| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Baker Bros Advisors LP | 10.89M (577.67%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 2 | FCPM III SERVICES BV | 3.45M (183.21%) | 0.00 Increased by 0.00% | Sep 30, 25 |
| 3 | Paradigm Biocapital Advisors LP | 3.25M (172.30%) | -460.24K Decreased by -14.18% | Mar 31, 24 |
| 4 | Armistice Capital, LLC | 3.24M (171.73%) | 258.00K Increased by +7.97% | Dec 31, 25 |
| 5 | Westfield Capital Management Company, L.P. | 3.02M (160.06%) | 63.48K Increased by +2.10% | Dec 31, 25 |
| 6 | Siren, L.L.C. | 2.01M (106.81%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 7 | Westfield Capital Management Company, LP | 1.85M (98.23%) | 327.09K Increased by +17.67% | Sep 30, 24 |
| 8 | Long Focus Capital Management, LLC | 1.63M (86.67%) | 214.40K Increased by +13.13% | Dec 31, 25 |
| 9 | T. Rowe Price Associates, Inc. | 1.38M (73.49%) | -83.60K Decreased by -6.04% | Sep 30, 25 |
| 10 | Acadian Asset Management LLC | 1.31M (69.76%) | 1.31M Increased by +100.00% | Sep 30, 25 |
| 11 | BRAIDWELL LP | 1.29M (68.45%) | 1.29M Increased by +100.00% | Sep 30, 23 |
| 12 | Deep Track Capital, LP | 1.20M (63.85%) | 436.23K Increased by +36.25% | Jun 30, 25 |
| 13 | Candriam Luxembourg S.C.A. | 1.17M (62.22%) | 0.00 Increased by 0.00% | Sep 30, 25 |
| 14 | Principal Financial Group Inc | 1.15M (60.94%) | 451.13K Increased by +39.28% | Sep 30, 25 |
| 15 | RA Capital Management, LLC | 1.09M (58.03%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 16 | Fairmount Funds Management LLC | 1.07M (56.74%) | 1.07M Increased by +100.00% | Jun 30, 24 |
| 17 | Millennium Management LLC | 1.05M (55.97%) | -388.87K Decreased by -36.87% | Sep 30, 25 |
| 18 | BNP Paribas Investment Partners SA | 1.04M (55.27%) | -178.23K Decreased by -17.11% | Jun 30, 25 |
| 19 | Polar Capital Holdings PLC | 1.00M (53.22%) | -1.75K Decreased by -0.18% | Sep 30, 24 |
| 20 | Tybourne Capital Management (HK) Ltd | 993.74K (52.74%) | 417.40K Increased by +42.00% | Jun 30, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Harbor Small Cap Growth Instl | 1.02M (54.25%) | 30.53K Increased by +2.99% | Dec 31, 25 |
| 2 | Westfield Capital Mgt Co Sm-Cap Gr Eq | 1.02M (54.25%) | 30.53K Increased by +2.99% | Dec 31, 25 |
| 3 | Candriam Eqs L Biotech C USD Cap | 825.13K (43.79%) | 19.89K Increased by +2.41% | Oct 31, 25 |
| 4 | T. Rowe Price Health Sciences | 794.47K (42.16%) | -60.33K Decreased by -7.59% | Jan 31, 26 |
| 5 | BNP Paribas Health Cr Innovtr Cl Cap | 568.51K (30.17%) | 568.51K Increased by +100.00% | Jan 31, 26 |
| 6 | Principal SmallCap R5 | 567.80K (30.13%) | 567.80K Increased by +100.00% | Jan 31, 26 |
| 7 | Principal U.S. Small Cap Equity | 567.80K (30.13%) | -500.00 Decreased by -0.09% | Dec 31, 25 |
| 8 | Principal U.S. Small Cap Select Equity | 567.80K (30.13%) | 542.00K Increased by +95.46% | Dec 31, 25 |
| 9 | Candriam Global Equities Oncology | 492.11K (26.12%) | 125.18K Increased by +25.44% | Sep 30, 24 |
| 10 | BNP Paribas US Small Cap ClassicC | 476.45K (25.28%) | 1.24K Increased by +0.26% | Jul 31, 25 |
| 11 | BNP Paribas US Small Cap Classic R | 468.06K (24.84%) | -9.43K Decreased by -2.01% | May 31, 25 |
| 12 | Janus Henderson Global Life Sciences | 385.75K (20.47%) | -89.69K Decreased by -23.25% | Sep 30, 23 |
| 13 | Janus Henderson Global Life Sciences D | 385.75K (20.47%) | -89.69K Decreased by -23.25% | Sep 30, 23 |
| 14 | Belfius Equities Cure C Cap | 367.15K (19.48%) | 0.00 Increased by 0.00% | Nov 30, 25 |
| 15 | MEDICAL BioHealth EUR Acc | 343.42K (18.22%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 16 | Janus Selection Global Life Science AUSD | 298.27K (15.83%) | -76.67K Decreased by -25.71% | Sep 30, 23 |
| 17 | Polar Capital Biotech S Inc | 297.67K (15.80%) | -592.95K Decreased by -199.20% | Nov 30, 24 |
| 18 | AXA Framlington Health R Inc | 279.70K (14.84%) | -8.49K Decreased by -3.03% | Nov 30, 23 |
| 19 | Platinum International Healthcare | 272.15K (14.44%) | -21.30K Decreased by -7.83% | Oct 31, 24 |
| 20 | UTM IM GBP AXA Framlington Biotech | 268.72K (14.26%) | 0.00 Increased by 0.00% | Jul 31, 25 |