| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | FMR Inc | 13.26M (16.10%) | -962.05K Decreased by -7.25% | Mar 31, 25 |
| 2 | BlackRock Inc | 8.53M (10.35%) | 40.32K Increased by +0.47% | Mar 31, 25 |
| 3 | SATTER MANAGEMENT CO., L.P. | 7.41M (8.99%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 4 | Bvf Inc | 7.00M (8.50%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 5 | Redmile Group, LLC | 6.30M (7.65%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 6 | Point72 Asset Management, L.P. | 5.63M (6.83%) | 299.80K Increased by +5.33% | Dec 31, 24 |
| 7 | Vanguard Group Inc | 5.38M (6.53%) | -167.26K Decreased by -3.11% | Mar 31, 25 |
| 8 | Bain Capital Life Sciences Investors, LLC | 5.25M (6.37%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 9 | Bellevue Group AG | 5.16M (6.26%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 10 | Logos Global Management LP | 4.00M (4.86%) | 1.45M Increased by +36.25% | Mar 31, 25 |
| 11 | Ameriprise Financial Inc | 3.99M (4.84%) | 3.06M Increased by +76.75% | Mar 31, 25 |
| 12 | Sio Capital Management, LLC | 3.40M (4.12%) | 1.03M Increased by +30.34% | Mar 31, 25 |
| 13 | Adage Capital Partners Gp LLC | 2.84M (3.45%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 14 | Nuveen Asset Management, LLC | 2.72M (3.30%) | 164.91K Increased by +6.06% | Dec 31, 24 |
| 15 | Polygon Management Ltd | 2.65M (3.22%) | 1.25M Increased by +47.17% | Mar 31, 25 |
| 16 | Candriam Luxembourg S.C.A. | 2.53M (3.08%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 17 | Geode Capital Management, LLC | 2.25M (2.73%) | 73.53K Increased by +3.28% | Mar 31, 25 |
| 18 | Woodline Partners LP | 2.11M (2.57%) | -576.09K Decreased by -27.24% | Mar 31, 25 |
| 19 | Octagon Capital Advisors LP | 2.05M (2.49%) | 0.00 Increased by 0.00% | Mar 31, 24 |
| 20 | State Street Corp | 2.04M (2.48%) | -2.47M Decreased by -121.13% | Mar 31, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | BB Biotech AG Ord | 5.16M (6.26%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 2 | Fidelity Growth Compy Commingled Pl S | 3.58M (4.35%) | -559.90K Decreased by -15.63% | Apr 30, 25 |
| 3 | Vanguard Total Stock Mkt Idx Inv | 3.01M (3.65%) | 0.00 Increased by 0.00% | May 31, 25 |
| 4 | Vanguard US Total Market Shares ETF | 2.83M (3.44%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 5 | Fidelity Growth Company Fund | 2.59M (3.14%) | -391.70K Decreased by -15.12% | Apr 30, 25 |
| 6 | Candriam Eqs L Biotech C USD Cap | 2.53M (3.08%) | 0.00 Increased by 0.00% | Apr 30, 25 |
| 7 | iShares Russell 2000 ETF | 2.45M (2.97%) | 0.00 Increased by 0.00% | May 31, 25 |
| 8 | Fidelity Growth Compy Commingled Pl O | 2.37M (2.88%) | 0.00 Increased by 0.00% | Aug 31, 24 |
| 9 | SPDR® S&P Biotech ETF | 2.32M (2.82%) | -14.13K Decreased by -0.61% | Feb 28, 25 |
| 10 | Vanguard Institutional Extnd Mkt Idx Tr | 1.38M (1.68%) | 0.00 Increased by 0.00% | May 31, 25 |
| 11 | Fidelity Small Cap Growth | 1.33M (1.62%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 12 | Columbia Small Cap Value I A | 1.32M (1.60%) | 1.32M Increased by +100.00% | May 31, 25 |
| 13 | CT (Lux) American Smaller Com 9U USD | 1.28M (1.56%) | -563.41K Decreased by -43.92% | Mar 31, 25 |
| 14 | CREF Stock R1 | 1.23M (1.49%) | 148.81K Increased by +12.12% | Nov 30, 24 |
| 15 | Fidelity Select Health Care | 1.20M (1.46%) | 0.00 Increased by 0.00% | Apr 30, 25 |
| 16 | Eventide Healthcare & Life Sciences I | 1.02M (1.24%) | 1.02M Increased by +100.00% | Dec 31, 24 |
| 17 | Polar Capital Biotech S Inc | 1.00M (1.21%) | 0.00 Increased by 0.00% | Mar 31, 24 |
| 18 | Fidelity Small Cap Index | 976.92K (1.19%) | 4.15K Increased by +0.42% | Mar 31, 25 |
| 19 | Rhenman Healthcare Equity L/S RC2 SEK | 882.62K (1.07%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 20 | iShares Russell 2000 Value ETF | 882.34K (1.07%) | 0.00 Increased by 0.00% | May 31, 25 |