| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | T. Rowe Price Investment Management,Inc. | 21.40M (17.86%) | 2.72M Increased by +12.71% | Sep 30, 25 |
| 2 | Vestal Point Capital LP | 11.50M (9.60%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 3 | Propel Bio Management LLC | 11.29M (9.42%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 4 | HHG PLC | 10.54M (8.80%) | 2.89M Increased by +27.45% | Sep 30, 24 |
| 5 | Perceptive Advisors LLC | 8.01M (6.68%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 6 | Vanguard Group Inc | 6.35M (5.30%) | 1.25M Increased by +19.68% | Dec 31, 25 |
| 7 | Knoll Capital Management LP | 6.05M (5.05%) | -1.75M Decreased by -28.92% | Dec 31, 25 |
| 8 | VR Adviser, LLC | 5.57M (4.65%) | -4.42M Decreased by -79.44% | Mar 31, 25 |
| 9 | Schonfeld Strategic Advisors LLC | 4.67M (3.90%) | -4.09M Decreased by -87.48% | Mar 31, 25 |
| 10 | Simplify Asset Management Inc. | 4.49M (3.74%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 11 | Deltec Asset Management LLC | 3.85M (3.21%) | 3.85M Increased by +100.00% | Dec 31, 25 |
| 12 | BlackRock Inc | 3.84M (3.21%) | -1.38M Decreased by -35.80% | Sep 30, 25 |
| 13 | Armistice Capital, LLC | 3.40M (2.84%) | 3.40M Increased by +100.00% | Sep 30, 23 |
| 14 | Alyeska Investment Group, L.P. | 3.11M (2.59%) | 400.00K Increased by +12.87% | Mar 31, 25 |
| 15 | PNC Financial Services Group Inc | 2.90M (2.42%) | 2.90M Increased by +100.00% | Sep 30, 25 |
| 16 | Renaissance Technologies Corp | 2.71M (2.26%) | 2.71M Increased by +100.00% | Dec 31, 25 |
| 17 | Pathstone Holdings LLC | 2.64M (2.21%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 18 | Marshall Wace Asset Management Ltd | 2.54M (2.12%) | 998.50K Increased by +39.27% | Sep 30, 25 |
| 19 | TANG CAPITAL MANAGEMENT LLC | 2.43M (2.03%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 20 | FMR Inc | 2.43M (2.03%) | -212.10K Decreased by -8.74% | Dec 31, 23 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | T. Rowe Price Small-Cap Value | 12.66M (10.57%) | -12.02K Decreased by -0.09% | Jan 31, 26 |
| 2 | T. Rowe Price U.S. SC Value Eq Tr-D | 8.34M (6.96%) | 408.67K Increased by +4.90% | Dec 31, 25 |
| 3 | Simplify Propel Opportunities ETF | 4.49M (3.74%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 4 | T. Rowe Price U.S. SC Value Eq Tr-Z | 3.65M (3.04%) | 1.76M Increased by +48.34% | Mar 31, 25 |
| 5 | Vanguard US Total Market Shares ETF | 3.15M (2.63%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 6 | Vanguard Total Stock Mkt Idx Inv | 3.04M (2.54%) | -66.40K Decreased by -2.19% | Jul 31, 25 |
| 7 | Fidelity Select Biotechnology | 2.43M (2.03%) | 0.00 Increased by 0.00% | Dec 31, 23 |
| 8 | Fidelity® Select Biotechnology | 2.43M (2.03%) | -212.10K Decreased by -8.74% | Nov 30, 23 |
| 9 | SPDR® S&P Biotech ETF | 1.75M (1.46%) | -53.01K Decreased by -3.04% | Nov 27, 24 |
| 10 | Franklin Biotechnology Discv A(acc)USD | 1.26M (1.05%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 11 | Fidelity Small Cap Index | 1.05M (0.87%) | 0.00 Increased by 0.00% | May 31, 25 |
| 12 | Vanguard Institutional Extnd Mkt Idx Tr | 899.89K (0.75%) | -361.05K Decreased by -40.12% | Jul 31, 25 |
| 13 | Janus Henderson Hrzn Biotec E2 USD | 762.22K (0.64%) | 202.19K Increased by +26.53% | Sep 30, 24 |
| 14 | Franklin Biotechnology Discovery A | 740.20K (0.62%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 15 | iShares Biotechnology ETF | 733.05K (0.61%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 16 | Fidelity Extended Market Index | 713.27K (0.60%) | -1.38K Decreased by -0.19% | Dec 31, 25 |
| 17 | iShares Russell 2000 ETF | 681.61K (0.57%) | -23.35K Decreased by -3.43% | Jun 30, 25 |
| 18 | Xtrackers S&P 500 Swap ETF 1C | 617.67K (0.52%) | -4.56K Decreased by -0.74% | Dec 31, 25 |
| 19 | State St Russell Sm/Mid Cp® Indx NL Cl C | 574.79K (0.48%) | 0.00 Increased by 0.00% | Apr 30, 25 |
| 20 | State St Russell Sm/Mid Cp® Indx SL Cl I | 574.79K (0.48%) | 0.00 Increased by 0.00% | May 31, 25 |