| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Redmile Group, LLC | 15.47M (15.41%) | -196.23K Decreased by -1.27% | Mar 31, 26 |
| 2 | TCG Crossover Management, LLC | 11.39M (11.34%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 3 | Prosight Management, LP | 8.30M (8.27%) | -177.34K Decreased by -2.14% | Mar 31, 26 |
| 4 | BlackRock Inc | 6.25M (6.23%) | 823.44K Increased by +13.17% | Mar 31, 26 |
| 5 | Eventide Asset Management, LLC | 5.70M (5.68%) | 2.34M Increased by +41.00% | Mar 31, 26 |
| 6 | Nantahala Capital Management, LLC | 5.60M (5.57%) | 122.00K Increased by +2.18% | Mar 31, 26 |
| 7 | Morgan Stanley - Brokerage Accounts | 3.81M (3.80%) | 42.84K Increased by +1.12% | Mar 31, 26 |
| 8 | Point72 Asset Management, L.P. | 3.38M (3.37%) | -1.63M Decreased by -48.27% | Mar 31, 26 |
| 9 | Sio Capital Management, LLC | 3.29M (3.28%) | -726.17K Decreased by -22.04% | Sep 30, 23 |
| 10 | Millennium Management LLC | 3.12M (3.11%) | 2.79M Increased by +89.47% | Mar 31, 26 |
| 11 | Heights Capital Management Inc | 2.83M (2.82%) | 2.83M Increased by +100.00% | Jun 30, 25 |
| 12 | SILVERARC CAPITAL MANAGEMENT, LLC | 1.80M (1.79%) | 26.31K Increased by +1.47% | Sep 30, 24 |
| 13 | The Goldman Sachs Group Inc | 1.65M (1.65%) | 12.15K Increased by +0.74% | Mar 31, 26 |
| 14 | State Street Corp | 1.57M (1.56%) | 159.34K Increased by +10.17% | Mar 31, 26 |
| 15 | Goldman Sachs Group Inc | 1.54M (1.54%) | -40.51K Decreased by -2.63% | Jun 30, 25 |
| 16 | Lynx1 Capital Management, LP | 1.33M (1.32%) | 1.33M Increased by +100.00% | Sep 30, 25 |
| 17 | Bank of America Corp | 1.33M (1.32%) | 26.43K Increased by +1.99% | Mar 31, 26 |
| 18 | Orbimed Advisors, LLC | 1.32M (1.31%) | -4.50M Decreased by -341.79% | Mar 31, 26 |
| 19 | Geode Capital Management, LLC | 1.20M (1.20%) | 207.23K Increased by +17.22% | Mar 31, 26 |
| 20 | Vanguard Group Inc | 1.13M (1.12%) | 535.63K Increased by +47.42% | Dec 31, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Eventide Healthcare & Life Sciences I | 5.70M (5.68%) | 2.34M Increased by +41.00% | Mar 31, 26 |
| 2 | iShares Russell 2000 ETF | 2.45M (2.44%) | 22.62K Increased by +0.92% | May 29, 26 |
| 3 | Biotech Growth Ord | 1.05M (1.04%) | -832.72K Decreased by -79.46% | Feb 28, 26 |
| 4 | Fidelity Small Cap Index | 997.65K (0.99%) | 156.38K Increased by +15.67% | Mar 31, 26 |
| 5 | iShares Russell 2000 Growth ETF | 822.60K (0.82%) | -5.36K Decreased by -0.65% | May 29, 26 |
| 6 | Pictet-Global Megatrend Sel I USD | 681.58K (0.68%) | 7.34K Increased by +1.08% | May 31, 23 |
| 7 | iShares Biotechnology ETF | 657.74K (0.66%) | 12.60K Increased by +1.92% | May 29, 26 |
| 8 | State St Russell Sm/Mid Cp® Indx SL Cl I | 608.04K (0.61%) | 0.00 Increased by 0.00% | May 31, 26 |
| 9 | Pictet-Biotech P USD | 588.57K (0.59%) | 6.33K Increased by +1.08% | May 31, 23 |
| 10 | Russell 2000 Equity Index Fund B | 571.78K (0.57%) | 88.32K Increased by +15.45% | Dec 31, 25 |
| 11 | Vanguard Russell 2000 ETF | 515.30K (0.51%) | 13.35K Increased by +2.59% | Apr 30, 26 |
| 12 | International Biotechnology Ord | 418.78K (0.42%) | 0.00 Increased by 0.00% | Feb 28, 26 |
| 13 | State St Russell Sm/Mid Cp® Indx NL Cl C | 401.24K (0.40%) | 0.00 Increased by 0.00% | Apr 30, 25 |
| 14 | State St Russell Sm Cap® Idx SL Cl I | 319.50K (0.32%) | 0.00 Increased by 0.00% | May 31, 26 |
| 15 | State St Russell Sm Cap® Indx SL Cl I | 319.50K (0.32%) | 0.00 Increased by 0.00% | Apr 30, 26 |
| 16 | Vanguard US Momentum Factor ETF | 316.58K (0.32%) | -85.29K Decreased by -26.94% | Mar 31, 26 |
| 17 | iShares Russell 2000 Value ETF | 286.42K (0.29%) | 0.00 Increased by 0.00% | May 31, 25 |
| 18 | iShares Micro-Cap ETF | 262.54K (0.26%) | 0.00 Increased by 0.00% | May 29, 26 |
| 19 | Schwab Small Cap Index | 224.36K (0.22%) | 0.00 Increased by 0.00% | Apr 30, 26 |
| 20 | Lazard Baylight US Small Cap Equity | 220.38K (0.22%) | 220.38K Increased by +100.00% | Mar 31, 26 |