| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | FMR Inc | 14.22M (18.57%) | 5.66M Increased by +39.81% | Dec 31, 24 |
| 2 | BlackRock Inc | 8.49M (11.08%) | 838.47K Increased by +9.88% | Dec 31, 24 |
| 3 | SATTER MANAGEMENT CO., L.P. | 7.41M (9.67%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 4 | Bvf Inc | 7.00M (9.14%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 5 | Redmile Group, LLC | 6.30M (8.23%) | -126.82K Decreased by -2.01% | Dec 31, 24 |
| 6 | Point72 Asset Management, L.P. | 5.63M (7.35%) | 299.80K Increased by +5.33% | Dec 31, 24 |
| 7 | Vanguard Group Inc | 5.55M (7.24%) | 576.63K Increased by +10.40% | Dec 31, 24 |
| 8 | Bain Capital Life Sciences Investors, LLC | 5.25M (6.85%) | -3.20M Decreased by -60.98% | Dec 31, 24 |
| 9 | Bellevue Group AG | 5.16M (6.73%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 10 | State Street Corp | 4.51M (5.89%) | 668.84K Increased by +14.83% | Dec 31, 24 |
| 11 | Adage Capital Partners Gp LLC | 2.84M (3.71%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 12 | Nuveen Asset Management, LLC | 2.72M (3.55%) | 164.91K Increased by +6.06% | Dec 31, 24 |
| 13 | Woodline Partners LP | 2.69M (3.51%) | -739.37K Decreased by -27.48% | Dec 31, 24 |
| 14 | Logos Global Management LP | 2.55M (3.33%) | -50.00K Decreased by -1.96% | Dec 31, 24 |
| 15 | Candriam Luxembourg S.C.A. | 2.53M (3.31%) | 341.43K Increased by +13.47% | Dec 31, 24 |
| 16 | Sio Capital Management, LLC | 2.37M (3.09%) | 933.85K Increased by +39.45% | Dec 31, 24 |
| 17 | Geode Capital Management, LLC | 2.17M (2.84%) | 27.84K Increased by +1.28% | Dec 31, 24 |
| 18 | Octagon Capital Advisors LP | 2.05M (2.68%) | 0.00 Increased by 0.00% | Mar 31, 24 |
| 19 | Morgan Stanley - Brokerage Accounts | 2.02M (2.63%) | 217.80K Increased by +10.80% | Jun 30, 24 |
| 20 | GMT Capital Corp | 1.91M (2.49%) | -1.03M Decreased by -54.06% | Sep 30, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | BB Biotech AG Ord | 5.16M (6.73%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 2 | Fidelity Growth Compy Commingled Pl S | 4.14M (5.41%) | 5.60K Increased by +0.14% | Feb 28, 25 |
| 3 | Vanguard Total Stock Mkt Idx Inv | 3.01M (3.93%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 4 | Fidelity Growth Company Fund | 2.98M (3.89%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 5 | Vanguard US Total Market Shares ETF | 2.83M (3.69%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 6 | iShares Russell 2000 ETF | 2.59M (3.39%) | -22.50K Decreased by -0.87% | Mar 31, 25 |
| 7 | Candriam Eqs L Biotech C USD Cap | 2.53M (3.31%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 8 | Fidelity Growth Compy Commingled Pl O | 2.37M (3.10%) | 0.00 Increased by 0.00% | Aug 31, 24 |
| 9 | SPDR® S&P Biotech ETF | 2.32M (3.03%) | -14.13K Decreased by -0.61% | Feb 28, 25 |
| 10 | CT (Lux) American Smaller Com 9U USD | 1.85M (2.41%) | 24.05K Increased by +1.30% | Feb 28, 25 |
| 11 | Vanguard Institutional Extnd Mkt Idx Tr | 1.38M (1.81%) | 40.48K Increased by +2.93% | Mar 31, 25 |
| 12 | Fidelity Small Cap Growth | 1.33M (1.74%) | 0.00 Increased by 0.00% | Jan 31, 25 |
| 13 | CREF Stock R1 | 1.23M (1.60%) | 148.81K Increased by +12.12% | Nov 30, 24 |
| 14 | Fidelity Select Health Care | 1.20M (1.57%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 15 | CT American Smaller Coms(US) InstAccGBP | 1.15M (1.50%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 16 | Eventide Healthcare & Life Sciences I | 1.02M (1.33%) | 1.02M Increased by +100.00% | Dec 31, 24 |
| 17 | Polar Capital Biotech S Inc | 1.00M (1.31%) | 0.00 Increased by 0.00% | Mar 31, 24 |
| 18 | Fidelity Small Cap Index | 959.13K (1.25%) | -17.96K Decreased by -1.87% | Jan 31, 25 |
| 19 | Fidelity Growth Company K6 | 900.01K (1.18%) | -22.90K Decreased by -2.54% | Feb 28, 25 |
| 20 | Rhenman Healthcare Equity L/S RC2 SEK | 900.00K (1.18%) | 0.00 Increased by 0.00% | Aug 31, 24 |