| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Group Inc | 7.06M (10.85%) | 56.56K Increased by +0.80% | Dec 31, 24 |
| 2 | EcoR1 Capital, LLC | 6.73M (10.33%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 3 | BlackRock Inc | 6.57M (10.09%) | 70.06K Increased by +1.07% | Dec 31, 24 |
| 4 | T. Rowe Price Associates, Inc. | 4.10M (6.30%) | 249.29K Increased by +6.08% | Dec 31, 24 |
| 5 | Pfizer Inc | 3.46M (5.31%) | 3.46M Increased by +100.00% | Dec 31, 24 |
| 6 | RTW INVESTMENTS, LLC | 3.33M (5.12%) | 551.98K Increased by +16.55% | Dec 31, 24 |
| 7 | Citadel Advisors Llc | 3.07M (4.72%) | 365.12K Increased by +11.88% | Dec 31, 24 |
| 8 | Bellevue Group AG | 2.39M (3.67%) | 3.00K Increased by +0.13% | Dec 31, 24 |
| 9 | Paradigm Biocapital Advisors LP | 2.34M (3.59%) | -98.19K Decreased by -4.20% | Sep 30, 24 |
| 10 | T. Rowe Price Investment Management,Inc. | 2.21M (3.39%) | 2.21M Increased by +100.00% | Dec 31, 24 |
| 11 | UBS Group AG | 2.04M (3.13%) | 1.57M Increased by +76.87% | Dec 31, 24 |
| 12 | JPMorgan Chase & Co | 1.86M (2.85%) | -2.80M Decreased by -150.86% | Dec 31, 24 |
| 13 | ArrowMark Colorado Holdings, LLC (ArrowMark Partners) | 1.78M (2.73%) | 532.11K Increased by +29.95% | Dec 31, 24 |
| 14 | State Street Corp | 1.64M (2.51%) | -6.68K Decreased by -0.41% | Dec 31, 24 |
| 15 | Opaleye Management Inc | 1.63M (2.50%) | 370.00K Increased by +22.77% | Dec 31, 24 |
| 16 | New Leaf Venture Partners, L.L.C. | 1.59M (2.44%) | 151.00K Increased by +9.52% | Dec 31, 24 |
| 17 | FMR Inc | 1.56M (2.39%) | -1.32M Decreased by -84.99% | Dec 31, 24 |
| 18 | Geode Capital Management, LLC | 1.51M (2.32%) | -8.32K Decreased by -0.55% | Dec 31, 24 |
| 19 | Nextech Invest AG | 1.41M (2.16%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 20 | State Street Corporation | 1.38M (2.12%) | 195.69K Increased by +14.16% | Mar 31, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | BB Biotech AG Ord | 2.38M (3.66%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 2 | Vanguard Total Stock Mkt Idx Inv | 1.94M (2.98%) | -144.00 Decreased by -0.01% | Mar 31, 25 |
| 3 | Vanguard US Total Market Shares ETF | 1.93M (2.97%) | 2.43K Increased by +0.13% | Sep 30, 24 |
| 4 | T. Rowe Price New Horizons | 1.89M (2.90%) | -128.42K Decreased by -6.81% | Mar 31, 25 |
| 5 | US Small-Cap Growth II Equity Comp | 1.89M (2.90%) | -129.00K Decreased by -6.84% | Mar 31, 25 |
| 6 | iShares Russell 2000 ETF | 1.59M (2.44%) | -12.86K Decreased by -0.81% | Apr 29, 25 |
| 7 | Vanguard Small Cap Index | 1.54M (2.37%) | -36.11K Decreased by -2.34% | Mar 31, 25 |
| 8 | Vanguard Institutional Extnd Mkt Idx Tr | 1.00M (1.54%) | 39.24K Increased by +3.91% | Mar 31, 25 |
| 9 | Vanguard Explorer Inv | 871.97K (1.34%) | -332.49K Decreased by -38.13% | Mar 31, 25 |
| 10 | Vanguard Small Cap Growth Index Inv | 863.71K (1.33%) | -21.02K Decreased by -2.43% | Mar 31, 25 |
| 11 | JPMorgan Small Cap Growth A | 755.08K (1.16%) | -8.49K Decreased by -1.12% | Feb 28, 25 |
| 12 | T. Rowe Price Small-Cap Stock | 702.69K (1.08%) | 94.70K Increased by +13.48% | Feb 28, 25 |
| 13 | Vanguard Strategic Equity Inv | 652.73K (1.00%) | 312.58K Increased by +47.89% | Mar 31, 25 |
| 14 | Fidelity Small Cap Index | 642.09K (0.99%) | 8.70K Increased by +1.35% | Feb 28, 25 |
| 15 | Federated Hermes MDT Small Cap Core IS | 610.45K (0.94%) | 579.01K Increased by +94.85% | Mar 31, 25 |
| 16 | FIAM Small Cap Core Composite | 601.40K (0.92%) | -165.20K Decreased by -27.47% | Dec 31, 24 |
| 17 | FIAM Small Cap Core CIT Cl B | 587.40K (0.90%) | -14.00K Decreased by -2.38% | Feb 28, 25 |
| 18 | iShares Russell 2000 Growth ETF | 573.57K (0.88%) | 0.00 Increased by 0.00% | Apr 30, 25 |
| 19 | T. Rowe Price New Horizons Tr-Z | 525.56K (0.81%) | 757.00 Increased by +0.14% | Mar 31, 25 |
| 20 | T. Rowe Price New Horizons Tr-A | 524.80K (0.81%) | 79.17K Increased by +15.09% | Dec 31, 24 |