| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | EcoR1 Capital, LLC | 5.47M (9.78%) | 1.45M Increased by +26.51% | Sep 30, 23 |
| 2 | BlackRock Inc | 4.97M (8.89%) | 66.14K Increased by +1.33% | Sep 30, 23 |
| 3 | FMR Inc | 4.87M (8.71%) | 466.67K Increased by +9.59% | Sep 30, 23 |
| 4 | Vanguard Group Inc | 4.61M (8.25%) | 90.43K Increased by +1.96% | Sep 30, 23 |
| 5 | T. Rowe Price Associates, Inc. | 3.83M (6.86%) | 1.14M Increased by +29.84% | Dec 31, 23 |
| 6 | Avidity Partners Management LP | 2.99M (5.34%) | 370.16K Increased by +12.4% | Dec 31, 23 |
| 7 | Bellevue Group AG | 2.51M (4.49%) | 382.53K Increased by +15.25% | Dec 31, 23 |
| 8 | JPMorgan Chase & Co | 1.99M (3.56%) | -8.98K Decreased by -0.45% | Sep 30, 23 |
| 9 | ArrowMark Colorado Holdings, LLC (ArrowMark Partners) | 1.57M (2.81%) | -517.4K Decreased by -32.96% | Dec 31, 23 |
| 10 | New Leaf Venture Partners, L.L.C. | 1.29M (2.31%) | 0 Increased by 0% | Sep 30, 23 |
| 11 | State Street Corporation | 1.16M (2.08%) | 42.61K Increased by +3.67% | Sep 30, 23 |
| 12 | Geode Capital Management, LLC | 1.06M (1.89%) | 62.42K Increased by +5.9% | Sep 30, 23 |
| 13 | NORGES BANK | 877.71K (1.57%) | 175.95K Increased by +20.05% | Dec 31, 23 |
| 14 | Millennium Management LLC | 828.13K (1.48%) | 421.97K Increased by +50.95% | Sep 30, 23 |
| 15 | American Century Companies Inc | 813.47K (1.46%) | -46.51K Decreased by -5.72% | Sep 30, 23 |
| 16 | Adage Capital Partners Gp LLC | 789.49K (1.41%) | 789.49K Increased by +100% | Dec 31, 23 |
| 17 | Citadel Advisors Llc | 624.58K (1.12%) | -265.02K Decreased by -42.43% | Sep 30, 23 |
| 18 | Finepoint Capital LP | 504.7K (0.9%) | 93.2K Increased by +18.47% | Sep 30, 23 |
| 19 | Dimensional Fund Advisors, Inc. | 491.88K (0.88%) | 22.48K Increased by +4.57% | Dec 31, 23 |
| 20 | Aquilo Capital Management, LLC | 489.15K (0.88%) | -134.79K Decreased by -27.56% | Sep 30, 23 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | BB Biotech AG Ord | 2.12M (3.79%) | 0 Increased by 0% | Sep 30, 23 |
| 2 | T. Rowe Price New Horizons | 1.76M (3.15%) | 513.96K Increased by +29.2% | Dec 31, 23 |
| 3 | US Small-Cap Growth II Equity Comp | 1.76M (3.15%) | 513.53K Increased by +29.17% | Dec 31, 23 |
| 4 | Vanguard Total Stock Mkt Idx Inv | 1.46M (2.61%) | 36.2K Increased by +2.48% | Jan 31, 24 |
| 5 | iShares Russell 2000 ETF | 1.21M (2.17%) | -22.12K Decreased by -1.82% | Jan 31, 24 |
| 6 | Vanguard Small Cap Index | 1.19M (2.14%) | 3.31K Increased by +0.28% | Jan 31, 24 |
| 7 | FIAM Small Cap Core CIT Cl B | 995.7K (1.78%) | 0 Increased by 0% | Nov 30, 23 |
| 8 | FIAM Small Cap Core Composite | 985K (1.76%) | 521K Increased by +52.89% | Sep 30, 23 |
| 9 | JPM Global Healthcare C (acc) USD | 902.23K (1.61%) | 0 Increased by 0% | Jan 31, 24 |
| 10 | T. Rowe Price Health Sciences | 850.24K (1.52%) | 366.24K Increased by +43.07% | Dec 31, 23 |
| 11 | Vanguard Institutional Extnd Mkt Idx Tr | 811.38K (1.45%) | 292 Increased by +0.04% | Jan 31, 24 |
| 12 | Vanguard Explorer Inv | 724K (1.3%) | -95.76K Decreased by -13.23% | Dec 31, 23 |
| 13 | JPMorgan Small Cap Growth A | 676.32K (1.21%) | -15.93K Decreased by -2.36% | Dec 31, 23 |
| 14 | Vanguard Small Cap Growth Index Inv | 665.39K (1.19%) | 122 Increased by +0.02% | Jan 31, 24 |
| 15 | Fidelity Small Cap Index | 483.25K (0.86%) | 8.57K Increased by +1.77% | Nov 30, 23 |
| 16 | Fidelity® Small Cap Index | 474.69K (0.85%) | 13.34K Increased by +2.81% | Oct 31, 23 |
| 17 | iShares Russell 2000 Growth ETF | 404.63K (0.72%) | 474 Increased by +0.12% | Jan 31, 24 |
| 18 | Nomura ACI AdvMed Impact Inv MF | 352.3K (0.63%) | 28.89K Increased by +8.2% | Jun 19, 23 |
| 19 | iShares Biotechnology ETF | 351.16K (0.63%) | -322 Decreased by -0.09% | Jan 31, 24 |
| 20 | Belfius Equities Cure C Cap | 348.25K (0.62%) | 0 Increased by 0% | Jan 31, 24 |