| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | FMR Inc | 30.03M (20.17%) | -1.23M Decreased by -4.10% | Sep 30, 24 |
| 2 | TPG GP A, LLC | 18.72M (12.57%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 3 | BlackRock Inc | 17.77M (11.94%) | 1.33M Increased by +7.47% | Sep 30, 24 |
| 4 | State Street Corporation | 9.18M (6.17%) | 6.76M Increased by +73.57% | Mar 31, 24 |
| 5 | Vanguard Group Inc | 8.33M (5.60%) | 132.03K Increased by +1.59% | Sep 30, 24 |
| 6 | State Street Corp | 7.01M (4.71%) | -655.04K Decreased by -9.34% | Sep 30, 24 |
| 7 | Capital World Investors | 6.90M (4.63%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 8 | PRIMECAP Management Company | 5.67M (3.81%) | -1.97K Decreased by -0.03% | Sep 30, 24 |
| 9 | Citadel Advisors Llc | 5.04M (3.39%) | 2.59M Increased by +51.45% | Sep 30, 24 |
| 10 | T. Rowe Price Associates, Inc. | 4.84M (3.25%) | -951.80K Decreased by -19.67% | Sep 30, 24 |
| 11 | EcoR1 Capital, LLC | 4.49M (3.02%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 12 | Woodline Partners LP | 4.36M (2.93%) | 5.31K Increased by +0.12% | Sep 30, 24 |
| 13 | JPMorgan Chase & Co | 4.09M (2.75%) | -37.35K Decreased by -0.91% | Sep 30, 24 |
| 14 | Boxer Capital LLC | 3.85M (2.59%) | 0.00 Increased by 0.00% | Jun 30, 24 |
| 15 | Geode Capital Management, LLC | 3.23M (2.17%) | 407.07K Increased by +12.61% | Sep 30, 24 |
| 16 | Wildcat Capital Management, LLC | 2.92M (1.96%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 17 | Two Sigma Investments LLC | 2.80M (1.88%) | -162.70K Decreased by -5.82% | Sep 30, 24 |
| 18 | Dimensional Fund Advisors, Inc. | 2.73M (1.83%) | 179.84K Increased by +6.59% | Sep 30, 24 |
| 19 | Perceptive Advisors LLC | 2.73M (1.83%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 20 | Two Sigma Advisers, LLC | 2.41M (1.62%) | 167.90K Increased by +6.97% | Sep 30, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | American Funds SMALLCAP World A | 6.90M (4.63%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 2 | Fidelity Growth Compy Commingled Pl S | 4.66M (3.13%) | 8.35K Increased by +0.18% | Nov 30, 24 |
| 3 | Fidelity Growth Compy Commingled Pl O | 4.58M (3.08%) | 0.00 Increased by 0.00% | Aug 31, 24 |
| 4 | Fidelity Select Health Care | 4.35M (2.92%) | 0.00 Increased by 0.00% | Nov 30, 24 |
| 5 | Vanguard Total Stock Mkt Idx Inv | 4.28M (2.87%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 6 | SPDR® S&P Biotech ETF | 4.16M (2.80%) | -74.10K Decreased by -1.78% | Dec 31, 24 |
| 7 | Vanguard Capital Opportunity Inv | 3.57M (2.40%) | 18.60K Increased by +0.52% | Sep 30, 24 |
| 8 | Fidelity Series Small Cap Opps | 3.54M (2.38%) | -141.30K Decreased by -3.99% | Sep 30, 24 |
| 9 | iShares Russell 2000 ETF | 3.47M (2.33%) | -13.32K Decreased by -0.38% | Dec 31, 24 |
| 10 | T. Rowe Price Health Sciences | 3.17M (2.13%) | -105.97K Decreased by -3.34% | Dec 31, 24 |
| 11 | Fidelity Advisor Health Care I | 3.00M (2.02%) | 0.00 Increased by 0.00% | Nov 30, 24 |
| 12 | Fidelity Advisor® Health Care I | 2.88M (1.94%) | 4.50K Increased by +0.16% | Nov 30, 23 |
| 13 | BGF World Healthscience A2 | 2.47M (1.66%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 14 | Fidelity Growth Company Fund | 2.40M (1.61%) | -5.86K Decreased by -0.24% | Nov 30, 24 |
| 15 | Fidelity Select Biotechnology | 2.36M (1.59%) | 393.60K Increased by +16.68% | Nov 30, 24 |
| 16 | Fidelity® Select Biotechnology | 2.28M (1.53%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 17 | Vanguard Institutional Extnd Mkt Idx Tr | 2.16M (1.45%) | -320.14K Decreased by -14.83% | Dec 31, 24 |
| 18 | Fidelity Stock Selector Small Cap | 2.13M (1.43%) | 143.60K Increased by +6.73% | Sep 30, 24 |
| 19 | Fidelity Advisor Biotechnology I | 2.07M (1.39%) | 0.00 Increased by 0.00% | Nov 30, 24 |
| 20 | Fidelity® Growth Company | 2.07M (1.39%) | 20.58K Increased by +0.99% | Nov 30, 23 |