| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Wellington Management Company LLP | 7.38M (11.10%) | -519.67K Decreased by -7.04% | Dec 31, 24 |
| 2 | RTW INVESTMENTS, LLC | 6.86M (10.32%) | 940.39K Increased by +13.71% | Dec 31, 24 |
| 3 | HHG PLC | 6.03M (9.08%) | -1.04M Decreased by -17.29% | Dec 31, 24 |
| 4 | BlackRock Inc | 5.92M (8.91%) | 176.39K Increased by +2.98% | Dec 31, 24 |
| 5 | General Atlantic Llc | 5.23M (7.87%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 6 | T. Rowe Price Associates, Inc. | 4.32M (6.50%) | 513.61K Increased by +11.88% | Dec 31, 24 |
| 7 | State Street Corporation | 3.80M (5.71%) | -1.33M Decreased by -34.89% | Mar 31, 24 |
| 8 | Vanguard Group Inc | 3.70M (5.57%) | 27.83K Increased by +0.75% | Dec 31, 24 |
| 9 | FMR Inc | 2.75M (4.14%) | 162.82K Increased by +5.92% | Sep 30, 23 |
| 10 | State Street Corp | 2.34M (3.51%) | -167.00K Decreased by -7.15% | Dec 31, 24 |
| 11 | Adage Capital Partners Gp LLC | 1.94M (2.92%) | -1.11M Decreased by -56.92% | Sep 30, 23 |
| 12 | Morgan Stanley - Brokerage Accounts | 1.89M (2.85%) | 1.09M Increased by +57.33% | Jun 30, 24 |
| 13 | AllianceBernstein L.P. | 1.84M (2.77%) | -177.81K Decreased by -9.67% | Dec 31, 24 |
| 14 | Alkeon Capital Management, LLC | 1.76M (2.65%) | -1.56M Decreased by -88.78% | Dec 31, 24 |
| 15 | Boxer Capital LLC | 1.68M (2.52%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 16 | Geode Capital Management, LLC | 1.56M (2.35%) | -11.38K Decreased by -0.73% | Dec 31, 24 |
| 17 | Deep Track Capital, LP | 1.49M (2.24%) | 800.22K Increased by +53.71% | Dec 31, 24 |
| 18 | Citadel Advisors Llc | 1.35M (2.04%) | 1.20M Increased by +88.94% | Dec 31, 24 |
| 19 | Fred Alger Management, LLC | 1.34M (2.01%) | 1.25M Increased by +93.21% | Mar 31, 24 |
| 20 | T. Rowe Price Investment Management,Inc. | 1.30M (1.96%) | -467.15K Decreased by -35.93% | Sep 30, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Health Care Inv | 3.66M (5.50%) | -743.67K Decreased by -20.33% | Mar 31, 25 |
| 2 | Vanguard Total Stock Mkt Idx Inv | 2.29M (3.45%) | 166.68K Increased by +7.27% | Mar 31, 25 |
| 3 | Vanguard US Total Market Shares ETF | 1.94M (2.92%) | 2.50K Increased by +0.13% | Sep 30, 24 |
| 4 | iShares Russell 2000 ETF | 1.84M (2.76%) | 310.00 Increased by +0.02% | Apr 30, 25 |
| 5 | T. Rowe Price New Horizons | 1.81M (2.72%) | -24.48K Decreased by -1.35% | Mar 31, 25 |
| 6 | US Small-Cap Growth II Equity Comp | 1.81M (2.72%) | 29.50K Increased by +1.63% | Mar 31, 25 |
| 7 | Janus Henderson Global Life Sciences | 1.64M (2.46%) | -378.12K Decreased by -23.12% | Dec 31, 24 |
| 8 | Janus Henderson Global Life Sciences D | 1.56M (2.34%) | -68.31K Decreased by -4.39% | Feb 28, 25 |
| 9 | Janus Selection Global Life Science AUSD | 1.55M (2.33%) | 94.70K Increased by +6.12% | Jun 30, 24 |
| 10 | Janus Global Life Science AUSD | 1.30M (1.96%) | -193.92K Decreased by -14.90% | Dec 31, 24 |
| 11 | Janus Henderson Glb Life Scn I2 USD | 1.26M (1.89%) | -1.16K Decreased by -0.09% | Mar 31, 25 |
| 12 | T. Rowe Price Health Sciences | 1.24M (1.87%) | -18.77K Decreased by -1.51% | Mar 31, 25 |
| 13 | Vanguard Institutional Extnd Mkt Idx Tr | 1.08M (1.62%) | 27.93K Increased by +2.60% | Mar 31, 25 |
| 14 | SPDR® S&P Biotech ETF | 883.03K (1.33%) | -15.48K Decreased by -1.75% | Apr 30, 25 |
| 15 | Janus Henderson US SMID Cap Growth | 758.39K (1.14%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 16 | Fidelity Small Cap Index | 672.41K (1.01%) | 4.33K Increased by +0.64% | Feb 28, 25 |
| 17 | Pictet-Biotech P USD | 630.78K (0.95%) | -2.99K Decreased by -0.47% | Jul 31, 23 |
| 18 | Lord Abbett Developing Growth A | 600.34K (0.90%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 19 | iShares Russell 2000 Value ETF | 583.13K (0.88%) | -1.98K Decreased by -0.34% | Apr 30, 25 |
| 20 | AB Small Cap Growth A | 532.20K (0.80%) | -12.02K Decreased by -2.26% | Dec 31, 24 |