| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Sofinnova Ventures | 15.66M (42.10%) | 2.29M Increased by +14.64% | Dec 31, 23 |
| 2 | State Street Corporation | 8.68M (23.34%) | -12.25M Decreased by -141.12% | Dec 31, 23 |
| 3 | BRAIDWELL LP | 6.31M (16.96%) | 1.61M Increased by +25.51% | Sep 30, 23 |
| 4 | Qube Research & Technologies | 3.96M (10.65%) | 3.96M Increased by +100.00% | Dec 31, 23 |
| 5 | Vanguard Group Inc | 2.83M (7.61%) | 261.20K Increased by +9.23% | Dec 31, 25 |
| 6 | GSA Capital Partners LLP | 2.40M (6.45%) | 2.28M Increased by +94.98% | Dec 31, 23 |
| 7 | Assenagon Asset Management SA | 2.31M (6.20%) | 2.23M Increased by +96.78% | Dec 31, 23 |
| 8 | Wells Fargo & Co | 2.30M (6.17%) | -42.05K Decreased by -1.83% | Sep 30, 23 |
| 9 | Readystate Asset Management LP | 2.02M (5.42%) | 252.12K Increased by +12.50% | Dec 31, 23 |
| 10 | Rafferty Asset Management, LLC | 1.68M (4.52%) | 243.02K Increased by +14.46% | Sep 30, 23 |
| 11 | Vanguard Capital Management, LLC | 1.44M (3.87%) | 1.44M Increased by +100.00% | Mar 31, 26 |
| 12 | Oracle Investment Management Inc | 1.42M (3.81%) | -700.00K Decreased by -49.40% | Dec 31, 23 |
| 13 | Vanguard Portfolio Management, LLC | 1.20M (3.21%) | 1.20M Increased by +100.00% | Mar 31, 26 |
| 14 | Siren, L.L.C. | 1.06M (2.86%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 15 | Artal Group S A | 775.00K (2.08%) | 775.00K Increased by +100.00% | Jun 30, 24 |
| 16 | B. Riley Financial Inc | 756.96K (2.04%) | 756.96K Increased by +100.00% | Dec 31, 24 |
| 17 | Marshall Wace Asset Management Ltd | 688.20K (1.85%) | 541.40K Increased by +78.67% | Mar 31, 26 |
| 18 | BlackRock Inc | 545.66K (1.47%) | -12.68K Decreased by -2.32% | Mar 31, 26 |
| 19 | AQR Capital Management LLC | 430.88K (1.16%) | -10.60K Decreased by -2.46% | Jun 30, 25 |
| 20 | Citadel Advisors Llc | 423.24K (1.14%) | 423.24K Increased by +100.00% | Dec 31, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Fidelity® Small Cap Index | 3.36M (9.03%) | 75.72K Increased by +2.25% | Oct 31, 23 |
| 2 | Fidelity® Extended Market Index | 1.95M (5.24%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 3 | Vanguard Total Stock Mkt Idx Inv | 1.16M (3.12%) | 137.50K Increased by +11.86% | Jun 30, 26 |
| 4 | BlackRock Extended Equity Market K | 988.79K (2.66%) | 264.35K Increased by +26.73% | Mar 31, 24 |
| 5 | iShares Russell 2000 ETF | 909.12K (2.44%) | 5.41K Increased by +0.60% | Jun 30, 26 |
| 6 | BlackRock Extended Mkt Composite | 840.73K (2.26%) | 120.19K Increased by +14.30% | Sep 30, 23 |
| 7 | NT R2000 Index Fund - DC - NL - 2 | 830.04K (2.23%) | -9.88K Decreased by -1.19% | Mar 31, 24 |
| 8 | Russell 2000 Index Non-Lendable Fund E | 702.40K (1.89%) | 4.53K Increased by +0.64% | Mar 31, 24 |
| 9 | Vanguard US Total Market Shares ETF | 654.90K (1.76%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 10 | NT R2000 Value Index Fund - L | 650.29K (1.75%) | 94.75K Increased by +14.57% | Dec 31, 23 |
| 11 | BlackRock Russell 2500™ Index F | 578.42K (1.56%) | 238.00 Increased by +0.04% | Mar 31, 24 |
| 12 | Nuveen Equity Index R6 | 543.17K (1.46%) | 0.00 Increased by 0.00% | Mar 31, 24 |
| 13 | Vanguard Strategic Equity Inv | 511.81K (1.38%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 14 | Vanguard Institutional Extnd Mkt Idx Tr | 485.16K (1.30%) | 99.74K Increased by +20.56% | Jun 30, 26 |
| 15 | Nuveen Small Cap Blend Idx R6 | 466.80K (1.26%) | 0.00 Increased by 0.00% | Mar 31, 24 |
| 16 | Vifag 2002 SICAV | 450.00K (1.21%) | 250.00K Increased by +55.56% | Feb 29, 24 |
| 17 | Vanguard Explorer Inv | 290.65K (0.78%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 18 | iShares Russell 2000 Value ETF | 245.61K (0.66%) | -12.84K Decreased by -5.23% | Jun 30, 26 |
| 19 | Fidelity Small Cap Index | 240.65K (0.65%) | -2.96K Decreased by -1.23% | May 31, 25 |
| 20 | Invesco Dorsey Wright SmallCap Momt ETF | 234.92K (0.63%) | 0.00 Increased by 0.00% | Sep 30, 24 |