| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Baker Bros Advisors LP | 27.53M (13.58%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 2 | ING Investment Management LLC | 21.25M (10.48%) | 10.62M Increased by +50.00% | Mar 31, 25 |
| 3 | Capital World Investors | 13.36M (6.59%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 4 | Baillie Gifford & Co Limited. | 10.36M (5.11%) | -835.83K Decreased by -8.07% | Jun 30, 25 |
| 5 | UBS Asset Mgmt Americas Inc | 8.47M (4.18%) | -7.20M Decreased by -84.98% | Jun 30, 25 |
| 6 | Credit Suisse First Boston (CSFB) | 4.55M (2.24%) | -30.93K Decreased by -0.68% | Mar 31, 24 |
| 7 | Two Sigma Investments LLC | 4.11M (2.03%) | 984.06K Increased by +23.94% | Jun 30, 25 |
| 8 | ArrowMark Colorado Holdings, LLC (ArrowMark Partners) | 4.11M (2.02%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 9 | Two Sigma Advisers, LLC | 4.07M (2.01%) | 1.43M Increased by +35.02% | Jun 30, 25 |
| 10 | Founders Fund VII Management, LLC | 3.77M (1.86%) | 0.00 Increased by 0.00% | Jun 30, 24 |
| 11 | BlackRock Inc | 3.68M (1.82%) | 104.59K Increased by +2.84% | Jun 30, 25 |
| 12 | UBS Group AG | 3.45M (1.70%) | -1.63M Decreased by -47.40% | Jun 30, 25 |
| 13 | Millennium Management LLC | 3.40M (1.68%) | 2.53M Increased by +74.40% | Jun 30, 25 |
| 14 | Orbimed Advisors, LLC | 3.34M (1.65%) | -836.20K Decreased by -25.00% | Jun 30, 25 |
| 15 | Renaissance Technologies Corp | 3.31M (1.63%) | 413.40K Increased by +12.50% | Jun 30, 25 |
| 16 | Citadel Advisors Llc | 2.89M (1.43%) | 1.08M Increased by +37.21% | Jun 30, 25 |
| 17 | Prosight Management, LP | 2.82M (1.39%) | -4.53M Decreased by -161.04% | Mar 31, 25 |
| 18 | TANG CAPITAL MANAGEMENT LLC | 2.60M (1.28%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 19 | Casdin Capital, LLC | 2.36M (1.16%) | 0.00 Increased by 0.00% | Mar 31, 24 |
| 20 | Fidelity International Ltd | 1.88M (0.93%) | 1.88M Increased by +100.00% | Dec 31, 23 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | American Funds SMALLCAP World A | 13.36M (6.59%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 2 | Allianz Global Artfcl Intlgc W EUR | 6.17M (3.05%) | -7.81K Decreased by -0.13% | Apr 30, 25 |
| 3 | CS (Lux) Digital Health Equity SB USD | 4.50M (2.22%) | 0.00 Increased by 0.00% | Apr 30, 24 |
| 4 | UBS (Lux) Digital Health Equity SB USD | 4.50M (2.22%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 5 | SMDS Global AI Equity Mother | 4.49M (2.21%) | 0.00 Increased by 0.00% | Mar 25, 25 |
| 6 | Baillie Gifford Positive Change | 3.89M (1.92%) | -143.60K Decreased by -3.69% | Jul 31, 25 |
| 7 | Baillie Gifford Positive Change B Acc | 3.89M (1.92%) | -128.37K Decreased by -3.30% | Jul 31, 25 |
| 8 | UBS Lux Dgtl Hlth Eq Fd seeding P acc | 3.40M (1.68%) | -72.96K Decreased by -2.14% | Jul 31, 25 |
| 9 | American Funds IS® Asset Allocation 1 | 2.87M (1.42%) | 0.00 Increased by 0.00% | Jun 30, 24 |
| 10 | Baillie Gifford WW Pstv Chg B USD Acc | 2.26M (1.11%) | -72.26K Decreased by -3.20% | Jul 31, 25 |
| 11 | ACATIS Datini Valueflex Fonds A | 1.86M (0.92%) | 860.00K Increased by +46.24% | Jul 31, 25 |
| 12 | iShares Biotechnology ETF | 1.34M (0.66%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 13 | Desjardins Global Small Cap Equity A | 1.29M (0.64%) | 22.03K Increased by +1.70% | Jan 31, 24 |
| 14 | Lazard Global Small Cap Equity | 1.29M (0.64%) | 114.74K Increased by +8.88% | Dec 31, 23 |
| 15 | Nissay Glb Digital Hlthcare Equity MF | 974.00K (0.48%) | 149.70K Increased by +15.37% | Nov 20, 23 |
| 16 | Nissay Glbl Digital Hlthcare Eq MF | 962.50K (0.47%) | 139.50K Increased by +14.49% | Nov 18, 24 |
| 17 | Baillie Gifford International Alpha 2 | 835.46K (0.41%) | 0.00 Increased by 0.00% | Jun 30, 24 |
| 18 | BlackRock Global Equity Mkt Netrl Instl | 564.25K (0.28%) | 33.07K Increased by +5.86% | Apr 30, 24 |
| 19 | iShares Genomics Immnlgy & Hlthcr ETF | 557.80K (0.28%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 20 | Old Westbury Small & Mid Cap Strategies | 531.17K (0.26%) | 0.00 Increased by 0.00% | Apr 30, 24 |