| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Pfizer Inc | 22.03M (14.08%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 2 | TPG GP A, LLC | 18.72M (11.96%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 3 | BlackRock Inc | 17.93M (11.46%) | -129.75K Decreased by -0.72% | Mar 31, 25 |
| 4 | Capital World Investors | 12.27M (7.84%) | 5.37M Increased by +43.77% | Mar 31, 25 |
| 5 | Darwin Global Management, Ltd. | 10.45M (6.68%) | 10.45M Increased by +100.00% | Mar 31, 25 |
| 6 | State Street Corporation | 9.18M (5.87%) | 6.76M Increased by +73.57% | Mar 31, 24 |
| 7 | Vanguard Group Inc | 8.07M (5.15%) | 66.86K Increased by +0.83% | Mar 31, 25 |
| 8 | FMR Inc | 7.39M (4.72%) | -16.38M Decreased by -221.50% | Mar 31, 25 |
| 9 | Goldman Sachs Group Inc | 5.85M (3.74%) | 3.75M Increased by +64.01% | Mar 31, 25 |
| 10 | Citadel Advisors Llc | 5.35M (3.42%) | 309.50K Increased by +5.79% | Dec 31, 24 |
| 11 | JPMorgan Chase & Co | 5.14M (3.28%) | 1.40M Increased by +27.27% | Mar 31, 25 |
| 12 | PRIMECAP Management Company | 4.93M (3.15%) | 4.50K Increased by +0.09% | Mar 31, 25 |
| 13 | EcoR1 Capital, LLC | 4.49M (2.87%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 14 | Woodline Partners LP | 4.36M (2.79%) | 376.00 Increased by +0.01% | Mar 31, 25 |
| 15 | T. Rowe Price Associates, Inc. | 4.21M (2.69%) | -279.57K Decreased by -6.65% | Mar 31, 25 |
| 16 | Boxer Capital LLC | 3.85M (2.46%) | 0.00 Increased by 0.00% | Jun 30, 24 |
| 17 | Foresite Capital Management VI LLC | 3.45M (2.20%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 18 | Geode Capital Management, LLC | 3.36M (2.15%) | 126.82K Increased by +3.78% | Mar 31, 25 |
| 19 | Dimensional Fund Advisors, Inc. | 3.18M (2.03%) | -381.77K Decreased by -12.01% | Mar 31, 25 |
| 20 | Wildcat Capital Management, LLC | 2.92M (1.87%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | American Funds SMALLCAP World A | 12.27M (7.84%) | 5.37M Increased by +43.77% | Mar 31, 25 |
| 2 | Fidelity Growth Compy Commingled Pl O | 4.58M (2.93%) | 0.00 Increased by 0.00% | Aug 31, 24 |
| 3 | Vanguard US Total Market Shares ETF | 4.34M (2.77%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 4 | Vanguard Total Stock Mkt Idx Inv | 4.28M (2.73%) | 0.00 Increased by 0.00% | Apr 30, 25 |
| 5 | Fidelity Select Health Care | 4.00M (2.56%) | -350.00K Decreased by -8.75% | Jan 31, 25 |
| 6 | SPDR® S&P Biotech ETF | 3.90M (2.49%) | -23.78K Decreased by -0.61% | Feb 28, 25 |
| 7 | Fidelity Series Small Cap Opps | 3.54M (2.26%) | -141.30K Decreased by -3.99% | Sep 30, 24 |
| 8 | iShares Russell 2000 ETF | 3.15M (2.01%) | 533.00 Increased by +0.02% | Apr 30, 25 |
| 9 | Vanguard Capital Opportunity Inv | 2.96M (1.89%) | -4.80K Decreased by -0.16% | Mar 31, 25 |
| 10 | T. Rowe Price Health Sciences | 2.94M (1.88%) | -44.34K Decreased by -1.51% | Mar 31, 25 |
| 11 | Fidelity Advisor® Health Care I | 2.88M (1.84%) | 4.50K Increased by +0.16% | Nov 30, 23 |
| 12 | Fidelity Advisor Health Care I | 2.50M (1.60%) | -500.00K Decreased by -20.00% | Jan 31, 25 |
| 13 | BGF World Healthscience A2 | 2.47M (1.58%) | 0.00 Increased by 0.00% | Jan 31, 25 |
| 14 | Fidelity Growth Compy Commingled Pl S | 2.46M (1.57%) | -1.31M Decreased by -53.05% | Mar 31, 25 |
| 15 | Vanguard Institutional Extnd Mkt Idx Tr | 2.36M (1.51%) | 807.00 Increased by +0.03% | Apr 30, 25 |
| 16 | Fidelity® Select Biotechnology | 2.28M (1.46%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 17 | Fidelity Stock Selector Small Cap | 2.13M (1.36%) | 143.60K Increased by +6.73% | Sep 30, 24 |
| 18 | Fidelity Advisor Biotechnology I | 2.07M (1.33%) | 0.00 Increased by 0.00% | Nov 30, 24 |
| 19 | Fidelity® Growth Company | 2.07M (1.32%) | 20.58K Increased by +0.99% | Nov 30, 23 |
| 20 | PRIMECAP Odyssey Aggressive Growth | 1.84M (1.17%) | 10.00K Increased by +0.54% | Mar 31, 25 |