| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Darwin Global Management, Ltd. | 16.69M (76.13%) | 0 Increased by 0% | Sep 30, 23 |
| 2 | Cormorant Asset Management, LLC | 9.92M (45.27%) | 307.53K Increased by +3.1% | Sep 30, 23 |
| 3 | D. E. Shaw & Co LP | 4M (18.27%) | -11.39K Decreased by -0.28% | Sep 30, 23 |
| 4 | COMMODORE CAPITAL LP | 3.52M (16.05%) | 343.56K Increased by +9.76% | Sep 30, 23 |
| 5 | Paradigm Biocapital Advisors LP | 3.49M (15.91%) | 1.84M Increased by +52.69% | Sep 30, 23 |
| 6 | Federated Hermes Inc | 2.4M (10.93%) | 2.4M Increased by +100% | Sep 30, 23 |
| 7 | VR Adviser, LLC | 2.07M (9.44%) | -414.96K Decreased by -20.05% | Sep 30, 23 |
| 8 | FMR Inc | 1.76M (8.03%) | -449.56K Decreased by -25.53% | Sep 30, 23 |
| 9 | T. Rowe Price Associates, Inc. | 821.56K (3.75%) | -107.75K Decreased by -13.12% | Sep 30, 23 |
| 10 | Citadel Advisors Llc | 768.83K (3.51%) | 41.8K Increased by +5.44% | Sep 30, 23 |
| 11 | Ghost Tree Capital, LLC | 525K (2.39%) | 286.77K Increased by +54.62% | Sep 30, 23 |
| 12 | ExodusPoint Capital Management, LP | 493.39K (2.25%) | 15.84K Increased by +3.21% | Sep 30, 23 |
| 13 | Holocene Advisors, LP | 486.56K (2.22%) | -427.19K Decreased by -87.8% | Sep 30, 23 |
| 14 | Millennium Management LLC | 464.63K (2.12%) | 178.92K Increased by +38.51% | Sep 30, 23 |
| 15 | Ally Bridge Group (NY) LLC | 281.09K (1.28%) | 281.09K Increased by +100% | Sep 30, 23 |
| 16 | Macquarie Group Ltd | 250K (1.14%) | 250K Increased by +100% | Sep 30, 23 |
| 17 | HighVista Strategies LLC | 193.7K (0.88%) | 40.27K Increased by +20.79% | Sep 30, 23 |
| 18 | NWI Management LP | 160.94K (0.73%) | 160.94K Increased by +100% | Sep 30, 23 |
| 19 | Parkman Healthcare Partners LLC | 150K (0.68%) | 150K Increased by +100% | Sep 30, 23 |
| 20 | First Manhattan Co. LLC | 135K (0.62%) | 0 Increased by 0% | Sep 30, 23 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Federated Hermes Kaufmann Growth | 1.28M (5.85%) | 1.28M Increased by +100% | Sep 30, 23 |
| 2 | Federated Hermes Kaufmann R | 1.28M (5.85%) | 1.28M Increased by +100% | Sep 30, 23 |
| 3 | Federated Hermes Kaufmann Small Cap A | 1.08M (4.93%) | 1.08M Increased by +100% | Sep 30, 23 |
| 4 | Federated Hermes Kaufmann Small Cap Grow | 1.08M (4.93%) | 1.08M Increased by +100% | Sep 30, 23 |
| 5 | HBM Healthcare Investments AG Ord | 833.44K (3.8%) | 833.44K Increased by +100% | Sep 30, 23 |
| 6 | TD Health Sciences - I | 63.73K (0.29%) | 0 Increased by 0% | Jun 30, 23 |
| 7 | HBM Global Biotechnology A Cap USD | 50K (0.23%) | 30K Increased by +60% | Sep 30, 23 |
| 8 | Federated Hermes Kaufmann II P | 33.16K (0.15%) | 33.16K Increased by +100% | Sep 30, 23 |
| 9 | HBM Global Healthcare A Cap USD | 30K (0.14%) | 30K Increased by +100% | Sep 30, 23 |
| 10 | T. Rowe Price Hlth Sci Eq Q | 19.27K (0.09%) | 0 Increased by 0% | Sep 30, 23 |
| 11 | Victory Extended Market Index | 6.54K (0.03%) | 855 Increased by +13.07% | Sep 30, 23 |
| 12 | ProFund VP Emerging Markets | 545 (0%) | 545 Increased by +100% | Sep 30, 23 |
| 13 | Rydex Emerging Markets 2X Strategy A | 39 (0%) | 39 Increased by +100% | Sep 30, 23 |