| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Pfizer Inc | 22.03M (8.14%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 2 | BlackRock Inc | 19.09M (7.05%) | 1.42M Increased by +7.41% | Mar 31, 26 |
| 3 | TPG GP A, LLC | 18.72M (6.92%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 4 | Capital World Investors | 11.15M (4.12%) | -1.12M Decreased by -10.00% | Jun 30, 25 |
| 5 | Darwin Global Management, Ltd. | 10.48M (3.87%) | 30.00K Increased by +0.29% | Jun 30, 25 |
| 6 | Vanguard Group Inc | 9.25M (3.42%) | 230.84K Increased by +2.50% | Dec 31, 25 |
| 7 | State Street Corporation | 9.18M (3.39%) | 6.76M Increased by +73.57% | Mar 31, 24 |
| 8 | State Street Corp | 8.66M (3.20%) | 5.90M Increased by +68.11% | Mar 31, 26 |
| 9 | PRIMECAP Management Company | 8.38M (3.10%) | 240.00K Increased by +2.86% | Mar 31, 26 |
| 10 | FMR Inc | 7.39M (2.73%) | -16.38M Decreased by -221.50% | Mar 31, 25 |
| 11 | Vanguard Capital Management, LLC | 6.92M (2.56%) | 6.92M Increased by +100.00% | Mar 31, 26 |
| 12 | Citadel Advisors Llc | 6.79M (2.51%) | -5.32M Decreased by -78.28% | Mar 31, 26 |
| 13 | Goldman Sachs Group Inc | 5.50M (2.03%) | -350.83K Decreased by -6.38% | Jun 30, 25 |
| 14 | T. Rowe Price Associates, Inc. | 5.38M (1.99%) | 2.17M Increased by +40.36% | Mar 31, 26 |
| 15 | Two Sigma Investments LLC | 5.38M (1.99%) | 1.95M Increased by +36.31% | Mar 31, 26 |
| 16 | JPMorgan Chase & Co | 5.14M (1.90%) | 1.40M Increased by +27.27% | Mar 31, 25 |
| 17 | EcoR1 Capital, LLC | 4.49M (1.66%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 18 | Geode Capital Management, LLC | 4.12M (1.52%) | 191.27K Increased by +4.64% | Mar 31, 26 |
| 19 | Boxer Capital LLC | 3.85M (1.42%) | 0.00 Increased by 0.00% | Jun 30, 24 |
| 20 | Frazier Life Sciences Management, L.P. | 3.80M (1.40%) | -72.08K Decreased by -1.90% | Mar 31, 26 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | American Funds SMALLCAP World A | 11.15M (4.12%) | -1.12M Decreased by -10.00% | Jun 30, 25 |
| 2 | Fidelity Select Biotechnology | 8.83M (3.26%) | 7.43M Increased by +84.13% | Apr 30, 26 |
| 3 | Vanguard Total Stock Mkt Idx Inv | 8.43M (3.11%) | 3.55M Increased by +42.11% | Apr 30, 26 |
| 4 | State Street® SPDR® S&P® Biotech ETF | 5.81M (2.15%) | -36.13K Decreased by -0.62% | May 31, 26 |
| 5 | Vanguard Capital Opportunity Inv | 5.36M (1.98%) | 175.00K Increased by +3.26% | Mar 31, 26 |
| 6 | Fidelity Growth Compy Commingled Pl O | 4.58M (1.69%) | 0.00 Increased by 0.00% | Aug 31, 24 |
| 7 | Vanguard US Total Market Shares ETF | 4.34M (1.60%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 8 | Fidelity Select Health Care | 4.00M (1.48%) | -350.00K Decreased by -8.75% | Jan 31, 25 |
| 9 | SPDR® S&P Biotech ETF | 3.90M (1.44%) | -23.78K Decreased by -0.61% | Feb 28, 25 |
| 10 | iShares Russell 2000 ETF | 3.72M (1.37%) | 34.37K Increased by +0.92% | May 29, 26 |
| 11 | Fidelity Series Small Cap Opps | 3.54M (1.31%) | -141.30K Decreased by -3.99% | Sep 30, 24 |
| 12 | T. Rowe Price Health Sciences | 3.44M (1.27%) | -386.90K Decreased by -11.23% | Apr 30, 26 |
| 13 | Fidelity Advisor® Health Care I | 2.88M (1.07%) | 4.50K Increased by +0.16% | Nov 30, 23 |
| 14 | Vanguard Institutional Extnd Mkt Idx Tr | 2.84M (1.05%) | 960.65K Increased by +33.78% | Apr 30, 26 |
| 15 | PRIMECAP Odyssey Aggressive Growth | 2.78M (1.03%) | 50.00K Increased by +1.80% | Mar 31, 26 |
| 16 | Fidelity Advisor Health Care I | 2.50M (0.92%) | -500.00K Decreased by -20.00% | Jan 31, 25 |
| 17 | BGF World Healthscience A2 USD | 2.47M (0.91%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 18 | Fidelity Growth Compy Commingled Pl S | 2.46M (0.91%) | -1.31M Decreased by -53.05% | Mar 31, 25 |
| 19 | BGF World Healthscience A2 | 2.44M (0.90%) | 0.00 Increased by 0.00% | Feb 28, 26 |
| 20 | abrdn Life Sciences Investors | 2.40M (0.89%) | 270.40K Increased by +11.27% | May 31, 26 |