| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | RA Capital Management, LLC | 14.93M (51.01%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 2 | Sands Capital Ventures, LLC | 3.42M (11.67%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 3 | Deep Track Capital, LP | 2.51M (8.58%) | -1.40M Decreased by -55.84% | Sep 30, 23 |
| 4 | Franklin Resources Inc | 2.31M (7.87%) | -771.94K Decreased by -33.49% | Sep 30, 25 |
| 5 | Boxer Capital LLC | 2.21M (7.54%) | 2.21M Increased by +100.00% | Sep 30, 23 |
| 6 | FMR Inc | 2.03M (6.93%) | -1.83K Decreased by -0.09% | Dec 31, 25 |
| 7 | Rock Springs Capital Management LP | 1.84M (6.28%) | -461.14K Decreased by -25.08% | Dec 31, 24 |
| 8 | Vanguard Group Inc | 1.65M (5.65%) | 2.30K Increased by +0.14% | Dec 31, 25 |
| 9 | Knollwood Investment Advisory LLC | 1.63M (5.56%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 10 | Great Point Partners LLC | 1.07M (3.67%) | 22.83K Increased by +2.13% | Sep 30, 23 |
| 11 | Alyeska Investment Group, L.P. | 939.60K (3.21%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 12 | ADAR1 Capital Management LLC | 891.18K (3.04%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 13 | LAURION CAPITAL MANAGEMENT LP | 867.05K (2.96%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 14 | Pathstone Holdings LLC | 859.11K (2.93%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 15 | T. Rowe Price Associates, Inc. | 849.62K (2.90%) | -196.75K Decreased by -23.16% | Sep 30, 24 |
| 16 | JPMorgan Chase & Co | 832.27K (2.84%) | -105.64K Decreased by -12.69% | Mar 31, 25 |
| 17 | Hudson Bay Capital Management LP | 725.00K (2.48%) | -4.00 Decreased by -0.00% | Dec 31, 25 |
| 18 | Altium Capital Management, LP | 650.00K (2.22%) | 650.00K Increased by +100.00% | Sep 30, 23 |
| 19 | JANE STREET GROUP, LLC | 604.62K (2.07%) | 587.83K Increased by +97.22% | Dec 31, 23 |
| 20 | Millennium Management LLC | 584.14K (2.00%) | -17.57K Decreased by -3.01% | Dec 31, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Franklin Biotechnology Discv A(acc)USD | 1.48M (5.05%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 2 | Fidelity Select Health Care | 1.14M (3.89%) | 0.00 Increased by 0.00% | Jan 31, 26 |
| 3 | Vanguard Total Stock Mkt Idx Inv | 1.12M (3.82%) | 0.00 Increased by 0.00% | Feb 28, 26 |
| 4 | iShares Russell 2000 ETF | 971.80K (3.32%) | 0.00 Increased by 0.00% | May 31, 25 |
| 5 | Franklin Biotechnology Discovery A | 826.40K (2.82%) | 0.00 Increased by 0.00% | Feb 28, 26 |
| 6 | Franklin Small Cap Growth SMA | 771.94K (2.64%) | 771.94K Increased by +100.00% | Jun 30, 25 |
| 7 | Franklin US Small Cap Growth Equity | 771.94K (2.64%) | 3.97K Increased by +0.51% | Jun 30, 25 |
| 8 | Franklin Small Cap Growth Adv | 708.38K (2.42%) | -59.59K Decreased by -8.41% | Jun 30, 25 |
| 9 | Fidelity Advisor Health Care I | 700.00K (2.39%) | 0.00 Increased by 0.00% | Jan 31, 26 |
| 10 | Fidelity Small Cap Index | 408.40K (1.40%) | 0.00 Increased by 0.00% | May 31, 25 |
| 11 | iShares Russell 2000 Value ETF | 364.32K (1.24%) | 0.00 Increased by 0.00% | May 31, 25 |
| 12 | Vanguard Institutional Extnd Mkt Idx Tr | 335.27K (1.15%) | 10.90K Increased by +3.25% | Feb 28, 26 |
| 13 | Vanguard Russell 2000 ETF | 209.36K (0.72%) | 1.88K Increased by +0.90% | May 31, 25 |
| 14 | State St Russell Sm Cap® Indx SL Cl I | 205.20K (0.70%) | 0.00 Increased by 0.00% | May 31, 25 |
| 15 | Fidelity VIP Health Care Initial | 180.00K (0.61%) | 0.00 Increased by 0.00% | Jan 31, 26 |
| 16 | Fidelity Extended Market Index | 172.30K (0.59%) | -715.00 Decreased by -0.41% | Jan 31, 26 |
| 17 | Fidelity® Extended Market Index | 137.97K (0.47%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 18 | UBC Russell 3000 Index Trust - C | 121.97K (0.42%) | 108.70K Increased by +89.11% | Mar 31, 25 |
| 19 | Schwab Small Cap Index | 116.90K (0.40%) | 0.00 Increased by 0.00% | May 31, 25 |
| 20 | iShares Micro-Cap ETF | 105.26K (0.36%) | 19.87K Increased by +18.88% | Feb 28, 26 |