| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | HHG PLC | 11.13M (13.80%) | -2.46M Decreased by -22.10% | Jun 30, 25 |
| 2 | RTW INVESTMENTS, LLC | 6.95M (8.61%) | -188.50K Decreased by -2.71% | Dec 31, 23 |
| 3 | BlackRock Inc | 6.80M (8.43%) | 1.35M Increased by +19.84% | Jun 30, 25 |
| 4 | Brandes Investment Partners & Co | 6.49M (8.04%) | 820.47K Increased by +12.65% | Jun 30, 25 |
| 5 | Two Seas Capital LP | 6.16M (7.63%) | 1.21M Increased by +19.64% | Jun 30, 25 |
| 6 | Vanguard Group Inc | 5.56M (6.90%) | 1.66M Increased by +29.83% | Jun 30, 25 |
| 7 | Gendell Jeffrey L | 5.18M (6.42%) | -950.54K Decreased by -18.36% | Jun 30, 25 |
| 8 | BRAIDWELL LP | 4.11M (5.09%) | 716.79K Increased by +17.46% | Dec 31, 24 |
| 9 | Polar Capital Holdings PLC | 4.00M (4.96%) | -356.63K Decreased by -8.92% | Jun 30, 25 |
| 10 | Vivo Capital, LLC | 2.68M (3.33%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 11 | WEALTH EFFECTS LLC | 2.35M (2.92%) | -14.30K Decreased by -0.61% | Jun 30, 25 |
| 12 | Geode Capital Management, LLC | 2.17M (2.69%) | 979.42K Increased by +45.16% | Jun 30, 25 |
| 13 | Goldman Sachs Group Inc | 2.15M (2.66%) | 286.22K Increased by +13.34% | Dec 31, 24 |
| 14 | TANG CAPITAL MANAGEMENT LLC | 2.10M (2.60%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 15 | State Street Corp | 2.07M (2.57%) | 412.10K Increased by +19.89% | Jun 30, 25 |
| 16 | COWEN AND COMPANY, LLC | 1.64M (2.04%) | -695.96K Decreased by -42.38% | Dec 31, 23 |
| 17 | Citadel Advisors Llc | 1.53M (1.89%) | -716.69K Decreased by -46.89% | Jun 30, 25 |
| 18 | Millennium Management LLC | 1.21M (1.50%) | 233.99K Increased by +19.31% | Dec 31, 24 |
| 19 | Morgan Stanley - Brokerage Accounts | 1.19M (1.48%) | 157.99K Increased by +13.25% | Jun 30, 25 |
| 20 | Bank of America Corp | 1.12M (1.39%) | 1.04M Increased by +92.57% | Mar 31, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Polar Capital Healthcare Opports Inc | 3.69M (4.57%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 2 | Vanguard US Total Market Shares ETF | 2.99M (3.70%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 3 | Vanguard Total Stock Mkt Idx Inv | 2.87M (3.56%) | -63.75K Decreased by -2.22% | Jul 31, 25 |
| 4 | Janus Henderson Global Life Sciences | 2.27M (2.82%) | -207.97K Decreased by -9.15% | Jun 30, 25 |
| 5 | Janus Henderson Global Life Sciences D | 2.27M (2.82%) | -178.86K Decreased by -7.87% | Jun 30, 25 |
| 6 | iShares Russell 2000 ETF | 2.15M (2.66%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 7 | Janus Selection Global Life Science AUSD | 2.12M (2.62%) | -94.87K Decreased by -4.48% | Jun 30, 24 |
| 8 | Janus Global Life Science AUSD | 1.89M (2.34%) | -131.51K Decreased by -6.97% | Jun 30, 25 |
| 9 | Janus Henderson Glb Life Scn I2 USD | 1.72M (2.13%) | -159.56K Decreased by -9.27% | Jul 31, 25 |
| 10 | Polar Capital Biotech S Inc | 1.50M (1.86%) | 0.00 Increased by 0.00% | Aug 31, 24 |
| 11 | Janus Henderson US Small Cap Growth | 1.48M (1.83%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 12 | Janus Henderson Venture D | 1.48M (1.83%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 13 | Janus Henderson US Small Cap Growth MA | 1.48M (1.83%) | 1.48M Increased by +99.99% | Dec 31, 24 |
| 14 | Brandes International Small Cap Equity A | 1.40M (1.74%) | 232.59K Increased by +16.57% | Jun 30, 25 |
| 15 | Brandes European Value I USD | 1.06M (1.31%) | 4.00 Increased by +0.00% | Jul 31, 25 |
| 16 | Vanguard Institutional Extnd Mkt Idx Tr | 1.05M (1.30%) | -459.68K Decreased by -43.81% | Jul 31, 25 |
| 17 | Fidelity Small Cap Index | 898.93K (1.11%) | -40.35K Decreased by -4.49% | Jun 30, 25 |
| 18 | MEDICAL BioHealth EUR Acc | 848.94K (1.05%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 19 | iShares Russell 2000 Growth ETF | 787.96K (0.98%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 20 | Janus Henderson Hrzn Biotec E2 USD | 714.72K (0.89%) | -336.68K Decreased by -47.11% | Jun 30, 25 |