| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Group Inc | 9.39M (15.10%) | 1.03M Increased by +10.98% | Jun 30, 25 |
| 2 | EcoR1 Capital, LLC | 6.73M (10.81%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 3 | BlackRock Inc | 6.17M (9.92%) | -396.54K Decreased by -6.43% | Mar 31, 25 |
| 4 | Citadel Advisors Llc | 3.88M (6.23%) | 803.18K Increased by +20.72% | Mar 31, 25 |
| 5 | Pfizer Inc | 3.46M (5.56%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 6 | RTW INVESTMENTS, LLC | 3.33M (5.36%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 7 | Bellevue Group AG | 2.39M (3.84%) | 3.00K Increased by +0.13% | Dec 31, 24 |
| 8 | Paradigm Biocapital Advisors LP | 2.34M (3.76%) | -98.19K Decreased by -4.20% | Sep 30, 24 |
| 9 | T. Rowe Price Investment Management,Inc. | 2.21M (3.55%) | 2.21M Increased by +100.00% | Dec 31, 24 |
| 10 | D. E. Shaw & Co LP | 2.15M (3.46%) | 2.15M Increased by +100.00% | Jun 30, 25 |
| 11 | UBS Group AG | 2.04M (3.28%) | 1.57M Increased by +76.87% | Dec 31, 24 |
| 12 | State Street Corp | 1.90M (3.05%) | 259.14K Increased by +13.67% | Mar 31, 25 |
| 13 | JPMorgan Chase & Co | 1.86M (2.99%) | -2.80M Decreased by -150.86% | Dec 31, 24 |
| 14 | Alyeska Investment Group, L.P. | 1.80M (2.89%) | 1.80M Increased by +100.00% | Mar 31, 25 |
| 15 | ArrowMark Colorado Holdings, LLC (ArrowMark Partners) | 1.78M (2.86%) | 532.11K Increased by +29.95% | Dec 31, 24 |
| 16 | Opaleye Management Inc | 1.68M (2.70%) | -295.00K Decreased by -17.56% | Jun 30, 25 |
| 17 | New Leaf Venture Partners, L.L.C. | 1.59M (2.55%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 18 | FMR Inc | 1.56M (2.51%) | -1.32M Decreased by -84.99% | Dec 31, 24 |
| 19 | Geode Capital Management, LLC | 1.54M (2.47%) | 25.78K Increased by +1.68% | Mar 31, 25 |
| 20 | Nextech Invest AG | 1.41M (2.26%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | BB Biotech AG Ord | 2.38M (3.83%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 2 | Vanguard Total Stock Mkt Idx Inv | 2.01M (3.23%) | -44.64K Decreased by -2.22% | Jul 31, 25 |
| 3 | Vanguard US Total Market Shares ETF | 1.93M (3.11%) | 2.43K Increased by +0.13% | Sep 30, 24 |
| 4 | iShares Russell 2000 ETF | 1.56M (2.51%) | -29.71K Decreased by -1.90% | Jul 31, 25 |
| 5 | Vanguard Explorer Inv | 1.56M (2.50%) | 683.33K Increased by +43.94% | Jun 30, 25 |
| 6 | Vanguard Strategic Equity Inv | 1.25M (2.01%) | 594.88K Increased by +47.68% | Jun 30, 25 |
| 7 | Vanguard Small Cap Index | 841.18K (1.35%) | -5.64K Decreased by -0.67% | Jul 31, 25 |
| 8 | JPMorgan Small Cap Growth A | 755.08K (1.21%) | -8.49K Decreased by -1.12% | Feb 28, 25 |
| 9 | Vanguard Institutional Extnd Mkt Idx Tr | 747.55K (1.20%) | -326.16K Decreased by -43.63% | Jul 31, 25 |
| 10 | T. Rowe Price New Horizons | 715.98K (1.15%) | -299.48K Decreased by -41.83% | Jun 30, 25 |
| 11 | US Small-Cap Growth II Equity Comp | 715.98K (1.15%) | -1.17M Decreased by -163.57% | Jun 30, 25 |
| 12 | Vanguard Strategic Small-Cap Equity Inv | 713.32K (1.15%) | 459.94K Increased by +64.48% | Jun 30, 25 |
| 13 | T. Rowe Price Small-Cap Stock | 702.69K (1.13%) | 94.70K Increased by +13.48% | Feb 28, 25 |
| 14 | Fidelity Small Cap Index | 653.83K (1.05%) | 99.91K Increased by +15.28% | May 31, 25 |
| 15 | FIAM Small Cap Core Composite | 601.40K (0.97%) | -165.20K Decreased by -27.47% | Dec 31, 24 |
| 16 | FIAM Small Cap Core CIT Cl B | 587.40K (0.94%) | -14.00K Decreased by -2.38% | Feb 28, 25 |
| 17 | iShares Russell 2000 Growth ETF | 555.88K (0.89%) | 0.00 Increased by 0.00% | May 31, 25 |
| 18 | T. Rowe Price New Horizons Tr-A | 525.56K (0.84%) | 757.00 Increased by +0.14% | Mar 31, 25 |
| 19 | T. Rowe Price New Horizons Tr-Z | 525.56K (0.84%) | 757.00 Increased by +0.14% | Mar 31, 25 |
| 20 | iShares Russell 2000 Value ETF | 508.24K (0.82%) | 377.00 Increased by +0.07% | Jul 31, 25 |