| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Wellington Management Company LLP | 27.15M (32.19%) | 55.34K Increased by +0.20% | Jun 30, 25 |
| 2 | Mak Capital One LLC | 26.02M (30.85%) | 9.06M Increased by +34.83% | Sep 30, 25 |
| 3 | Blackstone Inc | 20.49M (24.29%) | 0.00 Increased by 0.00% | Sep 30, 25 |
| 4 | Armistice Capital, LLC | 17.50M (20.75%) | 1.90M Increased by +10.86% | Dec 31, 25 |
| 5 | Syncona Portfolio Ltd. | 16.64M (19.73%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 6 | venBio Select Advisor LLC | 9.91M (11.75%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 7 | Polygon Management Ltd | 9.50M (11.26%) | 0.00 Increased by 0.00% | Sep 30, 25 |
| 8 | Schroder Investment Management Group | 9.49M (11.25%) | 1.06M Increased by +11.13% | Dec 31, 25 |
| 9 | FMR Inc | 7.11M (8.43%) | -3.06M Decreased by -43.02% | Jun 30, 25 |
| 10 | Cormorant Asset Management, LLC | 6.62M (7.85%) | 1.17M Increased by +17.63% | Mar 31, 24 |
| 11 | Paradigm Biocapital Advisors LP | 6.43M (7.62%) | -6.19M Decreased by -96.26% | Mar 31, 24 |
| 12 | Citadel Advisors Llc | 6.04M (7.17%) | 5.04M Increased by +83.38% | Sep 30, 25 |
| 13 | Frazier Life Sciences Management, L.P. | 4.62M (5.48%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 14 | Perceptive Advisors LLC | 4.33M (5.14%) | 2.50M Increased by +57.72% | Mar 31, 24 |
| 15 | Deerfield Management Co | 3.64M (4.31%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 16 | BlackRock Inc | 3.47M (4.12%) | -16.36K Decreased by -0.47% | Sep 30, 25 |
| 17 | BNP Paribas Asset Management (Former AXA IM) | 3.36M (3.99%) | 3.36M Increased by +100.00% | Sep 30, 25 |
| 18 | LAURION CAPITAL MANAGEMENT LP | 3.32M (3.93%) | 0.00 Increased by 0.00% | Sep 30, 25 |
| 19 | Candriam Luxembourg S.C.A. | 3.19M (3.78%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 20 | AXA SA | 3.13M (3.71%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Syncona Ord | 30.73M (36.44%) | 9.39M Increased by +30.55% | Sep 30, 24 |
| 2 | Vanguard Health Care Inv | 19.36M (22.95%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 3 | International Biotechnology Ord | 6.76M (8.02%) | 3.09M Increased by +45.69% | Sep 30, 25 |
| 4 | FIAM Small Cap Core CIT Cl B | 4.02M (4.76%) | 946.70K Increased by +23.57% | Jun 30, 25 |
| 5 | AXA Framlington Health Fund - R Income | 3.36M (3.99%) | 0.00 Increased by 0.00% | Jan 31, 26 |
| 6 | FIAM Small Cap Core Composite | 3.14M (3.72%) | -26.57K Decreased by -0.85% | Mar 31, 25 |
| 7 | Fidelity Small Cap Growth | 2.57M (3.05%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 8 | US Small-Cap Growth II Equity Comp | 2.02M (2.39%) | -216.32K Decreased by -10.71% | Jun 30, 25 |
| 9 | Wellington Global Hlthcr Eq USD G Ac | 1.79M (2.12%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 10 | Fidelity Stock Selector Small Cap | 1.62M (1.92%) | -348.11K Decreased by -21.54% | Jan 31, 25 |
| 11 | Fidelity Series Small Cap Opps | 1.41M (1.67%) | -348.96K Decreased by -24.79% | Jan 31, 25 |
| 12 | iShares Biotechnology ETF | 1.38M (1.64%) | 0.00 Increased by 0.00% | Feb 28, 26 |
| 13 | T. Rowe Price New Horizons | 1.37M (1.62%) | -650.87K Decreased by -47.56% | Jul 31, 25 |
| 14 | Fidelity Series Small Cap Core | 1.30M (1.55%) | 354.70K Increased by +27.18% | Jun 30, 25 |
| 15 | Belfius Equities Cure C Cap | 1.26M (1.50%) | -413.50K Decreased by -32.69% | Apr 30, 25 |
| 16 | Fidelity Select Biotechnology | 1.24M (1.47%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 17 | Candriam Eqs L Biotech C USD Cap | 1.17M (1.39%) | -340.33K Decreased by -29.02% | Apr 30, 25 |
| 18 | Strategic Advisers Fidelity US TtlStk | 1.15M (1.37%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 19 | Vanguard International Explorer Inv | 1.10M (1.31%) | -36.35K Decreased by -3.30% | Jun 30, 25 |
| 20 | Fidelity Small Cap Growth K6 | 1.09M (1.29%) | 0.00 Increased by 0.00% | Mar 31, 25 |