| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | FMR Inc | 14.69M (19.98%) | 94.85K Increased by +0.65% | Dec 31, 24 |
| 2 | RA Capital Management, LLC | 9.70M (13.19%) | 9.70M Increased by +100.00% | Dec 31, 24 |
| 3 | BlackRock Inc | 9.14M (12.43%) | -215.30K Decreased by -2.36% | Dec 31, 24 |
| 4 | Vanguard Group Inc | 5.62M (7.64%) | 160.65K Increased by +2.86% | Dec 31, 24 |
| 5 | Deep Track Capital, LP | 4.63M (6.30%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 6 | EcoR1 Capital, LLC | 4.06M (5.52%) | 0.00 Increased by 0.00% | Mar 31, 24 |
| 7 | State Street Corporation | 3.92M (5.32%) | 797.64K Increased by +20.37% | Mar 31, 24 |
| 8 | Merck & Co Inc | 3.55M (4.82%) | 3.55M Increased by +100.00% | Dec 31, 24 |
| 9 | BRAIDWELL LP | 2.16M (2.94%) | -222.46K Decreased by -10.31% | Sep 30, 24 |
| 10 | Geode Capital Management, LLC | 1.91M (2.60%) | 10.31K Increased by +0.54% | Dec 31, 24 |
| 11 | State Street Corp | 1.85M (2.52%) | -767.51K Decreased by -41.50% | Dec 31, 24 |
| 12 | JPMorgan Chase & Co | 1.64M (2.23%) | -3.82M Decreased by -232.26% | Dec 31, 24 |
| 13 | Euclidean Capital LLC | 1.31M (1.78%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 14 | Verition Fund Managegment, LLC | 1.25M (1.70%) | 1.11M Increased by +88.31% | Mar 31, 24 |
| 15 | Soleus Capital Management, L.P. | 1.21M (1.64%) | -1.03M Decreased by -85.44% | Sep 30, 24 |
| 16 | Deutsche Bank AG | 1.11M (1.50%) | -48.05K Decreased by -4.34% | Dec 31, 24 |
| 17 | Deerfield Management Co | 1.07M (1.45%) | 11.77K Increased by +1.10% | Dec 31, 24 |
| 18 | Jacobs Levy Equity Management, Inc. | 1.06M (1.44%) | 42.00K Increased by +3.96% | Dec 31, 24 |
| 19 | 5AM Venture Management, LLC | 995.84K (1.35%) | 995.84K Increased by +100.00% | Dec 31, 24 |
| 20 | Ikarian Capital, LLC | 950.00K (1.29%) | 950.00K Increased by +100.00% | Dec 31, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Fidelity Growth Compy Commingled Pl S | 5.29M (7.20%) | 14.20K Increased by +0.27% | Mar 31, 25 |
| 2 | Fidelity Growth Compy Commingled Pl O | 5.02M (6.83%) | 13.10K Increased by +0.26% | Aug 31, 24 |
| 3 | Fidelity Growth Company Fund | 3.67M (4.99%) | 43.00K Increased by +1.17% | Mar 31, 25 |
| 4 | Fidelity® Select Biotechnology | 3.38M (4.60%) | 3.00K Increased by +0.09% | Nov 30, 23 |
| 5 | Fidelity® Growth Company | 3.10M (4.22%) | 12.30K Increased by +0.40% | Nov 30, 23 |
| 6 | Fidelity Select Biotechnology | 3.01M (4.10%) | -521.50K Decreased by -17.30% | Mar 31, 25 |
| 7 | Vanguard Total Stock Mkt Idx Inv | 2.47M (3.36%) | 43.32K Increased by +1.75% | Mar 31, 25 |
| 8 | Vanguard US Total Market Shares ETF | 2.37M (3.22%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 9 | iShares Russell 2000 ETF | 2.00M (2.71%) | 337.00 Increased by +0.02% | Apr 30, 25 |
| 10 | JPMorgan Small Cap Growth A | 1.51M (2.05%) | 605.20K Increased by +40.17% | Sep 30, 24 |
| 11 | Fidelity Growth Company K6 | 1.30M (1.77%) | 33.59K Increased by +2.59% | Mar 31, 25 |
| 12 | Xtrackers S&P 500 Swap ETF 1C | 1.20M (1.63%) | 1.09M Increased by +90.68% | Jun 30, 24 |
| 13 | Fidelity® Growth Company K6 | 1.17M (1.59%) | -16.86K Decreased by -1.44% | Nov 30, 23 |
| 14 | Vanguard Institutional Extnd Mkt Idx Tr | 1.16M (1.58%) | 14.50K Increased by +1.25% | Mar 31, 25 |
| 15 | Fidelity Series Growth Company | 993.25K (1.35%) | 33.60K Increased by +3.38% | Mar 31, 25 |
| 16 | Fidelity Small Cap Index | 813.88K (1.11%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 17 | Vanguard Small Cap Index | 810.62K (1.10%) | 2.51K Increased by +0.31% | Nov 30, 23 |
| 18 | SPDR® S&P Biotech ETF | 797.27K (1.08%) | -24.21K Decreased by -3.04% | Nov 27, 24 |
| 19 | iShares Russell 2000 Growth ETF | 783.51K (1.07%) | 0.00 Increased by 0.00% | Apr 30, 25 |
| 20 | Fidelity® Series Growth Company | 782.36K (1.06%) | 3.90K Increased by +0.50% | Nov 30, 23 |