| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Bvf Inc | 8.55M (14.72%) | -100K Decreased by -1.17% | Sep 30, 23 |
| 2 | T. Rowe Price Associates, Inc. | 7.92M (13.63%) | 1.58M Increased by +19.93% | Dec 31, 23 |
| 3 | NEA Management Company, LLC | 6.15M (10.58%) | 0 Increased by 0% | Dec 31, 23 |
| 4 | BlackRock Inc | 5.74M (9.87%) | -244.36K Decreased by -4.26% | Sep 30, 23 |
| 5 | RiverVest Venture Management LLC | 4.99M (8.58%) | 99.59K Increased by +2% | Sep 30, 23 |
| 6 | Logos Global Management LP | 4.65M (8%) | -600K Decreased by -12.9% | Sep 30, 23 |
| 7 | Citadel Advisors Llc | 4.15M (7.14%) | 1.22M Increased by +29.32% | Sep 30, 23 |
| 8 | Redmile Group, LLC | 4.14M (7.12%) | 1.85M Increased by +44.77% | Sep 30, 23 |
| 9 | Blackstone Inc | 4.1M (7.05%) | 2.09M Increased by +51.03% | Sep 30, 23 |
| 10 | Vanguard Group Inc | 3.27M (5.62%) | 16.97K Increased by +0.52% | Sep 30, 23 |
| 11 | Vivo Capital, LLC | 2.99M (5.14%) | 0 Increased by 0% | Sep 30, 23 |
| 12 | Deep Track Capital, LP | 2.51M (4.32%) | 2.51M Increased by +100% | Dec 31, 23 |
| 13 | Geode Capital Management, LLC | 1.49M (2.57%) | 72.13K Increased by +4.83% | Sep 30, 23 |
| 14 | State Street Corporation | 1.46M (2.51%) | -2.92M Decreased by -200.26% | Sep 30, 23 |
| 15 | Ikarian Capital, LLC | 787.06K (1.35%) | 14.96K Increased by +1.9% | Sep 30, 23 |
| 16 | Sectoral Asset Management Inc | 770.13K (1.33%) | 335.82K Increased by +43.61% | Sep 30, 23 |
| 17 | Vontobel Holding Ltd. | 752.38K (1.29%) | -17.75K Decreased by -2.36% | Dec 31, 23 |
| 18 | EcoR1 Capital, LLC | 748.9K (1.29%) | 0 Increased by 0% | Sep 30, 23 |
| 19 | Junked Platinum Investment Management Ltd | 635.02K (1.09%) | 0 Increased by 0% | Dec 31, 23 |
| 20 | Morgan Stanley - Brokerage Accounts | 622.33K (1.07%) | 281.01K Increased by +45.15% | Sep 30, 23 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | T. Rowe Price New Horizons | 4.22M (7.27%) | 758.66K Increased by +17.96% | Dec 31, 23 |
| 2 | US Small-Cap Growth II Equity Comp | 4.22M (7.27%) | 758.66K Increased by +17.96% | Dec 31, 23 |
| 3 | Vanguard Total Stock Mkt Idx Inv | 2.34M (4.02%) | 514.9K Increased by +22.04% | Jan 31, 24 |
| 4 | Fidelity Advisor Biotechnology I | 1.92M (3.3%) | 0 Increased by 0% | Jan 31, 24 |
| 5 | iShares Russell 2000 ETF | 1.59M (2.74%) | -261 Decreased by -0.02% | Feb 29, 24 |
| 6 | HBM Healthcare Investments AG Ord | 1.5M (2.58%) | 0 Increased by 0% | Dec 31, 23 |
| 7 | T. Rowe Price Health Sciences | 1.23M (2.12%) | 569.94K Increased by +46.24% | Dec 31, 23 |
| 8 | Vanguard Institutional Extnd Mkt Idx Tr | 1.01M (1.74%) | 0 Increased by 0% | Jan 31, 24 |
| 9 | Fidelity Advisor® Biotechnology I | 989.11K (1.7%) | 989.11K Increased by +100% | Nov 30, 23 |
| 10 | T. Rowe Price New Horizons Tr-Z | 741.93K (1.28%) | 167.94K Increased by +22.64% | Dec 31, 23 |
| 11 | Fidelity Small Cap Index | 666.11K (1.15%) | 10.72K Increased by +1.61% | Dec 31, 23 |
| 12 | iShares Russell 2000 Value ETF | 651.58K (1.12%) | 824 Increased by +0.13% | Feb 1, 24 |
| 13 | Fidelity® Small Cap Index | 636.14K (1.09%) | 15.51K Increased by +2.44% | Oct 31, 23 |
| 14 | State St Russell Sm/Mid Cp® Indx NL Cl C | 503K (0.87%) | 19.4K Increased by +3.86% | Feb 29, 24 |
| 15 | Fidelity® Extended Market Index | 401.52K (0.69%) | 0 Increased by 0% | Nov 30, 23 |
| 16 | Fidelity Extended Market Index | 367.11K (0.63%) | 0 Increased by 0% | Jan 31, 24 |
| 17 | State St Russell Sm Cap® Indx SL Cl I | 245K (0.42%) | 0 Increased by 0% | Feb 29, 24 |
| 18 | Vanguard Russell 2000 ETF | 225.64K (0.39%) | 4.88K Increased by +2.16% | Jan 31, 24 |
| 19 | Fidelity Enhanced Small Cap ETF | 205.39K (0.35%) | -3.56K Decreased by -1.73% | Feb 29, 24 |
| 20 | Fidelity® Small Cap Enhanced Index | 205.39K (0.35%) | -3.56K Decreased by -1.73% | Feb 29, 24 |