| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | BML Capital Management LLC | 14.25M (21.52%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 2 | Adage Capital Partners Gp LLC | 9.63M (14.54%) | 9.63M Increased by +100.00% | Dec 31, 24 |
| 3 | Vivo Capital, LLC | 8.89M (13.43%) | 8.89M Increased by +100.00% | Dec 31, 24 |
| 4 | Bvf Inc | 7.06M (10.67%) | 3.70M Increased by +52.43% | Sep 30, 23 |
| 5 | Wellington Management Company LLP | 6.98M (10.54%) | -658.02K Decreased by -9.43% | Sep 30, 23 |
| 6 | Rock Springs Capital Management LP | 6.20M (9.37%) | 3.45M Increased by +55.62% | Dec 31, 24 |
| 7 | RA Capital Management, LLC | 4.67M (7.05%) | 4.67M Increased by +100.00% | Dec 31, 24 |
| 8 | Vanguard Group Inc | 4.33M (6.53%) | -360.24K Decreased by -8.33% | Dec 31, 24 |
| 9 | D. E. Shaw & Co LP | 3.29M (4.97%) | -78.22K Decreased by -2.38% | Dec 31, 24 |
| 10 | Foresite Capital Management IV, LLC | 2.81M (4.24%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 11 | HHG PLC | 2.80M (4.23%) | 2.80M Increased by +100.00% | Dec 31, 24 |
| 12 | Marshall Wace Asset Management Ltd | 2.63M (3.98%) | 2.63M Increased by +100.00% | Dec 31, 24 |
| 13 | Stonepine Capital Management Llc | 2.46M (3.71%) | 531.43K Increased by +21.61% | Sep 30, 24 |
| 14 | Samsara BioCapital, LLC | 2.39M (3.60%) | 1.69M Increased by +70.81% | Dec 31, 24 |
| 15 | Decheng Capital LLC | 2.27M (3.42%) | 2.27M Increased by +100.00% | Dec 31, 24 |
| 16 | Logos Global Management LP | 2.22M (3.36%) | 2.22M Increased by +100.00% | Dec 31, 24 |
| 17 | Acadian Asset Management LLC | 2.14M (3.23%) | -216.04K Decreased by -10.12% | Mar 31, 24 |
| 18 | Millennium Management LLC | 1.96M (2.96%) | -1.05M Decreased by -53.42% | Dec 31, 24 |
| 19 | Trium Capital LLP | 1.91M (2.89%) | 20.94K Increased by +1.09% | Sep 30, 24 |
| 20 | Velan Capital Investment Management LP | 1.76M (2.66%) | 1.76M Increased by +100.00% | Dec 31, 23 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 2.12M (3.20%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 2 | Vanguard US Total Market Shares ETF | 2.12M (3.20%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 3 | Vanguard Institutional Extnd Mkt Idx Tr | 1.78M (2.68%) | 721.94K Increased by +40.66% | Mar 31, 25 |
| 4 | iShares Russell 2000 ETF | 1.63M (2.46%) | -18.18K Decreased by -1.12% | May 29, 24 |
| 5 | Xtrackers S&P 500 Swap ETF 1C | 923.31K (1.39%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 6 | Fidelity Small Cap Index | 700.66K (1.06%) | 25.48K Increased by +3.64% | Jun 30, 24 |
| 7 | Fidelity® Small Cap Index | 671.70K (1.01%) | 20.07K Increased by +2.99% | Oct 31, 23 |
| 8 | Fidelity Extended Market Index | 593.83K (0.90%) | 204.33K Increased by +34.41% | Mar 31, 25 |
| 9 | Vanguard Strategic Small-Cap Equity Inv | 592.57K (0.89%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 10 | iShares Russell 2000 Growth ETF | 587.67K (0.89%) | 0.00 Increased by 0.00% | May 29, 24 |
| 11 | SQUAD Aguja Opportunities I | 500.00K (0.76%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 12 | iShares Biotechnology ETF | 481.67K (0.73%) | 490.00 Increased by +0.10% | Nov 27, 24 |
| 13 | Fidelity® Extended Market Index | 336.96K (0.51%) | 33.29K Increased by +9.88% | Nov 30, 23 |
| 14 | Vanguard VIF Small Co Gr | 282.35K (0.43%) | -187.87K Decreased by -66.54% | Mar 31, 25 |
| 15 | Schwab US Small-Cap ETF™ | 261.78K (0.40%) | 0.00 Increased by 0.00% | Aug 31, 24 |
| 16 | Vanguard Russell 2000 ETF | 258.83K (0.39%) | 862.00 Increased by +0.33% | Apr 30, 24 |
| 17 | State St Russell Sm/Mid Cp® Indx NL Cl C | 250.34K (0.38%) | -164.95K Decreased by -65.89% | Jun 30, 24 |
| 18 | Northwestern Mutual Ser Small Cap Gr Stk | 241.68K (0.37%) | 9.54K Increased by +3.95% | Sep 30, 23 |
| 19 | State St Russell Sm Cap® Indx SL Cl I | 236.38K (0.36%) | 0.00 Increased by 0.00% | Apr 30, 24 |
| 20 | Extended Equity Market Fund K | 228.94K (0.35%) | 98.97K Increased by +43.23% | Mar 31, 25 |