| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Redmile Group, LLC | 15.67M (21.44%) | -2.49K Decreased by -0.02% | Dec 31, 24 |
| 2 | Prosight Management, LP | 9.52M (13.02%) | -121.24K Decreased by -1.27% | Dec 31, 24 |
| 3 | Orbimed Advisors, LLC | 5.97M (8.17%) | 1.43M Increased by +24.04% | Dec 31, 24 |
| 4 | BlackRock Inc | 5.01M (6.86%) | 612.72K Increased by +12.23% | Dec 31, 24 |
| 5 | Morgan Stanley - Brokerage Accounts | 3.96M (5.41%) | 915.38K Increased by +23.14% | Dec 31, 24 |
| 6 | Sio Capital Management, LLC | 3.29M (4.51%) | -726.17K Decreased by -22.04% | Sep 30, 23 |
| 7 | Citadel Advisors Llc | 2.90M (3.97%) | -271.73K Decreased by -9.38% | Sep 30, 23 |
| 8 | Woodline Partners LP | 1.93M (2.65%) | 1.93M Increased by +100.00% | Dec 31, 24 |
| 9 | SILVERARC CAPITAL MANAGEMENT, LLC | 1.80M (2.46%) | 26.31K Increased by +1.47% | Sep 30, 24 |
| 10 | Goldman Sachs Group Inc | 1.67M (2.29%) | -15.42K Decreased by -0.92% | Dec 31, 24 |
| 11 | Junked Platinum Investment Management Ltd | 1.61M (2.21%) | 168.04K Increased by +10.42% | Dec 31, 24 |
| 12 | Bank of America Corp | 1.29M (1.77%) | -1.21M Decreased by -93.45% | Dec 31, 24 |
| 13 | State Street Corp | 1.19M (1.63%) | 82.18K Increased by +6.92% | Dec 31, 24 |
| 14 | AlphaCentric Advisors, LLC | 1.07M (1.46%) | 290.47K Increased by +27.19% | Sep 30, 23 |
| 15 | Artal Group S A | 1.02M (1.39%) | 1.02M Increased by +100.00% | Jun 30, 24 |
| 16 | Adage Capital Partners Gp LLC | 1.00M (1.37%) | 1.00M Increased by +100.00% | Mar 31, 24 |
| 17 | Geode Capital Management, LLC | 963.11K (1.32%) | 9.94K Increased by +1.03% | Dec 31, 24 |
| 18 | UBS Group AG | 884.52K (1.21%) | 844.74K Increased by +95.50% | Dec 31, 24 |
| 19 | Vantage Consulting Group Inc. | 850.74K (1.16%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 20 | Blue Owl Capital Holdings LP | 733.57K (1.00%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Biotech Growth Ord | 2.13M (2.92%) | 0.00 Increased by 0.00% | Jan 31, 25 |
| 2 | iShares Russell 2000 ETF | 1.90M (2.60%) | -15.41K Decreased by -0.81% | Apr 29, 25 |
| 3 | Fidelity Small Cap Index | 815.10K (1.12%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 4 | Pictet-Global Megatrend Sel I USD | 681.58K (0.93%) | 7.34K Increased by +1.08% | May 31, 23 |
| 5 | Pictet-Biotech P USD | 588.57K (0.81%) | 6.33K Increased by +1.08% | May 31, 23 |
| 6 | iShares Biotechnology ETF | 466.05K (0.64%) | 1.07K Increased by +0.23% | Apr 30, 25 |
| 7 | iShares Russell 2000 Growth ETF | 431.35K (0.59%) | 0.00 Increased by 0.00% | Apr 30, 25 |
| 8 | State St Russell Sm/Mid Cp® Indx NL Cl C | 401.24K (0.55%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 9 | State St Russell Sm/Mid Cp® Indx SL Cl I | 401.24K (0.55%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 10 | Vanguard Russell 2000 ETF | 378.99K (0.52%) | 8.58K Increased by +2.26% | Mar 31, 25 |
| 11 | State St Russell Sm Cap® Indx SL Cl I | 305.70K (0.42%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 12 | iShares Russell 2000 Value ETF | 296.87K (0.41%) | -1.00K Decreased by -0.34% | Apr 30, 25 |
| 13 | NT R2000 Index Fund - NL | 199.34K (0.27%) | 15.11K Increased by +7.58% | Mar 31, 25 |
| 14 | Schwab Small Cap Index | 194.26K (0.27%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 15 | iShares Micro-Cap ETF | 178.42K (0.24%) | 0.00 Increased by 0.00% | Apr 30, 25 |
| 16 | NT R2000 Index Fund - DC - NL - 2 | 159.25K (0.22%) | 8.95K Increased by +5.62% | Mar 31, 25 |
| 17 | NT R2000 Index Fund - DC - NL - 3 | 159.25K (0.22%) | 8.95K Increased by +5.62% | Mar 31, 25 |
| 18 | SPDR® Russell 2000 US Small Cap ETF | 154.67K (0.21%) | -18.00K Decreased by -11.64% | Mar 31, 25 |
| 19 | Protea Sectoral Hlthcare Opps P USD Acc | 151.09K (0.21%) | -30.00K Decreased by -19.86% | Jul 31, 24 |
| 20 | US SMID CAP EQ INDEX | 148.04K (0.20%) | 34.75K Increased by +23.47% | Sep 30, 24 |