| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | RA Capital Management, LLC | 14.93M (41.93%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 2 | Sands Capital Ventures, LLC | 3.42M (9.60%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 3 | Franklin Resources Inc | 3.08M (8.64%) | -64.90K Decreased by -2.11% | Jun 30, 25 |
| 4 | Deep Track Capital, LP | 2.51M (7.06%) | -1.40M Decreased by -55.84% | Sep 30, 23 |
| 5 | Boxer Capital LLC | 2.21M (6.20%) | 2.21M Increased by +100.00% | Sep 30, 23 |
| 6 | FMR Inc | 2.03M (5.70%) | 4.11K Increased by +0.20% | Jun 30, 25 |
| 7 | Millennium Management LLC | 1.95M (5.48%) | 814.90K Increased by +41.79% | Jun 30, 25 |
| 8 | Rock Springs Capital Management LP | 1.84M (5.16%) | -461.14K Decreased by -25.08% | Dec 31, 24 |
| 9 | Vanguard Group Inc | 1.69M (4.74%) | -247.64K Decreased by -14.66% | Jun 30, 25 |
| 10 | Knollwood Investment Advisory LLC | 1.63M (4.57%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 11 | Great Point Partners LLC | 1.07M (3.02%) | 22.83K Increased by +2.13% | Sep 30, 23 |
| 12 | Pathstone Holdings LLC | 1.06M (2.97%) | -28.00K Decreased by -2.65% | Jun 30, 25 |
| 13 | Alyeska Investment Group, L.P. | 939.60K (2.64%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 14 | ADAR1 Capital Management LLC | 916.18K (2.57%) | 770.00K Increased by +84.04% | Jun 30, 25 |
| 15 | LAURION CAPITAL MANAGEMENT LP | 867.05K (2.43%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 16 | T. Rowe Price Associates, Inc. | 849.62K (2.39%) | -196.75K Decreased by -23.16% | Sep 30, 24 |
| 17 | JPMorgan Chase & Co | 832.27K (2.34%) | -105.64K Decreased by -12.69% | Mar 31, 25 |
| 18 | Hudson Bay Capital Management LP | 825.00K (2.32%) | 55.00K Increased by +6.67% | Jun 30, 25 |
| 19 | Altium Capital Management, LP | 650.00K (1.83%) | 650.00K Increased by +100.00% | Sep 30, 23 |
| 20 | JANE STREET GROUP, LLC | 604.62K (1.70%) | 587.83K Increased by +97.22% | Dec 31, 23 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Franklin Biotechnology Discv A(acc)USD | 1.48M (4.15%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 2 | Fidelity Select Health Care | 1.14M (3.20%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 3 | Vanguard Total Stock Mkt Idx Inv | 1.12M (3.15%) | -24.52K Decreased by -2.19% | Jul 31, 25 |
| 4 | iShares Russell 2000 ETF | 971.80K (2.73%) | 0.00 Increased by 0.00% | May 31, 25 |
| 5 | Franklin Biotechnology Discovery A | 826.40K (2.32%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 6 | Franklin Small Cap Growth SMA | 771.94K (2.17%) | 771.94K Increased by +100.00% | Jun 30, 25 |
| 7 | Franklin US Small Cap Growth Equity | 771.94K (2.17%) | 3.97K Increased by +0.51% | Jun 30, 25 |
| 8 | Franklin Small Cap Growth Adv | 708.38K (1.99%) | -59.59K Decreased by -8.41% | Jun 30, 25 |
| 9 | Fidelity Advisor Health Care I | 700.00K (1.97%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 10 | Fidelity Small Cap Index | 408.40K (1.15%) | 0.00 Increased by 0.00% | May 31, 25 |
| 11 | iShares Russell 2000 Value ETF | 364.32K (1.02%) | 0.00 Increased by 0.00% | May 31, 25 |
| 12 | Vanguard Institutional Extnd Mkt Idx Tr | 324.37K (0.91%) | -147.81K Decreased by -45.57% | Jul 31, 25 |
| 13 | A4Investments SICAV SIF ACCI IlanaA2EURH | 225.00K (0.63%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 14 | Vanguard Russell 2000 ETF | 209.36K (0.59%) | 1.88K Increased by +0.90% | May 31, 25 |
| 15 | State St Russell Sm Cap® Indx SL Cl I | 205.20K (0.58%) | 0.00 Increased by 0.00% | May 31, 25 |
| 16 | Fidelity VIP Health Care Initial | 180.00K (0.51%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 17 | Fidelity Extended Market Index | 168.84K (0.47%) | -1.39K Decreased by -0.82% | Jul 31, 25 |
| 18 | Vifag 2002 SICAV | 150.00K (0.42%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 19 | Fidelity® Extended Market Index | 137.97K (0.39%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 20 | UBC Russell 3000 Index Trust - C | 121.97K (0.34%) | 108.70K Increased by +89.11% | Mar 31, 25 |