| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | HHG PLC | 10.64M (11.75%) | 3.12M Increased by +29.29% | Sep 30, 23 |
| 2 | RTW INVESTMENTS, LLC | 7.14M (7.88%) | 325.77K Increased by +4.56% | Sep 30, 23 |
| 3 | Gendell Jeffrey L | 5.62M (6.2%) | 219.29K Increased by +3.91% | Sep 30, 23 |
| 4 | Polar Capital Holdings PLC | 4.51M (4.98%) | -21.96K Decreased by -0.49% | Sep 30, 23 |
| 5 | Vivo Capital, LLC | 4.1M (4.52%) | 266.85K Increased by +6.51% | Sep 30, 23 |
| 6 | WEALTH EFFECTS LLC | 2.41M (2.66%) | 40.2K Increased by +1.67% | Sep 30, 23 |
| 7 | COWEN AND COMPANY, LLC | 2.34M (2.58%) | -325.77K Decreased by -13.93% | Sep 30, 23 |
| 8 | Woodline Partners LP | 1.9M (2.1%) | 23.5K Increased by +1.23% | Sep 30, 23 |
| 9 | Adage Capital Partners Gp LLC | 1.73M (1.9%) | -955K Decreased by -55.36% | Sep 30, 23 |
| 10 | Brandes Investment Partners & Co | 1.45M (1.6%) | 159.58K Increased by +11.01% | Sep 30, 23 |
| 11 | TANG CAPITAL MANAGEMENT LLC | 1M (1.1%) | 1M Increased by +100% | Sep 30, 23 |
| 12 | Tri Locum Partners LP | 983.6K (1.09%) | -55.87K Decreased by -5.68% | Sep 30, 23 |
| 13 | Samsara BioCapital, LLC | 967.53K (1.07%) | 0 Increased by 0% | Sep 30, 23 |
| 14 | Renaissance Technologies Corp | 738.91K (0.82%) | 46.8K Increased by +6.33% | Sep 30, 23 |
| 15 | Kennedy Capital Management Inc | 715.42K (0.79%) | 268.7K Increased by +37.56% | Sep 30, 23 |
| 16 | MPM Oncology Impact Management LP | 664.22K (0.73%) | 279.23K Increased by +42.04% | Sep 30, 23 |
| 17 | Knoll Capital Management LP | 600K (0.66%) | 100K Increased by +16.67% | Sep 30, 23 |
| 18 | Modera Wealth Management, LLC | 594K (0.66%) | 0 Increased by 0% | Sep 30, 23 |
| 19 | D. E. Shaw & Co LP | 549.37K (0.61%) | -216.47K Decreased by -39.4% | Sep 30, 23 |
| 20 | Citadel Advisors Llc | 463.11K (0.51%) | -23.09K Decreased by -4.99% | Sep 30, 23 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Polar Capital Healthcare Opports Inc | 4M (4.42%) | 0 Increased by 0% | Jan 31, 24 |
| 2 | Janus Henderson Global Life Sciences | 2.9M (3.2%) | -18.02K Decreased by -0.62% | Dec 31, 23 |
| 3 | Janus Henderson Global Life Sciences D | 2.9M (3.2%) | -18.02K Decreased by -0.62% | Dec 31, 23 |
| 4 | Janus Henderson Glb Life Scn I2 USD | 2.19M (2.42%) | 1.63K Increased by +0.07% | Jan 31, 24 |
| 5 | Janus Selection Global Life Science AUSD | 2.19M (2.42%) | -68.46K Decreased by -3.12% | Dec 31, 23 |
| 6 | Polar Capital Biotech S Inc | 1.75M (1.93%) | 0 Increased by 0% | Jan 31, 24 |
| 7 | Janus Henderson US Small Cap Growth | 1.18M (1.3%) | 83.85K Increased by +7.1% | Dec 31, 23 |
| 8 | Janus Henderson Venture D | 1.18M (1.3%) | 83.85K Increased by +7.1% | Dec 31, 23 |
| 9 | SEB Läkemedelsfond | 544.6K (0.6%) | 0 Increased by 0% | Jan 31, 24 |
| 10 | Janus Henderson Hrzn Biotec E2 USD | 502.84K (0.56%) | 45.66K Increased by +9.08% | Jan 31, 24 |
| 11 | DWS Small Cap Core S | 500K (0.55%) | 200K Increased by +40% | Jan 31, 24 |
| 12 | PSI Polar Capital Fut Hlthcr I USD Acc | 365K (0.4%) | 0 Increased by 0% | Sep 30, 23 |
| 13 | Kennedy Extended Small Cap | 305.06K (0.34%) | -45.48K Decreased by -14.91% | Dec 31, 23 |
| 14 | MM Access II Fut of Earth USD F Acc | 263.3K (0.29%) | 0 Increased by 0% | Feb 29, 24 |
| 15 | Brandes International Small Cap Equity A | 250.77K (0.28%) | 0 Increased by 0% | Dec 31, 23 |
| 16 | Brandes International Small Cap Eq | 199.12K (0.22%) | 0 Increased by 0% | Jan 31, 24 |
| 17 | Arctic Aurora LifeScience I USD | 187.78K (0.21%) | 0 Increased by 0% | Jan 31, 24 |
| 18 | APO Medical Opportunities R | 174K (0.19%) | 174K Increased by +100% | Jan 31, 24 |
| 19 | Kennedy Small Cap Growth | 164.97K (0.18%) | -2.45K Decreased by -1.49% | Dec 31, 23 |
| 20 | Kennedy Small Cap Select | 150.67K (0.17%) | -16.39K Decreased by -10.88% | Dec 31, 23 |