| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | BlackRock Inc | 18.80M (7.17%) | 423.10K Increased by +2.25% | Sep 30, 25 |
| 2 | Vanguard Group Inc | 16.02M (6.11%) | 468.94K Increased by +2.93% | Dec 31, 25 |
| 3 | State Street Corp | 11.84M (4.52%) | 3.85M Increased by +32.48% | Sep 30, 25 |
| 4 | Geode Capital Management, LLC | 6.28M (2.39%) | 92.23K Increased by +1.47% | Dec 31, 25 |
| 5 | SATTER MANAGEMENT CO., L.P. | 5.75M (2.19%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 6 | Citadel Advisors Llc | 4.67M (1.78%) | 1.48M Increased by +31.72% | Dec 31, 25 |
| 7 | Morgan Stanley - Brokerage Accounts | 4.32M (1.65%) | -1.02M Decreased by -23.74% | Sep 30, 25 |
| 8 | Goldman Sachs Group Inc | 3.93M (1.50%) | 1.21M Increased by +30.75% | Jun 30, 25 |
| 9 | UBS Group AG | 3.65M (1.39%) | 3.01M Increased by +82.46% | Sep 30, 25 |
| 10 | Renaissance Technologies Corp | 3.59M (1.37%) | -359.59K Decreased by -10.01% | Dec 31, 25 |
| 11 | Qube Research & Technologies | 2.99M (1.14%) | -215.42K Decreased by -7.20% | Dec 31, 25 |
| 12 | AIGH Capital Management, LLC | 2.92M (1.12%) | 2.92M Increased by +100.00% | Mar 31, 25 |
| 13 | MPM Oncology Impact Management LP | 2.89M (1.10%) | 0.00 Increased by 0.00% | Sep 30, 25 |
| 14 | Millennium Management LLC | 2.86M (1.09%) | 693.74K Increased by +24.28% | Sep 30, 25 |
| 15 | Franklin Resources Inc | 2.68M (1.02%) | 12.78K Increased by +0.48% | Sep 30, 25 |
| 16 | Northern Trust Corp | 2.49M (0.95%) | 351.29K Increased by +14.13% | Sep 30, 25 |
| 17 | Woodline Partners LP | 2.49M (0.95%) | 2.49M Increased by +100.00% | Mar 31, 25 |
| 18 | Affinity Asset Advisors, LLC | 2.45M (0.93%) | 500.00K Increased by +20.41% | Sep 30, 25 |
| 19 | Amvescap Plc. | 2.40M (0.92%) | 2.02M Increased by +84.08% | Sep 30, 25 |
| 20 | Nuveen, LLC | 2.30M (0.88%) | -407.30K Decreased by -17.70% | Sep 30, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | State Street® SPDR® S&P® Biotech ETF | 8.30M (3.17%) | 46.02K Increased by +0.55% | Feb 28, 26 |
| 2 | Vanguard Total Stock Mkt Idx Inv | 7.91M (3.02%) | 0.00 Increased by 0.00% | Jan 31, 26 |
| 3 | iShares Russell 2000 ETF | 6.32M (2.41%) | 6.32M Increased by +100.00% | Feb 28, 26 |
| 4 | Vanguard US Total Market Shares ETF | 5.95M (2.27%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 5 | SPDR® S&P Biotech ETF | 3.09M (1.18%) | 6.91K Increased by +0.22% | Aug 31, 25 |
| 6 | Vanguard Institutional Extnd Mkt Idx Tr | 2.90M (1.11%) | 15.52K Increased by +0.54% | Jan 31, 26 |
| 7 | Fidelity Small Cap Index | 2.48M (0.95%) | -25.66K Decreased by -1.03% | Dec 31, 25 |
| 8 | Victory Science & Technology | 2.36M (0.90%) | 309.29K Increased by +13.13% | Sep 30, 23 |
| 9 | iShares Russell 2000 Value ETF | 1.97M (0.75%) | 1.97M Increased by +100.00% | Feb 28, 26 |
| 10 | Foord Global Equity (Lux) A | 1.96M (0.75%) | 1.96M Increased by +100.00% | Dec 31, 25 |
| 11 | Foord Global Equity Class B | 1.83M (0.70%) | 1.83M Increased by +100.00% | Dec 31, 25 |
| 12 | Nuveen Quant Small Cap Equity R6 | 1.79M (0.68%) | -276.70K Decreased by -15.45% | Jul 31, 25 |
| 13 | Franklin Biotechnology Discv A(acc)USD | 1.60M (0.61%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 14 | State St Russell Sm/Mid Cp® Indx SL Cl I | 1.46M (0.56%) | 93.00K Increased by +6.37% | Feb 28, 26 |
| 15 | Fidelity Extended Market Index | 1.41M (0.54%) | -5.84K Decreased by -0.42% | Jan 31, 26 |
| 16 | Schwab US Small-Cap ETF™ | 1.28M (0.49%) | 1.13K Increased by +0.09% | Feb 28, 26 |
| 17 | State St Russell Sm/Mid Cp® Indx NL Cl C | 1.26M (0.48%) | 5.51K Increased by +0.44% | Apr 30, 25 |
| 18 | Vanguard Russell 2000 ETF | 1.21M (0.46%) | -34.35K Decreased by -2.85% | Jan 31, 26 |
| 19 | RTW Biotech Opportunities Ord | 1.19M (0.45%) | 1.19M Increased by +100.00% | Dec 31, 24 |
| 20 | Fidelity Enhanced Small Cap ETF | 1.11M (0.42%) | 0.00 Increased by 0.00% | Feb 27, 26 |