| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Baker Bros Advisors LP | 27.53M (13.57%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 2 | Baillie Gifford & Co Limited. | 12.24M (6.03%) | -658.24K Decreased by -5.38% | Dec 31, 24 |
| 3 | ING Investment Management LLC | 10.62M (5.24%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 4 | Capital World Investors | 7.93M (3.91%) | 7.93M Increased by +100.00% | Dec 31, 24 |
| 5 | Prosight Management, LP | 7.35M (3.62%) | -1.73M Decreased by -23.53% | Dec 31, 24 |
| 6 | Credit Suisse First Boston (CSFB) | 4.55M (2.24%) | -30.93K Decreased by -0.68% | Mar 31, 24 |
| 7 | UBS Asset Mgmt Americas Inc | 4.50M (2.22%) | -90.10K Decreased by -2.00% | Dec 31, 24 |
| 8 | Orbimed Advisors, LLC | 4.18M (2.06%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 9 | ArrowMark Colorado Holdings, LLC (ArrowMark Partners) | 4.11M (2.02%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 10 | BlackRock Inc | 4.10M (2.02%) | 107.95K Increased by +2.64% | Dec 31, 24 |
| 11 | Founders Fund VII Management, LLC | 3.77M (1.86%) | 0.00 Increased by 0.00% | Jun 30, 24 |
| 12 | Two Sigma Investments LLC | 3.26M (1.61%) | 723.68K Increased by +22.22% | Dec 31, 24 |
| 13 | Two Sigma Advisers, LLC | 2.61M (1.29%) | 430.80K Increased by +16.52% | Dec 31, 24 |
| 14 | TANG CAPITAL MANAGEMENT LLC | 2.58M (1.27%) | 282.82K Increased by +10.95% | Dec 31, 24 |
| 15 | Renaissance Technologies Corp | 2.49M (1.23%) | -459.81K Decreased by -18.49% | Dec 31, 24 |
| 16 | Casdin Capital, LLC | 2.36M (1.16%) | 0.00 Increased by 0.00% | Mar 31, 24 |
| 17 | Federated Hermes Inc | 2.28M (1.13%) | -443.32K Decreased by -19.42% | Sep 30, 24 |
| 18 | UBS Group AG | 1.98M (0.97%) | 1.95M Increased by +98.90% | Dec 31, 24 |
| 19 | Fidelity International Ltd | 1.88M (0.92%) | 1.88M Increased by +100.00% | Dec 31, 23 |
| 20 | Guardian Capital Advisors LP | 1.79M (0.88%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | American Funds SMALLCAP World A | 7.93M (3.91%) | 7.93M Increased by +100.00% | Dec 31, 24 |
| 2 | Allianz Global Artfcl Intlgc W EUR | 6.13M (3.02%) | 31.13K Increased by +0.51% | Feb 28, 25 |
| 3 | Baillie Gifford Positive Change B Acc | 4.51M (2.22%) | 15.75K Increased by +0.35% | Jan 31, 25 |
| 4 | CS (Lux) Digital Health Equity SB USD | 4.50M (2.22%) | 0.00 Increased by 0.00% | Apr 30, 24 |
| 5 | UBS (Lux) Digital Health Equity SB USD | 4.50M (2.22%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 6 | SMDS Global AI Equity Mother | 4.49M (2.21%) | 0.00 Increased by 0.00% | Sep 25, 24 |
| 7 | Baillie Gifford Positive Change | 4.49M (2.21%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 8 | American Funds IS® Asset Allocation 1 | 2.87M (1.42%) | 0.00 Increased by 0.00% | Jun 30, 24 |
| 9 | Baillie Gifford WW Pstv Chg B USD Acc | 2.64M (1.30%) | -9.80K Decreased by -0.37% | Jan 31, 25 |
| 10 | iShares Biotechnology ETF | 1.43M (0.71%) | -15.93K Decreased by -1.11% | Mar 31, 25 |
| 11 | Desjardins Global Small Cap Equity A | 1.29M (0.64%) | 22.03K Increased by +1.70% | Jan 31, 24 |
| 12 | Lazard Global Small Cap Equity | 1.29M (0.64%) | 114.74K Increased by +8.88% | Dec 31, 23 |
| 13 | ACATIS Datini Valueflex Fonds A | 1.00M (0.49%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 14 | Nissay Glb Digital Hlthcare Equity MF | 974.00K (0.48%) | 149.70K Increased by +15.37% | Nov 20, 23 |
| 15 | Nissay Glbl Digital Hlthcare Eq MF | 962.50K (0.47%) | 139.50K Increased by +14.49% | Nov 18, 24 |
| 16 | Lazard Digital Health | 871.02K (0.43%) | -164.67K Decreased by -18.91% | Dec 31, 24 |
| 17 | Baillie Gifford International Alpha 2 | 835.46K (0.41%) | 0.00 Increased by 0.00% | Jun 30, 24 |
| 18 | BlackRock Global Equity Mkt Netrl Instl | 564.25K (0.28%) | 33.07K Increased by +5.86% | Apr 30, 24 |
| 19 | Mediolanum BB Global Impact L | 555.38K (0.27%) | 0.00 Increased by 0.00% | Mar 31, 24 |
| 20 | Old Westbury Small & Mid Cap Strategies | 531.17K (0.26%) | 0.00 Increased by 0.00% | Apr 30, 24 |