| Rank | Holder | SharesFloat % | Change | Date reported | 
|---|---|---|---|---|
| 1 | UBS Group AG | 7.70M (4.81%) | 2.16M  Increased by +28.11% | Jun 30, 25 | 
| 2 | Adage Capital Partners Gp LLC | 5.43M (3.39%) | 5.43M  Increased by +100.00% | Jun 30, 25 | 
| 3 | Morgan Stanley - Brokerage Accounts | 3.49M (2.18%) | 200.76K  Increased by +5.75% | Jun 30, 25 | 
| 4 | Pale Fire Capital SE | 2.64M (1.65%) | 47.80K  Increased by +1.81% | Jun 30, 25 | 
| 5 | Walleye Trading Advisors, LLC | 2.26M (1.41%) | -497.85K  Decreased by -21.98% | Sep 30, 24 | 
| 6 | Davidson Kempner Capital Management LP | 1.41M (0.88%) | 464.07K  Increased by +32.83% | Mar 31, 25 | 
| 7 | Millennium Management LLC | 1.19M (0.74%) | 52.41K  Increased by +4.41% | Jun 30, 25 | 
| 8 | Citadel Advisors Llc | 1.18M (0.74%) | 1.15M  Increased by +97.88% | Jun 30, 25 | 
| 9 | Moore Capital Management, LP | 952.38K (0.59%) | 0.00  Increased by 0.00% | Jun 30, 25 | 
| 10 | Brown University | 718.50K (0.45%) | 0.00  Increased by 0.00% | Jun 30, 25 | 
| 11 | D. E. Shaw & Co LP | 695.03K (0.43%) | -298.33K  Decreased by -42.92% | Jun 30, 25 | 
| 12 | Mirae Asset Global Investments (Korea) Co Ltd | 623.68K (0.39%) | -8.03K  Decreased by -1.29% | Dec 31, 23 | 
| 13 | Two Sigma Investments LLC | 510.06K (0.32%) | 138.10K  Increased by +27.07% | Jun 30, 25 | 
| 14 | Vanguard Group Inc | 436.93K (0.27%) | 47.75K  Increased by +10.93% | Jun 30, 25 | 
| 15 | AdvisorShares Investments, LLC | 389.76K (0.24%) | -19.00K  Decreased by -4.87% | Jun 30, 25 | 
| 16 | Franklin Resources Inc | 356.36K (0.22%) | 0.00  Increased by 0.00% | Jun 30, 25 | 
| 17 | Goldman Sachs Group Inc | 347.87K (0.22%) | 249.23K  Increased by +71.64% | Jun 30, 25 | 
| 18 | JPMorgan Chase & Co | 318.01K (0.20%) | 178.13K  Increased by +56.01% | Dec 31, 23 | 
| 19 | Cresset Asset Management, LLC | 311.61K (0.19%) | 0.00  Increased by 0.00% | Dec 31, 23 | 
| 20 | BlackRock Inc | 309.04K (0.19%) | -5.42K  Decreased by -1.76% | Mar 31, 25 | 
| Rank | Holder | SharesFloat % | Change | Date reported | 
|---|---|---|---|---|
| 1 | ARK Genomic Revolution ETF | 1.57M (0.98%) | -5.59K  Decreased by -0.36% | Aug 28, 25 | 
| 2 | Candriam Eqs L Biotech C USD Cap | 1.17M (0.73%) | 1.17M  Increased by +100.00% | Jul 31, 25 | 
| 3 | iShares Biotechnology ETF | 778.92K (0.49%) | 792.00  Increased by +0.10% | Nov 27, 24 | 
| 4 | Horizons Psychedelic Stock ETF | 520.20K (0.32%) | -82.78K  Decreased by -15.91% | Feb 29, 24 | 
| 5 | Morgan Stanley Inception | 511.99K (0.32%) | 0.00  Increased by 0.00% | Jun 30, 25 | 
| 6 | Morgan Stanley Inst Inception I | 511.99K (0.32%) | 0.00  Increased by 0.00% | Jun 30, 25 | 
| 7 | AdvisorShares Psychedelics ETF | 450.35K (0.28%) | 0.00  Increased by 0.00% | Aug 29, 25 | 
| 8 | Kieger Impact Healthcare A USD Acc | 438.30K (0.27%) | 0.00  Increased by 0.00% | Apr 30, 24 | 
| 9 | Vanguard Health Care ETF | 432.04K (0.27%) | -4.90K  Decreased by -1.13% | Jul 31, 25 | 
| 10 | EQ/Morgan Stanley Small Cap Growth K | 316.73K (0.20%) | 0.00  Increased by 0.00% | Jul 31, 25 | 
| 11 | Kairos Intl SICAV Opports L/S P | 212.70K (0.13%) | 212.70K  Increased by +100.00% | Jun 30, 24 | 
| 12 | iShares Healthcare Innov ETF USD Acc | 206.23K (0.13%) | 0.00  Increased by 0.00% | May 31, 25 | 
| 13 | Avantis US Small Cap Equity ETF | 206.16K (0.13%) | 0.00  Increased by 0.00% | Aug 30, 25 | 
| 14 | Fidelity Nasdaq Composite Index | 144.37K (0.09%) | 589.00  Increased by +0.41% | Jul 31, 25 | 
| 15 | iShares Nasdaq US Biotech ETF USD Acc | 98.96K (0.06%) | 0.00  Increased by 0.00% | Nov 27, 24 | 
| 16 | iShares Ageing Population ETF USD Acc | 81.67K (0.05%) | 0.00  Increased by 0.00% | May 31, 25 | 
| 17 | WEALTHGATE Biotech Fund Inst | 62.15K (0.04%) | 14.47K  Increased by +23.28% | Jun 30, 24 | 
| 18 | Vanguard Global Small-Cap Idx USD Acc | 54.39K (0.03%) | 0.00  Increased by 0.00% | Nov 30, 23 | 
| 19 | Rainbow Diversified Market Opports A | 50.00K (0.03%) | 0.00  Increased by 0.00% | Dec 31, 23 | 
| 20 | SPDR® S&P International Small Cap ETF | 42.16K (0.03%) | 0.00  Increased by 0.00% | Apr 30, 24 |