| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | FMR Inc | 15.70M (17.62%) | 2.43M Increased by +15.50% | Jun 30, 25 |
| 2 | BlackRock Inc | 8.53M (9.57%) | 40.32K Increased by +0.47% | Mar 31, 25 |
| 3 | SATTER MANAGEMENT CO., L.P. | 7.41M (8.32%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 4 | Bvf Inc | 7.00M (7.86%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 5 | Redmile Group, LLC | 6.30M (7.07%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 6 | Point72 Asset Management, L.P. | 5.63M (6.32%) | 299.80K Increased by +5.33% | Dec 31, 24 |
| 7 | Vanguard Group Inc | 5.37M (6.03%) | -13.62K Decreased by -0.25% | Jun 30, 25 |
| 8 | Bain Capital Life Sciences Investors, LLC | 5.25M (5.89%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 9 | Bellevue Group AG | 5.16M (5.79%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 10 | Sio Capital Management, LLC | 4.10M (4.60%) | 697.98K Increased by +17.04% | Jun 30, 25 |
| 11 | Adage Capital Partners Gp LLC | 2.84M (3.19%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 12 | Polygon Management Ltd | 2.81M (3.16%) | 160.00K Increased by +5.69% | Jun 30, 25 |
| 13 | Nuveen Asset Management, LLC | 2.72M (3.05%) | 164.91K Increased by +6.06% | Dec 31, 24 |
| 14 | Candriam Luxembourg S.C.A. | 2.53M (2.85%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 15 | Logos Global Management LP | 2.41M (2.71%) | -1.59M Decreased by -65.98% | Jun 30, 25 |
| 16 | Geode Capital Management, LLC | 2.25M (2.52%) | 73.53K Increased by +3.28% | Mar 31, 25 |
| 17 | Ameriprise Financial Inc | 2.17M (2.43%) | -1.82M Decreased by -83.98% | Jun 30, 25 |
| 18 | Octagon Capital Advisors LP | 2.05M (2.30%) | 0.00 Increased by 0.00% | Mar 31, 24 |
| 19 | State Street Corp | 2.04M (2.29%) | -2.47M Decreased by -121.13% | Mar 31, 25 |
| 20 | Morgan Stanley - Brokerage Accounts | 2.02M (2.26%) | 217.80K Increased by +10.80% | Jun 30, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | BB Biotech AG Ord | 5.16M (5.79%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 2 | FIAM Small Cap Core CIT Cl B | 3.45M (3.88%) | 2.46M Increased by +71.18% | Jun 30, 25 |
| 3 | Vanguard Total Stock Mkt Idx Inv | 3.11M (3.49%) | 99.45K Increased by +3.20% | Jul 31, 25 |
| 4 | Vanguard US Total Market Shares ETF | 2.83M (3.18%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 5 | Candriam Eqs L Biotech C USD Cap | 2.53M (2.85%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 6 | Fidelity Growth Compy Commingled Pl O | 2.37M (2.66%) | 0.00 Increased by 0.00% | Aug 31, 24 |
| 7 | SPDR® S&P Biotech ETF | 2.32M (2.60%) | -14.13K Decreased by -0.61% | Feb 28, 25 |
| 8 | iShares Russell 2000 ETF | 2.31M (2.59%) | -25.77K Decreased by -1.12% | Aug 29, 25 |
| 9 | Fidelity Growth Compy Commingled Pl S | 1.85M (2.08%) | -604.61K Decreased by -32.68% | Jul 31, 25 |
| 10 | Columbia Small Cap Value Discv A | 1.36M (1.52%) | 37.30K Increased by +2.75% | Jul 31, 25 |
| 11 | Columbia Small Cap Value I A | 1.36M (1.52%) | 37.30K Increased by +2.75% | Jul 31, 25 |
| 12 | Fidelity Small Cap Growth | 1.33M (1.50%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 13 | Columbia Small Cap Value Discovery Fund | 1.32M (1.48%) | 491.95K Increased by +37.26% | Jun 30, 25 |
| 14 | Columbia Small Cap Value I | 1.32M (1.48%) | 491.95K Increased by +37.26% | Jun 30, 25 |
| 15 | Fidelity Growth Company Fund | 1.30M (1.46%) | -458.46K Decreased by -35.25% | Jul 31, 25 |
| 16 | CT (Lux) American Smaller Com 9U USD | 1.28M (1.44%) | -563.41K Decreased by -43.92% | Mar 31, 25 |
| 17 | CREF Stock R1 | 1.23M (1.38%) | 148.81K Increased by +12.12% | Nov 30, 24 |
| 18 | Fidelity Select Health Care | 1.20M (1.35%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 19 | Fidelity Series Small Cap Core | 1.12M (1.26%) | 1.11M Increased by +98.89% | Jun 30, 25 |
| 20 | Strategic Advisers Fidelity US TtlStk | 1.10M (1.23%) | 105.30K Increased by +9.60% | Jul 31, 25 |