| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | venBio Select Advisor LLC | 2.85M (34.30%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 2 | Qvt Financial LP | 2.31M (27.85%) | 2.31M Increased by +100.00% | Dec 31, 24 |
| 3 | BML Capital Management LLC | 2.10M (25.28%) | 100.00K Increased by +4.76% | Dec 31, 24 |
| 4 | Longwood Capital Partners LLC | 1.85M (22.26%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 5 | SATTER MANAGEMENT CO., L.P. | 1.63M (19.63%) | 0.00 Increased by 0.00% | Jun 30, 24 |
| 6 | Ally Bridge Group (NY) LLC | 817.94K (9.85%) | 817.94K Increased by +100.00% | Dec 31, 24 |
| 7 | HHG PLC | 780.37K (9.39%) | 248.73K Increased by +31.87% | Sep 30, 23 |
| 8 | Vanguard Group Inc | 765.99K (9.22%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 9 | Decheng Capital LLC | 526.33K (6.34%) | 0.00 Increased by 0.00% | Mar 31, 24 |
| 10 | Vivo Capital, LLC | 509.57K (6.13%) | 0.00 Increased by 0.00% | Jun 30, 24 |
| 11 | Renaissance Technologies Corp | 456.02K (5.49%) | -5.80K Decreased by -1.27% | Dec 31, 24 |
| 12 | Peapod Lane Capital LLC | 442.94K (5.33%) | 442.94K Increased by +100.00% | Dec 31, 24 |
| 13 | Acuitas Investments, LLC | 438.76K (5.28%) | 86.28K Increased by +19.66% | Sep 30, 24 |
| 14 | State Street Corporation | 375.15K (4.52%) | 60.24K Increased by +16.06% | Mar 31, 24 |
| 15 | EcoR1 Capital, LLC | 345.25K (4.16%) | -1.50M Decreased by -434.46% | Dec 31, 24 |
| 16 | Soleus Capital Management, L.P. | 333.23K (4.01%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 17 | ExodusPoint Capital Management, LP | 307.76K (3.70%) | 171.25K Increased by +55.64% | Sep 30, 23 |
| 18 | Baker Bros Advisors LP | 251.73K (3.03%) | -738.20K Decreased by -293.25% | Dec 31, 23 |
| 19 | Ghost Tree Capital, LLC | 250.00K (3.01%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 20 | BlackRock Inc | 243.89K (2.94%) | 1.00K Increased by +0.41% | Dec 31, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 499.93K (6.02%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 2 | iShares Russell 2000 ETF | 377.52K (4.54%) | -3.01K Decreased by -0.80% | Apr 30, 24 |
| 3 | Vanguard Institutional Extnd Mkt Idx Tr | 247.52K (2.98%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 4 | Fidelity Small Cap Index | 163.74K (1.97%) | 7.96K Increased by +4.86% | Jun 30, 24 |
| 5 | Fidelity® Small Cap Index | 155.04K (1.87%) | 4.70K Increased by +3.03% | Oct 31, 23 |
| 6 | iShares Russell 2000 Value ETF | 142.52K (1.72%) | 0.00 Increased by 0.00% | Apr 30, 24 |
| 7 | State St Russell Sm/Mid Cp® Indx NL Cl C | 136.75K (1.65%) | -15.55K Decreased by -11.37% | Jun 30, 24 |
| 8 | T. Rowe Price Health Sciences | 123.56K (1.49%) | -12.08K Decreased by -9.78% | Sep 30, 23 |
| 9 | Bridgeway Ultra-Small Company | 115.40K (1.39%) | 22.10K Increased by +19.15% | Dec 31, 24 |
| 10 | Fidelity Extended Market Index | 112.93K (1.36%) | -719.00 Decreased by -0.64% | Feb 28, 25 |
| 11 | Fidelity® Extended Market Index | 108.52K (1.31%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 12 | Vanguard Russell 2000 ETF | 60.84K (0.73%) | 1.96K Increased by +3.23% | Mar 31, 24 |
| 13 | BlackRock Extended Mkt Composite | 51.08K (0.61%) | 284.00 Increased by +0.56% | Sep 30, 23 |
| 14 | State St Russell Sm Cap® Indx SL Cl I | 49.69K (0.60%) | 0.00 Increased by 0.00% | Apr 30, 24 |
| 15 | BlackRock Extended Equity Market K | 44.10K (0.53%) | -19.00 Decreased by -0.04% | Sep 30, 24 |
| 16 | Extended Equity Market Fund K | 43.63K (0.53%) | 134.00 Increased by +0.31% | Mar 31, 25 |
| 17 | NT R2000 Value Index Fund - NL | 42.75K (0.51%) | -1.51K Decreased by -3.52% | Dec 31, 23 |
| 18 | NT R2000 Index Fund - NL | 41.47K (0.50%) | -836.00 Decreased by -2.02% | Jun 30, 24 |
| 19 | iShares Micro-Cap ETF | 38.08K (0.46%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 20 | Schwab Small Cap Index | 37.08K (0.45%) | 0.00 Increased by 0.00% | Mar 31, 24 |