| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | BlackRock Inc | 20.75M (8.94%) | 2.80M Increased by +13.49% | Jun 30, 25 |
| 2 | Vanguard Group Inc | 16.03M (6.91%) | 1.03M Increased by +6.45% | Jun 30, 25 |
| 3 | HHG PLC | 15.06M (6.49%) | -9.92M Decreased by -65.87% | Jun 30, 25 |
| 4 | State Street Corporation | 14.09M (6.07%) | -3.01M Decreased by -21.39% | Mar 31, 24 |
| 5 | Millennium Management LLC | 11.66M (5.03%) | 5.20M Increased by +44.57% | Jun 30, 25 |
| 6 | Macquarie Group Ltd | 11.46M (4.94%) | 299.42K Increased by +2.61% | Jun 30, 25 |
| 7 | Marshall Wace Asset Management Ltd | 11.25M (4.85%) | 2.87M Increased by +25.48% | Jun 30, 25 |
| 8 | State Street Corp | 9.84M (4.24%) | -334.65K Decreased by -3.40% | Jun 30, 25 |
| 9 | Geode Capital Management, LLC | 5.67M (2.44%) | -6.52K Decreased by -0.12% | Jun 30, 25 |
| 10 | Eventide Asset Management, LLC | 5.60M (2.41%) | -1.81M Decreased by -32.36% | Dec 31, 24 |
| 11 | Bank of America Corp | 5.53M (2.38%) | 2.60M Increased by +47.03% | Jun 30, 25 |
| 12 | Goldman Sachs Group Inc | 4.00M (1.73%) | 1.62M Increased by +40.58% | Jun 30, 25 |
| 13 | Nuveen, LLC | 3.49M (1.50%) | 81.50K Increased by +2.34% | Jun 30, 25 |
| 14 | VOLORIDGE INVESTMENT MANAGEMENT, LLC | 2.89M (1.24%) | -414.88K Decreased by -14.37% | Jun 30, 24 |
| 15 | Adage Capital Partners Gp LLC | 2.60M (1.12%) | 300.00K Increased by +11.54% | Dec 31, 23 |
| 16 | D. E. Shaw & Co LP | 2.46M (1.06%) | 542.14K Increased by +22.05% | Jun 30, 25 |
| 17 | Jane Street Group LLC | 2.45M (1.05%) | 1.22M Increased by +49.79% | Mar 31, 25 |
| 18 | Oracle Investment Management Inc | 2.40M (1.04%) | 315.01K Increased by +13.10% | Mar 31, 25 |
| 19 | Morgan Stanley - Brokerage Accounts | 2.34M (1.01%) | -862.73K Decreased by -36.81% | Jun 30, 25 |
| 20 | Amvescap Plc. | 2.33M (1.01%) | 970.15K Increased by +41.58% | Dec 31, 23 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Macquarie Small Cap Core I | 8.61M (3.71%) | -646.97K Decreased by -7.51% | Jul 31, 25 |
| 2 | Delaware Small Cap Core I | 7.32M (3.15%) | 0.00 Increased by 0.00% | Oct 31, 24 |
| 3 | Vanguard Total Stock Mkt Idx Inv | 7.10M (3.06%) | -157.53K Decreased by -2.22% | Jul 31, 25 |
| 4 | Vanguard US Total Market Shares ETF | 7.03M (3.03%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 5 | iShares Russell 2000 ETF | 5.70M (2.46%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 6 | SPDR® S&P Biotech ETF | 4.38M (1.89%) | 9.78K Increased by +0.22% | Aug 31, 25 |
| 7 | Janus Selection Global Life Science AUSD | 3.62M (1.56%) | -114.93K Decreased by -3.17% | Mar 31, 24 |
| 8 | Janus Henderson Global Life Sciences | 3.24M (1.40%) | -909.95K Decreased by -28.09% | Jun 30, 25 |
| 9 | Janus Henderson Global Life Sciences D | 3.24M (1.40%) | -126.95K Decreased by -3.92% | Jun 30, 25 |
| 10 | Delaware US Small Cap Core Equity (SMA) | 3.06M (1.32%) | 3.06M Increased by +100.00% | Mar 31, 24 |
| 11 | Macquarie US Small Cap Core Equity | 3.06M (1.32%) | 3.06M Increased by +100.00% | Mar 31, 24 |
| 12 | Eventide Healthcare & Life Sciences I | 3.02M (1.30%) | -1.82M Decreased by -60.24% | Dec 31, 24 |
| 13 | T. Rowe Price Health Sciences | 2.95M (1.27%) | 1.26M Increased by +42.86% | Mar 31, 24 |
| 14 | Janus Global Life Science AUSD | 2.69M (1.16%) | -671.50K Decreased by -25.00% | Jun 30, 25 |
| 15 | Janus Henderson Glb Life Scn I2 USD | 2.66M (1.15%) | -25.67K Decreased by -0.96% | Jul 31, 25 |
| 16 | Vanguard Institutional Extnd Mkt Idx Tr | 2.57M (1.11%) | -1.15M Decreased by -44.82% | Jul 31, 25 |
| 17 | Eventide Gilead N | 2.57M (1.11%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 18 | Janus Henderson US SMID Cap Growth MA | 2.49M (1.07%) | 2.49M Increased by +99.99% | Dec 31, 24 |
| 19 | Janus Henderson Triton D | 2.45M (1.06%) | 0.00 Increased by 0.00% | May 31, 25 |
| 20 | Janus Henderson US SMID Cap Growth | 2.45M (1.06%) | -39.03K Decreased by -1.59% | Mar 31, 25 |