| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | BlackRock Inc | 22.65M (10.25%) | -748.13K Decreased by -3.30% | Mar 31, 26 |
| 2 | Vanguard Group Inc | 22.27M (10.08%) | 482.49K Increased by +2.17% | Dec 31, 25 |
| 3 | State Street Corporation | 17.48M (7.91%) | 4.70M Increased by +26.89% | Mar 31, 24 |
| 4 | RA Capital Management, LLC | 15.83M (7.16%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 5 | Deerfield Management Co | 15.04M (6.80%) | 697.00K Increased by +4.63% | Mar 31, 26 |
| 6 | State Street Corp | 12.21M (5.52%) | 604.70K Increased by +4.95% | Mar 31, 26 |
| 7 | Vanguard Portfolio Management, LLC | 11.24M (5.09%) | 11.24M Increased by +100.00% | Mar 31, 26 |
| 8 | Vanguard Capital Management, LLC | 11.14M (5.04%) | 11.14M Increased by +100.00% | Mar 31, 26 |
| 9 | TCG Crossover Management, LLC | 11.02M (4.99%) | 11.02M Increased by +100.00% | Mar 31, 26 |
| 10 | HHG PLC | 8.91M (4.03%) | 1.50M Increased by +16.88% | Mar 31, 26 |
| 11 | Perceptive Advisors LLC | 7.43M (3.36%) | 445.11K Increased by +5.99% | Mar 31, 26 |
| 12 | Vestal Point Capital LP | 7.03M (3.18%) | 4.78M Increased by +67.97% | Mar 31, 26 |
| 13 | Two Sigma Investments LLC | 6.39M (2.89%) | 1.88M Increased by +29.37% | Mar 31, 26 |
| 14 | Geode Capital Management, LLC | 5.78M (2.62%) | 95.47K Increased by +1.65% | Mar 31, 26 |
| 15 | Alkeon Capital Management, LLC | 5.71M (2.59%) | -1.50M Decreased by -26.25% | Jun 30, 25 |
| 16 | Kynam Capital Management, LP | 5.68M (2.57%) | -3.69M Decreased by -64.88% | Mar 31, 26 |
| 17 | Morgan Stanley - Brokerage Accounts | 5.20M (2.35%) | -126.72K Decreased by -2.44% | Sep 30, 25 |
| 18 | Bank of America Corp | 5.09M (2.30%) | 3.51M Increased by +68.88% | Mar 31, 26 |
| 19 | Aberdeen Group PLC | 5.04M (2.28%) | 4.13M Increased by +81.88% | Mar 31, 26 |
| 20 | UBS Group AG | 4.94M (2.24%) | -1.74M Decreased by -35.10% | Mar 31, 26 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | BioPharma Credit Ord | 17.22M (7.79%) | 17.22M Increased by +100.00% | Dec 31, 24 |
| 2 | Vanguard Total Stock Mkt Idx Inv | 8.04M (3.64%) | 24.91K Increased by +0.31% | Apr 30, 26 |
| 3 | State Street® SPDR® S&P® Biotech ETF | 7.37M (3.33%) | -45.33K Decreased by -0.62% | May 31, 26 |
| 4 | Vanguard US Total Market Shares ETF | 6.57M (2.97%) | -18.55K Decreased by -0.28% | Sep 30, 24 |
| 5 | iShares Russell 2000 ETF | 5.41M (2.45%) | 50.02K Increased by +0.92% | May 29, 26 |
| 6 | SPDR® S&P Biotech ETF | 3.67M (1.66%) | 8.19K Increased by +0.22% | Aug 31, 25 |
| 7 | Vanguard Small Cap Index | 2.88M (1.30%) | -11.49K Decreased by -0.40% | Apr 30, 26 |
| 8 | Pictet-Biotech P USD | 2.79M (1.26%) | -13.26K Decreased by -0.47% | Jul 31, 23 |
| 9 | Vanguard Institutional Extnd Mkt Idx Tr | 2.72M (1.23%) | 30.09K Increased by +1.11% | Apr 30, 26 |
| 10 | ACAP Strategic A | 2.70M (1.22%) | -121.24K Decreased by -4.49% | Sep 30, 25 |
| 11 | Fidelity® Select Biotechnology | 2.58M (1.17%) | -225.50K Decreased by -8.74% | Nov 30, 23 |
| 12 | Vanguard Strategic Equity Inv | 2.26M (1.02%) | -315.88K Decreased by -14.01% | Mar 31, 26 |
| 13 | Fidelity Small Cap Index | 2.22M (1.00%) | -64.26K Decreased by -2.90% | Mar 31, 26 |
| 14 | abrdn Healthcare Investors | 2.18M (0.99%) | 0.00 Increased by 0.00% | May 31, 26 |
| 15 | abrdn Healthcare Opportunities | 2.09M (0.94%) | 127.84K Increased by +6.12% | Apr 30, 26 |
| 16 | Hood River Small-Cap Growth Instl | 1.99M (0.90%) | 1.32M Increased by +66.20% | Sep 30, 25 |
| 17 | Eventide Healthcare & Life Sciences I | 1.97M (0.89%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 18 | Fidelity® Small Cap Index | 1.82M (0.83%) | 49.54K Increased by +2.71% | Oct 31, 23 |
| 19 | Janus Henderson Hrzn Biotec E2 USD | 1.82M (0.82%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 20 | Pictet-Global Megatrend Sel I USD | 1.75M (0.79%) | 438.00 Increased by +0.02% | Jul 31, 23 |