| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Matrix Capital Management Company, LLC | 6.92M (19.63%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 2 | Adage Capital Partners Gp LLC | 4.88M (13.84%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 3 | Long Focus Capital Management, LLC | 4.62M (13.10%) | 1.30M Increased by +28.14% | Jun 30, 25 |
| 4 | Suvretta Capital Management, LLC | 4.37M (12.40%) | 1.64M Increased by +37.53% | Jun 30, 25 |
| 5 | Eventide Asset Management, LLC | 4.08M (11.57%) | -1.72M Decreased by -42.20% | Dec 31, 24 |
| 6 | BlackRock Inc | 3.54M (10.04%) | -11.51K Decreased by -0.33% | Mar 31, 25 |
| 7 | Medicxi Ventures Management (Jersey) Ltd | 3.04M (8.62%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 8 | Vanguard Group Inc | 2.48M (7.03%) | 525.17K Increased by +21.20% | Jun 30, 25 |
| 9 | Franklin Resources Inc | 2.34M (6.64%) | 130.22K Increased by +5.56% | Jun 30, 25 |
| 10 | Nantahala Capital Management, LLC | 2.12M (6.01%) | 850.00K Increased by +40.14% | Jun 30, 25 |
| 11 | Easterly Investment Partners. | 1.50M (4.24%) | 134.79K Increased by +9.01% | Jun 30, 25 |
| 12 | Goldman Sachs Group Inc | 1.03M (2.92%) | 33.28K Increased by +3.23% | Jun 30, 24 |
| 13 | Geode Capital Management, LLC | 1.03M (2.91%) | 12.76K Increased by +1.24% | Mar 31, 25 |
| 14 | Samsara BioCapital, LLC | 1.00M (2.84%) | 1.00M Increased by +100.00% | Jun 30, 25 |
| 15 | State Street Corp | 793.01K (2.25%) | -8.81K Decreased by -1.11% | Mar 31, 25 |
| 16 | UBS Group AG | 753.16K (2.14%) | 65.84K Increased by +8.74% | Mar 31, 25 |
| 17 | Rock Springs Capital Management LP | 722.90K (2.05%) | -296.86K Decreased by -41.07% | Sep 30, 23 |
| 18 | Regency Capital Management Inc.\DE | 665.88K (1.89%) | -83.60K Decreased by -12.55% | Jun 30, 25 |
| 19 | B Group, Inc | 572.58K (1.62%) | 100.00K Increased by +17.46% | Jun 30, 25 |
| 20 | State Street Corporation | 569.80K (1.62%) | 63.54K Increased by +11.15% | Mar 31, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Eventide Healthcare & Life Sciences I | 4.08M (11.57%) | -1.72M Decreased by -42.20% | Dec 31, 24 |
| 2 | Franklin Biotechnology Discv A(acc)USD | 1.49M (4.22%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 3 | Vanguard Total Stock Mkt Idx Inv | 1.37M (3.87%) | -30.36K Decreased by -2.22% | Jul 31, 25 |
| 4 | iShares Russell 2000 ETF | 970.88K (2.75%) | -10.84K Decreased by -1.12% | Aug 29, 25 |
| 5 | Franklin Biotechnology Discovery A | 820.94K (2.33%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 6 | Vanguard Institutional Extnd Mkt Idx Tr | 427.12K (1.21%) | -194.62K Decreased by -45.57% | Jul 31, 25 |
| 7 | Fidelity Small Cap Index | 377.17K (1.07%) | -93.22K Decreased by -24.71% | Jun 30, 25 |
| 8 | Fidelity® Select Biotechnology | 356.49K (1.01%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 9 | T. Rowe Price Health Sciences | 327.62K (0.93%) | -12.34K Decreased by -3.77% | Jun 30, 25 |
| 10 | iShares Biotechnology ETF | 276.23K (0.78%) | -2.43K Decreased by -0.88% | Aug 29, 25 |
| 11 | Fidelity® Small Cap Index | 256.25K (0.73%) | 5.60K Increased by +2.19% | Oct 31, 23 |
| 12 | State St Russell Sm/Mid Cp® Indx SL Cl I | 256.14K (0.73%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 13 | iShares Russell 2000 Value ETF | 220.14K (0.62%) | -486.00 Decreased by -0.22% | Aug 29, 25 |
| 14 | Fidelity Extended Market Index | 208.89K (0.59%) | -1.72K Decreased by -0.82% | Jul 31, 25 |
| 15 | State St Russell Sm/Mid Cp® Indx NL Cl C | 187.04K (0.53%) | 1.07K Increased by +0.57% | Apr 30, 25 |
| 16 | Vanguard Russell 2000 ETF | 176.89K (0.50%) | -13.92K Decreased by -7.87% | Jul 31, 25 |
| 17 | State St Russell Sm Cap® Indx SL Cl I | 169.80K (0.48%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 18 | Fidelity Select Biotechnology | 133.59K (0.38%) | -96.00K Decreased by -71.86% | Sep 30, 24 |
| 19 | Fidelity® Extended Market Index | 130.62K (0.37%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 20 | Vanguard Health Care ETF | 116.29K (0.33%) | -1.31K Decreased by -1.13% | Jul 31, 25 |