| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Redmile Group, LLC | 15.67M (19.80%) | -2.49K Decreased by -0.02% | Dec 31, 24 |
| 2 | Prosight Management, LP | 9.54M (12.06%) | 28.00K Increased by +0.29% | Mar 31, 25 |
| 3 | Orbimed Advisors, LLC | 5.97M (7.54%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 4 | BlackRock Inc | 4.91M (6.21%) | -98.23K Decreased by -2.00% | Mar 31, 25 |
| 5 | Sio Capital Management, LLC | 3.29M (4.16%) | -726.17K Decreased by -22.04% | Sep 30, 23 |
| 6 | Morgan Stanley - Brokerage Accounts | 3.02M (3.82%) | -936.59K Decreased by -31.02% | Mar 31, 25 |
| 7 | Citadel Advisors Llc | 2.90M (3.66%) | -271.73K Decreased by -9.38% | Sep 30, 23 |
| 8 | Junked Platinum Investment Management Ltd | 2.04M (2.58%) | 425.53K Increased by +20.88% | Mar 31, 25 |
| 9 | Bank of America Corp | 1.80M (2.28%) | 509.91K Increased by +28.31% | Mar 31, 25 |
| 10 | SILVERARC CAPITAL MANAGEMENT, LLC | 1.80M (2.27%) | 26.31K Increased by +1.47% | Sep 30, 24 |
| 11 | Goldman Sachs Group Inc | 1.58M (2.00%) | -90.06K Decreased by -5.69% | Mar 31, 25 |
| 12 | State Street Corp | 1.21M (1.53%) | 23.15K Increased by +1.91% | Mar 31, 25 |
| 13 | AlphaCentric Advisors, LLC | 1.07M (1.35%) | 290.47K Increased by +27.19% | Sep 30, 23 |
| 14 | Artal Group S A | 1.02M (1.29%) | 1.02M Increased by +100.00% | Jun 30, 24 |
| 15 | Adage Capital Partners Gp LLC | 1.00M (1.26%) | 1.00M Increased by +100.00% | Mar 31, 24 |
| 16 | Geode Capital Management, LLC | 969.75K (1.23%) | 6.64K Increased by +0.68% | Mar 31, 25 |
| 17 | UBS Group AG | 884.52K (1.12%) | 844.74K Increased by +95.50% | Dec 31, 24 |
| 18 | Vantage Consulting Group Inc. | 850.74K (1.08%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 19 | Woodline Partners LP | 815.53K (1.03%) | -1.12M Decreased by -137.12% | Mar 31, 25 |
| 20 | Blue Owl Capital Holdings LP | 733.57K (0.93%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Biotech Growth Ord | 2.13M (2.69%) | 0.00 Increased by 0.00% | Jan 31, 25 |
| 2 | iShares Russell 2000 ETF | 1.90M (2.40%) | 321.00 Increased by +0.02% | Apr 30, 25 |
| 3 | Fidelity Small Cap Index | 815.10K (1.03%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 4 | Pictet-Global Megatrend Sel I USD | 681.58K (0.86%) | 7.34K Increased by +1.08% | May 31, 23 |
| 5 | Pictet-Biotech P USD | 588.57K (0.74%) | 6.33K Increased by +1.08% | May 31, 23 |
| 6 | iShares Biotechnology ETF | 466.05K (0.59%) | 1.07K Increased by +0.23% | Apr 30, 25 |
| 7 | iShares Russell 2000 Growth ETF | 431.35K (0.55%) | 0.00 Increased by 0.00% | Apr 30, 25 |
| 8 | Vanguard Russell 2000 ETF | 401.48K (0.51%) | 22.50K Increased by +5.60% | Apr 30, 25 |
| 9 | State St Russell Sm/Mid Cp® Indx NL Cl C | 401.24K (0.51%) | 0.00 Increased by 0.00% | Apr 30, 25 |
| 10 | State St Russell Sm/Mid Cp® Indx SL Cl I | 401.24K (0.51%) | 0.00 Increased by 0.00% | Apr 30, 25 |
| 11 | State St Russell Sm Cap® Indx SL Cl I | 305.70K (0.39%) | 0.00 Increased by 0.00% | Apr 30, 25 |
| 12 | iShares Russell 2000 Value ETF | 296.87K (0.38%) | -1.00K Decreased by -0.34% | Apr 30, 25 |
| 13 | NT R2000 Index Fund - NL | 199.34K (0.25%) | 15.11K Increased by +7.58% | Mar 31, 25 |
| 14 | Schwab Small Cap Index | 194.26K (0.25%) | 0.00 Increased by 0.00% | Apr 30, 25 |
| 15 | iShares Micro-Cap ETF | 178.42K (0.23%) | 0.00 Increased by 0.00% | Apr 30, 25 |
| 16 | NT R2000 Index Fund - DC - NL - 2 | 159.25K (0.20%) | 8.95K Increased by +5.62% | Mar 31, 25 |
| 17 | NT R2000 Index Fund - DC - NL - 3 | 159.25K (0.20%) | 8.95K Increased by +5.62% | Mar 31, 25 |
| 18 | Protea Sectoral Hlthcare Opps P USD Acc | 151.09K (0.19%) | -30.00K Decreased by -19.86% | Jul 31, 24 |
| 19 | US SMID CAP EQ INDEX | 148.04K (0.19%) | 34.75K Increased by +23.47% | Sep 30, 24 |
| 20 | Russell 2500™ Index Fund F | 148.00K (0.19%) | -32.00 Decreased by -0.02% | Mar 31, 25 |