| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Redmile Group, LLC | 15.67M (14.53%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 2 | Prosight Management, LP | 10.47M (9.71%) | 924.77K Increased by +8.83% | Jun 30, 25 |
| 3 | Point72 Asset Management, L.P. | 7.76M (7.20%) | 7.76M Increased by +100.00% | Jun 30, 25 |
| 4 | Orbimed Advisors, LLC | 5.91M (5.48%) | -61.10K Decreased by -1.03% | Jun 30, 25 |
| 5 | BlackRock Inc | 4.52M (4.19%) | -392.29K Decreased by -8.68% | Jun 30, 25 |
| 6 | Sio Capital Management, LLC | 3.29M (3.06%) | -726.17K Decreased by -22.04% | Sep 30, 23 |
| 7 | Morgan Stanley - Brokerage Accounts | 3.05M (2.83%) | 25.99K Increased by +0.85% | Jun 30, 25 |
| 8 | Citadel Advisors Llc | 2.90M (2.69%) | -271.73K Decreased by -9.38% | Sep 30, 23 |
| 9 | Heights Capital Management Inc | 2.83M (2.63%) | 2.83M Increased by +100.00% | Jun 30, 25 |
| 10 | Nantahala Capital Management, LLC | 2.27M (2.10%) | 2.27M Increased by +100.00% | Jun 30, 25 |
| 11 | Bank of America Corp | 2.20M (2.04%) | 397.90K Increased by +18.09% | Jun 30, 25 |
| 12 | SILVERARC CAPITAL MANAGEMENT, LLC | 1.80M (1.67%) | 26.31K Increased by +1.47% | Sep 30, 24 |
| 13 | Goldman Sachs Group Inc | 1.54M (1.43%) | -40.51K Decreased by -2.63% | Jun 30, 25 |
| 14 | Junked Platinum Investment Management Ltd | 1.39M (1.29%) | -650.82K Decreased by -46.91% | Jun 30, 25 |
| 15 | State Street Corp | 1.23M (1.15%) | 23.13K Increased by +1.87% | Jun 30, 25 |
| 16 | AlphaCentric Advisors, LLC | 1.07M (0.99%) | 290.47K Increased by +27.19% | Sep 30, 23 |
| 17 | Artal Group S A | 1.02M (0.94%) | 1.02M Increased by +100.00% | Jun 30, 24 |
| 18 | Adage Capital Partners Gp LLC | 1.00M (0.93%) | 1.00M Increased by +100.00% | Mar 31, 24 |
| 19 | Geode Capital Management, LLC | 858.80K (0.80%) | -110.95K Decreased by -12.92% | Jun 30, 25 |
| 20 | Woodline Partners LP | 842.90K (0.78%) | 27.37K Increased by +3.25% | Jun 30, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Biotech Growth Ord | 2.13M (1.98%) | 0.00 Increased by 0.00% | May 31, 25 |
| 2 | iShares Russell 2000 ETF | 1.81M (1.68%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 3 | Fidelity Small Cap Index | 726.86K (0.67%) | -94.23K Decreased by -12.96% | Jun 30, 25 |
| 4 | Pictet-Global Megatrend Sel I USD | 681.58K (0.63%) | 7.34K Increased by +1.08% | May 31, 23 |
| 5 | iShares Russell 2000 Growth ETF | 628.23K (0.58%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 6 | Pictet-Biotech P USD | 588.57K (0.55%) | 6.33K Increased by +1.08% | May 31, 23 |
| 7 | iShares Biotechnology ETF | 460.15K (0.43%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 8 | State St Russell Sm/Mid Cp® Indx NL Cl C | 401.24K (0.37%) | 0.00 Increased by 0.00% | Apr 30, 25 |
| 9 | State St Russell Sm/Mid Cp® Indx SL Cl I | 401.24K (0.37%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 10 | Vanguard Russell 2000 ETF | 344.65K (0.32%) | -24.16K Decreased by -7.01% | Jul 31, 25 |
| 11 | State St Russell Sm Cap® Indx SL Cl I | 305.70K (0.28%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 12 | iShares Russell 2000 Value ETF | 286.42K (0.27%) | 0.00 Increased by 0.00% | May 31, 25 |
| 13 | Schwab Small Cap Index | 182.01K (0.17%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 14 | NT R2000 Index Fund - NL | 175.28K (0.16%) | -24.07K Decreased by -13.73% | Jun 30, 25 |
| 15 | iShares Micro-Cap ETF | 163.68K (0.15%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 16 | NT R2000 Index Fund - DC - NL - 2 | 159.25K (0.15%) | 8.95K Increased by +5.62% | Mar 31, 25 |
| 17 | Protea Sectoral Hlthcare Opps P USD Acc | 151.09K (0.14%) | -30.00K Decreased by -19.86% | Jul 31, 24 |
| 18 | US SMID CAP EQ INDEX | 148.04K (0.14%) | 34.75K Increased by +23.47% | Sep 30, 24 |
| 19 | SPDR® Russell 2000 US Small Cap ETF | 139.82K (0.13%) | 676.00 Increased by +0.48% | Aug 31, 25 |
| 20 | NT R2000 Index Fund - DC - NL - 3 | 139.75K (0.13%) | -19.50K Decreased by -13.96% | Jun 30, 25 |