| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | FMR Inc | 23.77M (15.21%) | -6.25M Decreased by -26.31% | Dec 31, 24 |
| 2 | Pfizer Inc | 22.03M (14.10%) | 22.03M Increased by +100.00% | Dec 31, 24 |
| 3 | TPG GP A, LLC | 18.72M (11.98%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 4 | BlackRock Inc | 18.06M (11.56%) | 289.91K Increased by +1.61% | Dec 31, 24 |
| 5 | State Street Corporation | 9.18M (5.88%) | 6.76M Increased by +73.57% | Mar 31, 24 |
| 6 | Vanguard Group Inc | 8.00M (5.12%) | -327.01K Decreased by -4.09% | Dec 31, 24 |
| 7 | State Street Corp | 7.25M (4.64%) | 236.88K Increased by +3.27% | Dec 31, 24 |
| 8 | Capital World Investors | 6.90M (4.41%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 9 | Citadel Advisors Llc | 5.35M (3.42%) | 309.50K Increased by +5.79% | Dec 31, 24 |
| 10 | PRIMECAP Management Company | 4.93M (3.15%) | -740.92K Decreased by -15.04% | Dec 31, 24 |
| 11 | EcoR1 Capital, LLC | 4.49M (2.87%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 12 | T. Rowe Price Associates, Inc. | 4.49M (2.87%) | -353.17K Decreased by -7.87% | Dec 31, 24 |
| 13 | Woodline Partners LP | 4.36M (2.79%) | -4.07K Decreased by -0.09% | Dec 31, 24 |
| 14 | Boxer Capital LLC | 3.85M (2.46%) | 0.00 Increased by 0.00% | Jun 30, 24 |
| 15 | JPMorgan Chase & Co | 3.74M (2.39%) | -4.44M Decreased by -118.81% | Dec 31, 24 |
| 16 | Dimensional Fund Advisors, Inc. | 3.56M (2.28%) | 831.15K Increased by +23.34% | Dec 31, 24 |
| 17 | Foresite Capital Management VI LLC | 3.45M (2.21%) | 3.45M Increased by +100.00% | Dec 31, 24 |
| 18 | Geode Capital Management, LLC | 3.23M (2.07%) | 5.51K Increased by +0.17% | Dec 31, 24 |
| 19 | Wildcat Capital Management, LLC | 2.92M (1.87%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 20 | Perceptive Advisors LLC | 2.73M (1.74%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | American Funds SMALLCAP World A | 6.90M (4.41%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 2 | Fidelity Growth Compy Commingled Pl O | 4.58M (2.93%) | 0.00 Increased by 0.00% | Aug 31, 24 |
| 3 | Vanguard Total Stock Mkt Idx Inv | 4.28M (2.74%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 4 | Fidelity Select Health Care | 4.00M (2.56%) | -350.00K Decreased by -8.75% | Jan 31, 25 |
| 5 | SPDR® S&P Biotech ETF | 3.90M (2.50%) | -23.78K Decreased by -0.61% | Feb 28, 25 |
| 6 | Fidelity Growth Compy Commingled Pl S | 3.77M (2.41%) | -934.42K Decreased by -24.82% | Feb 28, 25 |
| 7 | Fidelity Series Small Cap Opps | 3.54M (2.26%) | -141.30K Decreased by -3.99% | Sep 30, 24 |
| 8 | iShares Russell 2000 ETF | 3.38M (2.16%) | -29.32K Decreased by -0.87% | Mar 31, 25 |
| 9 | T. Rowe Price Health Sciences | 2.98M (1.91%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 10 | Vanguard Capital Opportunity Inv | 2.97M (1.90%) | -596.71K Decreased by -20.10% | Dec 31, 24 |
| 11 | Fidelity Advisor® Health Care I | 2.88M (1.85%) | 4.50K Increased by +0.16% | Nov 30, 23 |
| 12 | Fidelity Advisor Health Care I | 2.50M (1.60%) | -500.00K Decreased by -20.00% | Jan 31, 25 |
| 13 | BGF World Healthscience A2 | 2.47M (1.58%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 14 | Fidelity® Select Biotechnology | 2.28M (1.46%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 15 | Vanguard Institutional Extnd Mkt Idx Tr | 2.21M (1.42%) | 55.25K Increased by +2.50% | Feb 28, 25 |
| 16 | Fidelity Stock Selector Small Cap | 2.13M (1.36%) | 143.60K Increased by +6.73% | Sep 30, 24 |
| 17 | Fidelity Advisor Biotechnology I | 2.07M (1.33%) | 0.00 Increased by 0.00% | Nov 30, 24 |
| 18 | Fidelity® Growth Company | 2.07M (1.33%) | 20.58K Increased by +0.99% | Nov 30, 23 |
| 19 | PRIMECAP Odyssey Aggressive Growth | 1.83M (1.17%) | -141.94K Decreased by -7.76% | Dec 31, 24 |
| 20 | Fidelity Growth Company Fund | 1.69M (1.08%) | -659.80K Decreased by -39.12% | Feb 28, 25 |