| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Matrix Capital Management Company, LLC | 6.92M (20.92%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 2 | Adage Capital Partners Gp LLC | 4.88M (14.75%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 3 | Eventide Asset Management, LLC | 4.08M (12.33%) | -1.72M Decreased by -42.20% | Dec 31, 24 |
| 4 | BlackRock Inc | 3.54M (10.70%) | -11.51K Decreased by -0.33% | Mar 31, 25 |
| 5 | Long Focus Capital Management, LLC | 3.32M (10.03%) | 781.81K Increased by +23.55% | Mar 31, 25 |
| 6 | Medicxi Ventures Management (Jersey) Ltd | 3.04M (9.19%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 7 | Suvretta Capital Management, LLC | 2.73M (8.25%) | 2.73M Increased by +100.00% | Mar 31, 25 |
| 8 | Franklin Resources Inc | 2.21M (6.68%) | 487.53K Increased by +22.05% | Mar 31, 25 |
| 9 | Vanguard Group Inc | 1.95M (5.90%) | 34.60K Increased by +1.77% | Mar 31, 25 |
| 10 | Easterly Investment Partners. | 1.36M (4.11%) | 1.36M Increased by +100.00% | Mar 31, 25 |
| 11 | Nantahala Capital Management, LLC | 1.27M (3.83%) | -2.34K Decreased by -0.18% | Mar 31, 25 |
| 12 | Goldman Sachs Group Inc | 1.03M (3.11%) | 33.28K Increased by +3.23% | Jun 30, 24 |
| 13 | Geode Capital Management, LLC | 1.03M (3.10%) | 12.76K Increased by +1.24% | Mar 31, 25 |
| 14 | State Street Corp | 793.01K (2.40%) | -8.81K Decreased by -1.11% | Mar 31, 25 |
| 15 | Regency Capital Management Inc.\DE | 749.48K (2.26%) | 140.06K Increased by +18.69% | Mar 31, 25 |
| 16 | Rock Springs Capital Management LP | 722.90K (2.18%) | -296.86K Decreased by -41.07% | Sep 30, 23 |
| 17 | UBS Group AG | 687.32K (2.08%) | 665.34K Increased by +96.80% | Dec 31, 24 |
| 18 | State Street Corporation | 569.80K (1.72%) | 63.54K Increased by +11.15% | Mar 31, 24 |
| 19 | T. Rowe Price Associates, Inc. | 519.78K (1.57%) | -37.16K Decreased by -7.15% | Mar 31, 25 |
| 20 | Decheng Capital LLC | 515.55K (1.56%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Eventide Healthcare & Life Sciences I | 4.08M (12.33%) | -1.72M Decreased by -42.20% | Dec 31, 24 |
| 2 | Franklin Biotechnology Discv A(acc)USD | 1.49M (4.50%) | 84.00K Increased by +5.64% | May 31, 25 |
| 3 | Vanguard Total Stock Mkt Idx Inv | 1.40M (4.22%) | 376.40K Increased by +26.95% | May 31, 25 |
| 4 | iShares Russell 2000 ETF | 1.15M (3.48%) | 0.00 Increased by 0.00% | May 31, 25 |
| 5 | Franklin Biotechnology Discovery A | 820.94K (2.48%) | 40.72K Increased by +4.96% | May 31, 25 |
| 6 | Vanguard Institutional Extnd Mkt Idx Tr | 619.59K (1.87%) | 9.72K Increased by +1.57% | May 31, 25 |
| 7 | Fidelity Small Cap Index | 457.87K (1.38%) | -3.66K Decreased by -0.80% | Mar 31, 25 |
| 8 | iShares Russell 2000 Value ETF | 425.54K (1.29%) | 0.00 Increased by 0.00% | May 31, 25 |
| 9 | Fidelity® Select Biotechnology | 356.49K (1.08%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 10 | T. Rowe Price Health Sciences | 349.61K (1.06%) | -5.28K Decreased by -1.51% | Mar 31, 25 |
| 11 | iShares Biotechnology ETF | 268.21K (0.81%) | 0.00 Increased by 0.00% | May 31, 25 |
| 12 | Fidelity® Small Cap Index | 256.25K (0.77%) | 5.60K Increased by +2.19% | Oct 31, 23 |
| 13 | State St Russell Sm/Mid Cp® Indx SL Cl I | 256.14K (0.77%) | 69.10K Increased by +26.98% | May 31, 25 |
| 14 | Vanguard Russell 2000 ETF | 231.91K (0.70%) | 2.07K Increased by +0.89% | May 31, 25 |
| 15 | Fidelity Extended Market Index | 212.10K (0.64%) | -2.03K Decreased by -0.96% | Apr 30, 25 |
| 16 | State St Russell Sm/Mid Cp® Indx NL Cl C | 187.04K (0.57%) | 1.07K Increased by +0.57% | Apr 30, 25 |
| 17 | State St Russell Sm Cap® Indx SL Cl I | 169.80K (0.51%) | 0.00 Increased by 0.00% | May 31, 25 |
| 18 | Fidelity Select Biotechnology | 133.59K (0.40%) | -96.00K Decreased by -71.86% | Sep 30, 24 |
| 19 | Fidelity® Extended Market Index | 130.62K (0.39%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 20 | Schwab Small Cap Index | 117.96K (0.36%) | 4.86K Increased by +4.12% | May 31, 25 |