| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Baker Bros Advisors LP | 27.53M (13.60%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 2 | ING Investment Management LLC | 21.25M (10.50%) | 10.62M Increased by +50.00% | Mar 31, 25 |
| 3 | UBS Asset Mgmt Americas Inc | 15.67M (7.74%) | 11.17M Increased by +71.28% | Mar 31, 25 |
| 4 | Capital World Investors | 13.36M (6.60%) | 5.43M Increased by +40.62% | Mar 31, 25 |
| 5 | Baillie Gifford & Co Limited. | 11.20M (5.53%) | -1.04M Decreased by -9.29% | Mar 31, 25 |
| 6 | UBS Group AG | 5.08M (2.51%) | 3.11M Increased by +61.13% | Mar 31, 25 |
| 7 | Credit Suisse First Boston (CSFB) | 4.55M (2.25%) | -30.93K Decreased by -0.68% | Mar 31, 24 |
| 8 | Orbimed Advisors, LLC | 4.18M (2.07%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 9 | ArrowMark Colorado Holdings, LLC (ArrowMark Partners) | 4.11M (2.03%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 10 | Founders Fund VII Management, LLC | 3.77M (1.86%) | 0.00 Increased by 0.00% | Jun 30, 24 |
| 11 | BlackRock Inc | 3.58M (1.77%) | -520.43K Decreased by -14.55% | Mar 31, 25 |
| 12 | Two Sigma Investments LLC | 3.13M (1.54%) | -130.52K Decreased by -4.17% | Mar 31, 25 |
| 13 | Renaissance Technologies Corp | 2.89M (1.43%) | 407.14K Increased by +14.07% | Mar 31, 25 |
| 14 | Prosight Management, LP | 2.82M (1.39%) | -4.53M Decreased by -161.04% | Mar 31, 25 |
| 15 | Two Sigma Advisers, LLC | 2.64M (1.31%) | 36.40K Increased by +1.38% | Mar 31, 25 |
| 16 | TANG CAPITAL MANAGEMENT LLC | 2.60M (1.28%) | 17.18K Increased by +0.66% | Mar 31, 25 |
| 17 | Casdin Capital, LLC | 2.36M (1.17%) | 0.00 Increased by 0.00% | Mar 31, 24 |
| 18 | Fidelity International Ltd | 1.88M (0.93%) | 1.88M Increased by +100.00% | Dec 31, 23 |
| 19 | Citadel Advisors Llc | 1.81M (0.90%) | 1.22M Increased by +67.08% | Mar 31, 25 |
| 20 | Guardian Capital Advisors LP | 1.79M (0.88%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | American Funds SMALLCAP World A | 13.36M (6.60%) | 5.43M Increased by +40.62% | Mar 31, 25 |
| 2 | Allianz Global Artfcl Intlgc W EUR | 6.17M (3.05%) | -7.81K Decreased by -0.13% | Apr 30, 25 |
| 3 | CS (Lux) Digital Health Equity SB USD | 4.50M (2.22%) | 0.00 Increased by 0.00% | Apr 30, 24 |
| 4 | UBS (Lux) Digital Health Equity SB USD | 4.50M (2.22%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 5 | SMDS Global AI Equity Mother | 4.49M (2.22%) | 0.00 Increased by 0.00% | Mar 25, 25 |
| 6 | Baillie Gifford Positive Change | 4.35M (2.15%) | -248.26K Decreased by -5.71% | Apr 30, 25 |
| 7 | Baillie Gifford Positive Change B Acc | 4.35M (2.15%) | -277.83K Decreased by -6.39% | Apr 30, 25 |
| 8 | UBS Lux Dgtl Hlth Eq Fd seeding P acc | 4.34M (2.14%) | -158.70K Decreased by -3.66% | Apr 30, 25 |
| 9 | American Funds IS® Asset Allocation 1 | 2.87M (1.42%) | 0.00 Increased by 0.00% | Jun 30, 24 |
| 10 | Baillie Gifford WW Pstv Chg B USD Acc | 2.48M (1.22%) | -39.44K Decreased by -1.59% | Apr 30, 25 |
| 11 | iShares Biotechnology ETF | 1.33M (0.66%) | 0.00 Increased by 0.00% | May 31, 25 |
| 12 | Desjardins Global Small Cap Equity A | 1.29M (0.64%) | 22.03K Increased by +1.70% | Jan 31, 24 |
| 13 | Lazard Global Small Cap Equity | 1.29M (0.64%) | 114.74K Increased by +8.88% | Dec 31, 23 |
| 14 | ACATIS Datini Valueflex Fonds A | 1.00M (0.49%) | 0.00 Increased by 0.00% | Apr 30, 25 |
| 15 | Nissay Glb Digital Hlthcare Equity MF | 974.00K (0.48%) | 149.70K Increased by +15.37% | Nov 20, 23 |
| 16 | Nissay Glbl Digital Hlthcare Eq MF | 962.50K (0.48%) | 139.50K Increased by +14.49% | Nov 18, 24 |
| 17 | Baillie Gifford International Alpha 2 | 835.46K (0.41%) | 0.00 Increased by 0.00% | Jun 30, 24 |
| 18 | Lazard Digital Health | 777.03K (0.38%) | -93.99K Decreased by -12.10% | Mar 31, 25 |
| 19 | BlackRock Global Equity Mkt Netrl Instl | 564.25K (0.28%) | 33.07K Increased by +5.86% | Apr 30, 24 |
| 20 | Old Westbury Small & Mid Cap Strategies | 531.17K (0.26%) | 0.00 Increased by 0.00% | Apr 30, 24 |