreased by -20.62% | Mar 31, 24 |
| 18 | Hudson Bay Capital Management LP | 2.18M (1.13%) | 1.53M Increased by +70.00% | Dec 31, 23 |
| 19 | Vestal Point Capital LP | 2.15M (1.11%) | 2.15M Increased by +100.00% | Dec 31, 23 |
| 20 | Partner Fund Management LP | 2.04M (1.06%) | -4.00M Decreased by -195.74% | Mar 31, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | SPDR® S&P Biotech ETF | 12.26M (6.35%) | 229.08K Increased by +1.87% | Feb 29, 24 |
| 2 | Vanguard Total Stock Mkt Idx Inv | 5.86M (3.04%) | 0.00 Increased by 0.00% | Jul 31, 24 |
| 3 | Columbia Acorn Inst | 5.37M (2.78%) | 0.00 Increased by 0.00% | Jul 31, 24 |
| 4 | iShares Russell 2000 ETF | 5.21M (2.70%) | 32.96K Increased by +0.63% | Aug 30, 24 |
| 5 | ACATIS Datini Valueflex Fonds A | 3.30M (1.71%) | 922.18K Increased by +27.94% | Jul 31, 24 |
| 6 | Vanguard Institutional Extnd Mkt Idx Tr | 3.19M (1.65%) | 0.00 Increased by 0.00% | Jul 31, 24 |
| 7 | Pictet Biopharmaceutical Mother | 2.63M (1.36%) | 1.06M Increased by +40.15% | Oct 13, 23 |
| 8 | Fidelity Select Pharmaceuticals Port | 2.23M (1.15%) | 0.00 Increased by 0.00% | Jul 31, 24 |
| 9 | Fidelity Small Cap Index | 1.89M (0.98%) | 0.00 Increased by 0.00% | Jun 30, 24 |
| 10 | iShares Russell 2000 Value ETF | 1.83M (0.95%) | -6.11K Decreased by -0.33% | Aug 30, 24 |
| 11 | M&G (ACS) Granahan US Sm Cp Gr GBPZ1AAcc | 1.81M (0.94%) | 86.07K Increased by +4.76% | Jan 31, 24 |
| 12 | JNL Multi-Manager Small Cap Growth A | 1.79M (0.93%) | -319.50K Decreased by -17.87% | Mar 31, 24 |
| 13 | CS (Lux) Digital Health Equity SB USD | 1.50M (0.78%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 14 | iShares Biotechnology ETF | 1.37M (0.71%) | 0.00 Increased by 0.00% | Aug 30, 24 |
| 15 | Granahan US SMID Select I GBP Acc | 1.21M (0.63%) | 7.68K Increased by +0.63% | Feb 29, 24 |
| 16 | State St Russell Sm/Mid Cp® Indx NL Cl C | 1.17M (0.61%) | 0.00 Increased by 0.00% | Jul 31, 24 |
| 17 | Direxion Daily S&P Biotech Bull 3X ETF | 1.12M (0.58%) | 0.00 Increased by 0.00% | Feb 29, 24 |
| 18 | Fidelity Extended Market Index | 1.12M (0.58%) | 25.62K Increased by +2.29% | Jul 31, 24 |
| 19 | Contrarius Global Equity Investor | 1.10M (0.57%) | -89.09K Decreased by -8.11% | Dec 31, 23 |
| 20 | Fidelity® Small Cap Index | 1.03M (0.53%) | 20.61K Increased by +2.01% | Oct 31, 23 |