| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | UBS Group AG | 7.68M (2.53%) | -22.47K Decreased by -0.29% | Sep 30, 25 |
| 2 | Adage Capital Partners Gp LLC | 5.43M (1.79%) | 5.43M Increased by +100.00% | Jun 30, 25 |
| 3 | Morgan Stanley - Brokerage Accounts | 4.82M (1.59%) | 1.32M Increased by +27.44% | Sep 30, 25 |
| 4 | ARK Investment Management LLC | 3.31M (1.09%) | 1.29M Increased by +38.91% | Dec 31, 25 |
| 5 | Marshall Wace Asset Management Ltd | 2.68M (0.88%) | 1.61M Increased by +60.16% | Dec 31, 25 |
| 6 | Citadel Advisors Llc | 2.58M (0.85%) | 1.40M Increased by +54.21% | Sep 30, 25 |
| 7 | Walleye Trading Advisors, LLC | 2.26M (0.75%) | -497.85K Decreased by -21.98% | Sep 30, 24 |
| 8 | T. Rowe Price Investment Management,Inc. | 1.94M (0.64%) | 1.94M Increased by +100.00% | Sep 30, 25 |
| 9 | Ally Bridge Group (NY) LLC | 1.71M (0.57%) | -573.90K Decreased by -33.50% | Dec 31, 25 |
| 10 | JPMorgan Chase & Co | 1.54M (0.51%) | 1.53M Increased by +99.13% | Sep 30, 25 |
| 11 | Davidson Kempner Capital Management LP | 1.41M (0.47%) | 464.07K Increased by +32.83% | Mar 31, 25 |
| 12 | Millennium Management LLC | 1.10M (0.36%) | -90.40K Decreased by -8.23% | Sep 30, 25 |
| 13 | Pale Fire Capital SE | 1.08M (0.36%) | -1.56M Decreased by -144.31% | Sep 30, 25 |
| 14 | Moore Capital Management, LP | 952.38K (0.31%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 15 | Brown University | 718.50K (0.24%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 16 | D. E. Shaw & Co LP | 695.03K (0.23%) | -298.33K Decreased by -42.92% | Jun 30, 25 |
| 17 | CenterBook Partners LP | 651.13K (0.21%) | 651.13K Increased by +100.00% | Sep 30, 25 |
| 18 | Mirae Asset Global Investments (Korea) Co Ltd | 623.68K (0.21%) | -8.03K Decreased by -1.29% | Dec 31, 23 |
| 19 | Group One Trading, LP | 600.51K (0.20%) | 562.75K Increased by +93.71% | Sep 30, 25 |
| 20 | Jane Street Group LLC | 597.27K (0.20%) | 500.73K Increased by +83.84% | Sep 30, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | ARK Genomic Revolution ETF | 3.89M (1.29%) | 632.20K Increased by +16.24% | Feb 28, 26 |
| 2 | ARK Genomic Revolution | 3.17M (1.05%) | 1.21M Increased by +38.24% | Dec 31, 25 |
| 3 | iShares Biotechnology ETF | 2.05M (0.68%) | 0.00 Increased by 0.00% | Feb 28, 26 |
| 4 | Candriam Eqs L Biotech C USD Cap | 1.72M (0.57%) | 190.54K Increased by +11.07% | Oct 31, 25 |
| 5 | HBM Healthcare Investments AG Ord | 1.50M (0.50%) | 1.50M Increased by +100.00% | Dec 31, 25 |
| 6 | Columbia Acorn Inst | 909.73K (0.30%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 7 | Morgan Stanley Inception | 843.39K (0.28%) | 19.43K Increased by +2.30% | Dec 31, 25 |
| 8 | Morgan Stanley Inst Inception I | 843.39K (0.28%) | -130.65K Decreased by -15.49% | Dec 31, 25 |
| 9 | EQ/Morgan Stanley Small Cap Growth K | 578.62K (0.19%) | 113.34K Increased by +19.59% | Jan 31, 26 |
| 10 | AdvisorShares Psychedelics ETF | 567.59K (0.19%) | 0.00 Increased by 0.00% | Feb 27, 26 |
| 11 | Horizons Psychedelic Stock ETF | 520.20K (0.17%) | -82.78K Decreased by -15.91% | Feb 29, 24 |
| 12 | Kieger Impact Healthcare A USD Acc | 438.30K (0.14%) | 0.00 Increased by 0.00% | Apr 30, 24 |
| 13 | Vanguard Health Care ETF | 432.04K (0.14%) | -4.90K Decreased by -1.13% | Jul 31, 25 |
| 14 | iShares Nasdaq US Biotech ETF USD Acc | 268.11K (0.09%) | 163.51K Increased by +60.99% | Feb 28, 26 |
| 15 | Fidelity Nasdaq Composite Index | 217.81K (0.07%) | 0.00 Increased by 0.00% | Jan 31, 26 |
| 16 | Kairos Intl SICAV Opports L/S P | 212.70K (0.07%) | 212.70K Increased by +100.00% | Jun 30, 24 |
| 17 | iShares Healthcare Innov ETF USD Acc | 206.23K (0.07%) | 0.00 Increased by 0.00% | May 31, 25 |
| 18 | Avantis US Small Cap Equity ETF | 206.16K (0.07%) | 0.00 Increased by 0.00% | Aug 30, 25 |
| 19 | Nuveen ESG Small-Cap ETF | 175.83K (0.06%) | 0.00 Increased by 0.00% | Feb 28, 26 |
| 20 | Columbia VP Acorn | 173.06K (0.06%) | 0.00 Increased by 0.00% | Dec 31, 25 |