| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Group Inc | 7.01M (12.25%) | 334.18K Increased by +4.77% | Sep 30, 24 |
| 2 | EcoR1 Capital, LLC | 6.73M (11.76%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 3 | BlackRock Inc | 6.26M (10.94%) | 764.55K Increased by +12.22% | Jun 30, 24 |
| 4 | T. Rowe Price Associates, Inc. | 3.85M (6.74%) | -135.15K Decreased by -3.51% | Sep 30, 24 |
| 5 | FMR Inc | 2.88M (5.04%) | 204.32K Increased by +7.09% | Sep 30, 24 |
| 6 | RTW INVESTMENTS, LLC | 2.78M (4.87%) | -185.57K Decreased by -6.67% | Sep 30, 24 |
| 7 | Citadel Advisors Llc | 2.71M (4.73%) | 68.05K Increased by +2.51% | Sep 30, 24 |
| 8 | Bellevue Group AG | 2.39M (4.17%) | -4.20K Decreased by -0.18% | Sep 30, 24 |
| 9 | Paradigm Biocapital Advisors LP | 2.34M (4.09%) | -98.19K Decreased by -4.20% | Sep 30, 24 |
| 10 | JPMorgan Chase & Co | 2.33M (4.07%) | 367.34K Increased by +15.77% | Sep 30, 24 |
| 11 | State Street Corp | 1.64M (2.87%) | -55.96K Decreased by -3.40% | Sep 30, 24 |
| 12 | Morgan Stanley - Brokerage Accounts | 1.56M (2.73%) | 208.56K Increased by +13.37% | Jun 30, 24 |
| 13 | Geode Capital Management, LLC | 1.52M (2.66%) | -22.40K Decreased by -1.47% | Sep 30, 24 |
| 14 | Avidity Partners Management LP | 1.50M (2.62%) | -1.49M Decreased by -99.59% | Sep 30, 24 |
| 15 | New Leaf Venture Partners, L.L.C. | 1.43M (2.51%) | 145.20K Increased by +10.12% | Sep 30, 24 |
| 16 | Nextech Invest AG | 1.41M (2.46%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 17 | State Street Corporation | 1.38M (2.42%) | 195.69K Increased by +14.16% | Mar 31, 24 |
| 18 | BRAIDWELL LP | 1.28M (2.25%) | 767.24K Increased by +59.73% | Sep 30, 24 |
| 19 | Opaleye Management Inc | 1.25M (2.19%) | 700.00K Increased by +55.78% | Sep 30, 24 |
| 20 | ArrowMark Colorado Holdings, LLC (ArrowMark Partners) | 1.24M (2.18%) | 17.72K Increased by +1.42% | Sep 30, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | BB Biotech AG Ord | 2.38M (4.16%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 2 | T. Rowe Price New Horizons | 2.02M (3.53%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 3 | US Small-Cap Growth II Equity Comp | 2.02M (3.53%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 4 | Vanguard Total Stock Mkt Idx Inv | 1.92M (3.35%) | -17.33K Decreased by -0.90% | Oct 31, 24 |
| 5 | iShares Russell 2000 ETF | 1.78M (3.12%) | -3.72K Decreased by -0.21% | Nov 27, 24 |
| 6 | Vanguard Small Cap Index | 1.55M (2.71%) | 3.05K Increased by +0.20% | Oct 31, 24 |
| 7 | Vanguard Institutional Extnd Mkt Idx Tr | 974.22K (1.70%) | -2.91K Decreased by -0.30% | Oct 31, 24 |
| 8 | Vanguard Explorer Inv | 933.24K (1.63%) | 185.74K Increased by +19.90% | Sep 30, 24 |
| 9 | Vanguard Small Cap Growth Index Inv | 853.33K (1.49%) | 476.00 Increased by +0.06% | Oct 31, 24 |
| 10 | FIAM Small Cap Core CIT Cl B | 794.80K (1.39%) | 10.30K Increased by +1.30% | Aug 31, 24 |
| 11 | JPMorgan Small Cap Growth A | 791.92K (1.38%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 12 | Fidelity Small Cap Index | 658.11K (1.15%) | -16.27K Decreased by -2.47% | Aug 31, 24 |
| 13 | FIAM Small Cap Core Composite | 628.40K (1.10%) | -30.60K Decreased by -4.87% | Jun 30, 24 |
| 14 | iShares Russell 2000 Growth ETF | 581.59K (1.02%) | 0.00 Increased by 0.00% | Nov 27, 24 |
| 15 | JPM Global Healthcare C (acc) USD | 479.22K (0.84%) | 0.00 Increased by 0.00% | Oct 31, 24 |
| 16 | UBS: US Equity Small Cap Growth | 479.11K (0.84%) | 147.20K Increased by +30.72% | Dec 31, 23 |
| 17 | Fidelity® Small Cap Index | 474.69K (0.83%) | 13.34K Increased by +2.81% | Oct 31, 23 |
| 18 | T. Rowe Price New Horizons Tr-Z | 445.63K (0.78%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 19 | T. Rowe Price Health Sciences | 428.03K (0.75%) | -8.04K Decreased by -1.88% | Sep 30, 24 |
| 20 | Strategic Advisers Fidelity US TtlStk | 415.23K (0.73%) | 15.80K Increased by +3.81% | Sep 30, 24 |