| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | FMR Inc | 15.70M (14.11%) | 2.43M Increased by +15.50% | Jun 30, 25 |
| 2 | BlackRock Inc | 7.96M (7.16%) | -564.14K Decreased by -7.09% | Jun 30, 25 |
| 3 | SATTER MANAGEMENT CO., L.P. | 7.41M (6.66%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 4 | Bvf Inc | 7.00M (6.29%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 5 | Redmile Group, LLC | 6.30M (5.66%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 6 | Point72 Asset Management, L.P. | 5.63M (5.06%) | 299.80K Increased by +5.33% | Dec 31, 24 |
| 7 | Vanguard Group Inc | 5.37M (4.82%) | -13.62K Decreased by -0.25% | Jun 30, 25 |
| 8 | Bain Capital Life Sciences Investors, LLC | 5.25M (4.72%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 9 | Bellevue Group AG | 5.16M (4.64%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 10 | Sio Capital Management, LLC | 4.10M (3.68%) | 697.98K Increased by +17.04% | Jun 30, 25 |
| 11 | Adage Capital Partners Gp LLC | 2.84M (2.55%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 12 | Polygon Management Ltd | 2.81M (2.53%) | 160.00K Increased by +5.69% | Jun 30, 25 |
| 13 | Nuveen Asset Management, LLC | 2.72M (2.45%) | 164.91K Increased by +6.06% | Dec 31, 24 |
| 14 | Candriam Luxembourg S.C.A. | 2.53M (2.28%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 15 | Millennium Management LLC | 2.51M (2.26%) | 2.34M Increased by +93.03% | Jun 30, 25 |
| 16 | Logos Global Management LP | 2.41M (2.17%) | -1.59M Decreased by -65.98% | Jun 30, 25 |
| 17 | Geode Capital Management, LLC | 2.28M (2.05%) | 39.76K Increased by +1.74% | Jun 30, 25 |
| 18 | Ameriprise Financial Inc | 2.17M (1.95%) | -1.82M Decreased by -83.98% | Jun 30, 25 |
| 19 | Octagon Capital Advisors LP | 2.05M (1.84%) | 0.00 Increased by 0.00% | Mar 31, 24 |
| 20 | Morgan Stanley - Brokerage Accounts | 2.02M (1.81%) | 217.80K Increased by +10.80% | Jun 30, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | BB Biotech AG Ord | 5.16M (4.64%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 2 | FIAM Small Cap Core CIT Cl B | 3.45M (3.10%) | 2.46M Increased by +71.18% | Jun 30, 25 |
| 3 | Vanguard Total Stock Mkt Idx Inv | 3.11M (2.79%) | 99.45K Increased by +3.20% | Jul 31, 25 |
| 4 | Vanguard US Total Market Shares ETF | 2.83M (2.54%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 5 | Candriam Eqs L Biotech C USD Cap | 2.53M (2.28%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 6 | Fidelity Growth Compy Commingled Pl O | 2.37M (2.13%) | 0.00 Increased by 0.00% | Aug 31, 24 |
| 7 | SPDR® S&P Biotech ETF | 2.32M (2.08%) | -14.13K Decreased by -0.61% | Feb 28, 25 |
| 8 | iShares Russell 2000 ETF | 2.31M (2.07%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 9 | Fidelity Growth Compy Commingled Pl S | 1.85M (1.66%) | -604.61K Decreased by -32.68% | Jul 31, 25 |
| 10 | Columbia Small Cap Value Discv A | 1.36M (1.22%) | 37.30K Increased by +2.75% | Jul 31, 25 |
| 11 | Columbia Small Cap Value I A | 1.36M (1.22%) | 37.30K Increased by +2.75% | Jul 31, 25 |
| 12 | Fidelity Small Cap Growth | 1.33M (1.20%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 13 | Columbia Small Cap Value Discovery Fund | 1.32M (1.19%) | 491.95K Increased by +37.26% | Jun 30, 25 |
| 14 | Columbia Small Cap Value I | 1.32M (1.19%) | 491.95K Increased by +37.26% | Jun 30, 25 |
| 15 | Fidelity Growth Company Fund | 1.30M (1.17%) | -458.46K Decreased by -35.25% | Jul 31, 25 |
| 16 | CT (Lux) American Smaller Com 9U USD | 1.28M (1.15%) | -563.41K Decreased by -43.92% | Mar 31, 25 |
| 17 | CREF Stock R1 | 1.23M (1.10%) | 148.81K Increased by +12.12% | Nov 30, 24 |
| 18 | Fidelity Select Health Care | 1.20M (1.08%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 19 | Fidelity Series Small Cap Core | 1.12M (1.01%) | 1.11M Increased by +98.89% | Jun 30, 25 |
| 20 | Strategic Advisers Fidelity US TtlStk | 1.10M (0.99%) | 105.30K Increased by +9.60% | Jul 31, 25 |