| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Pfizer Inc | 22.03M (13.35%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 2 | TPG GP A, LLC | 18.72M (11.34%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 3 | BlackRock Inc | 17.93M (10.87%) | -129.75K Decreased by -0.72% | Mar 31, 25 |
| 4 | Capital World Investors | 11.15M (6.76%) | -1.12M Decreased by -10.00% | Jun 30, 25 |
| 5 | Darwin Global Management, Ltd. | 10.45M (6.33%) | 10.45M Increased by +100.00% | Mar 31, 25 |
| 6 | Citadel Advisors Llc | 10.20M (6.18%) | 4.85M Increased by +47.57% | Mar 31, 25 |
| 7 | State Street Corporation | 9.18M (5.57%) | 6.76M Increased by +73.57% | Mar 31, 24 |
| 8 | Vanguard Group Inc | 8.26M (5.01%) | 191.57K Increased by +2.32% | Jun 30, 25 |
| 9 | FMR Inc | 7.39M (4.48%) | -16.38M Decreased by -221.50% | Mar 31, 25 |
| 10 | PRIMECAP Management Company | 5.72M (3.47%) | 787.30K Increased by +13.77% | Jun 30, 25 |
| 11 | Goldman Sachs Group Inc | 5.50M (3.34%) | -350.83K Decreased by -6.38% | Jun 30, 25 |
| 12 | JPMorgan Chase & Co | 5.14M (3.11%) | 1.40M Increased by +27.27% | Mar 31, 25 |
| 13 | EcoR1 Capital, LLC | 4.49M (2.72%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 14 | Woodline Partners LP | 4.36M (2.64%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 15 | T. Rowe Price Associates, Inc. | 4.03M (2.44%) | -175.13K Decreased by -4.34% | Jun 30, 25 |
| 16 | Boxer Capital LLC | 3.85M (2.33%) | 0.00 Increased by 0.00% | Jun 30, 24 |
| 17 | Geode Capital Management, LLC | 3.36M (2.04%) | 126.82K Increased by +3.78% | Mar 31, 25 |
| 18 | Wildcat Capital Management, LLC | 2.92M (1.77%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 19 | Foresite Capital Management VI LLC | 2.88M (1.74%) | -572.92K Decreased by -19.93% | Jun 30, 25 |
| 20 | State Street Corp | 2.79M (1.69%) | -4.46M Decreased by -159.88% | Mar 31, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | American Funds SMALLCAP World A | 11.15M (6.76%) | -1.12M Decreased by -10.00% | Jun 30, 25 |
| 2 | Fidelity Growth Compy Commingled Pl O | 4.58M (2.78%) | 0.00 Increased by 0.00% | Aug 31, 24 |
| 3 | Vanguard US Total Market Shares ETF | 4.34M (2.63%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 4 | Vanguard Total Stock Mkt Idx Inv | 4.19M (2.54%) | -92.41K Decreased by -2.21% | Jul 31, 25 |
| 5 | Fidelity Select Health Care | 4.00M (2.42%) | -350.00K Decreased by -8.75% | Jan 31, 25 |
| 6 | SPDR® S&P Biotech ETF | 3.90M (2.37%) | -23.78K Decreased by -0.61% | Feb 28, 25 |
| 7 | Vanguard Capital Opportunity Inv | 3.56M (2.16%) | 600.00K Increased by +16.83% | Jun 30, 25 |
| 8 | Fidelity Series Small Cap Opps | 3.54M (2.15%) | -141.30K Decreased by -3.99% | Sep 30, 24 |
| 9 | iShares Russell 2000 ETF | 3.50M (2.12%) | -66.57K Decreased by -1.90% | Jul 31, 25 |
| 10 | Fidelity Advisor® Health Care I | 2.88M (1.75%) | 4.50K Increased by +0.16% | Nov 30, 23 |
| 11 | T. Rowe Price Health Sciences | 2.75M (1.67%) | -103.60K Decreased by -3.77% | Jun 30, 25 |
| 12 | Fidelity Advisor Health Care I | 2.50M (1.52%) | -500.00K Decreased by -20.00% | Jan 31, 25 |
| 13 | BGF World Healthscience A2 | 2.47M (1.50%) | 0.00 Increased by 0.00% | Apr 30, 25 |
| 14 | BGF World Healthscience A2 USD | 2.47M (1.50%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 15 | Fidelity Growth Compy Commingled Pl S | 2.46M (1.49%) | -1.31M Decreased by -53.05% | Mar 31, 25 |
| 16 | Fidelity® Select Biotechnology | 2.28M (1.38%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 17 | Fidelity Stock Selector Small Cap | 2.13M (1.29%) | 143.60K Increased by +6.73% | Sep 30, 24 |
| 18 | Fidelity Advisor Biotechnology I | 2.07M (1.26%) | 0.00 Increased by 0.00% | Nov 30, 24 |
| 19 | Fidelity® Growth Company | 2.07M (1.26%) | 20.58K Increased by +0.99% | Nov 30, 23 |
| 20 | PRIMECAP Odyssey Aggressive Growth | 2.03M (1.23%) | 187.30K Increased by +9.25% | Jun 30, 25 |