| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | RA Capital Management, LLC | 9.19M (2.69 K%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 2 | Sofinnova Ventures | 3.76M (1.10 K%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 3 | TCG Crossover Management, LLC | 2.24M (655.51%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 4 | BRAIDWELL LP | 1.44M (421.39%) | 1.44M Increased by +100.00% | Dec 31, 24 |
| 5 | Deerfield Management Co | 1.41M (412.94%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 6 | Logos Global Management LP | 1.40M (409.55%) | 1.40M Increased by +100.00% | Dec 31, 24 |
| 7 | Cormorant Asset Management, LLC | 1.07M (312.95%) | -141.90K Decreased by -13.26% | Mar 31, 24 |
| 8 | Vanguard Group Inc | 1.00M (293.09%) | -149.97K Decreased by -14.97% | Dec 31, 24 |
| 9 | BlackRock Inc | 975.42K (285.34%) | 21.75K Increased by +2.23% | Dec 31, 24 |
| 10 | ADAR1 Capital Management LLC | 928.02K (271.48%) | 814.94K Increased by +87.82% | Dec 31, 24 |
| 11 | Great Point Partners LLC | 887.69K (259.68%) | -150.00K Decreased by -16.90% | Mar 31, 24 |
| 12 | Allostery Investments LP | 850.68K (248.85%) | 850.68K Increased by +100.00% | Dec 31, 24 |
| 13 | Artal Group S A | 809.60K (236.84%) | 809.60K Increased by +100.00% | Jun 30, 24 |
| 14 | Affinity Asset Advisors, LLC | 800.00K (234.03%) | 200.00K Increased by +25.00% | Dec 31, 24 |
| 15 | Driehaus Capital Management LLC | 794.99K (232.56%) | -263.22K Decreased by -33.11% | Mar 31, 24 |
| 16 | Morgan Stanley - Brokerage Accounts | 786.54K (230.09%) | 452.57K Increased by +57.54% | Dec 31, 24 |
| 17 | Baker Bros Advisors LP | 628.94K (183.99%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 18 | OUP Management Co., LLC | 603.76K (176.62%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 19 | Jefferies Financial Group Inc | 600.00K (175.52%) | 600.00K Increased by +100.00% | Dec 31, 24 |
| 20 | Orbimed Advisors, LLC | 565.37K (165.39%) | -191.56K Decreased by -33.88% | Mar 31, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 536.62K (156.98%) | 52.67K Increased by +9.82% | Mar 31, 25 |
| 2 | iShares Russell 2000 ETF | 458.98K (134.27%) | -3.96K Decreased by -0.86% | Mar 31, 25 |
| 3 | Eventide Healthcare & Life Sciences I | 445.50K (130.32%) | 433.32K Increased by +97.27% | Mar 31, 24 |
| 4 | Fidelity Select Biotechnology | 311.68K (91.18%) | 0.00 Increased by 0.00% | Mar 31, 24 |
| 5 | Fidelity® Select Biotechnology | 311.68K (91.18%) | 94.33K Increased by +30.26% | Nov 30, 23 |
| 6 | Fidelity Advisor® Biotechnology I | 238.36K (69.73%) | -10.34K Decreased by -4.34% | Nov 30, 23 |
| 7 | Fidelity Advisor Biotechnology I | 224.00K (65.53%) | 0.00 Increased by 0.00% | Mar 31, 24 |
| 8 | Vanguard VIF Small Co Gr | 213.89K (62.57%) | -76.53K Decreased by -35.78% | Dec 31, 24 |
| 9 | Vanguard Institutional Extnd Mkt Idx Tr | 202.52K (59.24%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 10 | State St Russell Sm/Mid Cp® Indx NL Cl C | 172.19K (50.37%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 11 | State St Russell Sm/Mid Cp® Indx SL Cl I | 172.19K (50.37%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 12 | Fidelity Small Cap Index | 144.55K (42.29%) | -2.71K Decreased by -1.87% | Jan 31, 25 |
| 13 | Bridge Builder Tax Managed Sm/Md Cp | 124.13K (36.31%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 14 | iShares Russell 2000 Growth ETF | 110.99K (32.47%) | -528.00 Decreased by -0.48% | Mar 31, 25 |
| 15 | Fidelity® Small Cap Index | 108.00K (31.59%) | 1.59K Increased by +1.47% | Oct 31, 23 |
| 16 | Fidelity® Extended Market Index | 70.20K (20.53%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 17 | Heptagon Driehaus US Micro Cap Eq C$ Acc | 69.13K (20.22%) | 1.67K Increased by +2.42% | Mar 31, 24 |
| 18 | Fidelity Extended Market Index | 68.22K (19.96%) | -435.00 Decreased by -0.64% | Feb 28, 25 |
| 19 | Voya Index Plus SmallCap Port I | 65.66K (19.21%) | 0.00 Increased by 0.00% | Oct 31, 24 |
| 20 | Biotech Growth Ord | 64.83K (18.96%) | -285.45K Decreased by -440.34% | May 31, 24 |