| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | BML Capital Management LLC | 14.25M (19.61%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 2 | Adage Capital Partners Gp LLC | 9.63M (13.25%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 3 | Vivo Capital, LLC | 8.89M (12.23%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 4 | Bvf Inc | 7.06M (9.72%) | 3.70M Increased by +52.43% | Sep 30, 23 |
| 5 | Wellington Management Company LLP | 6.98M (9.61%) | -658.02K Decreased by -9.43% | Sep 30, 23 |
| 6 | Vanguard Group Inc | 6.66M (9.17%) | 1.69M Increased by +25.39% | Jun 30, 25 |
| 7 | Rock Springs Capital Management LP | 4.77M (6.56%) | -277.00K Decreased by -5.81% | Jun 30, 25 |
| 8 | RA Capital Management, LLC | 4.67M (6.42%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 9 | Millennium Management LLC | 4.13M (5.69%) | 2.18M Increased by +52.61% | Mar 31, 25 |
| 10 | Decheng Capital LLC | 4.04M (5.56%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 11 | Foresite Capital Management IV, LLC | 2.81M (3.87%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 12 | D. E. Shaw & Co LP | 2.80M (3.85%) | -144.23K Decreased by -5.15% | Jun 30, 25 |
| 13 | HHG PLC | 2.80M (3.85%) | 2.80M Increased by +100.00% | Dec 31, 24 |
| 14 | Stonepine Capital Management Llc | 2.46M (3.38%) | 531.43K Increased by +21.61% | Sep 30, 24 |
| 15 | Morgan Stanley - Brokerage Accounts | 2.42M (3.32%) | 1.34M Increased by +55.63% | Mar 31, 25 |
| 16 | Samsara BioCapital, LLC | 2.39M (3.28%) | 1.69M Increased by +70.81% | Dec 31, 24 |
| 17 | Marshall Wace Asset Management Ltd | 2.29M (3.16%) | -20.48K Decreased by -0.89% | Jun 30, 25 |
| 18 | Logos Global Management LP | 2.22M (3.06%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 19 | Acadian Asset Management LLC | 2.20M (3.02%) | 2.19M Increased by +99.87% | Mar 31, 25 |
| 20 | Trium Capital LLP | 1.91M (2.63%) | 20.94K Increased by +1.09% | Sep 30, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 3.18M (4.37%) | -70.07K Decreased by -2.21% | Jul 31, 25 |
| 2 | Vanguard US Total Market Shares ETF | 2.12M (2.91%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 3 | iShares Russell 2000 ETF | 1.78M (2.45%) | -33.91K Decreased by -1.90% | Jul 31, 25 |
| 4 | Vanguard Institutional Extnd Mkt Idx Tr | 1.22M (1.68%) | -555.76K Decreased by -45.57% | Jul 31, 25 |
| 5 | Xtrackers S&P 500 Swap ETF 1C | 923.31K (1.27%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 6 | Fidelity Small Cap Index | 905.29K (1.25%) | 905.29K Increased by +100.00% | Jun 30, 25 |
| 7 | iShares Russell 2000 Value ETF | 782.60K (1.08%) | 581.00 Increased by +0.07% | Jul 31, 25 |
| 8 | Fidelity® Small Cap Index | 671.70K (0.92%) | 20.07K Increased by +2.99% | Oct 31, 23 |
| 9 | Vanguard Strategic Small-Cap Equity Inv | 592.57K (0.82%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 10 | iShares Russell 2000 Growth ETF | 587.67K (0.81%) | 0.00 Increased by 0.00% | May 29, 24 |
| 11 | Fidelity Extended Market Index | 584.07K (0.80%) | -1.52K Decreased by -0.26% | Jun 30, 25 |
| 12 | SQUAD Aguja Opportunities I | 500.00K (0.69%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 13 | iShares Biotechnology ETF | 481.67K (0.66%) | 490.00 Increased by +0.10% | Nov 27, 24 |
| 14 | Vanguard Russell 2000 ETF | 434.47K (0.60%) | -27.61K Decreased by -6.35% | Jul 31, 25 |
| 15 | Fidelity® Extended Market Index | 336.96K (0.46%) | 33.29K Increased by +9.88% | Nov 30, 23 |
| 16 | State St Russell Sm Cap® Indx SL Cl I | 320.30K (0.44%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 17 | Vanguard VIF Small Co Gr | 282.35K (0.39%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 18 | Schwab US Small-Cap ETF™ | 261.78K (0.36%) | 0.00 Increased by 0.00% | Aug 31, 24 |
| 19 | State St Russell Sm/Mid Cp® Indx NL Cl C | 250.34K (0.34%) | -164.95K Decreased by -65.89% | Jun 30, 24 |
| 20 | Northwestern Mutual Ser Small Cap Gr Stk | 241.68K (0.33%) | 9.54K Increased by +3.95% | Sep 30, 23 |